Northeast Missouri Holiday Rentals, Missouri: Private House Rentals

A large eye sculpture in a park surrounded by trees.

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Go beyond your typical stay in Northeast Missouri

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Our top choices for Northeast Missouri hotels

An indoor swimming pool with a view of the outside, a sign reading 'Depot Inn,' and a 'RAILROAD CROSSING' sign on the wall.

A living room with a flat-screen TV, fireplace, and a couch with pillows.

A hotel lobby with a reception desk, a coffee station, and seating areas.

A hotel lobby with a reception desk, seating area, and a sign for the general store.

1. Depot Inn and Suites

La Plata

David

฿3,290

฿3,565 total

includes taxes & fees

30 Aug - 31 Aug

A hotel room with a large bed, a desk with a computer, a television, and a bathtub.

A bar area with a long counter, multiple bottles, glasses, and a few chairs.

A hotel room with a sofa, armchair, small table, TV, dresser, and a bathtub.

A multi-story hotel with a covered entrance and a sign indicating it is part of the Oak Hill Inn & Suites.

2. Oak Hill Inn & Suites

Canton

Candace

฿3,309

฿3,772 total

includes taxes & fees

27 Aug - 28 Aug

An indoor swimming pool with a tiled floor, a rock wall, and a palm tree.

A hotel room with a bed, desk, chair, and a bathroom with a bathtub.

A hotel entrance with a central fountain, large columns, and a clear sky.

A spacious dining area with wooden flooring and tables, surrounded by glass walls and wooden paneling.

3. Quality Inn & Suites Hannibal West

Hannibal

Mohamed

฿2,290

฿2,664 total

includes taxes & fees

30 Aug - 31 Aug

A spacious lobby with a high ceiling, a reception desk, seating areas, and a staircase leading to an upper level.

A hotel room with two beds, a desk, a blue sofa, and a TV.

A Holiday Inn Express hotel with a modern design, featuring a covered entrance and multiple windows.

A modern lobby with a reception desk, seating area, and a dining section.

4. Holiday Inn Express & Suites St Peters by IHG

St. Peters

Serah

฿3,857

฿4,636 total

includes taxes & fees

30 Aug - 31 Aug

A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

A hotel room with a bed, a desk, a television, and a lamp.

A spacious indoor area with multiple wooden tables and chairs, large windows, and a high ceiling with exposed beams.

A spacious indoor area with a high ceiling and large windows, featuring multiple seating areas with sofas and chairs, and a visible outdoor view through the windows.

5. Pear Tree Inn St. Louis Airport

St. Ann

Darren

฿2,942

฿3,463 total

includes taxes & fees

31 Aug - 1 Sept

A hotel room with a large bed, a separate bathroom with a bathtub, and a desk with a chair.

A multi-level indoor pool area with a clear pool, multiple balconies, and a covered seating area.

A multi-level indoor pool area with a visible water slide, a towel rack, and a notice board.

A hotel kitchen with a buffet setup, including a coffee station and various food items.

6. Best Western On The River

Hannibal

Devin S

฿3,922

฿4,524 total

includes taxes & fees

30 Aug - 31 Aug

A Sleep Inn & Suites building with a covered entrance, stone facade, and a flag.

An indoor swimming pool with a lifeguard chair, poolside chairs, and a table with chairs.

A modern lobby with a brown sofa, beige armchairs, a round table, and a floor lamp.

A hotel room with a bed, a desk, a chair, a sofa, and a TV mounted on the wall.

7. Sleep Inn & Suites Hannibal West

Hannibal

Steve

฿3,862

฿4,494 total

includes taxes & fees

20 Sept - 21 Sept

A bathroom with a large bathtub, a chair, and a small shelf with plants.

A hotel room with two beds, wooden flooring, a desk with a chair, a microwave, and a potted plant.

An outdoor seating area with a fire pit, chairs, and two evergreen trees.

