21c Museum Hotel Lexington offers modern comfort in downtown's heart. Travelers can enjoy breakfast and dinner at Lockbox restaurant, take advantage of dry cleaning and laundry services, and easily access nearby attractions like Rupp Arena and the University of Kentucky.
Located in Lexington, 21c Museum Hotel Lexington is in the city centre. Raven Run Nature Sanctuary and Triangle Park reflect the area's natural beauty and area attractions include Explorium and Downtown Arts Center. Looking to enjoy an event or a game? See what's going on at Kroger Field or Keeneland Racing Course. Spend some time exploring the area's activities, including golfing. Visit our Lexington travel guide
167 West Main Street, Lexington, KY, 40507
What's nearby
Lexington Opera House
5 min walk - 0.4 km
Lexington Convention Center
6 min walk - 0.6 km
Rupp Arena
8 min walk - 0.7 km
University of Kentucky
14 min walk - 1.2 km
Transylvania University
6 min walk - 0.6 km
Getting around
Lexington, KY (LEX-Blue Grass)
14 min drive
Restaurants
McCarthy's Irish Bar
1 min walk
Bluegrass Tavern
2 min walk
Belle's Cocktail House
2 min walk
Stagger Inn
2 min walk
Dudley's On Short
2 min walk
About this property
21c Museum Hotel Lexington
Upscale hotel near University of Kentucky
Take advantage of dry cleaning/laundry services, a bar and a 24-hour gym at 21c Museum Hotel Lexington. The on-site restaurant, Lockbox, offers breakfast and dinner. Free in-room WiFi and a 24-hour business centre are available to all guests.
Other perks include:
Valet parking (surcharge), a lift and ATM/banking services
A banquet hall, a porter/bellboy and smoke-free property
A 24-hour front desk, a front desk safe and a gift shop
Guest reviews speak highly of the dining options, helpful staff and location
Room features
All 88 rooms include comforts, such as premium bedding and laptop-friendly workspaces, in addition to perks, such as air conditioning and bathrobes. Guests reviews speak well of the clean rooms at the property.
Extra conveniences in all rooms include:
LED light bulbs and eco-friendly cleaning products
Bathrooms with designer toiletries and baths or showers
43-inch flat-screen TVs with premium channels
Daily housekeeping and phones
Awards and affiliations
Eco-certified property
This property participates in Green Key Global – a program that measures the property's impact on one or more of the following: environment, community, cultural-heritage, the local economy.
Available in all rooms: Free WiFi and wired internet
Available in some public areas: Free WiFi and wired internet
Parking and transport
Valet parking on site (USD 30 per night; includes in/out privileges)
Limited on-site valet parking
Wheelchair-accessible parking available
Food and drink
A bar/lounge
A restaurant
Snack bar/deli
Restaurants on site
Lockbox
Things to do
24-hour gym
Family friendly
Laundry facilities
Snack bar/deli
Soundproofed rooms
Conveniences
24-hour front desk
ATM
Gift shop/newsstand
Laundry facilities
Luggage storage
Safe at front desk
Vending machine
Water dispenser
Guest services
Change of bedsheets (on request)
Change of towels on request
Concierge services
Dry cleaning/laundry service
Housekeeping (daily)
Porter/bellhop
Tour and ticket assistance
Business services
24-hour business centre
Meeting rooms
Accessibility
If you have requests for specific accessibility needs, please contact the property using the information on the reservation confirmation received after booking.
Assistive listening devices
Braille/raised signage
Handrails in stairways
Lift
Stair-free path to entrance
Well-lit path to entrance
Wheelchair accessible (may have limitations)
Wheelchair-accessible parking
Wheelchair-accessible path of travel
Wheelchair-accessible path to lift
More
15 floors
At least 80% lighting from LEDs
Ballroom
Banquet hall
Biodegradable coffee stirrers available
Biodegradable drinking straws available
Double-glazed windows
Local culture and ecosystem education
No plastic coffee stirrers
No plastic drinking straws
No plastic soft drink bottles
No plastic water bottles
Reusable cups
Reusable tableware
Smoke-free property
Room amenities
Bedroom
Blackout drapes
Premium bedding
Bathroom
Bathtub or shower
Designer toiletries
Dressing gowns
Hair dryer
Private bathroom
Slippers
Towels provided
Entertainment
43-inch flat-screen TV with premium cable channels
IPod dock
Food and drink
Espresso maker
Free bottled water
Limited room service
Minibar
More
Air conditioning
Cleaning products are eco-friendly
Connecting rooms available
Eco-friendly toiletries
Free local calls
Iron/ironing board
Laptop workspace
LED lighting
Phone
Safe
Soundproofed rooms
Water-efficient showers
Policies
Check-in
Check-in start time: 4 PM; check-in end time: anytime
Contactless check-in and check-out are available
Minimum check-in age - 21
Check-out
Check-out before 11 AM
Contactless check-out
Special check-in instructions
Front desk staff will greet guests on arrival at the property
Information provided by the property may be translated using automated translation tools
Access methods
Staffed front desk
Pets
Pets are allowed for an extra charge of USD 50 per accommodation, per stay
Service animals are welcome, and are exempt from fees
Welcoming dogs and cats only
2 total (up to 23 kg per pet)
Children and extra beds
Children are welcome
Rollaway/extra beds are available for USD 30 per night.
