Search Spa Hotels in Perissa

Start date: Check-in selected.
To Date
End date: Check-out
  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check availability on Perissa Spa Hotels

Next weekend
In two weeks

Our top choices for Perissa hotels with a spa

Santorini Studios Pleasure By The Sea

Santorini Studios Pleasure By The Sea
Santorini
8.0 out of 10, Very good, (2)
"Loved the rooms, loved the area, it’s not crowded like Fira or Oia, a lot of retauranats. Easy access to the black rocky beach. Thank Natasha for the beautiful stay. "
United States
Amine
The price is ฿2,302
฿2,632 total
includes taxes & fees
29 Dec - 30 Dec
Santorini Studios Pleasure By The Sea

Irigeneia Hotel

Irigeneia Hotel
4.0 star property
Santorini
9.4 out of 10, Exceptional, (137)
"Excellent location, very comfortable rooms, clean with nice view. Delicious breakfast and an excellent service, here you have the privilege to be attended by the owners, they a magnificent job."
United States
Wilson
The price is ฿2,374
฿2,806 total
includes taxes & fees
15 Jan - 16 Jan 2026
Irigeneia Hotel

Zen Suites & Spa

Zen Suites & Spa
5.0 star property
Santorini
The price is ฿8,220
฿9,481 total
includes taxes & fees
28 Dec - 29 Dec
Zen Suites & Spa

Summer Lovers Villa

Summer Lovers Villa
Santorini
9.6 out of 10, Exceptional, (18)
"We booked the entire villa for our family and even exchanged our vows on the property—it was truly magical. Miss Marita was amazing, taking care of us in every possible way. We couldn’t have been happier with our stay and hope to return soon. If you’re looking for a private, unforgettable family getaway, I highly recommend Summer Lovers Villa."
United States
zuzana
The price is ฿4,053
฿4,621 total
includes taxes & fees
10 Jan - 11 Jan 2026
Summer Lovers Villa

Elements Cave Suites

Elements Cave Suites
Santorini
9.2 out of 10, Wonderful, (16)
"Lovely place to stay in a quiet area that still has great restaurants and some shops around. "
United Kingdom
Kyle Schulz
The price is ฿2,380
฿2,722 total
includes taxes & fees
17 Jan - 18 Jan 2026
Elements Cave Suites

Ira Hotel & Spa - Adults Only

Ira Hotel & Spa - Adults Only
4.0 star property
Santorini
9.4 out of 10, Exceptional, (1000)
"Cleaning service provided daily, all hotel staff was very kind and professional. "
United States
EBONY
The price is ฿3,088
฿3,617 total
includes taxes & fees
20 Jan - 21 Jan 2026
Ira Hotel & Spa - Adults Only

Dreams Luxury Suites

Dreams Luxury Suites
Santorini
9.8 out of 10, Exceptional, (192)
"We had an amazing stay here. It’s the perfect location and the staff was so nice !!! "
Canada
Isabella
The price is ฿6,775
฿7,712 total
includes taxes & fees
5 Jan - 6 Jan 2026
Dreams Luxury Suites

Theoxenia Caldera Hotel

Theoxenia Caldera Hotel
3.0 star property
Santorini
9.2 out of 10, Wonderful, (269)
"Room was very comfortable, staffs were great!!"
United States
Amirthalingadoss
Theoxenia Caldera Hotel

Nefeles Luxury Suites

Nefeles Luxury Suites
Santorini
9.6 out of 10, Exceptional, (164)
"Panos the manager was amazing & very attentive. The view was amazing & breakfast was delicious. "
United States
Sydney
Nefeles Luxury Suites

De Sol Spa Hotel

De Sol Spa Hotel
5.0 star property
Santorini
9.4 out of 10, Exceptional, (525)
"The rooms were clean and the service outstanding. "
United States
Teresa
The price is ฿5,597
฿6,503 total
includes taxes & fees
28 Dec - 29 Dec
De Sol Spa Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Perissa Hotel Reviews

Frequently asked questions

Looking for a spa hotel in Perissa?
Book one of our lush spa hotels and pamper yourself from the moment you arrive. Travellers love the beaches in Perissa. Hotels with spas are the perfect way to break out of your daily routine and add a layer of luxury to your weekend away.
What is the best spa hotel in Perissa?
Antoperla Luxury Hotel & Spa is a top beach spa hotel featuring a fitness centre, a bar, an outdoor pool and a restaurant. Treat yourself to a body scrub, body treatment or massage at the on-site spa. In-room massages are also available. Other popular spa hotels in Perissa include Veggera Hotel and Anastasia Princess Luxury Beach Residence, Adults Only.
How many spa hotels will I find in Perissa?
Among Expedia's 257 accommodation options in Perissa, there are 12 spa hotels.
What's there to see and do in Perissa?
Take in the sights and attractions that Perissa offers with a visit to Perissa Beach, Ancient Thira and Museum of Minerals and Fossils. If you have some spare time during your trip, you might want to check out Kamari Beach and Perivolos Beach.
What is a Perissa spa hotel?
Spa hotels in Perissa provide lodging and have an on-site spa offering services including couples massages as well as body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation and relaxation.