Search Hotels Near Roper St. Francis Mount Pleasant Hospital, Mount Pleasant

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Our top choices for Roper St. Francis Mount Pleasant Hospital hotels

Exterior
Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG

Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG

Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG
2.5 star property
6.7 km from Roper St. Francis Mount Pleasant Hospital
9.0 out of 10, Wonderful, (1000)
"Everything about my stay here has been a delight, clean room, professional & friendly staff "
United States
John
The price is ฿2,768
฿3,128 total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG
Restaurant
Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms

Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms

Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms
2.5 star property
7.3 km from Roper St. Francis Mount Pleasant Hospital
9.0 out of 10, Wonderful, (1000)
"Great place to stay!!!"
United States
Fredrick
The price is ฿2,728
฿3,150 total
includes taxes & fees
11 Jan - 12 Jan 2026
Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms
American cuisine
Cambria Hotel Mount Pleasant – Charleston

Cambria Hotel Mount Pleasant – Charleston

Cambria Hotel Mount Pleasant – Charleston
3.0 star property
9.8 km from Roper St. Francis Mount Pleasant Hospital
9.4 out of 10, Exceptional, (1809)
"Beautiful room, good staff"
United States
Queen
The price is ฿2,915
฿3,362 total
includes taxes & fees
4 Jan - 5 Jan 2026
Cambria Hotel Mount Pleasant – Charleston
Exterior
Home2 Suites By Hilton Mt Pleasant Charleston

Home2 Suites By Hilton Mt Pleasant Charleston

Home2 Suites By Hilton Mt Pleasant Charleston
3.0 star property
8.1 km from Roper St. Francis Mount Pleasant Hospital
8.8 out of 10, Excellent, (999)
"Staff very courteous and area vey clean"
United States
Cuahutemoe
The price is ฿3,070
฿3,469 total
includes taxes & fees
22 Dec - 23 Dec
Home2 Suites By Hilton Mt Pleasant Charleston
Bar (on property)
Hyatt Place Mount Pleasant Towne Centre

Hyatt Place Mount Pleasant Towne Centre

Hyatt Place Mount Pleasant Towne Centre
3.0 star property
7.8 km from Roper St. Francis Mount Pleasant Hospital
9.0 out of 10, Wonderful, (1003)
"Nice place"
United States
Marcelle
The price is ฿3,146
฿3,938 total
includes taxes & fees
9 Jan - 10 Jan 2026
Hyatt Place Mount Pleasant Towne Centre
Lobby
Tru by Hilton Mt Pleasant Charleston

Tru by Hilton Mt Pleasant Charleston

Tru by Hilton Mt Pleasant Charleston
2.5 star property
9.4 km from Roper St. Francis Mount Pleasant Hospital
9.2 out of 10, Wonderful, (1459)
"It was a great hotel!"
United States
Alashia
The price is ฿2,812
฿3,240 total
includes taxes & fees
1 Jan - 2 Jan 2026
Tru by Hilton Mt Pleasant Charleston
Free daily full breakfast
Residence Inn by Marriott Charleston Mount Pleasant

Residence Inn by Marriott Charleston Mount Pleasant

Residence Inn by Marriott Charleston Mount Pleasant
3.0 star property
7.2 km from Roper St. Francis Mount Pleasant Hospital
8.8 out of 10, Excellent, (183)
"Property was quiet and clean. It was convenient to dining and shopping options. Pool was very well maintained and breakfast was well-stocked and excellent each morning. "
United States
Holly
The price is ฿3,712
฿4,195 total
includes taxes & fees
24 Dec - 25 Dec
Residence Inn by Marriott Charleston Mount Pleasant
Restaurant
Homewood Suites by Hilton Charleston - Mt Pleasant

Homewood Suites by Hilton Charleston - Mt Pleasant

Homewood Suites by Hilton Charleston - Mt Pleasant
3.0 star property
7.5 km from Roper St. Francis Mount Pleasant Hospital
8.4 out of 10, Very good, (1003)
"Courteous staff and great location"
United States
Loushon
The price is ฿3,248
฿3,733 total
includes taxes & fees
31 Dec - 1 Jan 2026
Homewood Suites by Hilton Charleston - Mt Pleasant
Exterior
Comfort Suites at Isle Of Palms Connector

