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23 Aug - 24 Aug
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Our top choices for Odessa Regional Medical Center hotels

A modern interior with a high ceiling, exposed beams, and a central staircase. There are seating areas with tables and chairs, and a bar area with a counter.
A modern outdoor seating area with a wooden bar, multiple chairs, and potted plants.
A Marriott hotel with a swimming pool, lounge chairs, and potted plants.
A modern interior with a bar area, seating, and a fireplace.

1. Odessa Marriott Hotel & Conference Center

Odessa Marriott Hotel & Conference Center
0.2 km from Odessa Regional Medical Center
United States
Omar
฿5,521
฿6,349 total
includes taxes & fees
28 Aug - 29 Aug
Odessa Marriott Hotel & Conference Center
An outdoor patio area with stone flooring, tables, and chairs.
A buffet with labeled containers of omelets and other food items.
A modern hotel lobby with seating areas, a bar, and a television screen.
A Holiday Inn Express hotel with a modern design, featuring a covered entrance and multiple floors.

2. Holiday Inn Express & Suites Odessa I-20 by IHG

Holiday Inn Express & Suites Odessa I-20 by IHG
3.1 km from Odessa Regional Medical Center
Canada
Ricky
฿2,842
฿3,306 total
includes taxes & fees
6 Sept - 7 Sept
Holiday Inn Express & Suites Odessa I-20 by IHG
A modern kitchen with a central island, bar stools, and a flat-screen TV mounted on the wall.
A gym with cardio machines, a mirror, and a painting on the wall.
A MainStay Suites hotel with a modern facade, multiple floors, and a covered entrance.
A hotel room with two beds, a desk, a chair, and a small table.

3. MainStay Suites Odessa I-20

MainStay Suites Odessa I-20
3 km from Odessa Regional Medical Center
United States
Alfredo
฿2,452
฿2,820 total
includes taxes & fees
30 Aug - 31 Aug
MainStay Suites Odessa I-20
A hotel room with a coffee machine, a trash bin, a small table with a potted plant, and a view of a staircase leading to an outdoor area.
A modern hotel room with a kitchenette, a large window with a view of the outside, and a small seating area.
A hotel room with two beds, a desk with chairs, a flat-screen TV mounted on the wall, and a window with curtains.
A room with a washing machine, a dryer, and a Coca-Cola refrigerator.

4. Motel 6 Odessa, TX - 2nd Street

Motel 6 Odessa, TX - 2nd Street
1.9 km from Odessa Regional Medical Center
United States
Anna
฿1,960
฿2,254 total
includes taxes & fees
25 Aug - 26 Aug
Motel 6 Odessa, TX - 2nd Street
An indoor swimming pool with a clear blue water, surrounded by a tiled deck and a black metal fence.
A hotel room with two beds, a desk, a chair, a lamp, a TV, and an air conditioning unit.
A room with two red sofas, a coffee table, a TV, and large windows.
A reception area with a marble counter, a potted plant, and artwork on the walls.

5. SureStay Plus Hotel by Best Western Odessa

SureStay Plus Hotel by Best Western Odessa
2.7 km from Odessa Regional Medical Center
United States
Laura
฿2,744
฿3,156 total
includes taxes & fees
24 Aug - 25 Aug
SureStay Plus Hotel by Best Western Odessa
A hotel room with two beds, a desk, a chair, a heater, and two framed pictures on the walls.
A covered corridor with doors, a parking area, and a clear sky.
A corridor with fire extinguishers on the wall, windows, and a covered walkway.
A living room with a sofa, a coffee table, and a vase of flowers.

6. Villa West Inn

Villa West Inn
2.6 km from Odessa Regional Medical Center
United States
Timothy
฿2,009
฿2,311 total
includes taxes & fees
24 Aug - 25 Aug
Villa West Inn
A motel with a covered parking area, multiple rooms, and a small commercial space.

