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Our top choices for Rochester hotels with a spa

Presidential Suite, Multiple Beds | Living area | 55-inch LCD TV with satellite channels, TV

Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area
3.5 star property
Downtown Rochester
9.6 out of 10, Exceptional, (618 reviews)
  • cleanliness
    Soothing spa treatments and daily wellness rituals await at this city centre Rochester retreat with an indoor pool and hot tub.
The price is ฿5,706
฿6,569 total
includes taxes & fees
31 Jul - 1 Aug
Hilton Rochester Mayo Clinic Area
Serves lunch, dinner and happy hour

AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic
3.0 star property
Rochester
8.0 out of 10, Very good, (1,385 reviews)
  • cleanliness
    Rejuvenating spa retreats with daily treatments, hot tub relaxation, and attentive staff await at this hotel.
The price is ฿2,621
฿3,017 total
includes taxes & fees
10 Aug - 11 Aug
AmericInn by Wyndham Rochester Near Mayo Clinic
Indoor pool, pool cabanas (surcharge), pool loungers

Treasure Island Resort & Casino

Treasure Island Resort & Casino
3.0 star property
Welch
8.6 out of 10, Excellent, (450 reviews)
The price is ฿3,006
฿3,726 total
includes taxes & fees
14 Jul - 15 Jul
Treasure Island Resort & Casino
Body treatments, facials

St James Hotel, a Historic Hotel of America

St James Hotel, a Historic Hotel of America
3.5 star property
Red Wing
9.2 out of 10, Wonderful, (1,011 reviews)
  • cleanliness
    Rejuvenate at this historic riverside hotel where the full-service spa offers massages and facials for ultimate relaxation.
The price is ฿5,663
฿6,447 total
includes taxes & fees
16 Jul - 17 Jul
St James Hotel, a Historic Hotel of America
Porch

Round Barn Farm B & B Event Center

Round Barn Farm B & B Event Center
3.5 star property
Red Wing
10.0 out of 10, Exceptional, (49 reviews)
  • cleanliness
    Relax in a charming bed & breakfast with private hot tubs and deep-tissue massages, surrounded by a peaceful garden setting.
The price is ฿8,234
฿8,841 total
includes taxes & fees
6 Aug - 7 Aug
Round Barn Farm B & B Event Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Choose what matters most at spa hotels in Rochester

Pool
Breakfast included

Top Rochester Hotel Reviews

Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

10/10 Excellent
"I love everything about it. I stay here atleast 2 to 3 times a month and always have a very good experience. Staff is always pleasant except for my last stay from 06/25 - 06/31. There was a lady working the breakfast area was rude and closed the breakfast are early. I have never seen that behavior from Any staff members since I started staying since 2025 as I regularly go to Mayo/St Mary's. I hope she will not be there or change her attitude when I return. Room 109"
Shereen 5-night trip
Posted 8 hours ago
Med City Inn & Suites - Mayo Clinic Area

Frequently asked questions

Looking to holiday at a spa hotel in Rochester?
Book one of our fantastic spa hotels and treat yourself from the moment you arrive. Travellers highly recommend Rochester for its array of shops and gourmet restaurants—your day tour starts here. Enjoy the opera and cafes during your holiday. Spa hotels are a great way to take a break from your daily routine and add a layer of luxury to your holiday.
What is the best spa hotel in Rochester?
AmericInn by Wyndham Rochester Near Mayo Clinic is a top spa hotel featuring a 24-hour fitness centre, a bar, an indoor pool and a restaurant. Enjoy the hot tub at the on-site spa. Another popular spa hotel in Rochester is Hilton Rochester Mayo Clinic Area.
How many spa hotels are there in Rochester?
Among Expedia's 352 accommodation options in Rochester, there are 2 spa hotels.
What's there to see and do in Rochester?
Enjoy all that Rochester has to offer when you visit Mayo Civic Center, Soldiers Field Veterans Memorial and Plummer House. If you have extra time while you're in the area, you might want to see Olmsted County Fairgrounds and Apache Mall.
What is a Rochester spa hotel?
Spa hotels in Rochester have full on-site spas and offer services such as massages and a choice of body treatments. Some also provide a selection of in-room treatments for the ultimate luxury. Spa hotels are a must if you want to give yourself an extra treat while on holiday.