Search Hotels in Isle of Palms, Jacksonville
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Our top choices for Isle of Palms hotels
1. Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Residence Inn By Marriott Jacksonville - Mayo Clinic AreaIsle of Palms
9.6 out of 10, Exceptional, (599 reviews)
"Great stay"
Michaelanne
The price is ฿4,568
฿5,185 total
includes taxes & fees
18 Oct - 19 Oct
2. Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG
Holiday Inn Express & Suites Jacksonville SE- Med Ctr Area by IHG3.9 km from Isle of Palms
9.0 out of 10, Wonderful, (1,008 reviews)
"clean rooms and great location!"
Jami
The price is ฿3,095
฿3,513 total
includes taxes & fees
18 Oct - 19 Oct
3. TownePlace Suites by Marriott Jacksonville East
TownePlace Suites by Marriott Jacksonville East3 km from Isle of Palms
9.2 out of 10, Wonderful, (658 reviews)
"Great location close to the beach. Super well maintained facility. Everything was great!"
gregory
The price is ฿4,143
฿4,703 total
includes taxes & fees
18 Oct - 19 Oct
4. Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic
Hampton Inn & Suites Jacksonville - Beach Blvd/Mayo Clinic3 km from Isle of Palms
9.0 out of 10, Wonderful, (1,000 reviews)
"Great place to stay."
Patsy
The price is ฿3,643
฿4,135 total
includes taxes & fees
11 Oct - 12 Oct
5. Hyatt Place Jacksonville / St. Johns Town Center
Hyatt Place Jacksonville / St. Johns Town Center9.7 km from Isle of Palms
9.2 out of 10, Wonderful, (1,164 reviews)
"Great staff, great breakfast, and very clean."
Marty
The price is ฿4,233
฿4,805 total
includes taxes & fees
4 Oct - 5 Oct
6. Margaritaville Jacksonville Beach
Margaritaville Jacksonville BeachOceanfront, 4.6 km from Isle of Palms
9.0 out of 10, Wonderful, (4,478 reviews)
"Enjoyed our overnight stay"
Melissa
The price is ฿4,967
฿5,637 total
includes taxes & fees
20 Sept - 21 Sept
7. Hilton Jacksonville at Mayo Clinic near Beaches
Hilton Jacksonville at Mayo Clinic near Beaches2.1 km from Isle of Palms
9.4 out of 10, Exceptional, (355 reviews)
"Excellent hotel and staff."
Kristen
The price is ฿5,594
฿6,349 total
includes taxes & fees
17 Oct - 18 Oct
8. Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass8.7 km from Isle of Palms
9.2 out of 10, Wonderful, (1,004 reviews)
"Family of 5 stayed comfortably!
Very accommodating and friendly!
Room was clean, pool was also fun!"
Brooke
The price is ฿3,921
฿4,371 total
includes taxes & fees
19 Oct - 20 Oct
9. Best Western Oceanfront
Best Western OceanfrontOceanfront, 4.4 km from Isle of Palms
9.0 out of 10, Wonderful, (1,001 reviews)
"The location was great."
Shawna
The price is ฿4,343
฿4,929 total
includes taxes & fees
20 Sept - 21 Sept
10. Holiday Inn Jacksonville E 295 Baymeadows by IHG
Holiday Inn Jacksonville E 295 Baymeadows by IHG9.8 km from Isle of Palms
8.6 out of 10, Excellent, (999 reviews)
"Great Hotel"
Josh
The price is ฿2,762
฿3,135 total
includes taxes & fees
18 Oct - 19 Oct
11. Sheraton Jacksonville Hotel
Sheraton Jacksonville Hotel10.7 km from Isle of Palms
9.2 out of 10, Wonderful, (1,002 reviews)
"Good location"
Jose
The price is ฿4,392
฿4,985 total
includes taxes & fees
20 Sept - 21 Sept
12. Holiday Inn Express & Suites Jacksonville - Town Center by IHG
Holiday Inn Express & Suites Jacksonville - Town Center by IHG8.7 km from Isle of Palms
9.6 out of 10, Exceptional, (1,000 reviews)
"good rooms, good shower, great breakfast. free parking, great location. 10 minutes from Mayo Clinic."