8. Pinemark Inn & Suites

St. Clair

David

฿4,395

฿4,811 total

includes taxes & fees

27 Aug - 28 Aug

A modern hotel room with a dining area, wooden cabinets, a checkered floor, and a flat-screen TV.

A lobby with two orange armchairs, a small table, a flat-screen TV, framed pictures, and a wall-mounted shelf with decorative items.

A Wingate hotel with a covered entrance, outdoor seating, and a parking lot.

A hotel room with a desk, chair, TV, and a framed picture on the wall.

9. Wingate by Wyndham St. Louis Airport

St. Ann

Margaret

฿3,677

฿4,330 total

includes taxes & fees

27 Aug - 28 Aug

A spacious living room with a large painting, a fireplace, a staircase, and modern furniture.

A hotel room with a dining area, a fireplace, and a view of the outdoors.

A swimming pool with tiled edges and a hot tub area, surrounded by windows and chairs.

An outdoor patio with a beige sofa set, two armchairs, and a table.

10. Best Western Plus Washington Hotel

Washington

Aaron

฿4,217

฿4,801 total

includes taxes & fees

31 Aug - 1 Sept

A multi-level hotel lobby with seating areas, a reception desk, and large windows offering views.

A pool area with two hot tubs, seating, and a view of the outdoors.

A modern kitchen with a stainless steel range hood, a bar area with stools, and a large window providing a view of the outdoors.

A hotel reception area with a counter, seating, and a staircase.

11. Drury Inn & Suites St. Louis Airport

Edmundson

Robert

฿3,759

฿4,410 total

includes taxes & fees

30 Aug - 31 Aug

A modern living room with a built-in fireplace, a large flat-screen TV, a unique hexagonal pendant light, and a patterned rug.

A modern dining area with a long table, multiple chairs, and a unique chandelier.

A modern lobby with blue seating, a reception desk, and large windows.

A multi-story hotel with a stone facade, a covered entrance, and a parking lot.

12. Hyatt Select St. Louis Airport

Woodson Terrace

Paige

฿3,596

฿4,422 total

includes taxes & fees

20 Sept - 21 Sept

A spacious lobby with a staircase, a blue sofa, and a wooden table.

A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.

A gym with treadmills, weight machines, and a large potted plant.

A modern interior with a large window, a flat-screen TV mounted on a wall, and a seating area with colorful stools.

13. Quality Inn Foristell

Foristell

Rebecca

฿2,677

฿3,024 total

includes taxes & fees

31 Aug - 1 Sept

A buffet with various food items, including omelets and cheese.

14. Holiday Inn Express & Suites Wentzville St Louis West by IHG

Wentzville

Derek

฿4,413

฿5,258 total

includes taxes & fees

30 Aug - 31 Aug

A Comfort Inn hotel with a modern design, featuring a covered entrance and a clear sky in the background.

A modern kitchen with a coffee station, bread display, and a sign that reads "RISE & SHINE".

An indoor swimming pool with clear water, surrounded by stone flooring, and equipped with multiple chairs and a blue lounge chair.

A modern hotel lobby with a sofa, chairs, a coffee table, and a floor lamp.

15. Comfort Inn Sullivan

Sullivan

Kelly

฿4,168

฿4,542 total

includes taxes & fees

20 Sept - 21 Sept

A modern kitchen with a bar area, wooden cabinets, and pendant lighting.

A hotel room with two beds, a sofa, a small table, a lamp, and a framed abstract painting on the wall.

A swimming pool with a tiled deck, a sunlit room with a view, and a seating area with chairs.

A modern hotel entrance with a glass canopy, large windows, and a brick facade.

16. Hyatt Place St. Louis/Chesterfield

Chesterfield

Taylor

฿3,821

฿4,432 total

includes taxes & fees

13 Sept - 14 Sept

A modern interior with hanging pendant lights, large windows, and a view of the outside.

A modern hotel lobby with a high ceiling, multiple hanging pendant lights, a reception desk with a Missouri US 66 sign, and large windows allowing natural light.

A modern hotel with a covered entrance, brick facade, and a parking area.

