The Best Hotels in Penrose, St. Louis - 2026 Updated Prices

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Our top choices for Penrose hotels

An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

1. Hampton Inn & Suites St. Louis at Forest Park

Dogtown, 6.5 km from Penrose

Greg

฿5,378 total

includes taxes & fees

1 Oct - 2 Oct

A rooftop terrace with wicker furniture, offering a city view.

2. Drury Plaza Hotel St. Louis at the Arch

Downtown St. Louis, 7.3 km from Penrose

Salvatore

฿5,194 total

includes taxes & fees

4 Oct - 5 Oct

An indoor pool area with a hot tub, seating, and a stone wall.

3. Drury Plaza Hotel St. Louis Union Station

Downtown West, 6.1 km from Penrose

Katy

฿5,283 total

includes taxes & fees

14 Sept - 15 Sept

A multi-story hotel with a prominent corner location, large windows, and a well-lit facade.

4. Embassy Suites by Hilton St. Louis Downtown

Downtown St. Louis, 6.7 km from Penrose

Eloise

฿4,490 total

includes taxes & fees

11 Oct - 12 Oct

A modern bar area with a wooden bar counter, black bar stools, and a large wall with city names.

5. Fairfield Inn & Suites by Marriott St. Louis Downtown

Downtown West, 5.8 km from Penrose

Erik

฿4,904 total

includes taxes & fees

4 Oct - 5 Oct

A rooftop terrace with outdoor seating, string lights, and a city skyline view.

6. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

4.4 km from Penrose

Arturo

฿4,900 total

includes taxes & fees

2 Oct - 3 Oct

A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.

7. Hyatt Select St. Louis Airport

12 km from Penrose

Paige

฿4,451 total

includes taxes & fees

27 Sept - 28 Sept

A lobby with a sofa, two armchairs, a coffee table, and a staircase.

8. Hyatt Regency St. Louis at The Arch

Downtown St. Louis, 7.3 km from Penrose

TRACY

฿5,902 total

includes taxes & fees

4 Oct - 5 Oct

An outdoor seating area with a fire pit, cushioned benches, and a covered patio with string lights.

9. Home2 Suites by Hilton St. Louis/Forest Park

The Grove, 5.5 km from Penrose

paullita jeanne

฿5,982 total

includes taxes & fees

27 Sept - 28 Sept

A modern outdoor lounge area with seating, a bar, and a view of a cityscape.

10. Live by Loews - St.Louis

Downtown St. Louis, 7.2 km from Penrose

Royce

฿6,222 total

includes taxes & fees

13 Sept - 14 Sept

An indoor swimming pool with clear glass ceilings, large windows, and a sunlit area with umbrellas.

11. Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Downtown St. Louis, 7 km from Penrose

Crystal

฿4,701 total

includes taxes & fees

20 Sept - 21 Sept

A snack kiosk with a variety of packaged foods and beverages, a cash register, and a sign reading 'The Shop.'

12. Hilton Garden Inn St. Louis Airport

Berkeley, 8.6 km from Penrose

Darryl

฿5,419 total

includes taxes & fees

13 Sept - 14 Sept

A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

13. Pear Tree Inn St. Louis Airport

13.3 km from Penrose

Monica

฿3,486 total

includes taxes & fees

15 Sept - 16 Sept

A multi-level hotel lobby with seating areas, a reception desk, and large windows offering views.

14. Drury Inn & Suites St. Louis Airport

12.7 km from Penrose

Jeff

฿4,440 total

includes taxes & fees

4 Oct - 5 Oct

A rooftop restaurant with round tables, chairs, and a view of the city.

15. Moonrise Hotel

5.8 km from Penrose

Nicole

฿5,841 total

includes taxes & fees

14 Sept - 15 Sept

An outdoor dining area with a table and chairs, a neon sign, and a glass railing overlooking a cityscape.

16. Aloft by Marriott St Louis Central West End

Central West End, 4.8 km from Penrose

Changsuk

฿4,382 total

includes taxes & fees

20 Sept - 21 Sept

A modern hotel room with a large bed, a desk with a chair, a blue armchair, a sofa, a TV, and a large window offering a city view.

17. DoubleTree by Hilton St. Louis Forest Park

Central West End, 4.8 km from Penrose

Kevin

฿6,113 total

includes taxes & fees

11 Oct - 12 Oct

A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

18. Wingate by Wyndham St. Louis Airport

13.3 km from Penrose

Margaret

฿4,347 total

includes taxes & fees

5 Oct - 6 Oct

A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.

