Search Hotels in Isle of Palms, Jacksonville

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Our top choices for Isle of Palms hotels

Reception
Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area

Residence Inn By Marriott Jacksonville - Mayo Clinic Area
3.0 star property
Isle of Palms
9.4 out of 10, Exceptional, (447)
"Great facility to stay."
United States
Gary
The price is ฿5,245
฿5,953 total
includes taxes & fees
30 Dec - 31 Dec
Residence Inn By Marriott Jacksonville - Mayo Clinic Area
Property amenity
Sheraton Jacksonville Hotel

Sheraton Jacksonville Hotel

Sheraton Jacksonville Hotel
4.0 star property
10.7 km from Isle of Palms
9.2 out of 10, Wonderful, (1008)
"Great stay and great customer service"
United States
Rebecca
The price is ฿3,123
฿3,545 total
includes taxes & fees
1 Jan - 2 Jan 2026
Sheraton Jacksonville Hotel
Restaurant
Extended Stay America Premier Suites - Jacksonville - Airport

Extended Stay America Premier Suites - Jacksonville - Airport

Extended Stay America Premier Suites - Jacksonville - Airport
2.5 star property
30.8 km from Isle of Palms
8.8 out of 10, Excellent, (140)
"Will stay here again "
United States
Jose
The price is ฿2,234
฿2,536 total
includes taxes & fees
4 Jan - 5 Jan 2026
Extended Stay America Premier Suites - Jacksonville - Airport
Free daily buffet breakfast
Hampton Inn & Suites Jacksonville South - Bartram Park

Hampton Inn & Suites Jacksonville South - Bartram Park

Hampton Inn & Suites Jacksonville South - Bartram Park
3.0 star property
18.5 km from Isle of Palms
9.0 out of 10, Wonderful, (1006)
"The staff was very friendly and helpful. "
United States
Carmelle
The price is ฿2,774
฿3,148 total
includes taxes & fees
10 Jan - 11 Jan 2026
Hampton Inn & Suites Jacksonville South - Bartram Park
On the beach, white sand, surfing, kayaking
Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach
2.5 star property
4.6 km from Isle of Palms
9.0 out of 10, Wonderful, (3443)
"Nice stay!"
United States
Mark
The price is ฿4,162
฿4,724 total
includes taxes & fees
4 Jan - 5 Jan 2026
Margaritaville Jacksonville Beach
Premium bedding, down duvets, desk, laptop workspace
SpringHill Suites by Marriott Jacksonville Baymeadows

SpringHill Suites by Marriott Jacksonville Baymeadows

SpringHill Suites by Marriott Jacksonville Baymeadows
3.0 star property
14.2 km from Isle of Palms
9.0 out of 10, Wonderful, (836)
"Very nice staff, clean, new bathrooms, excellent options at breakfast and great coffee. I would definitely stay here again "
United States
Candace
The price is ฿3,010
฿3,417 total
includes taxes & fees
5 Jan - 6 Jan 2026
SpringHill Suites by Marriott Jacksonville Baymeadows
Lobby lounge
Wyndham Garden Jacksonville

Wyndham Garden Jacksonville

Wyndham Garden Jacksonville
3.0 star property
15.5 km from Isle of Palms
7.8 out of 10, Good, (1788)
"Great staff, clean room and very convenient "
United States
David
The price is ฿2,163
฿2,455 total
includes taxes & fees
4 Jan - 5 Jan 2026
Wyndham Garden Jacksonville
Exterior
Holiday Inn Express Jacksonville - Blount Island by IHG

Holiday Inn Express Jacksonville - Blount Island by IHG

Holiday Inn Express Jacksonville - Blount Island by IHG
2.5 star property
20.3 km from Isle of Palms
8.6 out of 10, Excellent, (1001)
"Clean room and very friendly and helpful staff at this location.. we will definitely stay here again"
United States
Judy
The price is ฿2,855
฿3,241 total
includes taxes & fees
5 Jan - 6 Jan 2026
Holiday Inn Express Jacksonville - Blount Island by IHG
Sports facility
Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center

Hyatt Place Jacksonville / St. Johns Town Center
3.0 star property
9.7 km from Isle of Palms
9.2 out of 10, Wonderful, (1005)
"Breakfast was great. The selection was the best I have ever had in the US"
United States
Sandra
The price is ฿3,941
฿4,474 total
includes taxes & fees
9 Jan - 10 Jan 2026
Hyatt Place Jacksonville / St. Johns Town Center
Standard Double Room, 2 Double Beds, Smoking | Premium bedding, down duvets, in-room safe, blackout curtains
San Marco Inn East

