A riverside walkway with colorful umbrellas, a stone bridge, and a red sculpture.

Search Hotels in Midtown, San Antonio

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Property class

Guest rating

Selecting then applying a filter from this group will update the results on a new page

Our top choices for Midtown hotels

1. O'Casey's Boutique Inn

O'Casey's Boutique Inn
3.0 star property
Midtown
9.0 out of 10, Wonderful, (794 reviews)
"Beautiful and cozy room. Gorgeous property that is conveniently located to Downtown, The Pearl and Trinity University. Staff was friendly and willing to go the extra-mile with assistance for your stay."
United States
Adriana
The price is ฿5,268
฿6,164 total
includes taxes & fees
5 Nov - 6 Nov
O'Casey's Boutique Inn

2. Classic 1br/1ba Charming Apt w/ Modern Upgrades

Classic 1br/1ba Charming Apt w/ Modern Upgrades
3.0 star property
Midtown
8.4 out of 10, Very good, (7 reviews)
"I believe the property could benefit from some renovation and pest control, as there were numerous bugs on the floor and counter. However, its price and proximity to downtown make it an attractive option."
United States
Hugo
The price is ฿2,488
฿4,686 total
includes taxes & fees
17 Nov - 18 Nov
Classic 1br/1ba Charming Apt w/ Modern Upgrades

3. Tx Home Group in San Antonio

Tx Home Group in San Antonio
2.0 star property
Midtown
The price is ฿5,007
฿8,555 total
includes taxes & fees
5 Nov - 6 Nov
Tx Home Group in San Antonio

4. Tx Home Group- San Antonio

Tx Home Group- San Antonio
2.0 star property
Midtown
7.8 out of 10, Good, (10 reviews)
"Great place to stay. Host really made you feel comfortable and welcomed. "
United States
Brian
The price is ฿3,676
฿6,999 total
includes taxes & fees
12 Nov - 13 Nov
Tx Home Group- San Antonio

5. Remodeled Vintage Charm 1br/1ba Apt Close to DT

Remodeled Vintage Charm 1br/1ba Apt Close to DT
3.0 star property
Midtown
6.0 out of 10, (4 reviews)
"The house itself is fine. Clean and good parking. The toilet paper fixture was broken, the soap in the bathroom is cheap. They charge $200 (insane) deposit of which they decided to take $22 because i slightly stained their crappy white towels with a smudge of makeup. They claimed that they couldnt be cleaned so they deducted that from my deposit. So, be careful staining their towels "
United States
Hilda
Remodeled Vintage Charm 1br/1ba Apt Close to DT

6. Stunning 2br/1ba Historic Pad Few Steps Downtown

Stunning 2br/1ba Historic Pad Few Steps Downtown
3.5 star property
Midtown
6.0 out of 10, (2 reviews)
"Location was close to downtown and met our needs. The house was clean and in good shape. Although, I think there were a few fire detectors missing. The dock was there and the detector was not. We didn't get to use the parking spot promised in the back due to concrete repair going on. But there was ample street parking. The fridge did not work when we arrived and the owner sent maintenance the next day to fix it. All in all, we had a great time."
United States
Carrie
The price is ฿5,128
฿8,722 total
includes taxes & fees
4 Dec - 5 Dec
Stunning 2br/1ba Historic Pad Few Steps Downtown

7. La Quinta Inn & Suites by Wyndham San Antonio Downtown

La Quinta Inn & Suites by Wyndham San Antonio Downtown
3.0 star property
Arsenal, 3.7 km from Midtown
9.0 out of 10, Wonderful, (3,679 reviews)
"Great room size and amenities."
United Kingdom
Natasha
The price is ฿2,999
฿3,598 total
includes taxes & fees
24 Nov - 25 Nov
La Quinta Inn & Suites by Wyndham San Antonio Downtown

8. Hyatt Place San Antonio - Riverwalk

Hyatt Place San Antonio - Riverwalk
3.0 star property
Downtown San Antonio, 3.8 km from Midtown
9.2 out of 10, Wonderful, (1,492 reviews)
"Great place to stay. Very quiet friendly staff and good food."
United States
Allen
The price is ฿4,349
฿5,321 total
includes taxes & fees
22 Nov - 23 Nov
Hyatt Place San Antonio - Riverwalk