A hotel indoor pool area with a hot tub, seating, and a view of the outdoors.

17. Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Fenton

LINDSAY

฿3,084

฿3,562 total

includes taxes & fees

27 Aug - 28 Aug

An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

A hotel with a modern design, featuring a large entrance, multiple floors, and a parking lot.

A hotel reception area with a modern design, featuring a reception desk, a wall with a welcome sign, and a view of the lobby.

A spacious room with a long table and chairs, a television mounted on the wall, and a 'Welcome to the Show Nest' sign.

18. Hampton Inn & Suites St. Louis at Forest Park

Dogtown

rodnina

฿4,262

฿5,026 total

includes taxes & fees

1 Sept - 2 Sept

A hotel room with a bed, a sofa, a coffee table, and wall art.

A Sleep Inn & Suites hotel with a modern brick facade, a covered entrance, and a parking lot.

A restaurant with wooden tables and chairs, a blue wall with white floral patterns, and a counter with a coffee machine.

An indoor swimming pool with a clear view of the outside, a metal ladder, and a ceiling with recessed lighting.

19. Sleep Inn & Suites O'Fallon MO - Technology Drive

O'Fallon

Josh

฿2,568

฿3,029 total

includes taxes & fees

15 Sept - 16 Sept

A modern kitchen with a dining area, featuring a kitchen island with appliances and a coffee station.

A kitchenette with a coffee machine, a paper towel dispenser, and a trash bin labeled "THANK YOU".

A modern living room with a stone wall, a flat-screen TV, a built-in fish tank, a blue sofa, and a large window with a view of a parking lot.

A modern hotel lobby with a reception desk, seating area, and large windows.

20. Super 8 by Wyndham Kirksville-University Area

Kirksville

David

฿2,092

฿2,350 total

includes taxes & fees

13 Sept - 14 Sept

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Holiday Rentals in Northeast Missouri

Cabin

A park with a pond, picnic tables, and a gazebo.

A row of rustic, single-story buildings with a grassy lawn and picnic tables.

A small, well-lit kitchen with a dining table, chairs, a refrigerator, a microwave, and a television mounted on the wall.

Cannon Dam Cabins

Perry

"Cozy and well equipped with everything we may have needed"

Aparthotel

A hotel room with a large bed, two bedside lamps, a modern bathroom, and a vibrant abstract painting on the wall.

A swimming pool with lounge chairs and a covered seating area.

A spacious bathroom with a large bathtub, a walk-in shower, and a vanity with a mirror.

A compact kitchen with white cabinets, a microwave, a coffee maker, and a sink.

Lighthouse Inn & Suites

Hannibal

"Wonderful place to stay!"

Apartment

A spacious foyer with a grand staircase, a piano, and a large rug.

A spacious living room with a beige sofa, a dining area with a table and chairs, large windows, and a chandelier.

A spacious dining area with a round glass table, black metal chairs, and a wooden staircase leading to an upper level.

A backyard with a stone fire pit, two Adirondack chairs, and a hammock.

White House at Grand Central

Grand Center

"Staff was great and accommodating to my needs."

Cottage

A modern kitchen with stainless steel appliances, wooden cabinets, and a built-in dishwasher.

A bedroom with a bed, a ceiling fan, a window with blinds, a nightstand, and a potted plant.

A modern kitchen with dark wooden cabinets, a white countertop, a stainless steel refrigerator, and a built-in microwave. There is a dining table with two chairs and a potted plant on it.

A house with a front porch, a door, and a small garden area.

Walk to Tower Grove Park: St Louis Getaway

Tower Grove South

"great place and nice location"

Apartment

A spacious room with a wooden dining table, chairs, a chandelier, and a bed with white bedding.

A spacious living area with a blue sofa, wooden flooring, and a chandelier.

A red deck with wicker furniture and a blue umbrella, overlooking a residential area with houses and a dome-shaped building.

A modern living room with a blue sofa, a coffee table, and a ceiling fan.

