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Check prices for these dates

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26 Dec - 27 Dec
Tomorrow
27 Dec - 28 Dec
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26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

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Our top choices for MD Anderson Cancer Center hotels

Exterior
Hotel Saint Augustine

Hotel Saint Augustine

Hotel Saint Augustine
3.5 star property
Montrose, 3.1 km from MD Anderson Cancer Center
9.6 out of 10, Exceptional, (73)
"Great hotel in a great location. Super friendly staff and great food at the hotel restaurant. "
Canada
Antonios
The price is ฿8,362
฿9,861 total
includes taxes & fees
9 Jan - 10 Jan 2026
Hotel Saint Augustine
Terrace/patio
Hilton Garden Inn Houston Medical Center, TX

Hilton Garden Inn Houston Medical Center, TX

Hilton Garden Inn Houston Medical Center, TX
3.0 star property
Texas Medical Center, 1.2 km from MD Anderson Cancer Center
9.4 out of 10, Exceptional, (1001)
"LOVE STAYING AT THE HOTEL WHEN I TRAVEL TO HOUSTON. "
United States
Ruby
The price is ฿3,089
฿3,614 total
includes taxes & fees
2 Jan - 3 Jan 2026
Hilton Garden Inn Houston Medical Center, TX
Terrace/patio
Home2 Suites by Hilton Houston Medical Center, TX

Home2 Suites by Hilton Houston Medical Center, TX

Home2 Suites by Hilton Houston Medical Center, TX
3.0 star property
Texas Medical Center, 1.2 km from MD Anderson Cancer Center
9.4 out of 10, Exceptional, (570)
"Our stay was excellent and will be back next time!"
United States
Marta
The price is ฿4,051
฿4,740 total
includes taxes & fees
2 Jan - 3 Jan 2026
Home2 Suites by Hilton Houston Medical Center, TX
Desk, laptop workspace, iron/ironing board, cots/infant beds
Residence Inn by Marriott Houston Medical Center/NRG Park

Residence Inn by Marriott Houston Medical Center/NRG Park

Residence Inn by Marriott Houston Medical Center/NRG Park
3.0 star property
Texas Medical Center, 2.1 km from MD Anderson Cancer Center
9.4 out of 10, Exceptional, (505)
"Spacious, clean room and nice complementary breakfast "
United States
Karen
The price is ฿4,447
฿5,202 total
includes taxes & fees
31 Dec - 1 Jan 2026
Residence Inn by Marriott Houston Medical Center/NRG Park
Reception
InterContinental Houston by IHG

InterContinental Houston by IHG

InterContinental Houston by IHG
4.0 star property
Texas Medical Center, 0.7 km from MD Anderson Cancer Center
9.2 out of 10, Wonderful, (1001)
"Very clean room very polite staff"
United States
David
The price is ฿4,561
฿5,958 total
includes taxes & fees
29 Dec - 30 Dec
InterContinental Houston by IHG
Outdoor pool, free pool cabanas, pool umbrellas
The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District
4.0 star property
Texas Medical Center, 0.4 km from MD Anderson Cancer Center
9.2 out of 10, Wonderful, (1027)
"Excellent breakfast and bar"
United States
Misty
The price is ฿4,017
฿5,000 total
includes taxes & fees
28 Dec - 29 Dec
The Westin Houston Medical Center/Museum District
Lobby
Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center
3.0 star property
Texas Medical Center, 1.3 km from MD Anderson Cancer Center
9.2 out of 10, Wonderful, (2203)
"Comfortable room and nice breakfast in close proximity to Houston’s medical center. "
United States
Stephen
The price is ฿3,407
฿4,007 total
includes taxes & fees
29 Dec - 30 Dec
Hyatt Place Houston Medical Center
Lobby
Hyatt House Houston Medical Center

