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21 Dec - 22 Dec
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22 Dec - 23 Dec
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26 Dec - 28 Dec
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Our top choices for Main Street Cultural District hotels

Free daily full breakfast
Iowa House

Iowa House

Iowa House
3.0 star property
3.1 km from Main Street Cultural District
9.6 out of 10, Exceptional, (818)
"Nice and clean room, very friendly staffs, and great breakfast!"
United States
Xiaoyu
Iowa House
Exterior
SpringHill Suites by Marriott Ames

SpringHill Suites by Marriott Ames

SpringHill Suites by Marriott Ames
2.5 star property
2.9 km from Main Street Cultural District
9.4 out of 10, Exceptional, (539)
"Room was clean! Staff was great!"
United States
Donna
The price is ฿2,921
฿3,271 total
includes taxes & fees
23 Dec - 24 Dec
SpringHill Suites by Marriott Ames
Reception
Hampton Inn & Suites Ames

Hampton Inn & Suites Ames

Hampton Inn & Suites Ames
2.5 star property
3.2 km from Main Street Cultural District
9.4 out of 10, Exceptional, (559)
"Very nice clean hotel. "
United States
Shawn
The price is ฿2,575
฿2,885 total
includes taxes & fees
27 Dec - 28 Dec
Hampton Inn & Suites Ames
Exterior
Courtyard by Marriott Ames

Courtyard by Marriott Ames

Courtyard by Marriott Ames
3.0 star property
2.1 km from Main Street Cultural District
9.2 out of 10, Wonderful, (282)
"The room was clean. The staff was attentive and polite. "
United States
Kimberly
The price is ฿2,858
฿3,201 total
includes taxes & fees
11 Jan - 12 Jan 2026
Courtyard by Marriott Ames
BBQ/picnic Area
TownePlace Suites by Marriott Ames

TownePlace Suites by Marriott Ames

TownePlace Suites by Marriott Ames
3.0 star property
2.9 km from Main Street Cultural District
9.2 out of 10, Wonderful, (268)
"Wonderful place to stay "
United States
Lisa
The price is ฿3,444
฿3,857 total
includes taxes & fees
26 Dec - 27 Dec
TownePlace Suites by Marriott Ames
Lobby
Comfort Inn and Suites Ames near ISU Campus

Comfort Inn and Suites Ames near ISU Campus

Comfort Inn and Suites Ames near ISU Campus
2.5 star property
1.8 km from Main Street Cultural District
9.0 out of 10, Wonderful, (989)
"Very clean and close to where we wanted to visit. "
United States
Nancy
The price is ฿2,643
฿2,960 total
includes taxes & fees
11 Jan - 12 Jan 2026
Comfort Inn and Suites Ames near ISU Campus
Property amenity
Staybridge Suites Ames by IHG

Staybridge Suites Ames by IHG

Staybridge Suites Ames by IHG
3.0 star property
3 km from Main Street Cultural District
8.8 out of 10, Excellent, (89)
"Very clean rooms, friendly staff, great Breakfast🤗"
United States
Sandy
The price is ฿2,921
฿3,271 total
includes taxes & fees
28 Dec - 29 Dec
Staybridge Suites Ames by IHG
Front of property – evening/night
Holiday Inn Express & Suites Ames by IHG

Holiday Inn Express & Suites Ames by IHG

Holiday Inn Express & Suites Ames by IHG
2.5 star property
3.2 km from Main Street Cultural District
8.6 out of 10, Excellent, (411)
"Great room and friendly staff"
United States
Brandi
The price is ฿2,670
฿2,990 total
includes taxes & fees
23 Dec - 24 Dec
Holiday Inn Express & Suites Ames by IHG
Lobby sitting area
Fairfield Inn & Suites by Marriott Ames

Fairfield Inn & Suites by Marriott Ames

Fairfield Inn & Suites by Marriott Ames
2.5 star property
3.2 km from Main Street Cultural District
8.6 out of 10, Excellent, (427)
"wonderful staff and amenities ,clean, easy access to the rest of the area."
United States
Clark
The price is ฿2,638
฿2,955 total
includes taxes & fees
24 Dec - 25 Dec
Fairfield Inn & Suites by Marriott Ames
Lobby
GrandStay Hotel & Suites

GrandStay Hotel & Suites

GrandStay Hotel & Suites
2.5 star property
2 km from Main Street Cultural District
8.4 out of 10, Very good, (1001)
"Large rooms."
United States
Cara
The price is ฿2,301
฿2,577 total
includes taxes & fees
22 Dec - 23 Dec
GrandStay Hotel & Suites
Indoor pool
Quality Inn & Suites Ames Conference Center Near ISU Campus

Quality Inn & Suites Ames Conference Center Near ISU Campus

Quality Inn & Suites Ames Conference Center Near ISU Campus
2.5 star property
3.2 km from Main Street Cultural District
7.0 out of 10, Good, (461)
"Friendly staff, easy check in"
United States
Michelle
The price is ฿2,059
฿2,306 total
includes taxes & fees
28 Dec - 29 Dec
Quality Inn & Suites Ames Conference Center Near ISU Campus
Studio Suite, 1 Queen Bed, Non Smoking | Jetted bathtub
Days Inn by Wyndham Ames

Days Inn by Wyndham Ames

Days Inn by Wyndham Ames
2.0 star property
0.6 km from Main Street Cultural District
6.2 out of 10, (938)
"Clean room,friendly staff "
United States
Brad
The price is ฿2,073
฿2,322 total
includes taxes & fees
2 Jan - 3 Jan 2026
Days Inn by Wyndham Ames
Terrace/patio
Home2 Suites By Hilton Ames