19. The Royal Sonesta Chase Park Plaza St. Louis

Central West End, 4.4 km from Penrose

Lyn

฿7,218 total

includes taxes & fees

4 Oct - 5 Oct

A modern hotel lobby with a reception desk, seating area, and a refreshment bar.

20. SpringHill Suites St. Louis Brentwood

10.4 km from Penrose

Cheryl

฿4,581 total

includes taxes & fees

27 Sept - 28 Sept

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Where to stay in Penrose

Find the best Penrose areas for the activities you enjoy most.

The Gateway Arch in St. Louis, Missouri, with a well-maintained lawn and trees in the foreground.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

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A gazebo by a calm pond with autumn foliage and clear skies.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

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A street corner with a 'Drunken Fish' sushi restaurant and a 'Culpeppers' grill and bar.

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

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A lake with a curved shoreline, a parking lot, and a forested area with autumn foliage.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Skip Viragh Center for the Arts while you're in town.

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A wooden bridge with metal trusses, surrounded by trees.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

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Top Penrose Hotel Reviews

Hyatt Regency St. Louis at The Arch

8/10 Good

"The valet service was fine. It’s supposed to be a “full service” hotel, one would expect higher end amenities but there plastic cups in the room and when we asked the bar for real glasses, it wasn’t permitted. We asked guest service and thank you Talia, the housekeeper for finding glasses for us."

Hollywood Casino & Hotel St. Louis

8/10 Good

"Very nice hotel/casino with an outstanding amphitheatre for major concerts. The restaurant we chose was just OK. The various amenities are nice but extremely pricey. Definitely give the shuttle services 5 stars between the hotel and the amphitheatre. Room was clean except for some trash left under the sink. Beds comfy. Fridge in room didn’t work."

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

8/10 Good

"I have stayed at this hotel a few times. The value is good - a better than expected hotel for the price. There were 2 issues for this last stay. I had a room with an adjacent wall to the elevator area, and the elevator is very loud and clunky when the door opens and shuts. I could hear it all day and all night long (good thing I had good earplugs). Make sure to get a room away from the elevator. Also, the cable tv system is a mess. The channels don't match what the cable guide on the TV says nor what the icon in the corner of the screen says. Also, many of the channels they're supposed to have say "no signal." Not a huge deal but definitely annoying. A simple piece of paper in the room which lists the real channels would certainly help."

Frequently asked questions

What's it like in Penrose?

Travellers are sure to enjoy a stay in St. Louis's Penrose neighbourhood. Consider a visit to Julia Davis Branch Library as part of your Penrose travel plans.

If I need to cancel my hotel reservation in Penrose, will I receive a refund?

Yes! The majority of room reservations are refundable if you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If your reservation is non-refundable, you might still have the option to cancel and receive a refund within 24 hours of your booking. Put your dates in and click on "Search", then filter by "fully refundable" to get top deals in Penrose.

What is there to do around this St. Louis neighbourhood?

Julia Davis Branch Library is an attraction you might want to check out while you're in Penrose. Shelley House and Bellefontaine Cemetery are also worth a visit when you're out sightseeing in St. Louis.

Search Hotels in Penrose, St. Louis

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Our top choices for Penrose hotels

1. Hampton Inn & Suites St. Louis at Forest Park

2. Drury Plaza Hotel St. Louis at the Arch

3. Drury Plaza Hotel St. Louis Union Station

4. Embassy Suites by Hilton St. Louis Downtown

5. Fairfield Inn & Suites by Marriott St. Louis Downtown

6. Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

7. Hyatt Select St. Louis Airport

8. Hyatt Regency St. Louis at The Arch

9. Home2 Suites by Hilton St. Louis/Forest Park

10. Live by Loews - St.Louis

11. Hampton Inn St. Louis-Downtown (At the Gateway Arch)

12. Hilton Garden Inn St. Louis Airport

13. Pear Tree Inn St. Louis Airport

14. Drury Inn & Suites St. Louis Airport

15. Moonrise Hotel

16. Aloft by Marriott St Louis Central West End

17. DoubleTree by Hilton St. Louis Forest Park

18. Wingate by Wyndham St. Louis Airport

19. The Royal Sonesta Chase Park Plaza St. Louis

20. SpringHill Suites St. Louis Brentwood

Where to stay in Penrose

Downtown St. Louis

Clayton

Central West End

Creve Coeur

St. Charles Historic District

Top Penrose Hotel Reviews

Hyatt Regency St. Louis at The Arch

Frequently asked questions