9. Embassy Suites San Antonio Riverwalk-Downtown

Embassy Suites San Antonio Riverwalk-Downtown
3.5 star property
Downtown San Antonio, 3 km from Midtown
9.0 out of 10, Wonderful, (1,561 reviews)
"Great place to stay"
United States
Myriam
The price is ฿4,672
฿5,605 total
includes taxes & fees
22 Nov - 23 Nov
Embassy Suites San Antonio Riverwalk-Downtown

10. Drury Plaza Hotel San Antonio Riverwalk

Drury Plaza Hotel San Antonio Riverwalk
4.0 star property
Downtown San Antonio, 3.3 km from Midtown
9.4 out of 10, Exceptional, (5,477 reviews)
"Will definitely stay again!"
United States
Felicia
The price is ฿4,315
฿5,150 total
includes taxes & fees
8 Nov - 9 Nov
Drury Plaza Hotel San Antonio Riverwalk

11. Omni La Mansion del Rio

Omni La Mansion del Rio
4.0 star property
Downtown San Antonio, 3.1 km from Midtown
9.4 out of 10, Exceptional, (3,021 reviews)
"We enjoyed our stayed. Friendly staff and restaurant was amazing!"
United States
Raisa Janeth
The price is ฿5,368
฿6,502 total
includes taxes & fees
24 Nov - 25 Nov
Omni La Mansion del Rio

12. Hampton Inn San Antonio-Downtown (River Walk)

Hampton Inn San Antonio-Downtown (River Walk)
2.5 star property
Downtown San Antonio, 3.2 km from Midtown
8.4 out of 10, Very good, (2,059 reviews)
"Great stay"
United States
India
The price is ฿3,014
฿3,615 total
includes taxes & fees
17 Nov - 18 Nov
Hampton Inn San Antonio-Downtown (River Walk)

13. Hyatt Regency San Antonio Riverwalk

Hyatt Regency San Antonio Riverwalk
4.0 star property
Downtown San Antonio, 3.2 km from Midtown
9.2 out of 10, Wonderful, (2,334 reviews)
"excellent location..food was great"
United States
Donna M
The price is ฿5,416
฿7,560 total
includes taxes & fees
22 Nov - 23 Nov
Hyatt Regency San Antonio Riverwalk

14. Sonesta ES Suites San Antonio Downtown Alamo Plaza

Sonesta ES Suites San Antonio Downtown Alamo Plaza
3.0 star property
Downtown San Antonio, 3.1 km from Midtown
8.4 out of 10, Very good, (2,247 reviews)
"Great hotel"
United States
Reyes
The price is ฿3,253
฿3,882 total
includes taxes & fees
2 Dec - 3 Dec
Sonesta ES Suites San Antonio Downtown Alamo Plaza

15. Holiday Inn Express San Antonio-Airport by IHG

Holiday Inn Express San Antonio-Airport by IHG
2.5 star property
7.6 km from Midtown
9.4 out of 10, Exceptional, (1,004 reviews)
"The rooms were very clean and beds were so comfortable."
United States
Lori
The price is ฿3,405
฿4,064 total
includes taxes & fees
29 Nov - 30 Nov
Holiday Inn Express San Antonio-Airport by IHG

16. Hotel Valencia Riverwalk, Valencia Collection

Hotel Valencia Riverwalk, Valencia Collection
4.5 star property
Downtown San Antonio, 3 km from Midtown
9.4 out of 10, Exceptional, (3,286 reviews)
"Great place to stay"
United States
Derrick
The price is ฿3,796
฿5,494 total
includes taxes & fees
19 Nov - 20 Nov
Hotel Valencia Riverwalk, Valencia Collection

17. Element by Marriott San Antonio Riverwalk

Element by Marriott San Antonio Riverwalk
4.0 star property
3.1 km from Midtown
9.2 out of 10, Wonderful, (1,463 reviews)
"Great breakfast and comfortable room"
United States
Crystal
The price is ฿3,412
฿4,071 total
includes taxes & fees
22 Nov - 23 Nov
Element by Marriott San Antonio Riverwalk

