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Our top choices for Lowcountry Estuarium hotels

Miscellaneous
Super 8 by Wyndham Port Royal/Beaufort

Super 8 by Wyndham Port Royal/Beaufort

Super 8 by Wyndham Port Royal/Beaufort
2.0 star property
2.3 km from Lowcountry Estuarium
6.0 out of 10, (906)
"The room could have been a little cleaner but all and all it was Great! "
United States
Gina
The price is ฿1,922
฿2,114 total
includes taxes & fees
11 Jan - 12 Jan 2026
Super 8 by Wyndham Port Royal/Beaufort
Free daily buffet breakfast
SpringHill Suites by Marriott Beaufort

SpringHill Suites by Marriott Beaufort

SpringHill Suites by Marriott Beaufort
2.5 star property
7 km from Lowcountry Estuarium
9.4 out of 10, Exceptional, (1027)
"The rooms were very clean and the staff was very friendly!"
United States
Lee
The price is ฿3,206
฿3,526 total
includes taxes & fees
27 Dec - 28 Dec
SpringHill Suites by Marriott Beaufort
Exterior
Best Western Sea Island Inn

Best Western Sea Island Inn

Best Western Sea Island Inn
2.5 star property
6.1 km from Lowcountry Estuarium
9.4 out of 10, Exceptional, (1002)
"Perfect spot!"
United States
Tricia
The price is ฿4,631
฿5,094 total
includes taxes & fees
2 Jan - 3 Jan 2026
Best Western Sea Island Inn
View from property
City Loft Hotel

City Loft Hotel

City Loft Hotel
3.5 star property
6.2 km from Lowcountry Estuarium
9.4 out of 10, Exceptional, (759)
"Great place to stay in city center Beaufort. Easy free parking, friendly staff, comfy mattresses, nice bathroom and shower. Location was perfect for walking to shops and restaurants."
United States
Laura
The price is ฿4,443
฿4,887 total
includes taxes & fees
29 Dec - 30 Dec
City Loft Hotel
Premium bedding, individually decorated, individually furnished
Beaufort Inn

Beaufort Inn

Beaufort Inn
3.5 star property
6.2 km from Lowcountry Estuarium
9.0 out of 10, Wonderful, (1004)
"Charming historic inn. Comfortable and welcoming. A brief walk to the main shopping/eating section of town. Easy parking provided. Excellent light breakfast. Well worth the price."
United States
George
The price is ฿4,777
฿5,739 total
includes taxes & fees
24 Dec - 25 Dec
Beaufort Inn
Snack bar
Tru by Hilton Beaufort, SC

Tru by Hilton Beaufort, SC

Tru by Hilton Beaufort, SC
2.5 star property
7.5 km from Lowcountry Estuarium
9.0 out of 10, Wonderful, (711)
"Awesome stay!!!"
United States
Michael
The price is ฿2,936
฿3,230 total
includes taxes & fees
3 Jan - 4 Jan 2026
Tru by Hilton Beaufort, SC
Premier Room | Egyptian cotton sheets, premium bedding, pillow-top beds
The Emerald Boutique Stays

The Emerald Boutique Stays

The Emerald Boutique Stays
2.5 star property
6.4 km from Lowcountry Estuarium
9.2 out of 10, Wonderful, (220)
"Close to downtown shopping and restaurants. Nice room and helpful staff."
United States
Jeffrey
The price is ฿4,015
฿4,417 total
includes taxes & fees
24 Dec - 25 Dec
The Emerald Boutique Stays
Exterior
607 Bay Inn Downtown Beaufort

607 Bay Inn Downtown Beaufort

607 Bay Inn Downtown Beaufort
2.5 star property
6.2 km from Lowcountry Estuarium
9.6 out of 10, Exceptional, (90)
"Great Inn! Location, view, cleanliness, friendly staff!"
United States
Nicole
607 Bay Inn Downtown Beaufort
Exterior
Rhett House Inn

