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Our top choices for Penrose hotels

Hyatt Regency St. Louis at The Arch
Hyatt Regency St. Louis at The Arch
Moonrise Hotel
Moonrise Hotel
Holiday Inn Express & Suites - O'Fallon /Shiloh by IHG
Holiday Inn Express & Suites - O'Fallon /Shiloh by IHG
Live by Loews - St.Louis
Live by Loews - St.Louis
Fairfield Inn & Suites by Marriott St. Louis Downtown
Fairfield Inn & Suites by Marriott St. Louis Downtown
Pear Tree Inn St. Louis Convention Center
Pear Tree Inn St. Louis Convention Center
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Hilton Pennywell St. Louis at the Arch
Hilton Pennywell St. Louis at the Arch
La Quinta Inn & Suites by Wyndham St Louis Route 66
La Quinta Inn & Suites by Wyndham St Louis Route 66
Casino Queen Hotel
Casino Queen Hotel
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Best Western Plus Fenton
Best Western Plus Fenton
Courtyard by Marriott St. Louis Brentwood
Courtyard by Marriott St. Louis Brentwood
The Cheshire
The Cheshire
Best Western St. Louis-Kirkwood Route 66
Best Western St. Louis-Kirkwood Route 66
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Hampton Inn St. Charles St. Peters
Hampton Inn St. Charles St. Peters
Tru by Hilton St. Charles St. Louis, MO
Tru by Hilton St. Charles St. Louis, MO
Holiday Inn Express Troy by IHG
Holiday Inn Express Troy by IHG
Drury Plaza Hotel St. Louis at the Arch
Drury Plaza Hotel St. Louis at the ArchWhere to stay in Penrose

Downtown St. Louis
Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Busch Stadium – discover Downtown St. Louis, a destination also famous for its historic sites.
Berkeley
Visitors highly recommend Berkeley for its abundant dining options, and you can make a stop by James S. McDonnell Prologue Room while you're in town.

Clayton
Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

Central West End
Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

Downtown West
While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.
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