7. Deluxe Inn By Capital O Odessa I-20

Deluxe Inn By Capital O Odessa I-20
2.5 km from Odessa Regional Medical Center
United States
Paul
฿1,572
฿1,808 total
includes taxes & fees
24 Aug - 25 Aug
Deluxe Inn By Capital O Odessa I-20
A hotel room with two single beds, each with a patterned bedspread and white pillows. There is a nightstand with a lamp between the beds.
A compact kitchenette with a microwave, refrigerator, and a small sink. A flat-screen TV is mounted on the wall above a wooden desk with a chair.
A compact hotel room with a washing machine, dryer, and a vending machine.
A room with a coffee machine, a sign about morning charge, and a poster on the wall.

8. Motel 6 Odessa, TX

Motel 6 Odessa, TX
2.9 km from Odessa Regional Medical Center
United States
Paul
฿1,640
฿1,886 total
includes taxes & fees
6 Sept - 7 Sept
Motel 6 Odessa, TX
A Courtyard Marriott hotel with a stone facade, multiple windows, and a flagpole.
A hotel lobby with a bar area, seating, and a digital screen displaying news.
A hotel lobby with a bar area, seating arrangements, and a large screen displaying information.
An outdoor patio area with a stone fireplace, seating, and a view of the sky.

9. Courtyard Odessa

Courtyard Odessa
8.6 km from Odessa Regional Medical Center
United States
YuChin
฿2,749
฿3,217 total
includes taxes & fees
4 Sept - 5 Sept
Courtyard Odessa
A hotel pool with lounge chairs and a sign warning against diving.
A modern hotel with a yellow facade, multiple windows, and a covered entrance with flags.
A hotel lobby with a sofa, two bar stools, a fireplace, a television, and a coffee station.
A compact hotel room with a kitchenette, a flat-screen TV, a sofa, and a dining area.

10. Homewood Suites by Hilton Odessa

Homewood Suites by Hilton Odessa
8.6 km from Odessa Regional Medical Center
United States
Melisa
฿2,652
฿3,073 total
includes taxes & fees
4 Sept - 5 Sept
Homewood Suites by Hilton Odessa
An outdoor patio with stone flooring, a fire pit, and wicker chairs.
A swimming pool with lounge chairs and a covered seating area.
A hotel with a covered entrance, multiple flags, and a well-lit facade.
A hotel room with a bed, a desk with a chair, a television, and a sofa.

11. Residence Inn Odessa

Residence Inn Odessa
9.5 km from Odessa Regional Medical Center
United States
Donna
฿2,842
฿3,326 total
includes taxes & fees
5 Sept - 6 Sept
Residence Inn Odessa
A spacious living area with a sofa, chairs, and a coffee table. There is a kitchen area with a counter and appliances in the background.
A hotel lobby with multiple seating areas, a coffee station, and a reception desk.
A hotel room with a bed, a sofa, a desk with a chair, a TV, and a lamp.
A multi-story hotel with a modern design, featuring a prominent 'Best Western PLUS' sign.

12. Best Western Plus North Odessa Inn & Suites

Best Western Plus North Odessa Inn & Suites
8.6 km from Odessa Regional Medical Center
United States
Joao
฿3,134
฿3,604 total
includes taxes & fees
30 Aug - 31 Aug
Best Western Plus North Odessa Inn & Suites
A hotel room with a large sliding glass door leading to a balcony, a bed with a blue and white patterned rug, a small table with a potted plant, and a brick wall.
A modern hotel room with a large bed, a desk, a chair, and a view of the outdoors.
A hot tub with a brick surround, a swimming pool, lounge chairs, and umbrellas.
A hotel with a prominent 'Eleganté' sign, a parking lot, and a well-maintained lawn.