Rhett House Inn

Rhett House Inn
4.0 star property
6.2 km from Lowcountry Estuarium
9.2 out of 10, Wonderful, (643)
"What a lovely stay. Beautiful, clean and friendly staff made this stay wonderful. Will stay again while in Beaufort."
United States
REBECCA
The price is ฿4,576
฿6,040 total
includes taxes & fees
3 Jan - 4 Jan 2026
Rhett House Inn
Porch
Circa 1785

Circa 1785

Circa 1785
4.0 star property
6.9 km from Lowcountry Estuarium
9.6 out of 10, Exceptional, (137)
"Our room (#4) was FABULOUS. Huge with great bathroom and comfy bed and linens. Did not want to leave. 😫"
United States
Jill
The price is ฿4,006
฿4,406 total
includes taxes & fees
24 Dec - 25 Dec
Circa 1785
Balcony
Anchorage 1770

Anchorage 1770

Anchorage 1770
5.0 star property
6.2 km from Lowcountry Estuarium
9.2 out of 10, Wonderful, (218)
"Great property at a wonderful location."
United States
Dave
Anchorage 1770
Outdoor pool
Home2 Suites BY Hilton Beaufort, SC

Home2 Suites BY Hilton Beaufort, SC

Home2 Suites BY Hilton Beaufort, SC
3.0 star property
7.6 km from Lowcountry Estuarium
9.2 out of 10, Wonderful, (722)
"Room was spotless and beds comfortable"
United States
Judy
The price is ฿3,390
฿3,729 total
includes taxes & fees
3 Jan - 4 Jan 2026
Home2 Suites BY Hilton Beaufort, SC
Terrace/patio
Holiday Inn Hotel & Suites Beaufort at Highway 21 by IHG

Holiday Inn Hotel & Suites Beaufort at Highway 21 by IHG

Holiday Inn Hotel & Suites Beaufort at Highway 21 by IHG
3.0 star property
7.1 km from Lowcountry Estuarium
8.2 out of 10, Very good, (1003)
"Stayed here about 4 times and each time room has been clean especially the bathroom. Staff is very friendly and professional."
United States
John
The price is ฿2,895
฿3,184 total
includes taxes & fees
15 Jan - 16 Jan 2026
Holiday Inn Hotel & Suites Beaufort at Highway 21 by IHG
Reception
Hampton Inn Beaufort

Hampton Inn Beaufort

Hampton Inn Beaufort
2.5 star property
6.8 km from Lowcountry Estuarium
8.4 out of 10, Very good, (1001)
"Room was spotless and staff very courtesy."
United States
Griselda
The price is ฿2,963
฿3,259 total
includes taxes & fees
30 Dec - 31 Dec
Hampton Inn Beaufort
Exterior
Hilton Garden Inn Beaufort

Hilton Garden Inn Beaufort

Hilton Garden Inn Beaufort
3.0 star property
7 km from Lowcountry Estuarium
8.4 out of 10, Very good, (1002)
"Good hotel"
United States
joshua
The price is ฿2,670
฿2,937 total
includes taxes & fees
3 Jan - 4 Jan 2026
Hilton Garden Inn Beaufort
View from property
Cuthbert House

Cuthbert House

Cuthbert House
4.5 star property
6.1 km from Lowcountry Estuarium
9.2 out of 10, Wonderful, (951)
"Excellent accommodations. Staff was very friendly & helpful. Will definitely come back. The Inn is beautiful. "
United States
Melanie
The price is ฿11,723
฿12,895 total
includes taxes & fees
6 Jan - 7 Jan 2026
Cuthbert House
Lobby lounge
Comfort Suites near MCAS Beaufort

Comfort Suites near MCAS Beaufort

Comfort Suites near MCAS Beaufort
2.5 star property
6.5 km from Lowcountry Estuarium
7.4 out of 10, Good, (1004)
"I felt safe and the room was very clean. I received great customer service "
United States
Tonya
The price is ฿2,798
฿3,251 total
includes taxes & fees
28 Dec - 29 Dec
Comfort Suites near MCAS Beaufort
Exterior
Country Inn & Suites by Radisson, Beaufort West, SC