Ian
The price is ฿4,271
฿4,848 total
includes taxes & fees
20 Sept - 21 Sept
13. Element by Marriott Jacksonville Beach
Element by Marriott Jacksonville BeachOceanfront, 4.2 km from Isle of Palms
9.6 out of 10, Exceptional, (584 reviews)
"Nice lodging a block from the beach. Great food nearby."
Nick
The price is ฿5,058
฿5,741 total
includes taxes & fees
1 Oct - 2 Oct
14. Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area3.7 km from Isle of Palms
9.0 out of 10, Wonderful, (1,229 reviews)
"Just wish the hotel have a restaurant or a bar."
Hollye
The price is ฿3,932
฿4,463 total
includes taxes & fees
11 Oct - 12 Oct
15. Hyatt Studios Jacksonville/St Johns Town Center
Hyatt Studios Jacksonville/St Johns Town Center8.9 km from Isle of Palms
9.4 out of 10, Exceptional, (211 reviews)
"Very nice stay, they have grab and go breakfast as complimentary."
Phi
The price is ฿3,661
฿4,155 total
includes taxes & fees
3 Oct - 4 Oct
16. Tru By Hilton Jacksonville St Johns Town Center
Tru By Hilton Jacksonville St Johns Town Center9.7 km from Isle of Palms
9.2 out of 10, Wonderful, (956 reviews)
"Everything was clean and well maintained. The breakfast was great as well."
Jami
The price is ฿3,643
฿4,135 total
includes taxes & fees
20 Sept - 21 Sept
17. Four Points by Sheraton Jacksonville Beachfront
Four Points by Sheraton Jacksonville BeachfrontOceanfront, 4.3 km from Isle of Palms
9.0 out of 10, Wonderful, (1,007 reviews)
"Awesome stay"
Susan
The price is ฿5,912
฿6,710 total
includes taxes & fees
4 Oct - 5 Oct
18. Homewood Suites by Hilton Jacksonville-South/St. Johns Ctr.
Homewood Suites by Hilton Jacksonville-South/St. Johns Ctr.9.1 km from Isle of Palms
8.6 out of 10, Excellent, (1,001 reviews)
"The room was very clean and I really enjoyed my stay and I look forward to future stays at this loc"
Eddie
The price is ฿3,793
฿4,305 total
includes taxes & fees
18 Oct - 19 Oct
19. SpringHill Suites by Marriott Jacksonville Baymeadows
SpringHill Suites by Marriott Jacksonville Baymeadows14.2 km from Isle of Palms
9.0 out of 10, Wonderful, (991 reviews)
"Great location safe feeling, super clean and comfortable rooms"
Thereska
The price is ฿3,627
฿4,117 total
includes taxes & fees
20 Sept - 21 Sept
20. Springhill Suites By Marriott Jacksonville Beach Oceanfront
Springhill Suites By Marriott Jacksonville Beach OceanfrontOceanfront, 4.5 km from Isle of Palms
9.0 out of 10, Wonderful, (799 reviews)
"Beautiful room with a view. Great location and great restaurant on site!"
Laura
The price is ฿5,629
฿6,389 total
includes taxes & fees
4 Oct - 5 Oct
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Isle of Palms
Find the best Isle of Palms areas for the activities you enjoy most.
Photo by Ryan Ketterman
Open Photo by Ryan Ketterman
Downtown Jacksonville
The picturesque St. Johns River meanders through the center of this hub of skyscrapers, cultural landmarks and exciting nightlife.
Amelia City
While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.
Oceanfront
While visiting Oceanfront, you might make a stop by sights like Oceanfront Park and Northeast Florida Beaches.
Southside
If you're spending some time in Southside, St. Johns Town Center and Orange Park Place Shopping Center are top sights worth seeing.
Sawgrass
Beaches and riverfront are just a few things travellers like about Sawgrass. A stop by Mickler Beach is also recommended if you've got time to explore the area.