Search Hotels in Otay Mesa, San Diego
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Our top choices for Otay Mesa hotels
1. Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHG
Holiday Inn Express Hotel & Suites San Diego Otay Mesa by IHGOtay Mesa
8.2 out of 10, Very good, (1,806 reviews)
"Clean rooms, friendly staff stay here every year"
JESUS
The price is ฿4,818
฿5,481 total
includes taxes & fees
27 Aug - 28 Aug
2. Quality Suites San Diego Otay Mesa
Quality Suites San Diego Otay MesaOtay Mesa
7.2 out of 10, Good, (1,014 reviews)
"Very quiet and friendly staff excellent breakfast"
Mia
The price is ฿4,010
฿4,561 total
includes taxes & fees
2 Aug - 3 Aug
3. Ayres Hotel San Diego South - Chula Vista
Ayres Hotel San Diego South - Chula Vista6.5 km from Otay Mesa
9.8 out of 10, Exceptional, (1,087 reviews)
"We really enjoyed the cleanliness and the manager Karen was excellent 😊"
Deniece
The price is ฿6,944
฿7,652 total
includes taxes & fees
16 Aug - 17 Aug
4. Best Western Americana Inn
Best Western Americana Inn8 km from Otay Mesa
8.8 out of 10, Excellent, (1,348 reviews)
"Great stay"
Luis
The price is ฿4,215
฿4,795 total
includes taxes & fees
9 Aug - 10 Aug
5. Comfort Inn Chula Vista San Diego South
Comfort Inn Chula Vista San Diego South13 km from Otay Mesa
8.2 out of 10, Very good, (1,617 reviews)
"Beautiful stay!! Nice, clean, and quiet"
Mycah
The price is ฿3,981
฿4,387 total
includes taxes & fees
23 Aug - 24 Aug
6. Best Western Plus Marina Gateway Hotel
Best Western Plus Marina Gateway Hotel16.9 km from Otay Mesa
9.2 out of 10, Wonderful, (3,951 reviews)
"Nice location and clean hotel."
Abdelghani
The price is ฿6,031
฿6,646 total
includes taxes & fees
28 Jul - 29 Jul
7. La Quinta Inn by Wyndham San Diego Chula Vista
La Quinta Inn by Wyndham San Diego Chula Vista12.9 km from Otay Mesa
8.6 out of 10, Excellent, (1,691 reviews)
"Very nice and clean hotel"
Lidia
The price is ฿4,267
฿4,694 total
includes taxes & fees
16 Aug - 17 Aug
8. Holiday Inn Express San Diego South - Chula Vista by IHG
Holiday Inn Express San Diego South - Chula Vista by IHG14.5 km from Otay Mesa
9.4 out of 10, Exceptional, (1,344 reviews)
"Rooms are clean, friendly staff and wonderful breakfast"
yu
The price is ฿5,025
฿5,528 total
includes taxes & fees
25 Aug - 26 Aug
9. SpringHill Suites by Marriott Chula Vista Eastlake
SpringHill Suites by Marriott Chula Vista Eastlake10.5 km from Otay Mesa
9.6 out of 10, Exceptional, (717 reviews)
"We had a great stay at this beautiful property"
Jeannette
The price is ฿6,926
฿7,632 total
includes taxes & fees
9 Aug - 10 Aug
10. Valli Hi Motel
Valli Hi Motel7.9 km from Otay Mesa
8.2 out of 10, Very good, (1,074 reviews)
"Good stay for the price. The Staff was very friendly and accommodating."
elizabeth E
The price is ฿3,032
฿3,456 total
includes taxes & fees
29 Jul - 30 Jul
11. The Rambler Hotel
The Rambler Hotel14.8 km from Otay Mesa
9.0 out of 10, Wonderful, (2,184 reviews)
"We LOVED our stay"
Juanita
The price is ฿4,515
฿5,224 total
includes taxes & fees
16 Aug - 17 Aug
12. Hercor Hotel - Urban Boutique
Hercor Hotel - Urban Boutique13.6 km from Otay Mesa
8.8 out of 10, Excellent, (1,480 reviews)
"Great hotel,"
Keane
The price is ฿3,684
฿4,060 total
includes taxes & fees
10 Aug - 11 Aug
13. SureStay Hotel by Best Western Chula Vista San Diego Bay
SureStay Hotel by Best Western Chula Vista San Diego Bay14.7 km from Otay Mesa
8.0 out of 10, Very good, (1,792 reviews)
"Very good location and good breakfast included."
UBALDO
The price is ฿2,699
฿2,974 total
includes taxes & fees
18 Aug - 19 Aug
14. Best Western Chula Vista/Otay Valley Hotel
Best Western Chula Vista/Otay Valley Hotel7.1 km from Otay Mesa
8.0 out of 10, Very good, (1,899 reviews)
"It was perfect for what we needed and the breakfast was delicious"
Mercedez
The price is ฿3,981
฿4,387 total
includes taxes & fees
23 Aug - 24 Aug
15. Hotel Palmeras Chula Vista
Hotel Palmeras Chula Vista14.4 km from Otay Mesa
7.2 out of 10, Good, (2,283 reviews)
"Excelente hotel"
ERICK GUADALUPE
The price is ฿2,653
฿2,919 total
includes taxes & fees
2 Aug - 3 Aug
16. Loews Coronado Bay Resort
Loews Coronado Bay Resort17.2 km from Otay Mesa
9.0 out of 10, Wonderful, (1,110 reviews)
"We loved our stay here! Such a great place to stay! Can’t wait to go back!"
Kristine
The price is ฿11,085
฿14,007 total
includes taxes & fees
2 Aug - 3 Aug
17. Best Western Plus La Mesa San Diego
Best Western Plus La Mesa San Diego24.6 km from Otay Mesa
8.4 out of 10, Very good, (1,012 reviews)
"Convenient location. Love the included breakfast"
Miguel IV
The price is ฿5,270
฿5,797 total
includes taxes & fees
2 Aug - 3 Aug
18. Hotel Milagro
Hotel Milagro14.9 km from Otay Mesa
7.6 out of 10, Good, (1,006 reviews)
"Great hotel"
Mary
The price is ฿2,493
฿2,742 total
includes taxes & fees
10 Aug - 11 Aug
19. Hampton Inn & Suites San Diego Airport Liberty Station
Hampton Inn & Suites San Diego Airport Liberty Station29.2 km from Otay Mesa
9.2 out of 10, Wonderful, (1,704 reviews)
"Great clean hotel close to the airport. Would definitely stay again."
Aimee
The price is ฿5,334
฿6,131 total
includes taxes & fees
23 Aug - 24 Aug
20. Lamplighter Inn & Suites at SDSU
Lamplighter Inn & Suites at SDSU24.4 km from Otay Mesa
9.0 out of 10, Wonderful, (1,446 reviews)
"Great stay"
Bernadette
The price is ฿5,804
฿6,544 total
includes taxes & fees
17 Aug - 18 Aug
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Otay Mesa
Find the best Otay Mesa areas for the activities you enjoy most.
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Pacific Beach
Relax in beachside cafés in the morning, surf clean breaks in the afternoon and dance with a youthful club crowd at night at this coastal San Diego strip.
Mission Beach
If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.
Gaslamp Quarter
San Diego’s historic heart has shed its seedy past to emerge as one of the city’s premier dining, shopping and entertainment hubs.
Mission Bay
If you're spending some time in Mission Bay, Mission Bay and Ski Beach are top sights worth seeing.
Top Otay Mesa Hotel Reviews
Gaylord Pacific Resort & Convention Center
10/10 Excellent