Comfort Suites at Isle Of Palms Connector

Comfort Suites at Isle Of Palms Connector
2.5 star property
7.4 km from Roper St. Francis Mount Pleasant Hospital
8.2 out of 10, Very good, (1002)
"The staff was friendly and the room was exceptionally clean. "
United States
RAYMOND
The price is ฿2,614
฿3,108 total
includes taxes & fees
4 Jan - 5 Jan 2026
Comfort Suites at Isle Of Palms Connector
Lobby lounge
Courtyard by Marriott Charleston Mount Pleasant

Courtyard by Marriott Charleston Mount Pleasant

Courtyard by Marriott Charleston Mount Pleasant
3.0 star property
9.4 km from Roper St. Francis Mount Pleasant Hospital
8.8 out of 10, Excellent, (1000)
"We had a very restful stay. The lady that checked us in was very nice. The room was very clean and the beds were comfortable. "
United States
Kathryn
The price is ฿3,177
฿3,591 total
includes taxes & fees
24 Dec - 25 Dec
Courtyard by Marriott Charleston Mount Pleasant
Bar (on property)
Hyatt House Charleston / Mount Pleasant

Hyatt House Charleston / Mount Pleasant

Hyatt House Charleston / Mount Pleasant
3.5 star property
9.8 km from Roper St. Francis Mount Pleasant Hospital
9.2 out of 10, Wonderful, (1000)
"Good value and great location."
United States
Howard
The price is ฿3,398
฿3,910 total
includes taxes & fees
6 Jan - 7 Jan 2026
Hyatt House Charleston / Mount Pleasant
Dining
DoubleTree by Hilton Charleston Mount Pleasant

DoubleTree by Hilton Charleston Mount Pleasant

DoubleTree by Hilton Charleston Mount Pleasant
4.0 star property
10.7 km from Roper St. Francis Mount Pleasant Hospital
9.2 out of 10, Wonderful, (1005)
"Room was nice and staff was very friendly."
United States
Viorel
The price is ฿2,760
฿3,182 total
includes taxes & fees
22 Dec - 23 Dec
DoubleTree by Hilton Charleston Mount Pleasant
Studio, 2 Queen Beds | Private kitchen | Fridge, microwave, stovetop, dishwasher
TownePlace Suites Charleston Mt. Pleasant

TownePlace Suites Charleston Mt. Pleasant

TownePlace Suites Charleston Mt. Pleasant
3.0 star property
10.7 km from Roper St. Francis Mount Pleasant Hospital
9.0 out of 10, Wonderful, (523)
"Great place to stay. Dog friendly. "
United States
Gabriela
The price is ฿3,461
฿3,910 total
includes taxes & fees
25 Dec - 26 Dec
TownePlace Suites Charleston Mt. Pleasant
5 outdoor pools, open 7:00 AM to 10:00 PM, pool cabanas (surcharge)
Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn

Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn

Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn
4.0 star property
8.6 km from Roper St. Francis Mount Pleasant Hospital
8.8 out of 10, Excellent, (1004)
"Great Stay!"
United States
Doug
The price is ฿6,544
฿8,797 total
includes taxes & fees
18 Dec - 19 Dec
Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn
Premium Room, 1 King Bed (Upgraded Bedding & Snack, Smoke Free) | Desk, laptop workspace, blackout curtains, free WiFi
Red Roof Inn PLUS+ Mt Pleasant - Patriots Point

Red Roof Inn PLUS+ Mt Pleasant - Patriots Point

Red Roof Inn PLUS+ Mt Pleasant - Patriots Point
2.5 star property
14.4 km from Roper St. Francis Mount Pleasant Hospital
6.8 out of 10, (1003)
"Room was very clean and staff was also very nice."
United States
Chris
The price is ฿2,095
฿2,368 total
includes taxes & fees
14 Jan - 15 Jan 2026
Red Roof Inn PLUS+ Mt Pleasant - Patriots Point
In-room safe, desk, laptop workspace, blackout curtains
The Palms Oceanfront Hotel

The Palms Oceanfront Hotel

The Palms Oceanfront Hotel
3.5 star property
10.4 km from Roper St. Francis Mount Pleasant Hospital
8.2 out of 10, Very good, (1063)
"Very clean and location was great!! "
United States
Clarisa
The Palms Oceanfront Hotel
Lobby
Hampton Inn Charleston - Daniel Island

