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Search Hotels in Main Street Fort Pierce, Fort Pierce

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Check prices for these dates

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19 Dec - 20 Dec
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20 Dec - 21 Dec
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19 Dec - 21 Dec
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26 Dec - 28 Dec

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Our top choices for Main Street Fort Pierce hotels

Bar (on property)
The Lucie

The Lucie

The Lucie
3.0 star property
23.6 km from Main Street Fort Pierce
9.0 out of 10, Wonderful, (1005)
"Great stay, excellent staff. "
United States
Steve
The price is ฿4,665
฿6,457 total
includes taxes & fees
21 Dec - 22 Dec
The Lucie
Exterior
Hampton Inn & Suites Stuart-North

Hampton Inn & Suites Stuart-North

Hampton Inn & Suites Stuart-North
2.5 star property
26.1 km from Main Street Fort Pierce
8.8 out of 10, Excellent, (1002)
"The best possible stay in every way."
United States
Erinn
The price is ฿3,583
฿4,013 total
includes taxes & fees
22 Dec - 23 Dec
Hampton Inn & Suites Stuart-North
3 outdoor pools, open 7:00 AM to 10:00 PM, pool umbrellas, pool loungers
Marriott Hutchinson Island Beach Resort, Golf & Marina

Marriott Hutchinson Island Beach Resort, Golf & Marina

Marriott Hutchinson Island Beach Resort, Golf & Marina
4.0 star property
29.8 km from Main Street Fort Pierce
8.2 out of 10, Very good, (394)
"The room was awesome and the location was great. "
United States
Robin
The price is ฿5,344
฿7,393 total
includes taxes & fees
22 Dec - 23 Dec
Marriott Hutchinson Island Beach Resort, Golf & Marina
Desk, free WiFi, bed sheets
Home2 Suites by Hilton Stuart

Home2 Suites by Hilton Stuart

Home2 Suites by Hilton Stuart
3.0 star property
25.6 km from Main Street Fort Pierce
9.4 out of 10, Exceptional, (604)
"Love staying here. The staff are wonderful, the rooms are clean and the breakfast is decent with lots of options. "
United States
Heather
The price is ฿3,426
฿3,837 total
includes taxes & fees
21 Dec - 22 Dec
Home2 Suites by Hilton Stuart
On the beach, sun-loungers, beach umbrellas, beach towels
Hutchinson Shores Resort & Spa

Hutchinson Shores Resort & Spa

Hutchinson Shores Resort & Spa
4.0 star property
25.2 km from Main Street Fort Pierce
9.4 out of 10, Exceptional, (1000)
"Room was clean and comfortable, staff was very kind and helpful, I will definitely visit again "
United States
Andrekiss
The price is ฿6,238
฿8,395 total
includes taxes & fees
21 Dec - 22 Dec
Hutchinson Shores Resort & Spa
Outdoor spa tub
Hutchinson Island Hotel

Hutchinson Island Hotel

Hutchinson Island Hotel
2.5 star property
3.1 km from Main Street Fort Pierce
8.4 out of 10, Very good, (1352)
"The breakfast and view is the best!"
United States
Marisa
Hutchinson Island Hotel
Sun deck
Prestige Hotel Vero Beach

Prestige Hotel Vero Beach

Prestige Hotel Vero Beach
2.0 star property
20.5 km from Main Street Fort Pierce
8.4 out of 10, Very good, (1000)
"Great place"
United States
Rosa
The price is ฿4,055
฿4,542 total
includes taxes & fees
11 Jan - 12 Jan 2026
Prestige Hotel Vero Beach
Outdoor pool, pool umbrellas, pool loungers
Costa d'Este Beach Resort and Spa

Costa d'Este Beach Resort and Spa

Costa d'Este Beach Resort and Spa
4.0 star property
23 km from Main Street Fort Pierce
9.2 out of 10, Wonderful, (1001)
"Great vibe and location"
United States
Stephanie
The price is ฿7,016
฿9,337 total
includes taxes & fees
22 Dec - 23 Dec
Costa d'Este Beach Resort and Spa
Outdoor pool, pool loungers
Best Western Downtown Stuart