Country Inn & Suites by Radisson, Beaufort West, SC

Country Inn & Suites by Radisson, Beaufort West, SC
2.5 star property
6.9 km from Lowcountry Estuarium
7.2 out of 10, Good, (1003)
"I enjoyed everything. Parking, breakfast, staff, and parking was good. "
United States
Deaven
The price is ฿2,806
฿3,086 total
includes taxes & fees
30 Dec - 31 Dec
Country Inn & Suites by Radisson, Beaufort West, SC
Exterior
Sleep Inn Beaufort near MCAS

Sleep Inn Beaufort near MCAS

Sleep Inn Beaufort near MCAS
2.5 star property
7 km from Lowcountry Estuarium
7.4 out of 10, Good, (1001)
"Overall i would stay here again."
United States
Joshua
The price is ฿2,619
฿2,881 total
includes taxes & fees
12 Jan - 13 Jan 2026
Sleep Inn Beaufort near MCAS
Room, 1 King Bed, Refrigerator & Microwave | Desk, iron/ironing board, free WiFi, bed sheets
Oasis Inn

Oasis Inn

Oasis Inn
2.5 star property
7 km from Lowcountry Estuarium
7.4 out of 10, Good, (596)
"Fantastic stay. The staff was very friendly and helpful and the rooms were what I needed. Thank you "
United States
Chris
The price is ฿2,801
฿3,081 total
includes taxes & fees
25 Dec - 26 Dec
Oasis Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Lowcountry Estuarium Hotel Reviews

Fire Pit + Yard: Charming Port Royal Home!

Fire Pit + Yard: Charming Port Royal Home!

10/10 Excellent
"Loved staying at the Happy Little Cottage! It has all the amenities you could want. The neighborhood is very quoet. Our weather was lots of rain so we didn't get to use the firepit. We would love to stay there again the next time we come to Beaufort."
Virginia 3-night trip
Posted 3 months ago
Fire Pit + Yard: Charming Port Royal Home!

Hotels near other Lowcountry Estuarium attractions

Cypress Wetlands

3.8/5 (10 reviews)
Explore the great outdoors at Cypress Wetlands, a lovely green space in Port Royal. Stroll along the beautiful beaches or visit the shops in this family-friendly area.
See properties

The Sands

4.1/5 (55 reviews)
Why not spend a care-free afternoon at The Sands during your travels in Port Royal? Stroll along this family-friendly area's waterfront or simply enjoy its restaurants.
See properties

Frequently asked questions

What's the area like around Lowcountry Estuarium?
Lowcountry Estuarium is located in a family-friendly area of Port Royal known for its beautiful island views and major shopping area. If you're looking for a convenient place to stay, take a look at the 63 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay near Lowcountry Estuarium?
Located 1.4 mi (2.3 km) from Lowcountry Estuarium, Super 8 by Wyndham Port Royal/Beaufort is one of the top choices for your stay based on our traveller data.
How many hotels should I expect to find near Lowcountry Estuarium?
Expedia has 63 hotels and other accommodation options within a mile from Lowcountry Estuarium.
If I need to cancel the hotel reservation for my stay near Lowcountry Estuarium, will I receive a refund?
Yes, you'll find most hotel room reservations are refundable provided that you cancel prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, you might still have the option to cancel and be given a refund within a 24-hour period of booking. Add your dates and click on "Search", then use the filter option "fully refundable" to view the best options available near Lowcountry Estuarium.
What can I see and do near Lowcountry Estuarium?
You'll want to browse the exhibits at Parris Island Museum and Beaufort Museum. Beaufort National Cemetery, John Mark Verdier House and St. Helena's Episcopal Church are well-known local landmarks worth a visit. Get outside and spend some time strolling around Henry C. Chambers Waterfront Park, Cypress Wetlands and Port Royal Skateboard Park.