
Find hotels in O Brien, FL from ฿1,357
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Go beyond your typical stay in O Brien
Family friendly
Check prices for these dates
Our top choices for O Brien hotels

Hampton Inn & Suites Alachua I-75
Hampton Inn & Suites Alachua I-75Alachua
9.4 out of 10, Exceptional, (479 reviews)
The price is ฿3,267
฿3,675 total
includes taxes & fees
1 Feb - 2 Feb

Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott Bonvoy
Postcard Cabins Gilchrist Springs, Outdoor Collection by Marriott BonvoyHigh Springs
10.0 out of 10, Exceptional, (164 reviews)
The price is ฿3,106
฿6,177 total
includes taxes & fees
13 Jan - 14 Jan

Holiday Inn Express & Suites Alachua - Gainesville Area by IHG
Holiday Inn Express & Suites Alachua - Gainesville Area by IHGAlachua
9.4 out of 10, Exceptional, (1,008 reviews)
The price is ฿3,671
฿4,129 total
includes taxes & fees
18 Jan - 19 Jan

Quality Inn White Springs Suwanee
Quality Inn White Springs SuwaneeLive Oak
7.2 out of 10, Good, (626 reviews)
The price is ฿1,931
฿2,124 total
includes taxes & fees
26 Jan - 27 Jan

La Quinta Inn & Suite by Wyndham Lake City
La Quinta Inn & Suite by Wyndham Lake CityLake City
8.8 out of 10, Excellent, (1,037 reviews)
The price is ฿2,965
฿3,335 total
includes taxes & fees
18 Jan - 19 Jan

Super 8 by Wyndham Lake City
Super 8 by Wyndham Lake CityLake City
7.2 out of 10, Good, (673 reviews)
The price is ฿2,080
฿2,340 total
includes taxes & fees
14 Jan - 15 Jan

Courtyard By Marriott Lake City
Courtyard By Marriott Lake CityLake City
9.6 out of 10, Exceptional, (187 reviews)
The price is ฿3,357
฿3,776 total
includes taxes & fees
18 Jan - 19 Jan

Tru by Hilton Lake City
Tru by Hilton Lake CityLake City
9.2 out of 10, Wonderful, (1,007 reviews)
The price is ฿3,146
฿3,539 total
includes taxes & fees
18 Jan - 19 Jan

Comfort Suites Lake City
Comfort Suites Lake CityLake City
9.6 out of 10, Exceptional, (1,000 reviews)
The price is ฿3,360
฿3,780 total
includes taxes & fees
18 Jan - 19 Jan

Fairfield Inn & Suites Lake City
Fairfield Inn & Suites Lake CityLake City
9.0 out of 10, Wonderful, (179 reviews)
The price is ฿3,074
฿3,459 total
includes taxes & fees
18 Jan - 19 Jan

Americas Best Value Inn Lake City
Americas Best Value Inn Lake CityLake City
8.8 out of 10, Excellent, (1,005 reviews)
The price is ฿2,107
฿2,370 total
includes taxes & fees
13 Jan - 14 Jan

Hampton Inn & Suites Lake City
Hampton Inn & Suites Lake CityLake City
9.4 out of 10, Exceptional, (1,005 reviews)
The price is ฿3,576
฿4,023 total
includes taxes & fees
18 Jan - 19 Jan

Days Inn by Wyndham Lake City I-75
Days Inn by Wyndham Lake City I-75Lake City
7.6 out of 10, Good, (1,001 reviews)
The price is ฿1,983
฿2,231 total
includes taxes & fees
13 Jan - 14 Jan

Best Western Plus Lake City
Best Western Plus Lake CityLake City
9.0 out of 10, Wonderful, (1,045 reviews)
The price is ฿3,137
฿3,529 total
includes taxes & fees
18 Jan - 19 Jan

Palms Garden Inn
Palms Garden InnLake City
7.4 out of 10, Good, (583 reviews)
The price is ฿2,038
฿2,292 total
includes taxes & fees
13 Jan - 14 Jan


BlueGem Motel
BlueGem MotelHigh Springs
9.2 out of 10, Wonderful, (400 reviews)
The price is ฿2,800
฿3,150 total
includes taxes & fees
13 Jan - 14 Jan

Holiday Inn & Suites Lake City by IHG
Holiday Inn & Suites Lake City by IHGLake City
8.6 out of 10, Excellent, (1,003 reviews)
The price is ฿2,729
฿3,071 total
includes taxes & fees
18 Jan - 19 Jan

Quality Inn Lake City
Quality Inn Lake CityLake City
7.8 out of 10, Good, (959 reviews)
The price is ฿2,235
฿2,514 total
includes taxes & fees
10 Feb - 11 Feb
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Learn more about O Brien
Escape to this rural Florida gem where the Suwannee River offers peaceful kayaking trips and fishing adventures. Nearby Spirit of the Suwannee Music Park hosts live concerts, while O'Brien's local farms welcome visitors for fresh produce and family-friendly activities.

Top O Brien Hotel Reviews

Courtyard By Marriott Lake City
10/10 Excellent
More cheap stays in O Brien

Motel 6 – Lake City, Fl – Medical Center
3340 W US Highway 90 Lake City FL
The price is ฿2,173 per night from 13 Jan to 14 Jan
฿2,173
฿2,445 total
13 Jan - 14 Jan
includes taxes & fees
8.2/10 Very Good! (92 reviews)




































































