The Best Hotels in Main Street, Ann Arbor - 2026 Updated Prices

Q: What is Main Street like?

Main Street is a neighbourhood that travellers like for its art, university setting and entertainment choices.

Q: If I need to cancel my hotel reservation in Main Street, will I receive a refund?

Yes, most hotel bookings are fully refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then you can use the "fully refundable" filter to view top deals in Main Street.

Q: What is there to do around this Ann Arbor neighbourhood?

Ann Arbor Hands On Museum, Ann Arbor Art Center and Kempf House Museum are just a few of the places to visit in and around Main Street. When you're sightseeing in Ann Arbor, Kelsey Museum of Archaeology at the University of Michigan and Hill Auditorium are also worth a stop.

A cityscape at sunset with a mix of modern and older buildings, a clear sky, and a distant view of a flat landscape.

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Our top choices for Main Street hotels

A hotel with a prominent circular sign on top, multiple floors, and a well-lit entrance.

1. Residence Inn Ann Arbor Downtown

Downtown, < 0.1 km from Main Street

Laura

฿5,979 total

includes taxes & fees

8 Nov - 9 Nov

A bar area with a long wooden table, bar stools, a chandelier, and a chalkboard with mathematical equations.

2. Graduate by Hilton Ann Arbor

Kerrytown, 0.6 km from Main Street

Christopher

฿6,284 total

includes taxes & fees

18 Oct - 19 Oct

A modern kitchen with a marble countertop, glass display cases, and neatly arranged plates and bowls.

3. AC Hotel Ann Arbor Downtown

Downtown, 0.3 km from Main Street

Peter

฿6,845 total

includes taxes & fees

18 Oct - 19 Oct

A hotel room with a bed, two chairs, a desk with a lamp, a telephone, and a framed picture on the wall.

4. Bell Tower Hotel

Central Campus Medical, 0.8 km from Main Street

Jennifer

฿7,109 total

includes taxes & fees

1 Nov - 2 Nov

A modern lobby with a staircase, seating area, and large windows overlooking a street.

5. The Vanguard Ann Arbor, Autograph Collection

Old Fourth Ward, 1.1 km from Main Street

Kassandra

฿8,560 total

includes taxes & fees

20 Oct - 21 Oct

A spacious hotel lobby with a modern design, featuring a large seating area, a bar, and a view of the cityscape through large windows.

6. Ann Arbor City Club Apartments

Downtown, 0.2 km from Main Street

Jeanne

฿11,370 total

includes taxes & fees

3 Nov - 4 Nov

A garden with a variety of flowers and plants, a balcony with potted plants, and a green fence.

7. Ann Arbor B&B Inn

Old Fourth Ward, 0.9 km from Main Street

Adam

฿6,125 total

includes taxes & fees

10 Nov - 11 Nov

A spacious indoor pool area with a spiral staircase, lounge chairs, and a dining area with tables and chairs.

8. Weber's Hotel & Restaurant

3.6 km from Main Street

Denise

฿5,661 total

includes taxes & fees

13 Oct - 14 Oct

A modern hotel lobby with a long dining table, multiple bar stools, a TV mounted on the wall, and a patterned carpet.

9. Hampton Inn & Suites Ann Arbor West

3.3 km from Main Street

JEFFREY

฿3,632 total

includes taxes & fees

1 Nov - 2 Nov

A modern hotel with a prominent entrance, multiple floors, and a well-lit facade.

10. Homewood Suites by Hilton Ann Arbor

Bryant Pattengill East, 3.5 km from Main Street

Kiana

฿4,562 total

includes taxes & fees

26 Oct - 27 Oct

A spacious lobby with a modern design, featuring a mix of seating areas and a bar.

11. Hyatt Place Ann Arbor

Bryant Pattengill East, 4.6 km from Main Street

Stephen

฿5,024 total

includes taxes & fees

25 Oct - 26 Oct

An outdoor seating area with tables and benches, a covered section with string lights, and a clear view of the street.

12. Home2 Suites By Hilton Ann Arbor South

4.3 km from Main Street

Timothy

฿4,081 total

includes taxes & fees

1 Nov - 2 Nov

An outdoor patio area with seating and a glass-enclosed restaurant.

13. Holiday Inn Express & Suites Ann Arbor - University South by IHG

5.5 km from Main Street

Elina

฿4,466 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a bed, desk, chair, and a window with curtains.

14. TownePlace Suites by Marriott Ann Arbor

4.8 km from Main Street

Laurie

฿4,062 total

includes taxes & fees

18 Oct - 19 Oct

A multi-story hotel with a covered entrance, landscaped gardens, and a clear sky at dusk.

15. Microtel Inn & Suites by Wyndham Ann Arbor

5.5 km from Main Street

Estela

฿3,245 total

includes taxes & fees

11 Oct - 12 Oct

An indoor swimming pool with multiple lanes, surrounded by lounge chairs and a sunshade.

16. Wyndham Garden Ann Arbor

3.2 km from Main Street

Rebecka

฿2,799 total

includes taxes & fees

1 Nov - 2 Nov

A modern living room with a stone fireplace, comfortable seating, and large windows offering a view of the outdoors.

17. Courtyard By Marriott Ann Arbor

Bryant Pattengill East, 4.7 km from Main Street

Eric

฿4,729 total

includes taxes & fees

26 Oct - 27 Oct

A buffet counter with various food items and a coffee machine.

