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Check prices for these dates

This weekend
17 Jul - 19 Jul
Next weekend
24 Jul - 26 Jul

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Our top choices for Mesopotamia hotels

Interior

To Spiti tis Sofias

To Spiti tis Sofias
Kastoria
10.0 out of 10, Exceptional, (1 review)
"Tout simplement le meilleur de notre voyage en Grèce. Simple mais tellement mieux qu'ailleurs. Accueil parfait, chambre confortable et petit déjeuner de roi. Je reviendrais à 100% si je passe dans le coin. "
France
Anonymous traveller
The price is ฿2,175
฿2,546 total
includes taxes & fees
11 Aug - 12 Aug
To Spiti tis Sofias
Terrace/patio

Chloe Hotel

Chloe Hotel
3.0 star property
Kastoria
10.0 out of 10, Exceptional, (88 reviews)
"Exceptional service, clean environment, superb breakfast and attentive staff."
United States
Tammy
The price is ฿3,536
฿4,207 total
includes taxes & fees
17 Jul - 18 Jul
Chloe Hotel
Property grounds

Calma Hotel & Spa

Calma Hotel & Spa
4.0 star property
Kastoria
9.6 out of 10, Exceptional, (37 reviews)
"Pleasant stay. Good amenities. Great staff. "
New Zealand
Robert
The price is ฿3,349
฿4,186 total
includes taxes & fees
20 Jul - 21 Jul
Calma Hotel & Spa
Property grounds

Anesis Hotel

Anesis Hotel
2.0 star property
Kastoria
9.0 out of 10, Wonderful, (9 reviews)
"Fantastic hotel in the heart of Kastoria. The owners are lovely people, very helpful and made me feel right at home. Will definitely stay there again!"
Canada
Adam
The price is ฿1,846
฿2,172 total
includes taxes & fees
11 Aug - 12 Aug
Anesis Hotel
Exterior

Le Marron

Le Marron
4.0 star property
Voio
8.0 out of 10, Very good, (1 review)
The price is ฿4,030
฿4,959 total
includes taxes & fees
16 Jul - 17 Jul
Le Marron
House | 3 bedrooms, Internet

The Sunset Haven Kastoria Modern Lake Elegance

The Sunset Haven Kastoria Modern Lake Elegance
Kastoria
The price is ฿1,667
฿6,920 total
includes taxes & fees
16 Jul - 17 Jul
The Sunset Haven Kastoria Modern Lake Elegance
Front of property – evening/night

Hotel Anastassiou

Hotel Anastassiou
2.0 star property
Kastoria
8.0 out of 10, Very good, (70 reviews)
"Nice simple stay."
United States
Jeffrey
The price is ฿1,515
฿1,797 total
includes taxes & fees
14 Aug - 15 Aug
Hotel Anastassiou
Outdoor dining

OIKOI - Luxury Suites & Maisonettes

OIKOI - Luxury Suites & Maisonettes
Kastoria
The price is ฿3,322
฿4,611 total
includes taxes & fees
9 Aug - 10 Aug
OIKOI - Luxury Suites & Maisonettes
Exterior

Guest House Ilektra

Guest House Ilektra
Voio
9.8 out of 10, Exceptional, (11 reviews)
"Friendly and courteous hosts, great food and excellent service "
United States
Pantelia
The price is ฿2,013
฿2,362 total
includes taxes & fees
1 Aug - 2 Aug
Guest House Ilektra
Indoor pool

Esperos Palace Luxury & Spa Hotel

Esperos Palace Luxury & Spa Hotel
4.0 star property
Kastoria
9.0 out of 10, Wonderful, (84 reviews)
"The hotel is beautiful, large room with balcony. Grate bathroom, comfortable, the dinner is good ,however the breakfast was amazing. "
United States
Michal
The price is ฿3,944
฿4,862 total
includes taxes & fees
16 Jul - 17 Jul
Esperos Palace Luxury & Spa Hotel
Lunch and dinner served

Guesthouse Monopati

Guesthouse Monopati
Amyntaio
10.0 out of 10, Exceptional, (3 reviews)
The price is ฿2,431
฿2,837 total
includes taxes & fees
22 Jul - 23 Jul
Guesthouse Monopati
Terrace/patio

Orologopoulos Mansion

Orologopoulos Mansion
5.0 star property
Kastoria
9.6 out of 10, Exceptional, (37 reviews)
"Wonderful stay Very well kept hotel Nice room with a warm feeling The spaces in hotel are beautiful and give you the feeling that you stay at a luxurious home Very good breakfast- I will definitely stay here again "
United Kingdom
elyahu
The price is ฿4,102
฿5,232 total
includes taxes & fees
19 Jul - 20 Jul
Orologopoulos Mansion
Egyptian cotton sheets, premium bedding, down duvets, pillow-top beds

