Find hotels in O Brien, FL from ฿1,934

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Top 10 O Brien hotels and places to stay

Hampton Inn & Suites Lake City

2.5 star property
9.4 out of 10, Exceptional, (998)
"Nice stay"
The price is ฿3,178
฿3,575 total
includes taxes & fees
4 Aug - 5 Aug
Hampton Inn & Suites Lake City

Americas Best Value Inn Lake City

2.0 star property
8.8 out of 10, Excellent, (1003)
"I have been going here on and off for 10 years to see my kids and grandkids. The staff and management are friendly. "
The price is ฿2,311
฿2,600 total
includes taxes & fees
12 Aug - 13 Aug
Americas Best Value Inn Lake City

Tru by Hilton Lake City

2.5 star property
9.2 out of 10, Wonderful, (1002)
"The hotel was very clean, the staff as friendly and helpful and the bed was soooo comfortable!"
The price is ฿2,787
฿3,135 total
includes taxes & fees
5 Aug - 6 Aug
Tru by Hilton Lake City

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

3.5 star property
9.4 out of 10, Exceptional, (1002)
"Really enjoyed our stay! "
The price is ฿3,673
฿4,132 total
includes taxes & fees
24 Aug - 25 Aug
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Home2 Suites by Hilton Lake City

3.0 star property
9.4 out of 10, Exceptional, (693)
"The hotel was very clean and updated. Would definitely recommend and stay here again. "
The price is ฿3,636
฿4,091 total
includes taxes & fees
31 Aug - 1 Sept
Home2 Suites by Hilton Lake City

The Blanche

2.0 star property
9.2 out of 10, Wonderful, (142)
"Beautiful hotel! Elegant, classy. Loved it! "
The Blanche

Postcard Cabins Gilchrist Springs

2.0 star property
10.0 out of 10, Exceptional, (63)
"the cabin was amazing, great amenities i would recommend!!"
The price is ฿3,868
฿5,507 total
includes taxes & fees
3 Aug - 4 Aug
Postcard Cabins Gilchrist Springs

Fairfield Inn & Suites Lake City

2.5 star property
9.0 out of 10, Wonderful, (116)
"The staff was friendly and helpful."
The price is ฿2,735
฿3,077 total
includes taxes & fees
7 Aug - 8 Aug
Fairfield Inn & Suites Lake City

Comfort Suites Lake City

2.5 star property
9.6 out of 10, Exceptional, (1001)
"Friendly staff great breakfast "
The price is ฿3,230
฿3,634 total
includes taxes & fees
24 Aug - 25 Aug
Comfort Suites Lake City

Best Western Plus Lake City

2.5 star property
9.2 out of 10, Wonderful, (1000)
"Room was clean, breakfast was good, and staff was very pleasant. "
The price is ฿2,764
฿3,110 total
includes taxes & fees
10 Aug - 11 Aug
Best Western Plus Lake City

La Quinta Inn & Suite by Wyndham Lake City

2.5 star property
8.8 out of 10, Excellent, (1000)
"Clean modern hotel and served our purpose."
The price is ฿3,066
฿3,449 total
includes taxes & fees
4 Aug - 5 Aug
La Quinta Inn & Suite by Wyndham Lake City

Vista Verde Farm Retreat

2.0 star property
9.8 out of 10, Exceptional, (6)
"This is my second time staying on this property and I love it "
The price is ฿3,576
฿6,254 total
includes taxes & fees
1 Sept - 2 Sept
Vista Verde Farm Retreat

Super 8 by Wyndham Lake City

2.0 star property
7.2 out of 10, Good, (631)
"Good breakfast nice pool and a great price "
The price is ฿2,156
฿2,425 total
includes taxes & fees
5 Aug - 6 Aug
Super 8 by Wyndham Lake City

Palms Garden Inn

2.0 star property
7.4 out of 10, Good, (550)
"We stayed for 1 night on a long trip, and it was comfortable and dog friendly with a nice big area to run around with the dog. We would definitely stay again."
The price is ฿2,176
฿2,448 total
includes taxes & fees
5 Aug - 6 Aug
Palms Garden Inn

Days Inn by Wyndham Lake City I-75

2.0 star property
7.4 out of 10, Good, (1002)
"Nice, clean comfortable place to sleep for a decent price"
The price is ฿2,183
฿2,456 total
includes taxes & fees
5 Aug - 6 Aug
Days Inn by Wyndham Lake City I-75

BlueGem Motel

2.0 star property
9.2 out of 10, Wonderful, (361)
"Amazing owners"
The price is ฿3,154
฿3,548 total
includes taxes & fees
3 Aug - 4 Aug
BlueGem Motel

Quality Inn Lake City

2.5 star property
7.8 out of 10, Good, (912)
"Great location right off the interstate"
The price is ฿2,473
฿2,782 total
includes taxes & fees
31 Aug - 1 Sept
Quality Inn Lake City

Days Inn by Wyndham Lake City I-10

2.0 star property
6.8 out of 10, (1000)
"It s a very nice hotel"
The price is ฿2,210
฿2,487 total
includes taxes & fees
12 Aug - 13 Aug
Days Inn by Wyndham Lake City I-10

Regal Inn

2.5 star property
8.6 out of 10, Excellent, (517)
"Great staff great stay"
The price is ฿2,017
฿2,269 total
includes taxes & fees
12 Aug - 13 Aug
Regal Inn

Driftwood Inn

2.0 star property
7.8 out of 10, Good, (739)
"Review"
Driftwood Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about O Brien

Explore attractions like Suwannee River and Ichetucknee River as you discover things to see and do in O Brien.

Photo by Dr__Vlad
Open Photo by Dr__Vlad

Top O Brien Hotel Reviews

Frequently asked questions

Where is the best place to stay in O Brien?

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG, located 29.9 mi (48.2 km) from the heart of O Brien, is a top choice for your stay, based on our traveller data. Two other options for your trip to the area are La Quinta Inn & Suite by Wyndham Lake City and Best Western Plus Lake City. See all available top hotels, or vacation rentals in O Brien.

If I need to cancel my hotel reservation in O Brien, will I receive a refund?

Yes! You'll find that most hotel bookings are refundable if you cancel before the hotel’s cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in O Brien.

What are some accommodation options with pools in O Brien?

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG: Provides buffet, an outdoor pool and complimentary high-speed (wired) Internet access. La Quinta Inn & Suite by Wyndham Lake City and Best Western Plus Lake City are two additional hotels that feature an on-site pool. View all hotels with pools in O Brien.

How is it to stay in O Brien?

Visitors to O Brien will definitely find plenty to explore and enjoy. In O Brien, there are 10 hotels and other accommodation options to choose from. Find out more about O Brien.

What are the top places to visit in O Brien?

Natural beauty is on display at Suwannee River, Ichetucknee River and Ichetucknee Springs State Park. You'll also find Troy Spring State Park and Wes Skiles Peacock Springs State Park in the area. Take a look at what more there is to see and do in Expedia's O Brien guide.

What's the seasonal weather in O Brien?

The hottest months are usually July and August, with an average temperature of 27°C, while the coldest months are January and February, with an average of 14°C. Average annual precipitation for O Brien is 1278 mm.