13. MCM Elegante Hotel and Conference Center Odessa

MCM Elegante Hotel and Conference Center Odessa
6 km from Odessa Regional Medical Center
United States
Jill
฿3,079
฿3,541 total
includes taxes & fees
30 Aug - 31 Aug
MCM Elegante Hotel and Conference Center Odessa
An outdoor seating area with colorful striped sofas and chairs, a central fire feature, and a covered patio with wooden ceiling and glass doors.
A hotel reception area with a modern design, featuring a reception desk, a digital kiosk, a minibar, and a self-service beverage station.
A hotel room with a sofa, a bedside table with a lamp, a bed, and a wall-mounted telephone.
A modern hotel with a covered entrance, a fire lane, and a landscaped area with shrubs.

14. Home2 Suites by Hilton Odessa

Home2 Suites by Hilton Odessa
8.3 km from Odessa Regional Medical Center
United States
Emilio
฿3,617
฿4,159 total
includes taxes & fees
30 Aug - 31 Aug
Home2 Suites by Hilton Odessa
An outdoor patio with wicker furniture, a stone fireplace, and a grill.
A man working at a desk with a computer, a woman in a red dress seated at a table in the background, and a framed picture on the wall.
A modern kitchen with a central island, wooden cabinetry, and pendant lighting.
A multi-story hotel with a stone facade, a covered entrance, and multiple windows.

15. Staybridge Suites Odessa - Interstate HWY 20 by IHG

Staybridge Suites Odessa - Interstate HWY 20 by IHG
4.5 km from Odessa Regional Medical Center
United States
Rafael
฿3,365
฿3,870 total
includes taxes & fees
4 Sept - 5 Sept
Staybridge Suites Odessa - Interstate HWY 20 by IHG
An outdoor barbecue area with a grill, seating, and string lights.
A pool area with lounge chairs and a building with multiple windows and a red roof.
A spacious lobby with a fireplace, blue seating, a wooden reception desk, and a bookshelf.
A hotel room with a large bed, a desk, a chair, a sofa, and a TV.

16. TownePlace Suites by Marriott Odessa

TownePlace Suites by Marriott Odessa
5.6 km from Odessa Regional Medical Center
United States
Kenneth
฿3,038
฿3,494 total
includes taxes & fees
3 Sept - 4 Sept
TownePlace Suites by Marriott Odessa
A modern dining area with a long table and chairs, a coffee station, and a large window providing a view of the outdoors.
A modern interior with a market area, seating, and a counter.
A modern hotel building with a prominent 'avid' sign, large windows, and a covered outdoor seating area.
A modern hotel lobby with a reception desk, seating area, and a kitchen in the background.

17. avid hotel Odessa Northwest by IHG

avid hotel Odessa Northwest by IHG
11.2 km from Odessa Regional Medical Center
United States
Cecilia
฿2,744
฿3,128 total
includes taxes & fees
20 Sept - 21 Sept
avid hotel Odessa Northwest by IHG
A Holiday Inn hotel with a covered entrance, stone facade, and multiple windows.
A modern lobby with a sofa, chairs, a coffee table, and a bookshelf.
A spacious lobby with a reception desk, seating area, and a staircase.
A buffet area with various food stations, including a hot foods section and a bakery.

18. Holiday Inn Odessa by IHG

Holiday Inn Odessa by IHG
6.4 km from Odessa Regional Medical Center
Canada
Donald
฿2,875
฿3,349 total
includes taxes & fees
29 Aug - 30 Aug
Holiday Inn Odessa by IHG
A covered outdoor seating area with tables and chairs, wooden beams, and a view of the building in the background.
An indoor swimming pool with clear glass walls, surrounded by white chairs and tables, and a wooden ceiling.

19. MCM Grande Hotel FunDome Odessa

MCM Grande Hotel FunDome Odessa
6.4 km from Odessa Regional Medical Center
United States
Amanda
฿2,355
฿2,708 total
includes taxes & fees
30 Aug - 31 Aug
MCM Grande Hotel FunDome Odessa
A modern living room with a sectional sofa, a fireplace, and a mounted TV.
A hotel lobby with a reception desk, seating area, and a television mounted on the wall.
A gym with exercise equipment, a bench, and a TV on the wall.
A spacious living area with a fireplace, a dining table with chairs, and a television mounted on the wall.

