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Our top choices for North Main Street Historic District hotels

Hampton Inn Poplar Bluff
Hampton Inn Poplar Bluff4.1 km from North Main Street Historic District
9.4 out of 10, Exceptional, (832 reviews)
The price is ฿3,044
฿3,409 total
includes taxes & fees
31 May - 1 Jun

Drury Inn & Suites Poplar Bluff
Drury Inn & Suites Poplar Bluff3.5 km from North Main Street Historic District
9.2 out of 10, Wonderful, (1,008 reviews)
The price is ฿3,222
฿3,640 total
includes taxes & fees
24 May - 25 May

Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar Bluff5.3 km from North Main Street Historic District
9.4 out of 10, Exceptional, (893 reviews)
The price is ฿3,544
฿4,004 total
includes taxes & fees
9 May - 10 May

Holiday Inn Poplar Bluff by IHG
Holiday Inn Poplar Bluff by IHG4.4 km from North Main Street Historic District
8.8 out of 10, Excellent, (740 reviews)
The price is ฿2,997
฿3,385 total
includes taxes & fees
17 May - 18 May

Comfort Inn Poplar Bluff North
Comfort Inn Poplar Bluff North3.7 km from North Main Street Historic District
7.8 out of 10, Good, (411 reviews)
The price is ฿2,755
฿3,112 total
includes taxes & fees
17 May - 18 May

Motel 6 Poplar Bluff, MO
Motel 6 Poplar Bluff, MO7.3 km from North Main Street Historic District
8.0 out of 10, Very good, (1,002 reviews)
The price is ฿2,094
฿2,345 total
includes taxes & fees
9 May - 10 May

Super 8 by Wyndham Poplar Bluff Missouri
Super 8 by Wyndham Poplar Bluff Missouri4.4 km from North Main Street Historic District
6.6 out of 10, (641 reviews)
The price is ฿1,918
฿2,166 total
includes taxes & fees
14 May - 15 May

Lake Wappapello
Lake Wappapello9.3 km from North Main Street Historic District
10.0 out of 10, Exceptional, (2 reviews)
The price is ฿2,739
฿2,889 total
includes taxes & fees
9 May - 10 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Compare popular hotels close to North Main Street Historic District
Property | Property class | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included | |
|---|---|---|---|---|---|---|---|---|
![]() Hampton Inn Poplar Bluff | 9.4 Exceptional 832 reviews | View | ||||||
![]() Drury Inn & Suites Poplar Bluff | 9.2 Wonderful 1,008 reviews | View | ||||||
![]() Fairfield Inn & Suites by Marriott Poplar Bluff | 9.4 Exceptional 893 reviews | View | ||||||
![]() Holiday Inn Poplar Bluff by IHG | 8.8 Excellent 740 reviews | View | ||||||
![]() Comfort Inn Poplar Bluff North | 7.8 Good 411 reviews | View |
Top North Main Street Historic District Hotel Reviews

Hampton Inn Poplar Bluff
10/10 Excellent




