Payment types at the property
Important information
Fees
You'll be asked to pay the following charges at the property. Fees may include applicable taxes:
Service fee: USD 5.00 per accommodation, per stay
We have included all charges provided to us by the property.
Optional extras
Valet parking fee: USD 30 per night (in/out privileges)
Pet fee: USD 50 per accommodation, per stay
Service animals are exempt from fees
Rollaway bed fee: USD 30 per night
The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.
You need to know
Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card, debit card or cash deposit may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards; cash is not accepted
Safety features at this property include a fire extinguisher
This property affirms that it follows the cleaning and disinfection practices of ALLSAFE (Accor Hotels)
We should mention
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)
Property is also known as
21c Museum Hotel Lexington
21c Museum Lexington MGallery
Hotel 21c Museum Hotel Lexington - MGallery Lexington
Lexington 21c Museum Hotel Lexington - MGallery Hotel
Hotel 21c Museum Hotel Lexington - MGallery
21c Museum Hotel Lexington MGallery
21c Museum Hotel Lexington - MGallery Lexington
21c Museum Hotel MGallery
21c Museum MGallery
21c Museum Hotel Lexington
21c Museum Lexington Lexington
21c Museum Hotel Lexington Hotel
21c Museum Hotel Lexington MGallery
21c Museum Hotel Lexington Lexington
21c Museum Hotel Lexington Hotel Lexington
Frequently asked questions
Is 21c Museum Hotel Lexington pet-friendly?
Yes, this hotel allows cats and dogs (limit 2 total) with a maximum weight of up to 23 kg per pet. There's a fee of USD 50 per accommodation, per stay. Service animals are exempt from fees.
How much does it cost to stay at 21c Museum Hotel Lexington?
As of 9 Mar 2026, prices found for a 1-night stay for 2 adults at 21c Museum Hotel Lexington on 15 Mar 2026 start from ฿4,852, excluding taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.
How much is parking at 21c Museum Hotel Lexington?
Valet parking is available for USD 30 per night.
What time is check-in at 21c Museum Hotel Lexington?
Check-in start time: 4 PM; check-in end time: anytime.
What time is check-out at 21c Museum Hotel Lexington?
Checkout is at 11 AM.
Where is 21c Museum Hotel Lexington located?
Located in Downtown Lexington, this hotel is within 1 mi (2 km) of Lexington History Center and University of Kentucky. Lexington Public Library and Phoenix Park Dog Park are just steps away.
Can I cancel my reservation for free and receive a full refund?
Yes, this property offers free cancellation on selected room rates because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.
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Reviews
21c Museum Hotel Lexington Reviews
8.8
Excellent
All reviews shown are from real guest experiences. Only travellers who have booked a stay with us can submit a review. We verify reviews according to our guidelines and publish all reviews, positive or negative.More informationOpens in a new window
Great hotel in great location. Clean, modern, and artsy. Room was very comfortable and the shower was great, which is big for me. It had good water pressure with hot water. Check in and out was quick and easy.
The Lockbox was good for breakfast one day and dinner another. Location is good. Can walk to many bars and restaurants downtown. Hotel is just average in regards to the room. Lots of street noise until probably 3am and we were on the 11th floor.
We had a corner room with great views. It eas large and comfortable. Loved the sofa for reading. We loved the art. We had three meals at the Lockbox.
Dana
Stayed 2 nights in Sep 2025
6/10 Okay
Cari
29 Oct 2025
Liked: Staff & service
I thought the staff was nice. They were attentive. The hotel was quirky and fun, just needed to have a more detailed cleaning. There was trash in the corner of our room, and just had an overall feeling that it needed a deep clean. I'm glad we stayed there as it was a quick and easy walk to the opera house.
We love this hotel. We've stayed at three 21c Museum Hotel's so far - Lexington, Louisville, and Cincinnati - and this one is by far our favorite. Lovely rooms, nice view, and an easy walk to the best restaurants and bars in the city.
Great stay, super clean, friendly service, spacious room, comfy bed; walkable downtown location close to many restaurants. Hotel restaurant was delicious.