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Check prices for these dates

Tonight
9 Mar - 10 Mar
Tomorrow
10 Mar - 11 Mar
This weekend
13 Mar - 15 Mar
Next weekend
20 Mar - 22 Mar

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Our top choices for Poplar Bluff Regional Medical Center hotels

Lobby lounge

Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
3.0 star property
0.2 km from Poplar Bluff Regional Medical Center
9.4 out of 10, Exceptional, (876 reviews)
"Very clean and well maintained hotel. "
United States
Michael
The price is ฿3,506
฿3,961 total
includes taxes & fees
15 Mar - 16 Mar
Fairfield Inn & Suites by Marriott Poplar Bluff
Reception

Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff
2.5 star property
1.3 km from Poplar Bluff Regional Medical Center
9.4 out of 10, Exceptional, (805 reviews)
"Would stay again"
United States
David
The price is ฿3,084
฿3,453 total
includes taxes & fees
22 Mar - 23 Mar
Hampton Inn Poplar Bluff
Lobby

Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
3.0 star property
1.8 km from Poplar Bluff Regional Medical Center
9.2 out of 10, Wonderful, (1,003 reviews)
"Great location and room "
United States
Curtis
The price is ฿2,996
฿3,384 total
includes taxes & fees
15 Mar - 16 Mar
Drury Inn & Suites Poplar Bluff
Breakfast, lunch, dinner served; Italian cuisine

Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG
3.0 star property
1 km from Poplar Bluff Regional Medical Center
8.8 out of 10, Excellent, (722 reviews)
"Enjoyed the stay"
United States
Ranora
The price is ฿2,964
฿3,349 total
includes taxes & fees
15 Mar - 16 Mar
Holiday Inn Poplar Bluff by IHG
Coffee service

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO
2.0 star property
2.1 km from Poplar Bluff Regional Medical Center
8.0 out of 10, Very good, (1,007 reviews)
"Very clean and staff was very friendly!"
United States
Sherry
The price is ฿2,231
฿2,354 total
includes taxes & fees
11 Mar - 12 Mar
Motel 6 Poplar Bluff, MO
Lobby

Comfort Inn Poplar Bluff North

Comfort Inn Poplar Bluff North
2.5 star property
1.6 km from Poplar Bluff Regional Medical Center
7.8 out of 10, Good, (405 reviews)
"Everything is fine "
United States
Bob
The price is ฿2,844
฿3,213 total
includes taxes & fees
15 Mar - 16 Mar
Comfort Inn Poplar Bluff North
Lobby

Super 8 by Wyndham Poplar Bluff Missouri

Super 8 by Wyndham Poplar Bluff Missouri
2.0 star property
1.1 km from Poplar Bluff Regional Medical Center
6.6 out of 10, (636 reviews)
"Very clean and staff was great"
United States
Dawn
The price is ฿1,869
฿2,112 total
includes taxes & fees
17 Mar - 18 Mar
Super 8 by Wyndham Poplar Bluff Missouri
Courtyard

Bullwinkles Rustic Lodge

Bullwinkles Rustic Lodge
2.5 star property
5.6 km from Poplar Bluff Regional Medical Center
8.4 out of 10, Very good, (213 reviews)
"Great stay highly recommend "
United States
Brenden
Bullwinkles Rustic Lodge
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Poplar Bluff Regional Medical Center Hotel Reviews

Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

10/10 Excellent
"This was our third stay at this Motel 6. It’s a great hotel with friendly staff, clean rooms and good location. Pets stay free!"
Amy 1-night trip
Posted 3 hours ago
Motel 6 Poplar Bluff, MO

Hotels near other Poplar Bluff Regional Medical Center attractions

Lake Wappapello State Park

You can take time to visit Lake Wappapello State Park during your travels to Wappapello.
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North Main Street Historic District

You can find out about the history of Poplar Bluff when you stop by North Main Street Historic District. While in this family-friendly area, you can enjoy the restaurants.
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Frequently asked questions

What's the area like around Poplar Bluff Regional Medical Center?
Poplar Bluff Regional Medical Center is located in Poplar Bluff. Travellers like this family-friendly area for its restaurants. You'll find 19 hotels and other accommodations within a few miles for a convenient home base.
Where is the best place to stay near Poplar Bluff Regional Medical Center?
Adjacent to Poplar Bluff Regional Medical Center, Fairfield Inn & Suites by Marriott Poplar Bluff is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. Other good choices within a short distance include Holiday Inn Poplar Bluff by IHG and Hampton Inn Poplar Bluff.
How many hotels will I be able to find close to Poplar Bluff Regional Medical Center?
Expedia has 19 hotels and other accommodation options a few miles from Poplar Bluff Regional Medical Center.
If I need to cancel the hotel reservation for my stay near Poplar Bluff Regional Medical Center, will I receive a refund?
Yes, most hotel room reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to view the best deals available near Poplar Bluff Regional Medical Center.
What can I see and do near Poplar Bluff Regional Medical Center?
You'll want to browse the exhibits at Mo-Ark Regional Railroad Museum and Margaret Harwell Art Museum. You might plan a visit to Black River Coliseum or Ozark Ridge Golf Course while you're in the area. A visit to North Main Street Historic District is worth the trip when you're visiting.