Kyknos De Luxe Hotel

Kyknos De Luxe Hotel
Kastoria
10.0 out of 10, Exceptional, (43 reviews)
"Very nice clean, very polite staff and great breakfast!"
United States
Vasilios
The price is ฿2,963
฿3,442 total
includes taxes & fees
27 Jul - 28 Jul
Kyknos De Luxe Hotel
Apartment | Interior

Lūma Retreat

Lūma Retreat
Kastoria
The price is ฿2,455
฿2,864 total
includes taxes & fees
16 Jul - 17 Jul
Lūma Retreat
Exterior

Arhontiko Christodoulou

Arhontiko Christodoulou
2.0 star property
Prespes
The price is ฿2,416
฿2,820 total
includes taxes & fees
3 Aug - 4 Aug
Arhontiko Christodoulou
House | 2 bedrooms

Anastasia s Kastoria Cozy Modern Garden Retreat

Anastasia s Kastoria Cozy Modern Garden Retreat
Kastoria
The price is ฿1,463
฿3,471 total
includes taxes & fees
19 Jul - 20 Jul
Anastasia s Kastoria Cozy Modern Garden Retreat
Restaurant

Guesthouse Vissinokipos

Guesthouse Vissinokipos
Kastoria
9.4 out of 10, Exceptional, (10 reviews)
"Wonderfull view and very friendly people.the place is avery dpecial artistic decorated.wonderfull weather.nice varieties for breakfast.price was ver good.i recommend it!"
United States
Carmen
The price is ฿2,425
฿2,830 total
includes taxes & fees
19 Jul - 20 Jul
Guesthouse Vissinokipos
Exterior

Andromeda Boutique hotel

Andromeda Boutique hotel
4.0 star property
Kastoria
8.8 out of 10, Excellent, (3 reviews)
The price is ฿2,121
฿3,174 total
includes taxes & fees
20 Jul - 21 Jul
Andromeda Boutique hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mesopotamia Hotel Reviews

Orologopoulos Mansion

Orologopoulos Mansion

10/10 Excellent
"This is the hotel we return to time and time again, and the one we are never disappointed by. * Clean: Perfectly clean. Daily refresh of linens and tidying of room. Public spaces pristine. Black out shades were a pleasant surprise in an antique building like this one. Loved that touch! * Customer service. Top-tier service. Warm and friendly but also give space. * Breakfast. Delicious pites, pastries, yogurt. Choice of barista-quality coffees. Lovely space to eat, both inside and outside in their private garden. * Location. One block from the lake (GREAT for jogging) and across the street from the plateia (square), with its choice of chic restaurants. Quiet when you need it to be. * Parking. Right in front every day, with no issue whatsoever. Always a perfect stay. Love this hotel!"
Paula 3-night trip
Posted 1 hour ago
Orologopoulos Mansion

More cheap stays in Mesopotamia

Hotel Anastassiou

Hotel Anastassiou

1st km Highway Kastoria-Athens Kastoria Western Macedonia
The price is ฿1,515 per night from 14 Aug to 15 Aug
฿1,515
฿1,797 total
14 Aug - 15 Aug
includes taxes & fees

Frequently asked questions

Where is the best place for a stay in Mesopotamia?
To Spiti tis Sofias is one of the top choices for your stay based on our traveller data. This guest house offers free parking and free WiFi. Two other choices for your stay in the area are Limneon Resort & Spa and Esperos Palace Luxury & Spa Hotel. See all available top hotels, or vacation rentals in Mesopotamia.
What are some of the best holiday rentals that Mesopotamia has to offer?
Anastasia s Kastoria Cozy Modern Garden Retreat: This holiday home rental outside of Mesopotamia offers a garden, a BBQ and free WiFi to help you feel perfectly comfortable in your new surroundings. This holiday rental also comes with free parking to give you added peace of mind. See all vacation rentals in Mesopotamia.
If I need to cancel my hotel reservation in Mesopotamia, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If your reservation is non-refundable, you might be able to cancel it and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Mesopotamia.
What is staying in Mesopotamia like?
Travellers to Mesopotamia will find plenty to explore and enjoy. There are 49 hotels and other accommodation options in the surrounding area. Find out more about Mesopotamia.
What are the top places to visit in Mesopotamia?
Places to visit in the wider area include Neolithic Lakeside Settlement, Kastoria Lake and Taxiarhia of the Metropolis. You'll also find Dragon's Lair and Kastoria Aquarium in the area. Take a look at what more there is to see and do in Expedia's Mesopotamia guide.
What's the seasonal weather like in Mesopotamia?
The hottest months are usually August and July, with an average temperature of 20°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for Mesopotamia is 707 mm.