18. Hotel Gibbs Downtown Riverwalk

Hotel Gibbs Downtown Riverwalk
2.0 star property
Downtown San Antonio, 3.1 km from Midtown
9.0 out of 10, Wonderful, (2,388 reviews)
"Perfect location, excellent breakfast and beautifully decorated"
United States
Michael
The price is ฿2,889
฿3,380 total
includes taxes & fees
15 Nov - 16 Nov
Hotel Gibbs Downtown Riverwalk

19. Drury Plaza Hotel San Antonio Airport

Drury Plaza Hotel San Antonio Airport
3.0 star property
7.5 km from Midtown
9.4 out of 10, Exceptional, (2,323 reviews)
"Great place to stay and the covered parking is convenient when traveling"
United States
Darlene
The price is ฿3,843
฿4,587 total
includes taxes & fees
8 Nov - 9 Nov
Drury Plaza Hotel San Antonio Airport

20. Hilton Palacio Del Rio

Hilton Palacio Del Rio
4.0 star property
Downtown San Antonio, 3.5 km from Midtown
9.2 out of 10, Wonderful, (1,325 reviews)
"Great location and the staff was great!"
United States
Laurie Ann
The price is ฿5,502
฿6,566 total
includes taxes & fees
15 Nov - 16 Nov
Hilton Palacio Del Rio
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels in Midtown

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A covered porch with a wooden table and chairs, surrounded by potted plants and a railing.
O'Casey's Boutique Inn
3.0 star property
9.0
Wonderful
794 reviews
View
A modern kitchen with a white stove, a ceiling fan, and a dining area with a table and chairs.
Classic 1br/1ba Charming Apt w/ Modern Upgrades
3.0 star property
8.4
Very good
7 reviews
View
A modern kitchen with stainless steel appliances, wooden cabinets, granite countertops, and pendant lighting.
Tx Home Group- San Antonio
2.0 star property
7.8
Good
10 reviews
View
A compact living space with a dining area, kitchen, and a sofa.
Remodeled Vintage Charm 1br/1ba Apt Close to DT
3.0 star property
6.0
4 reviews
View
A two-story house with a blue exterior, a yellow front door, and a white picket fence.
Stunning 2br/1ba Historic Pad Few Steps Downtown
3.5 star property
6.0
2 reviews
View

Where to stay in Midtown

Find the best Midtown areas for the activities you enjoy most.

Downtown San Antonio

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

Uptown Central

If you're spending some time in Uptown Central, Marion Koogler McNay Art Museum and Alamo Quarry Market are top sights worth seeing.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

Medical Center District

While Medical Center District isn't home to many top sights, Wonderland of the Americas Mall and Huebner Oaks are some notable places to visit nearby.

Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Crystal Ice Palace are top sights worth seeing.

Top Midtown Hotel Reviews

Frequently asked questions

What's it like in Midtown?
Midtown is a neighbourhood that travellers like for its riverfront, bars and libraries. Are you looking for Midtown travel tips? Make sure that you visit The DoSeum and San Antonio Zoo and Aquarium while you're in the neighbourhood.
Where is the best place to stay in Midtown?
Based on Expedia customer reviews, O'Casey's Boutique Inn is the highest ranked property in Midtown. This B&B offers free breakfast and free parking.
How many hotels will I be able to find in the Midtown area?
If you're searching for places to stay in San Antonio, Expedia has something to meet your needs with 232 Midtown hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in Midtown, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might be able to still cancel and be given a refund within 24 hours of booking. Add your dates and click on "Search", then you can filter by "fully refundable" to review the best deals in Midtown.
What are the top things to see and do in Midtown?
Attractions such as Paper Tiger, Stable Hall in Pearl Brewery - San Antonio and Sam's Burger Joint highlight San Antonio's cultural scene. As you're discovering the neighbourhood, The DoSeum and San Antonio Zoo and Aquarium are some other places worth a visit. Alamo and Alamodome are some popular places to visit in the area around Midtown. While you're out sightseeing in San Antonio, make sure that you visit other sights such as The Mix or McFarlin Tennis Center.

Explore a world of travel with Expedia