Hyatt House Houston Medical Center

Hyatt House Houston Medical Center
3.0 star property
Texas Medical Center, 1.3 km from MD Anderson Cancer Center
9.2 out of 10, Wonderful, (1206)
"We were here for a rugby tournament and the staff kept up with everything very well"
United States
Jessica Lynn
The price is ฿3,407
฿4,007 total
includes taxes & fees
29 Dec - 30 Dec
Hyatt House Houston Medical Center
Outdoor pool, pool loungers
Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton
4.0 star property
Texas Medical Center, 0.9 km from MD Anderson Cancer Center
9.0 out of 10, Wonderful, (3614)
"Cute hotel, very clean and friendly staff. We enjoyed our stay!"
United States
Alison
The price is ฿4,051
฿4,740 total
includes taxes & fees
18 Jan - 19 Jan 2026
Blossom Hotel Houston, Curio Collection by Hilton
Lobby
Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District
4.0 star property
Texas Medical Center, 0.4 km from MD Anderson Cancer Center
9.0 out of 10, Wonderful, (1001)
"Comfortable bed, very clean, very good food, quite, friendly stuff and hotel shuttle works easy."
United States
Elena
The price is ฿4,447
฿6,192 total
includes taxes & fees
3 Jan - 4 Jan 2026
Houston Marriott Medical Center/Museum District
Exterior
SpringHill Suites Houston Medical Center/NRG Park

SpringHill Suites Houston Medical Center/NRG Park

SpringHill Suites Houston Medical Center/NRG Park
3.0 star property
Astrodome, 1.9 km from MD Anderson Cancer Center
9.0 out of 10, Wonderful, (1002)
"Very clean and great breakfast "
United States
Saul
The price is ฿3,143
฿3,677 total
includes taxes & fees
1 Jan - 2 Jan 2026
SpringHill Suites Houston Medical Center/NRG Park
Premium bedding, pillow-top beds, minibar, in-room safe
Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District
4.5 star property
2 km from MD Anderson Cancer Center
9.0 out of 10, Wonderful, (1867)
"The staff made the stay worthwhile! Service was incredible and everyone was helpful and friendly. "
United States
lule
Hotel Zaza Houston Museum District
Exterior
Staybridge Suites Houston - Medical Center by IHG

Staybridge Suites Houston - Medical Center by IHG

Staybridge Suites Houston - Medical Center by IHG
3.0 star property
3 km from MD Anderson Cancer Center
9.0 out of 10, Wonderful, (817)
"The hotel is an excellent place to stay. Love the staff, cleanliness, parking. The social time is unique and breakfast was great. "
United States
Joseph
The price is ฿3,667
฿4,290 total
includes taxes & fees
26 Jan - 27 Jan 2026
Staybridge Suites Houston - Medical Center by IHG
Outdoor pool, pool umbrellas
Courtyard by Marriott Houston Medical Center/NRG Park

Courtyard by Marriott Houston Medical Center/NRG Park

Courtyard by Marriott Houston Medical Center/NRG Park
3.0 star property
2 km from MD Anderson Cancer Center
8.6 out of 10, Excellent, (1001)
"Great place to stay. "
United States
Tomi-Jayne
The price is ฿3,387
฿4,004 total
includes taxes & fees
4 Jan - 5 Jan 2026
Courtyard by Marriott Houston Medical Center/NRG Park
Lobby
Comfort Suites Houston near Medical Center- NRG Stadium

Comfort Suites Houston near Medical Center- NRG Stadium

Comfort Suites Houston near Medical Center- NRG Stadium
2.5 star property
2.8 km from MD Anderson Cancer Center
8.6 out of 10, Excellent, (1003)
"Clean room, helpful staff and good location to hospital."
United States
George
The price is ฿2,716
฿3,177 total
includes taxes & fees
28 Dec - 29 Dec
Comfort Suites Houston near Medical Center- NRG Stadium
Pool
Scottish Inns & Suites at NRG Park