Home2 Suites By Hilton Ames

Home2 Suites By Hilton Ames
3.0 star property
3.1 km from Main Street Cultural District
9.4 out of 10, Exceptional, (15)
"The rooms are always clean and the staff is always so nice and welcoming! We love staying here when we come to Ames. "
Canada
Sarah
The price is ฿2,704
฿3,029 total
includes taxes & fees
28 Dec - 29 Dec
Home2 Suites By Hilton Ames
Interior detail
Loya's Little House Bed & Breakfast

Loya's Little House Bed & Breakfast

Loya's Little House Bed & Breakfast
3.5 star property
11.2 km from Main Street Cultural District
10.0 out of 10, Exceptional, (24)
"The breakfast was outstanding. Very nice property. Comfortable beds and clean rooms. Would stay there again. "
United States
Kroczak
The price is ฿2,827
฿2,968 total
includes taxes & fees
22 Dec - 23 Dec
Loya's Little House Bed & Breakfast
Indoor pool
Gateway Hotel and Conference Center at Iowa State University

Gateway Hotel and Conference Center at Iowa State University

Gateway Hotel and Conference Center at Iowa State University
3.0 star property
3.4 km from Main Street Cultural District
9.2 out of 10, Wonderful, (1195)
"Great hotel! "
United States
Eileen
The price is ฿2,516
฿2,818 total
includes taxes & fees
22 Dec - 23 Dec
Gateway Hotel and Conference Center at Iowa State University
Lobby sitting area
Spark by Hilton Ames

Spark by Hilton Ames

Spark by Hilton Ames
3.0 star property
3.5 km from Main Street Cultural District
9.0 out of 10, Wonderful, (20)
"Very nice, big room. Staff was amazingly courteous!"
United States
Bonnie
The price is ฿2,035
฿2,279 total
includes taxes & fees
28 Dec - 29 Dec
Spark by Hilton Ames
Lobby
Best Western Plus University Park Inn & Suites

Best Western Plus University Park Inn & Suites

Best Western Plus University Park Inn & Suites
2.5 star property
3.3 km from Main Street Cultural District
8.8 out of 10, Excellent, (1001)
"Staff was very courteous and very clean room."
United States
Scott
The price is ฿2,362
฿2,645 total
includes taxes & fees
22 Dec - 23 Dec
Best Western Plus University Park Inn & Suites
Lobby
Sleep Inn & Suites Ames near ISU Campus

Sleep Inn & Suites Ames near ISU Campus

Sleep Inn & Suites Ames near ISU Campus
2.5 star property
5.7 km from Main Street Cultural District
8.8 out of 10, Excellent, (1002)
"A nice quiet stay"
United States
Scott
The price is ฿1,983
฿2,221 total
includes taxes & fees
1 Jan - 2 Jan 2026
Sleep Inn & Suites Ames near ISU Campus
Breakfast and dinner served, American cuisine
Hilton Garden Inn Ames

Hilton Garden Inn Ames

Hilton Garden Inn Ames
3.0 star property
5.6 km from Main Street Cultural District
8.6 out of 10, Excellent, (841)
"Great stay"
United States
DHANYA
The price is ฿2,636
฿2,952 total
includes taxes & fees
28 Dec - 29 Dec
Hilton Garden Inn Ames
Indoor pool
AmericInn by Wyndham Ames

AmericInn by Wyndham Ames

AmericInn by Wyndham Ames
2.5 star property
3.5 km from Main Street Cultural District
8.4 out of 10, Very good, (1001)
"Yes yes very nice day will stay there again"
United States
Doss
The price is ฿2,167
฿2,427 total
includes taxes & fees
22 Dec - 23 Dec
AmericInn by Wyndham Ames
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Main Street Cultural District Hotel Reviews

Tru By Hilton Ankeny

Tru By Hilton Ankeny

10/10 Excellent
"The staff were great "
Elizabeth 1-night trip
Posted 6 days ago
Tru By Hilton Ankeny

Hotels near other Main Street Cultural District attractions

Brunnier Art Museum

4.0/5 (2 reviews)
Be inspired by the decorative art exhibits at this university museum in central Iowa, where small-town America meets global culture.
See properties

Octagon Center for the Arts

3.6/5 (9 reviews)
You can spend an afternoon studying the exhibits at Octagon Center for the Arts during your travels in Ames. In the area, you can attend a football match or basketball game.
See properties

Frequently asked questions

What's the area like around Main Street Cultural District?
Main Street Cultural District is located in Ames. This family-friendly area is known for its array of dining options and sporting events. If you're looking for a convenient place to stay, take a look at the 26 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay near Main Street Cultural District?
Gateway Hotel and Conference Center at Iowa State University is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an indoor pool. It's located 2.1 mi (3.4 km) from Main Street Cultural District. Other good choices within 5 miles include Comfort Inn and Suites Ames near ISU Campus and Best Western Plus University Park Inn & Suites.
How many hotels will I be able to find near Main Street Cultural District?
Expedia has 26 hotels and other accommodation options within a mile from Main Street Cultural District.
If I need to cancel the hotel reservation for my stay near Main Street Cultural District, will I receive a refund?
Yes! The majority of room reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within a 24-hour period of your booking. Put your dates in and click on "Search", then you can filter by "fully refundable" to view the top deals on offer near Main Street Cultural District.
What can I see and do near Main Street Cultural District?
You'll want to browse the exhibits at Brunnier Art Museum and Farm House Museum. If you have some time to wander around the area, you might stop by Hilton Coliseum, Jack Trice Stadium or Veenker Memorial Golf Course. Furman Aquatic Center and Iowa State Center are some sights worth a visit in the area.