Spacious 3-Bedroom with King Bed

Central West End

"Clean room nice area "

Holiday Home

A modern living room with a white sofa, a brown leather chair, a wooden staircase, and a flat-screen TV mounted on the wall.

A modern kitchen with green cabinets, stainless steel appliances, and a wooden dining table with chairs.

A bedroom with a large bed, a bench, a door, and a ceiling light.

A modern living room with a white sofa, a brown leather armchair, a small coffee table, and a chandelier.

Wine Country Getaway | JZ Vacation Rentals

Washington

"Great communication, had a couple of leaks and shower flooded but the maintenance came right away to fix it. Overall clean, AC/Heat unit in each room, big kitchen, wonderful sitting area and decor."

Cottage

A modern living room with a grey sofa, a dining table with chairs, a small side table, and a floor lamp.

A kitchen with white cabinets, a granite countertop, a stainless steel refrigerator, a microwave, a toaster, and a coffee maker.

A forest clearing with several discarded tires and a rope swing.

A modern kitchen with white cabinets, a black refrigerator, and a dining area with a blue table runner.

Peaceful Missouri Cabin Rental on 55 Acres!

Canton

"This is a great place to stay if you want to get away from the city. Rural enough to be quiet, but within easy driving distance to a city. Also perfect if you just want to stay on the property and really get away from city life, just bring your groceries. "

Cottage

A covered porch with metal siding, a white door, and two folding chairs.

A bedroom with a bed, a desk with a chair, a dresser, a ceiling fan, and a window with blinds.

A modern kitchen with white cabinets, a granite countertop, a built-in stove, a microwave, and a stainless steel refrigerator.

A living room with a beige sofa, a coffee table, a TV mounted on the wall, and a chair.

Updated Missouri Cabin Rental on Large Farm

Canton

"The cabin rental was a great stay. Had some connection problems with the t.v. couldn't get past the check out date. The wifi was easy to hook up. The cabin was clean and smelled fresh. Did have some problems with ants on the countertop. Great place to stay, enjoyed our visit."

Apartment

A wooden dock extending into a calm lake surrounded by lush greenery.

A swimming pool with lounge chairs and a house in the background.

A white two-story house with a wooden deck and a staircase leading to the front door.

A dining area with a wooden table, chairs, and a fruit basket.

Charming Berger Apt on 42-acre Farm w/ Pool Access

Berger

Apartment

A living room with a sofa, armchair, and coffee table. There is a ceiling fan, a TV mounted on the wall, and a window with blinds.

A bedroom with a bed, a TV, a ceiling fan, and a hallway leading to another room.

A wooden deck with railings, a concrete foundation, and a view of a residential area with houses and trees.

A white door with a small mailbox and a mailbox with a bear figure on the front step.

Walk to Carondelet Park: Quiet Couple's Getaway

Carondelet

"We had a nice stay, close to things we wanted to do"

Apartment

A modern kitchen with a wooden ceiling, a dining area with stools, and a seating area with a bench.

A compact kitchen with a wooden ceiling, a small seating area, and a dining table.

A bedroom with a wooden ceiling, two windows with blinds, a bed with a striped blanket, a bedside table, and a white fan.

An outdoor patio with wooden benches and a covered seating area, surrounded by a gravel path and a fence.

The Merlot Bungalow Defiance Tiny Home on Trail

Defiance

"We enjoyed our stay very much! The place was very cute and conveniently located to explore Defiance! We will look to stay here again in the future!"

Apartment

A red building with a sign for 'Catala House' and a 'Massage House' sign.

A cozy loft-style living room with a brown leather sofa, a blue ottoman, and a patterned rug.

A bedroom with a bed, a flat-screen TV mounted on the wall, a brick pillar, and a window with curtains.

A red building with a balcony, a staircase, and outdoor seating with a blue umbrella.