Best Western Downtown Stuart

Best Western Downtown Stuart
3.0 star property
29.8 km from Main Street Fort Pierce
8.6 out of 10, Excellent, (1001)
"Nice hotel for the money"
United States
Rosemary
The price is ฿3,442
฿3,854 total
includes taxes & fees
21 Dec - 22 Dec
Best Western Downtown Stuart
Breakfast, lunch, dinner served; American cuisine, beach views
Ocean Breeze Inn Vero Beach

Ocean Breeze Inn Vero Beach

Ocean Breeze Inn Vero Beach
3.5 star property
23.2 km from Main Street Fort Pierce
8.6 out of 10, Excellent, (1092)
"Love love this place! Most definitely will be back! "
United States
Silvia
The price is ฿4,275
฿4,788 total
includes taxes & fees
23 Dec - 24 Dec
Ocean Breeze Inn Vero Beach
Reception
Tru by Hilton Port St. Lucie Tradition

Tru by Hilton Port St. Lucie Tradition

Tru by Hilton Port St. Lucie Tradition
2.5 star property
23.6 km from Main Street Fort Pierce
9.2 out of 10, Wonderful, (754)
"Our stay was wonderful and your staff was very professional and friendly. I would definitely stay again also recommend your hotel to others."
United States
Anita
The price is ฿2,971
฿3,328 total
includes taxes & fees
4 Jan - 5 Jan 2026
Tru by Hilton Port St. Lucie Tradition
Property amenity
Fairfield Inn & Suites by Marriott Fort Pierce

Fairfield Inn & Suites by Marriott Fort Pierce

Fairfield Inn & Suites by Marriott Fort Pierce
2.5 star property
7.7 km from Main Street Fort Pierce
8.6 out of 10, Excellent, (1000)
"Very nice staff at check in. Very clean and nice room and bathroom. "
United States
She Anneli
The price is ฿2,912
฿3,262 total
includes taxes & fees
28 Dec - 29 Dec
Fairfield Inn & Suites by Marriott Fort Pierce
Beach nearby, beach towels
Seaspray Surf Lodge

Seaspray Surf Lodge

Seaspray Surf Lodge
2.5 star property
20.8 km from Main Street Fort Pierce
9.0 out of 10, Wonderful, (657)
"Staff was extremely courteous & friendly."
United States
Maria
Seaspray Surf Lodge
Luxury Apartment, 2 Bedrooms, 2 Bathrooms | Private kitchen | Microwave, oven, stovetop, coffee/tea maker
Sea Turtle Inn

Sea Turtle Inn

Sea Turtle Inn
2.5 star property
23.1 km from Main Street Fort Pierce
8.2 out of 10, Very good, (439)
"Very cute place. And location was great for the bonfire event."
United States
Ellen
The price is ฿4,998
฿5,598 total
includes taxes & fees
22 Dec - 23 Dec
Sea Turtle Inn
Exterior
Hampton Inn & Suites Vero Beach Downtown

Hampton Inn & Suites Vero Beach Downtown

Hampton Inn & Suites Vero Beach Downtown
2.5 star property
22.1 km from Main Street Fort Pierce
9.2 out of 10, Wonderful, (985)
"Everything was great, the staff, the property, the amenities"
United States
Julie Ann
The price is ฿4,698
฿5,262 total
includes taxes & fees
22 Dec - 23 Dec
Hampton Inn & Suites Vero Beach Downtown
King Room Sunset View Balcony | View from room
The Royal Inn Beach Hotel Hutchinson Island

The Royal Inn Beach Hotel Hutchinson Island

The Royal Inn Beach Hotel Hutchinson Island
2.5 star property
3.8 km from Main Street Fort Pierce
7.0 out of 10, Good, (1000)
"Great location and staff was great too!"
United States
Andrew
The price is ฿3,772
฿4,729 total
includes taxes & fees
26 Dec - 27 Dec
The Royal Inn Beach Hotel Hutchinson Island
Exterior
At Home Inn