20. Baymont by Wyndham Odessa

Baymont by Wyndham Odessa
9.2 km from Odessa Regional Medical Center
Canada
Ricky
฿2,132
฿2,452 total
includes taxes & fees
30 Aug - 31 Aug
Baymont by Wyndham Odessa
View all properties

Compare popular hotels close to Odessa Regional Medical Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A modern interior with a high ceiling, exposed beams, and a central staircase. There are seating areas with tables and chairs, and a bar area with a counter.
Odessa Marriott Hotel & Conference Center
9.2
Wonderful
540 reviews
View
An outdoor patio area with stone flooring, tables, and chairs.
Holiday Inn Express & Suites Odessa I-20 by IHG
8.8
Excellent
548 reviews
View
A modern kitchen with a central island, bar stools, and a flat-screen TV mounted on the wall.
MainStay Suites Odessa I-20
8.2
Very good
332 reviews
View
A hotel room with a coffee machine, a trash bin, a small table with a potted plant, and a view of a staircase leading to an outdoor area.
Motel 6 Odessa, TX - 2nd Street
7.8
Good
566 reviews
View
An indoor swimming pool with a clear blue water, surrounded by a tiled deck and a black metal fence.
SureStay Plus Hotel by Best Western Odessa
7.4
Good
101 reviews
View

Top Odessa Regional Medical Center Hotel Reviews

Howard Johnson by Wyndham Odessa TX

Howard Johnson by Wyndham Odessa TX

10/10 Excellent
"Nice place good rooms"
April 1-night trip
Posted 22 hours ago
Howard Johnson by Wyndham Odessa TX
MCM Grande Hotel FunDome Odessa

MCM Grande Hotel FunDome Odessa

10/10 Excellent
"."
Karina 2-night trip
Posted 1 day ago
MCM Grande Hotel FunDome Odessa
Holiday Inn Express & Suites Odessa I-20 by IHG

Holiday Inn Express & Suites Odessa I-20 by IHG

8/10 Good
"Very clean"
Crystal 2-night trip
Posted 6 days ago
Holiday Inn Express & Suites Odessa I-20 by IHG
La Quinta Inn by Wyndham Odessa

La Quinta Inn by Wyndham Odessa

10/10 Excellent
"The room was clean and comfortable!"
Kaitlin 1-night trip
Posted 9 days ago
La Quinta Inn by Wyndham Odessa
Motel 6 Odessa, TX - 2nd Street

Motel 6 Odessa, TX - 2nd Street

10/10 Excellent
"Decent"
Jonathan 6-night trip
Posted 2 months ago
Motel 6 Odessa, TX - 2nd Street

Frequently asked questions

What's the area like around Odessa Regional Medical Center?
Odessa Regional Medical Center is located in Odessa. This family-friendly area is known for its array of dining options. If you're looking for a convenient place to stay, take a look at the 9 hotels and other accommodation options you'll find within a mile.
What's the best place to stay close to Odessa Regional Medical Center?
Adjacent to Odessa Regional Medical Center, Odessa Marriott Hotel & Conference Center is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. Other good choices within a few miles include MCM Grande Hotel FunDome Odessa and Motel 6 Odessa, TX - 2nd Street.
How many hotels can I expect to find near Odessa Regional Medical Center?
Expedia has 9 hotels and other accommodation options within a mile from Odessa Regional Medical Center.
If I need to cancel the hotel reservation for my stay near Odessa Regional Medical Center, will I receive a refund?
Yes! The majority of hotel bookings are fully refundable if you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Put your dates in and click on "Search", then use the "fully refundable" filter to review the best deals near Odessa Regional Medical Center.
What can I see and do near Odessa Regional Medical Center?
Study the collections at White-Pool House, Ellen Noel Art Museum or Parker House Museum. Create some family memories at Altitude Trampoline Park and Fun City. Attractions like Globe of the Great Southwest and Presidential Museum and Leadership Library highlight the local culture.