Search Hotels in Main Street Fort Pierce, Fort Pierce

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Main Street Fort Pierce hotels

Road Runner Travel Resort - Caravan Park

Road Runner Travel Resort - Caravan Park
2.5 star property
7 km from Main Street Fort Pierce
9.4 out of 10, Exceptional, (98 reviews)
"Kitchen had a couple sets of dinnerware and pretty clean. Unfortunately, the pool was closed at the time of my visit."
United States
Blaise
The price is ฿5,670
฿6,350 total
includes taxes & fees
4 Apr - 5 Apr
Road Runner Travel Resort - Caravan Park

Coastal Haven Retreat

Coastal Haven Retreat
3.0 star property
26.3 km from Main Street Fort Pierce
The price is ฿7,270
฿22,392 total
includes taxes & fees
28 Mar - 29 Mar
Coastal Haven Retreat

Beach Villas

Beach Villas
3.0 star property
30.3 km from Main Street Fort Pierce
The price is ฿11,080
฿13,806 total
includes taxes & fees
8 Apr - 9 Apr
Beach Villas

Hutchinson Shores Resort & Spa

Hutchinson Shores Resort & Spa
4.0 star property
25.2 km from Main Street Fort Pierce
9.4 out of 10, Exceptional, (1,001 reviews)
"Beautiful and clean place"
United States
Allyson
The price is ฿8,391
฿10,802 total
includes taxes & fees
6 Apr - 7 Apr
Hutchinson Shores Resort & Spa

Mins to Beaches & HCA Hospital: Fort Pierce Home

Mins to Beaches & HCA Hospital: Fort Pierce Home
3.0 star property
Lakewood Park, 10.9 km from Main Street Fort Pierce
The price is ฿4,586
฿12,739 total
includes taxes & fees
28 Mar - 29 Mar
Mins to Beaches & HCA Hospital: Fort Pierce Home

voco Sandpiper All-Inclusive Resort by IHG

voco Sandpiper All-Inclusive Resort by IHG
3.5 star property
22.6 km from Main Street Fort Pierce
8.4 out of 10, Very good, (39 reviews)
"Beautiful location. Great amenities - we truly enjoyed our stay and will go back. "
United States
Catharine
The price is ฿10,050
฿12,530 total
includes taxes & fees
14 Apr - 15 Apr
voco Sandpiper All-Inclusive Resort by IHG

The Driftwood Resort

The Driftwood Resort
3.0 star property
22.9 km from Main Street Fort Pierce
9.0 out of 10, Wonderful, (198 reviews)
"Room, staff, on site restaurant, view. All excellent "
United States
Maria
The price is ฿7,480
฿8,541 total
includes taxes & fees
15 Apr - 16 Apr
The Driftwood Resort

The Caribbean Court Boutique Hotel

The Caribbean Court Boutique Hotel
3.0 star property
20.6 km from Main Street Fort Pierce
9.2 out of 10, Wonderful, (886 reviews)
"Very clean room, excellent cleaning staff. Quiet location, across the street from the path to the beach, beautiful beach and chairs/umbrellas/wheelie available at Inn, heated, clean pool a bonus, they accept dogs, and Amy is very friendly and helpful. Only a couple of miles from the center of Vero. A great little secret find!"
United States
Lynda
The price is ฿6,900
฿7,728 total
includes taxes & fees
31 Mar - 1 Apr
The Caribbean Court Boutique Hotel

The Islander Inn

The Islander Inn
2.0 star property
22.9 km from Main Street Fort Pierce
9.6 out of 10, Exceptional, (78 reviews)
"Pool was great! Staff was very friendly and would definitely recommend! Also was close to many nice restaurants and a general store!"
United States
Richard
The price is ฿7,783
฿8,717 total
includes taxes & fees
26 Mar - 27 Mar
The Islander Inn

Prestige Hotel Vero Beach

Prestige Hotel Vero Beach
2.0 star property
20.5 km from Main Street Fort Pierce
8.4 out of 10, Very good, (1,006 reviews)
"Beautiful peaceful beach"
United States
Lisa
The price is ฿4,503
฿5,044 total
includes taxes & fees
13 Apr - 14 Apr
Prestige Hotel Vero Beach

Seaspray Surf Lodge

Seaspray Surf Lodge
2.5 star property
20.8 km from Main Street Fort Pierce
9.0 out of 10, Wonderful, (679 reviews)
"Wonderful staff, clean room, close to the beach."
United States
Penelope
Seaspray Surf Lodge

Hampton Inn & Suites Stuart-North

Hampton Inn & Suites Stuart-North
2.5 star property
26 km from Main Street Fort Pierce
8.8 out of 10, Excellent, (1,000 reviews)
"Great service and breakfast. "
United States
Clara
The price is ฿4,225
฿4,711 total
includes taxes & fees
2 Apr - 3 Apr
Hampton Inn & Suites Stuart-North

Ocean Breeze Inn Vero Beach

Ocean Breeze Inn Vero Beach
3.5 star property
23.2 km from Main Street Fort Pierce
8.6 out of 10, Excellent, (1,153 reviews)
"Very nice place to be stranded during the snow storm up in New England. Really enjoyed my stay would go back. "
United States
elizabeth j power
The price is ฿4,976
฿5,573 total
includes taxes & fees
20 Apr - 21 Apr
Ocean Breeze Inn Vero Beach