18. Fairfield Inn By Marriott Ann Arbor

Bryant Pattengill East, 4.8 km from Main Street

Jennifer

฿3,841 total

includes taxes & fees

18 Oct - 19 Oct

A compact kitchen with a dining table, a microwave, a coffee maker, and a refrigerator.

19. Sonesta Simply Suites Detroit Ann Arbor

4.3 km from Main Street

Terry

฿3,201 total

includes taxes & fees

25 Oct - 26 Oct

A Hilton Garden Inn with outdoor seating, fire pits, and string lights.

20. Hilton Garden Inn Ann Arbor

4.8 km from Main Street

James

฿3,784 total

includes taxes & fees

29 Oct - 30 Oct

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Where to stay in Main Street

Find the best Main Street areas for the activities you enjoy most.

A football stadium filled with spectators, a large scoreboard, and a football field with the word "MICHIGAN" on it.

South Central

If you're spending some time in South Central, Yost Ice Arena and Michigan Stadium are top sights worth seeing.

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A cityscape with a mix of historic and modern buildings, a prominent church, and a large parking area.

Bryant Pattengill East

If you're spending some time in Bryant Pattengill East, Cobblestone Farm and Buhr Park are top sights worth seeing.

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A theater marquee with "Taylor & Co" and "Making Sense" displayed.

Downtown

If you're spending some time in Downtown, Ann Arbor Hands On Museum and Ann Arbor Art Center are top sights worth seeing.

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A modern building with vertical wooden slats and a traditional brick tower with arched windows.

Central Campus Medical

While visiting Central Campus Medical, you might make a stop by sights like University of Michigan Museum of Natural History and Hill Auditorium.

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A river with rocks, autumn foliage, and a bridge.

Burns Park

When in Burns Park, you can plan a visit to Yost Ice Arena and University of Michigan Museum of Natural History, some noteworthy sights in the nearby area.

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Top Main Street Hotel Reviews

Ann Arbor Regent Hotel & Suites

10/10 Excellent

"Excellent room. Great location. Beautiful grounds. Good breakfast."

Hyatt Place Ann Arbor

10/10 Excellent

"Lovely studio room with pullout couch and full kitchen and desk. The room was well equipped and tastefully decorated. We spent the weekend there for U-Mich graduation and were able to host our daughter and her partner to join us for a takeout meal in our studio. Staff were available and helpful. The dining area and lobby was decorated ti celebrate graduation weekend. I would definitely recommend the hotel as well for its easy access to multiple food shops, cafes and shopping options."

Graduate by Hilton Ann Arbor

8/10 Good

"I liked the restaurant and the bed in our room was very comfy. The cafe even had a gluten free muffin for breakfast! Staff was helpful and friendly. I disliked that the bathroom needed updating. The bathroom had Barn doors and the shower was very old . Shower water was very warm, though."

Americas Best Value Inn Canton

8/10 Good

"Id stay there again cuz ive had worse Very nice room. Good breakfast. Elevator was intermittent. Staff was really good actually, except one... You could tell she really didn't want to be there. The day I had showed up they just finished up on repainting a whole bunch of outdoor stuff , looked nice, although there was over spray in many areas. the place was never swept in the three days that I was there. The same litter and trash on the ground was there the whole time I was there. No signal on the tv , although everything was plugged in."

Frequently asked questions

What is Main Street like?

Main Street is a neighbourhood that travellers like for its art, university setting and entertainment choices.

If I need to cancel my hotel reservation in Main Street, will I receive a refund?

Yes, most hotel bookings are fully refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you may still be able to cancel and receive a refund within a 24-hour period of booking. Plug in your dates, click on "Search", then you can use the "fully refundable" filter to view top deals in Main Street.

What is there to do around this Ann Arbor neighbourhood?

Ann Arbor Hands On Museum, Ann Arbor Art Center and Kempf House Museum are just a few of the places to visit in and around Main Street. When you're sightseeing in Ann Arbor, Kelsey Museum of Archaeology at the University of Michigan and Hill Auditorium are also worth a stop.

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Our top choices for Main Street hotels

1. Residence Inn Ann Arbor Downtown

2. Graduate by Hilton Ann Arbor

3. AC Hotel Ann Arbor Downtown

4. Bell Tower Hotel

5. The Vanguard Ann Arbor, Autograph Collection

6. Ann Arbor City Club Apartments

7. Ann Arbor B&B Inn

8. Weber's Hotel & Restaurant

9. Hampton Inn & Suites Ann Arbor West

10. Homewood Suites by Hilton Ann Arbor

11. Hyatt Place Ann Arbor

12. Home2 Suites By Hilton Ann Arbor South

13. Holiday Inn Express & Suites Ann Arbor - University South by IHG

14. TownePlace Suites by Marriott Ann Arbor

15. Microtel Inn & Suites by Wyndham Ann Arbor

16. Wyndham Garden Ann Arbor

17. Courtyard By Marriott Ann Arbor

18. Fairfield Inn By Marriott Ann Arbor

19. Sonesta Simply Suites Detroit Ann Arbor

20. Hilton Garden Inn Ann Arbor

Where to stay in Main Street

South Central

Bryant Pattengill East

Downtown

Central Campus Medical

Burns Park

Top Main Street Hotel Reviews

Ann Arbor Regent Hotel & Suites

Frequently asked questions

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