New Melle Apartment Near Missouri Wine Country

Wentzville

"Apartment was wonderful! Very spacious and lots of furniture. Had a flat screen in the living room and bedroom that included Netflix and Prime. Air conditioner worked very well. Was very quiet and in a good location. Property manager was very friendly. There was even a very nice tea selection included with our stay. All amenities including, fridge, sinks, countertop burner, shower, washer, dryer, and toilet worked with no issues. All the dishes and mugs were clean. Plenty of towels to use during...

Cottage

A log cabin interior with a stone fireplace, leather furniture, and mounted animal heads on the walls.

A kitchen with wooden cabinets, a stone island, and a hanging deer head.

A kitchen with wooden cabinets, granite countertops, a stainless steel stove, and a hanging light fixture.

A log cabin with a deck, outdoor seating, and potted plants.

Spacious Ozarks Family Home - Private Pool & Grill

Bourbon

"It's perfect 100% recommended."

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Stay near popular Northeast Missouri attractions

A baseball stadium with a large crowd, a prominent arch structure, and various advertisements.

Busch Stadium

9.4/10 (4,850 reviews)

Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's acclaimed art galleries or attend a baseball game.

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A bronze elephant sculpture with a pumpkin on its back, surrounded by greenery.

St. Louis Zoo

9.2/10 (4,367 reviews)

In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.

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A cityscape with a prominent statue in the center, surrounded by various buildings and a large stadium.

Enterprise Center

8.8/10 (1,597 reviews)

Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's acclaimed art galleries or attend a baseball game.

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A cityscape with a prominent arch structure, various high-rise buildings, and a large government building.

Dome at America’s Center

8.4/10 (1,229 reviews)

Catch an event at Dome at America’s Center during your trip to St. Louis. Experience the area's great live music and fascinating museums.

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A modern building with large glass windows, surrounded by a garden with red and pink tulips and purple flowers.

Forest Park

9.2/10 (3,389 reviews)

Nature, history and cultural institutions come together in one of the United States’ largest urban parks, which buzzes with St. Louis’ dynamic community spirit.

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A historic building with a large lawn, a flagpole with flags, and a clear blue sky.

St. Louis University

8.6/10 (526 reviews)

Explore the campus of St. Louis University during your stay in St. Louis. Wander around the area's picturesque gardens or experience its fascinating museums.

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A tightrope walker balancing on a wire between buildings.

City Museum

9.0/10 (3,209 reviews)

This quirky children’s museum invites visitors to crawl through whales, climb into tree houses and whiz down three-story slides.

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America's Center Convention Complex

8.8/10 (306 reviews)

Learn about the events happening in America's Center Convention Complex during your trip to St. Louis. Experience the area's fascinating museums and acclaimed art galleries.

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Learn more about Northeast Missouri

Great live music, sports teams and popular sights from St. Louis Zoo to St. Louis Union Station—explore Northeast Missouri, a family-friendly destination also known for its theatres.

See all hotels in Northeast Missouri

A historic log cabin with a flagpole, hay bales, and autumn pumpkins.

Top Northeast Missouri Hotel Reviews

Hollywood Casino & Hotel St. Louis

10/10 Excellent

"The Hollywood Hotel and Casino is a great place to stay !"

Clayton Plaza Hotel & Extended Stay

8/10 Good

"I’d stay again"

Marriott St. Louis Grand

10/10 Excellent

"Staff was friendly and helped extremely well. My stay was made great and the convention was great"

Home2 Suites by Hilton St. Louis Downtown

10/10 Excellent

"Clean, comfortable great staff. We did have an issue with someone having used the bathroom in our room prior to our check in and staff insisted on moving us to a different room."

Forest Park Hotel by MDR

8/10 Good

"Free parking, clean big room, with microwave and fridge and affordable."

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

10/10 Excellent

"Staff were friendly and helpful. Room and common areas were clean. We like that our dog was able to stay with us for no extra charge. The only negative thing I'd mention is that the TV in our room kept going in and out. The picture and audio were glitching. Not the end of the world though. We both noted that the mattress and pillows were quite comfortable. I'm definitely going to be staying here while visiting again."