Old Colorado Inn

Old Colorado Inn
3.5 star property
28.5 km from Main Street Fort Pierce
9.8 out of 10, Exceptional, (711 reviews)
"Great place in downtown Stuart. I would highly recommend it as a nice clean spot to stay. Very responsive and directly downtown. Excellent place. "
United States
Kevin
The price is ฿12,302
฿13,716 total
includes taxes & fees
4 Apr - 5 Apr
Old Colorado Inn

Star Suites: An Extended Stay Hotel

Star Suites: An Extended Stay Hotel
2.5 star property
24.2 km from Main Street Fort Pierce
9.6 out of 10, Exceptional, (622 reviews)
"Best experience ive had in a hotel. The room and price were amazing "
United States
David
The price is ฿3,776
฿4,229 total
includes taxes & fees
5 Apr - 6 Apr
Star Suites: An Extended Stay Hotel

Best Western Port St. Lucie

Best Western Port St. Lucie
2.5 star property
14 km from Main Street Fort Pierce
8.6 out of 10, Excellent, (1,000 reviews)
"Staff was very nice, friendly and accommodating from check-in to check-out. Rooms, breakfast area, lobby and grounds were very clean. Convenient to many places in the area. "
United States
Ingrid
The price is ฿3,512
฿3,934 total
includes taxes & fees
8 Apr - 9 Apr
Best Western Port St. Lucie

Sea Turtle Inn

Sea Turtle Inn
2.5 star property
23.1 km from Main Street Fort Pierce
8.2 out of 10, Very good, (459 reviews)
"Staff was nice in the rooms were very clean.Everything was great"
United States
kevin
The price is ฿5,411
฿6,060 total
includes taxes & fees
2 Apr - 3 Apr
Sea Turtle Inn

Vistana Beach Club

Vistana Beach Club
3.5 star property
23.1 km from Main Street Fort Pierce
9.2 out of 10, Wonderful, (127 reviews)
"Our room was fantastic and the front desk staff was always so helpful!"
United States
Adam Tyler Vande
The price is ฿9,854
฿11,037 total
includes taxes & fees
20 Apr - 21 Apr
Vistana Beach Club

Econo Lodge Vero Beach - Downtown

Econo Lodge Vero Beach - Downtown
2.5 star property
20.1 km from Main Street Fort Pierce
6.6 out of 10, (333 reviews)
"This place was totally filthy."
United States
Ida
The price is ฿3,317
฿3,715 total
includes taxes & fees
24 Apr - 25 Apr
Econo Lodge Vero Beach - Downtown

Home2 Suites by Hilton Stuart

Home2 Suites by Hilton Stuart
3.0 star property
25.6 km from Main Street Fort Pierce
9.4 out of 10, Exceptional, (635 reviews)
"All the staff was pleasant. Breakfast was great. Would stay again"
United States
David
The price is ฿3,878
฿4,325 total
includes taxes & fees
2 Apr - 3 Apr
Home2 Suites by Hilton Stuart
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Main Street Fort Pierce

Find the best Main Street Fort Pierce areas for the activities you enjoy most.

Lakewood Park

When in Lakewood Park, you can plan a visit to Lakewood Park Regional Park / Pool and McKee Botanical Garden, some noteworthy sights in the nearby area.

Spanish Lakes Country Club Village

While Spanish Lakes Country Club Village isn't home to many top sights, Lakewood Park Regional Park / Pool and Harbor Branch Ocean Discovery Center are some notable places to visit nearby.

Spanish Lakes Fairways

While there might not be top attractions in Spanish Lakes Fairways, you can explore the larger area and discover places like Lakewood Park Regional Park / Pool and Indrio Road Park / Schoolhouse.

Meadowood

While Meadowood isn't home to many top sights, Lakewood Park Regional Park / Pool and Sheraton Plaza Recreation Area are some notable places to visit nearby.

Panther Woods

While Panther Woods may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Lakewood Park Regional Park / Pool and Sheraton Plaza Recreation Area.

Top Main Street Fort Pierce Hotel Reviews

Frequently asked questions

What is Main Street Fort Pierce like?
Main Street Fort Pierce is a neighbourhood that travellers like for its waterfront, art and shopping. Make sure that you visit Downtown Fort Pierce and Sunrise Theater as part of your Main Street Fort Pierce travel plans.
How many hotels will I find in Main Street Fort Pierce?
Book one of Expedia's 7 hotels and other accommodation options in Main Street Fort Pierce and start exploring everything Fort Pierce has to offer.
If I need to cancel my hotel reservation in Main Street Fort Pierce, will I receive a refund?
Yes! Most room reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within 24 hours of booking. Add dates, click "Search", then use the "fully refundable" filter to get the best options available in Main Street Fort Pierce.
What is there to do in this Fort Pierce neighbourhood?
Sights like Sunrise Theater and Official Highwaymen Art Gallery can be part of your cultural tour of Main Street Fort Pierce. Downtown Fort Pierce and Fort Pierce City Marina are also a couple of places to visit in the neighbourhood. A few places to visit in the area around Main Street Fort Pierce include Fort Pierce Farmer's Market, Manatee Education and Observation Center and House of Seven Gables. A.E. Backus Museum and Marina at Fort Pierce are also worth a visit when you're out sightseeing in Fort Pierce.