At Home Inn

At Home Inn
2.5 star property
8.2 km from Main Street Fort Pierce
8.0 out of 10, Very good, (1003)
"Staff was very friendly and informative."
United States
Mary
The price is ฿1,897
฿2,124 total
includes taxes & fees
21 Dec - 22 Dec
At Home Inn
Exterior
Kimpton Vero Beach Hotel & Spa by IHG

Kimpton Vero Beach Hotel & Spa by IHG

Kimpton Vero Beach Hotel & Spa by IHG
4.0 star property
23.4 km from Main Street Fort Pierce
9.4 out of 10, Exceptional, (1001)
"Staff, room, amenities. All excellent!"
United States
Barbara
The price is ฿6,991
฿9,478 total
includes taxes & fees
5 Jan - 6 Jan 2026
Kimpton Vero Beach Hotel & Spa by IHG
On the beach
Oceanfront Inn II

Oceanfront Inn II

Oceanfront Inn II
2.0 star property
4 km from Main Street Fort Pierce
8.4 out of 10, Very good, (58)
"It was a nice hotel at a very nice location"
United States
Romey
The price is ฿3,114
฿5,564 total
includes taxes & fees
23 Dec - 24 Dec
Oceanfront Inn II
Courtyard
Star Suites: An Extended Stay Hotel

Star Suites: An Extended Stay Hotel

Star Suites: An Extended Stay Hotel
2.5 star property
24.3 km from Main Street Fort Pierce
9.6 out of 10, Exceptional, (577)
"Was perfect for our trip, will stay again! "
United States
Christopher
The price is ฿3,367
฿3,771 total
includes taxes & fees
21 Dec - 22 Dec
Star Suites: An Extended Stay Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Where to stay in Main Street Fort Pierce

Find the best Main Street Fort Pierce areas for the activities you enjoy most.

Lakewood Park

When in Lakewood Park, you can plan a visit to Lakewood Park Regional Park / Pool and Indrio Road Park / Schoolhouse, some noteworthy sights in the nearby area.

Spanish Lakes Country Club Village

While Spanish Lakes Country Club Village isn't home to many top sights, Lakewood Park Regional Park / Pool and McKee Botanical Garden are some notable places to visit nearby.

Spanish Lakes Fairways

While there might not be top attractions in Spanish Lakes Fairways, you can explore the larger area and discover places like Lakewood Park Regional Park / Pool and Indrio Road Park / Schoolhouse.

Meadowood

While Meadowood isn't home to many top sights, Endless Summer Vineyard & Winery and Indrio Road Park / Schoolhouse are some notable places to visit nearby.

Panther Woods

While Panther Woods may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Endless Summer Vineyard & Winery and Indrio Road Park / Schoolhouse.

Top Main Street Fort Pierce Hotel Reviews

Frequently asked questions

What is Main Street Fort Pierce like?
Main Street Fort Pierce is a neighbourhood that travellers like for its waterfront, art and shopping. Make sure that you visit Downtown Fort Pierce and Sunrise Theater as part of your Main Street Fort Pierce travel plans.
How many hotels will I find in Main Street Fort Pierce?
Book one of Expedia's 5 hotels and other accommodation options in Main Street Fort Pierce and start exploring everything Fort Pierce has to offer.
If I need to cancel my hotel reservation in Main Street Fort Pierce, will I receive a refund?
Yes! Most room reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of booking. Add dates, click "Search", then use the "fully refundable" filter to get the best options available in Main Street Fort Pierce.
What is there to do in this Fort Pierce neighbourhood?
For cultural attractions in Main Street Fort Pierce, head to Sunrise Theater, Art Mundo and Official Highwaymen Art Gallery. Downtown Fort Pierce and Fort Pierce City Marina are also a couple of places to visit in the neighbourhood. A few places to visit in the area around Main Street Fort Pierce include Fort Pierce Farmer's Market, Manatee Education and Observation Center and House of Seven Gables. A.E. Backus Museum and Marina at Fort Pierce are also worth a visit when you're out sightseeing in Fort Pierce.