Find hotels in O Brien, FL from ฿1,357

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Our top choices for O Brien hotels

Hampton Inn & Suites Alachua I-75

Hampton Inn & Suites Alachua I-75
2.5 star property
Alachua
9.4 out of 10, Exceptional, (479 reviews)
"Good overnight experience on a car trip. Nice staff."
United States
Luis
The price is ฿3,267
฿3,675 total
includes taxes & fees
1 Feb - 2 Feb
Hampton Inn & Suites Alachua I-75

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
2.0 star property
High Springs
10.0 out of 10, Exceptional, (164 reviews)
"Fantastic place! Very nice amenities and service was wonderful"
United States
Annette
The price is ฿3,106
฿6,177 total
includes taxes & fees
13 Jan - 14 Jan
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
3.5 star property
Alachua
9.4 out of 10, Exceptional, (1,008 reviews)
"Great stay. Good breakfast. "
United States
Bob
The price is ฿3,671
฿4,129 total
includes taxes & fees
18 Jan - 19 Jan
Holiday Inn Express & Suites Alachua - Gainesville Area by IHG

Quality Inn White Springs Suwanee

Quality Inn White Springs Suwanee
2.5 star property
Live Oak
7.2 out of 10, Good, (626 reviews)
"Clean rooms, very friendly staff"
United States
Kristin L
The price is ฿1,931
฿2,124 total
includes taxes & fees
26 Jan - 27 Jan
Quality Inn White Springs Suwanee

La Quinta Inn & Suite by Wyndham Lake City

La Quinta Inn & Suite by Wyndham Lake City
2.5 star property
Lake City
8.8 out of 10, Excellent, (1,037 reviews)
"Room was clean and all the staff were very nice."
United States
Wayne
The price is ฿2,965
฿3,335 total
includes taxes & fees
18 Jan - 19 Jan
La Quinta Inn & Suite by Wyndham Lake City

Super 8 by Wyndham Lake City

Super 8 by Wyndham Lake City
2.0 star property
Lake City
7.2 out of 10, Good, (673 reviews)
"Clean room, friendly staff, fantastic food!"
United States
John
The price is ฿2,080
฿2,340 total
includes taxes & fees
14 Jan - 15 Jan
Super 8 by Wyndham Lake City

Courtyard By Marriott Lake City

Courtyard By Marriott Lake City
3.0 star property
Lake City
9.6 out of 10, Exceptional, (187 reviews)
"The best part of this stay was a room with 2 king beds!!!!! Property was in excellent condition and front desk person was super. Highly recommend."
United States
Joyce
The price is ฿3,357
฿3,776 total
includes taxes & fees
18 Jan - 19 Jan
Courtyard By Marriott Lake City

Tru by Hilton Lake City

Tru by Hilton Lake City
2.5 star property
Lake City
9.2 out of 10, Wonderful, (1,007 reviews)
"Very clean and nice staff "
United States
renae
The price is ฿3,146
฿3,539 total
includes taxes & fees
18 Jan - 19 Jan
Tru by Hilton Lake City

Comfort Suites Lake City

Comfort Suites Lake City
2.5 star property
Lake City
9.6 out of 10, Exceptional, (1,000 reviews)
"Clean room, great breakfast and staff super friendly "
United States
Gary
The price is ฿3,360
฿3,780 total
includes taxes & fees
18 Jan - 19 Jan
Comfort Suites Lake City

Fairfield Inn & Suites Lake City

Fairfield Inn & Suites Lake City
2.5 star property
Lake City
9.0 out of 10, Wonderful, (179 reviews)
"Very clean, friendly staff, safe and quiet "
United States
Amy
The price is ฿3,074
฿3,459 total
includes taxes & fees
18 Jan - 19 Jan
Fairfield Inn & Suites Lake City

Americas Best Value Inn Lake City

Americas Best Value Inn Lake City
2.0 star property
Lake City
8.8 out of 10, Excellent, (1,005 reviews)
"Nice quiet and comfortable hotel a little gem."
Canada
Tim
The price is ฿2,107
฿2,370 total
includes taxes & fees
13 Jan - 14 Jan
Americas Best Value Inn Lake City

Hampton Inn & Suites Lake City

Hampton Inn & Suites Lake City
2.5 star property
Lake City
9.4 out of 10, Exceptional, (1,005 reviews)
"Excellent staff and clean organized room"
United States
Robert
The price is ฿3,576
฿4,023 total
includes taxes & fees
18 Jan - 19 Jan
Hampton Inn & Suites Lake City