Hampton Inn Charleston - Daniel Island

Hampton Inn Charleston - Daniel Island
2.5 star property
13.7 km from Roper St. Francis Mount Pleasant Hospital
9.0 out of 10, Wonderful, (1002)
"Nice hotel, safe, quiet"
United States
Todd
The price is ฿3,070
฿3,500 total
includes taxes & fees
2 Jan - 3 Jan 2026
Hampton Inn Charleston - Daniel Island
Terrace/patio
Home2 Suites by Hilton Charleston Daniel Island

Home2 Suites by Hilton Charleston Daniel Island

Home2 Suites by Hilton Charleston Daniel Island
3.0 star property
13.5 km from Roper St. Francis Mount Pleasant Hospital
9.4 out of 10, Exceptional, (500)
"So clean, great amenities and excellent breakfast. "
United States
Susan
The price is ฿3,844
฿4,382 total
includes taxes & fees
2 Jan - 3 Jan 2026
Home2 Suites by Hilton Charleston Daniel Island
Terrace/patio
Holiday Inn Express & Suites Mt. Pleasant by IHG

Holiday Inn Express & Suites Mt. Pleasant by IHG

Holiday Inn Express & Suites Mt. Pleasant by IHG
3.5 star property
14.2 km from Roper St. Francis Mount Pleasant Hospital
9.2 out of 10, Wonderful, (1009)
"Great room layout and wonderful breakfast. "
United States
Clara
The price is ฿2,706
฿3,129 total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express & Suites Mt. Pleasant by IHG
Ballroom
Staybridge Suites Charleston - Mount Pleasant by IHG

Staybridge Suites Charleston - Mount Pleasant by IHG

Staybridge Suites Charleston - Mount Pleasant by IHG
3.0 star property
14.6 km from Roper St. Francis Mount Pleasant Hospital
9.4 out of 10, Exceptional, (1002)
"This is a wonderful place to stay it was very clean, the staff was very friendly, the view of the bridge was really a nice touch. "
United States
Paula
The price is ฿3,461
฿3,979 total
includes taxes & fees
24 Dec - 25 Dec
Staybridge Suites Charleston - Mount Pleasant by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Roper St. Francis Mount Pleasant Hospital Hotel Reviews

Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn

Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn

10/10 Excellent
"Great resort, beautiful beach, ton of restaurant and food options. Close enough to Charleston for a day trip to town. Would highly recommend. "
Jawad 3-night trip
Posted 4 days ago
Wild Dunes Resort – Sweetgrass Inn and Boardwalk Inn

Hotels near other Roper St. Francis Mount Pleasant Hospital attractions

Boone Hall Plantation and Gardens

4.6/5 (518 reviews)
Find out about the history of Mount Pleasant with a stop at Boone Hall Plantation and Gardens. Stroll along the area's waterfront or simply savour its top-notch restaurants.
See properties

Charleston National Golf Club

5.0/5 (1 review)
Enjoy a round of golf in Mount Pleasant at Charleston National Golf Club. Visit the top-notch restaurants or lively bars in this walkable area.
See properties

Frequently asked questions

What's the area like around Roper St. Francis Mount Pleasant Hospital?
Roper St. Francis Mount Pleasant Hospital is located in Mount Pleasant. This historic area is known for its stunning river views and array of dining options. You'll find 66 hotels and other accommodations within a few miles for a convenient home base.
What's the best hotel to stay near Roper St. Francis Mount Pleasant Hospital?
Holiday Inn Express & Suites Charleston NE Mt Pleasant US17 by IHG is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and free parking. It's located 4.1 mi (6.7 km) from Roper St. Francis Mount Pleasant Hospital. Other good options within 5 miles include Comfort Suites at Isle Of Palms Connector and Hampton Inn & Suites Charleston/Mt. Pleasant-Isle Of Palms.
How many hotels can I expect to find near Roper St. Francis Mount Pleasant Hospital?
Expedia has 66 hotels and other accommodation options a few miles from Roper St. Francis Mount Pleasant Hospital.
If I need to cancel the hotel reservation for my stay near Roper St. Francis Mount Pleasant Hospital, will I receive a refund?
Yes! You'll find that most hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and be given a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the "fully refundable" filter to view the best deals available near Roper St. Francis Mount Pleasant Hospital.
What can I see and do near Roper St. Francis Mount Pleasant Hospital?
You can enjoy nature at Goat Island, Dewees Island Beach or Palmetto Islands County Park. Dunes West Golf and River Club, Charleston National Golf Club or Snee Farm Country Club are some local sights worth checking out. If you want to see more of the surrounding area, you can plan a visit to Mount Pleasant Towne Centre and Shipyard Park.