Scottish Inns & Suites at NRG Park

Scottish Inns & Suites at NRG Park
2.5 star property
Astrodome, 2.9 km from MD Anderson Cancer Center
8.6 out of 10, Excellent, (414)
"The staff very friendly and accommodating "
United States
Timothy
The price is ฿2,486
฿2,908 total
includes taxes & fees
28 Dec - 29 Dec
Scottish Inns & Suites at NRG Park
Sun deck
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center
4.5 star property
0.6 km from MD Anderson Cancer Center
8.4 out of 10, Very good, (1788)
"The hotel was great and convenient. Easy check in an check out. Will definitely stay again. "
United States
Allison
The price is ฿2,714
฿3,211 total
includes taxes & fees
3 Jan - 4 Jan 2026
Hilton Houston Plaza/Medical Center
Daily buffet breakfast for a fee
DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites
4.0 star property
Texas Medical Center, 0.7 km from MD Anderson Cancer Center
8.4 out of 10, Very good, (479)
"Solid hotel and amenities"
United States
Kenneth
The price is ฿3,455
฿4,043 total
includes taxes & fees
23 Jan - 24 Jan 2026
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Bar (on property)
Hotel Ylem

Hotel Ylem

Hotel Ylem
3.5 star property
2.4 km from MD Anderson Cancer Center
8.4 out of 10, Very good, (2487)
"Good clean room, affordable rate. Would stay again."
United States
Bradford
Hotel Ylem
Free daily buffet breakfast
Hampton Inn & Suites Houston Medical Center NRG Park

Hampton Inn & Suites Houston Medical Center NRG Park

Hampton Inn & Suites Houston Medical Center NRG Park
2.5 star property
Texas Medical Center, 1.5 km from MD Anderson Cancer Center
8.2 out of 10, Very good, (1001)
"Breakfast was good the place was comfortable "
United States
Elton
The price is ฿3,032
฿3,564 total
includes taxes & fees
2 Jan - 3 Jan 2026
Hampton Inn & Suites Houston Medical Center NRG Park
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top MD Anderson Cancer Center Hotel Reviews

Hotel Ylem

Hotel Ylem

10/10 Excellent
"Great hotel, incredible folks working there, all around A+ experience "
Sharon 4-night trip
Posted 5 days ago
Hotel Ylem

Hotels near other MD Anderson Cancer Center attractions

Visitors enjoy a sunny day at Houston Zoo's picturesque landscape with a beautiful fountain in the heart of the Museum District

Houston Zoo

4.3/5 (2,621 reviews)
Feed a giraffe, catch a 4-D movie or cool off in the water park at this extraordinary zoo.
See properties
People enjoying a sunny day at Hermann Park in the Houston Museum District with fountains and lush greenery

Hermann Park

This expansive green space in the heart of the city offers places for exercising and relaxing, as well as a zoo and the Museum of Natural Science.
See properties

Frequently asked questions

What's the area like around MD Anderson Cancer Center?
MD Anderson Cancer Center is located in an area of Houston known for its top museums and popular theatre scene. If you're looking for a convenient place to stay, take a look at the 129 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay close to MD Anderson Cancer Center?
Adjacent to MD Anderson Cancer Center, The Westin Houston Medical Center/Museum District is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. Other good options close by include Blossom Hotel Houston, Curio Collection by Hilton and Hilton Houston Plaza/Medical Center.
How many hotels can I expect to find close to MD Anderson Cancer Center?
Expedia has 129 hotels and other accommodation options within a mile from MD Anderson Cancer Center.
If I need to cancel the hotel reservation for my stay near MD Anderson Cancer Center, will I receive a refund?
Yes, you'll find most room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you might be able to cancel it and be given a refund within 24 hours of your booking. Add your dates and click on "Search", then you can use the "fully refundable" filter to view the best deals available near MD Anderson Cancer Center.
What can I see and do near MD Anderson Cancer Center?
You might want to spend some time browsing the exhibits at Houston Natural Science Museum, Houston Museum of Fine Arts or Menil Collection. NRG Park, 2209 Dowling Street and Eldorado Ballroom are landmarks that you won't want to miss. You can catch a show at Main Street Theater - Rice Village, Midtown Arts and Theater Center Houston and House of Blues Houston.
How can I get to MD Anderson Cancer Center?
You can take advantage of metro transport at TMC Transit Center, Dryden/TMC Station and Smith Lands Station. If you'd like to venture around the area nearby, consider renting a car to take in more sights.