Pear Tree Inn St. Louis Near Union Station

10/10 Excellent

"It was a good location and very good experience"

More cheap stays in Northeast Missouri

Motel 6 Hazelwood, MO

5781 Campus Ct Hazelwood MO

฿1,945

฿2,377 total

31 Aug - 1 Sept

includes taxes & fees

8.4/10 Very good! (2,172 reviews)

Days Inn and Suites by Wyndham St. Louis/Westport Plaza

1970 Craig Rd Maryland Heights MO

฿2,223

฿2,578 total

1 Sept - 2 Sept

includes taxes & fees

Best Western St. Louis Inn

6224 Heimos Industrial Park Dr St. Louis MO

฿2,329

฿2,678 total

17 Sept - 18 Sept

includes taxes & fees

Pear Tree Inn St. Louis Arnold

1201 Drury Ln Arnold MO

฿2,942

฿3,400 total

30 Aug - 31 Aug

includes taxes & fees

9.4/10 Exceptional! (1,015 reviews)

Pear Tree Inn St. Louis Airport

10810 Pear Tree Ln St. Ann MO

฿2,942

฿3,463 total

31 Aug - 1 Sept

includes taxes & fees

Tru By Hilton St. Louis Downtown

1221 Locus Street St. Louis MO

฿3,190

฿3,730 total

7 Sept - 8 Sept

includes taxes & fees

7.8/10 Good! (944 reviews)

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Book Hotels in Northeast Missouri on Expedia.com

Find hotels in Northeast Missouri, MO from ฿2,350

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Northeast Missouri

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Northeast Missouri hotels

1. Depot Inn and Suites

2. Oak Hill Inn & Suites

3. Quality Inn & Suites Hannibal West

4. Holiday Inn Express & Suites St Peters by IHG

5. Pear Tree Inn St. Louis Airport

6. Best Western On The River

7. Sleep Inn & Suites Hannibal West

8. Pinemark Inn & Suites

9. Wingate by Wyndham St. Louis Airport

10. Best Western Plus Washington Hotel

11. Drury Inn & Suites St. Louis Airport

12. Hyatt Select St. Louis Airport

13. Quality Inn Foristell

14. Holiday Inn Express & Suites Wentzville St Louis West by IHG

15. Comfort Inn Sullivan

16. Hyatt Place St. Louis/Chesterfield

17. Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

18. Hampton Inn & Suites St. Louis at Forest Park

19. Sleep Inn & Suites O'Fallon MO - Technology Drive

20. Super 8 by Wyndham Kirksville-University Area

Holiday Rentals in Northeast Missouri

Cannon Dam Cabins

Lighthouse Inn & Suites

White House at Grand Central

Walk to Tower Grove Park: St Louis Getaway

Spacious 3-Bedroom with King Bed

Wine Country Getaway | JZ Vacation Rentals

Peaceful Missouri Cabin Rental on 55 Acres!

Updated Missouri Cabin Rental on Large Farm

Charming Berger Apt on 42-acre Farm w/ Pool Access

Walk to Carondelet Park: Quiet Couple's Getaway

The Merlot Bungalow Defiance Tiny Home on Trail

New Melle Apartment Near Missouri Wine Country

Spacious Ozarks Family Home - Private Pool & Grill

Stay near popular Northeast Missouri attractions

Busch Stadium

St. Louis Zoo

Enterprise Center

Dome at America’s Center

Forest Park

St. Louis University

City Museum

America's Center Convention Complex

Learn more about Northeast Missouri

Top Northeast Missouri Hotel Reviews

Hollywood Casino & Hotel St. Louis

Clayton Plaza Hotel & Extended Stay

Marriott St. Louis Grand

Home2 Suites by Hilton St. Louis Downtown

Forest Park Hotel by MDR

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Pear Tree Inn St. Louis Near Union Station

More cheap stays in Northeast Missouri

Motel 6 Hazelwood, MO

Days Inn and Suites by Wyndham St. Louis/Westport Plaza

Best Western St. Louis Inn

Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Airport

Tru By Hilton St. Louis Downtown

Explore a world of travel with Expedia

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