Days Inn by Wyndham Lake City I-75

Days Inn by Wyndham Lake City I-75
2.0 star property
Lake City
7.6 out of 10, Good, (1,001 reviews)
"Staff was great"
United States
Thomas
The price is ฿1,983
฿2,231 total
includes taxes & fees
13 Jan - 14 Jan
Days Inn by Wyndham Lake City I-75

Best Western Plus Lake City

Best Western Plus Lake City
2.5 star property
Lake City
9.0 out of 10, Wonderful, (1,045 reviews)
"Great place to stay"
United States
Jack
The price is ฿3,137
฿3,529 total
includes taxes & fees
18 Jan - 19 Jan
Best Western Plus Lake City

Regal Inn

Regal Inn
2.5 star property
Lake City
8.6 out of 10, Excellent, (548 reviews)
"Comfortable bed, roomy bathroom. Negative:barn door separating bedroom & bathroom (affects privacy), no clothes hangers. "
United States
Linda
The price is ฿1,946
฿2,189 total
includes taxes & fees
13 Jan - 14 Jan
Regal Inn

Palms Garden Inn

Palms Garden Inn
2.0 star property
Lake City
7.4 out of 10, Good, (583 reviews)
"Clean and nice staff "
United States
apollo
The price is ฿2,038
฿2,292 total
includes taxes & fees
13 Jan - 14 Jan
Palms Garden Inn

The Blanche

The Blanche
2.0 star property
Lake City
9.2 out of 10, Wonderful, (166 reviews)
"Easy to access building and room with code provided; amazing bed and very clean."
United States
Ruth
The Blanche

BlueGem Motel

BlueGem Motel
2.0 star property
High Springs
9.2 out of 10, Wonderful, (400 reviews)
"Beautiful room, very clean and the bed was incredibly soft and comfortable to sleep in! "
United States
Julians
The price is ฿2,800
฿3,150 total
includes taxes & fees
13 Jan - 14 Jan
BlueGem Motel

Holiday Inn & Suites Lake City by IHG

Holiday Inn & Suites Lake City by IHG
3.0 star property
Lake City
8.6 out of 10, Excellent, (1,003 reviews)
"Great place"
United States
John
The price is ฿2,729
฿3,071 total
includes taxes & fees
18 Jan - 19 Jan
Holiday Inn & Suites Lake City by IHG

Quality Inn Lake City

Quality Inn Lake City
2.5 star property
Lake City
7.8 out of 10, Good, (959 reviews)
"Room clean and nice. Quiet location with many choices for food"
United States
Dennis
The price is ฿2,235
฿2,514 total
includes taxes & fees
10 Feb - 11 Feb
Quality Inn Lake City
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Learn more about O Brien

Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

kayakers at Rock Bluff Spring on the Suwanneee River, Gilchrist County, Florida

Top O Brien Hotel Reviews

More cheap stays in O Brien

Frequently asked questions

Where is the best place to stay in O Brien?
La Quinta Inn & Suite by Wyndham Lake City, located 18.2 mi (29.3 km) from the heart of O Brien, is a top choice for your stay, based on our traveller data. Two other options for your trip to the area are Tru by Hilton Lake City and Holiday Inn Express & Suites Alachua - Gainesville Area by IHG. See all available top hotels, or vacation rentals in O Brien.
If I need to cancel my hotel reservation in O Brien, will I receive a refund?
Yes! You'll find that most hotel bookings are refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might be able to still cancel and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in O Brien.
What are some accommodation options with pools in O Brien?
La Quinta Inn & Suite by Wyndham Lake City: Provides on-the-go, an indoor pool and free self parking. Tru by Hilton Lake City and Holiday Inn Express & Suites Alachua - Gainesville Area by IHG are two additional hotels that feature an on-site pool. View all hotels with pools in O Brien.
How is it to stay in O Brien?
Visitors to O Brien will definitely find plenty to explore and enjoy. In O Brien, there are 11 hotels and other accommodation options to choose from. Find out more about O Brien.
What are the top places to visit in O Brien?
Natural beauty is on display at Suwannee River, Ichetucknee River and Ichetucknee Springs State Park. You'll also find Wes Skiles Peacock Springs State Park and Lafayette Blue Springs State Park in the area. Take a look at what more there is to see and do in Expedia's O Brien guide.
What's the seasonal weather in O Brien?
The hottest months are usually July and August, with an average temperature of 27°C, while the coldest months are January and February, with an average of 14°C. Average annual precipitation for O Brien is 1278 mm.

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