San Marco Inn East

San Marco Inn East
3.0 star property
19.7 km from Isle of Palms
8.4 out of 10, Very good, (1300)
"Good stay, room clean "
United States
Alfonso
San Marco Inn East
Property amenity
Courtyard by Marriott Jacksonville Flagler Center

Courtyard by Marriott Jacksonville Flagler Center

Courtyard by Marriott Jacksonville Flagler Center
3.0 star property
17.8 km from Isle of Palms
8.8 out of 10, Excellent, (1002)
"Great hotel "
United States
Sandra
The price is ฿2,979
฿3,382 total
includes taxes & fees
4 Jan - 5 Jan 2026
Courtyard by Marriott Jacksonville Flagler Center
Exterior
Baymont by Wyndham Jacksonville/Butler Blvd

Baymont by Wyndham Jacksonville/Butler Blvd

Baymont by Wyndham Jacksonville/Butler Blvd
2.5 star property
16.4 km from Isle of Palms
8.2 out of 10, Very good, (1290)
"Rooms were clean staff Friendly "
United States
Ann
The price is ฿2,110
฿2,395 total
includes taxes & fees
11 Jan - 12 Jan 2026
Baymont by Wyndham Jacksonville/Butler Blvd
Lobby
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass

Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
3.0 star property
8.8 km from Isle of Palms
9.0 out of 10, Wonderful, (1006)
"Friendly staff, easy check-in super clean room and facility. Location is excellent as well."
United States
Anthony
The price is ฿3,561
฿3,970 total
includes taxes & fees
25 Jan - 26 Jan 2026
Hilton Garden Inn Jacksonville Ponte Vedra Sawgrass
Exterior
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area

Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
2.5 star property
3.7 km from Isle of Palms
9.0 out of 10, Wonderful, (1006)
"Good location for exploring Ponte Vedra and Jacksonville Beach areas."
United States
Julianne
The price is ฿3,785
฿4,296 total
includes taxes & fees
11 Jan - 12 Jan 2026
Hampton Inn Jacksonville/Ponte Vedra Beach-Mayo Clinic Area
Reception
Tru by Hilton Jacksonville South Mandarin

Tru by Hilton Jacksonville South Mandarin

Tru by Hilton Jacksonville South Mandarin
2.5 star property
21.6 km from Isle of Palms
9.0 out of 10, Wonderful, (1007)
"Excellent staff and hotel "
United States
Edward
The price is ฿2,774
฿3,148 total
includes taxes & fees
11 Jan - 12 Jan 2026
Tru by Hilton Jacksonville South Mandarin
Exterior
Holiday Inn Express & Suites Jacksonville Airport by IHG

Holiday Inn Express & Suites Jacksonville Airport by IHG

Holiday Inn Express & Suites Jacksonville Airport by IHG
2.5 star property
31.3 km from Isle of Palms
8.6 out of 10, Excellent, (1010)
"Clean room, great service, good breakfast options."
United States
KRITI KUMAR
The price is ฿3,228
฿3,663 total
includes taxes & fees
30 Dec - 31 Dec
Holiday Inn Express & Suites Jacksonville Airport by IHG
Daily buffet breakfast (USD 26.95 per person)
Hyatt Regency Jacksonville

Hyatt Regency Jacksonville

Hyatt Regency Jacksonville
4.0 star property
22.3 km from Isle of Palms
9.0 out of 10, Wonderful, (1405)
"Great stay "
United States
terria
The price is ฿5,276
฿6,048 total
includes taxes & fees
1 Jan - 2 Jan 2026
Hyatt Regency Jacksonville
Exterior
Fairfield Inn & Suites by Marriott Jacksonville Beach

Fairfield Inn & Suites by Marriott Jacksonville Beach

Fairfield Inn & Suites by Marriott Jacksonville Beach
2.5 star property
5 km from Isle of Palms
8.6 out of 10, Excellent, (892)
"Great place to stay highly recommend it"
United States
Taryn
The price is ฿3,414
฿3,875 total
includes taxes & fees
4 Jan - 5 Jan 2026
Fairfield Inn & Suites by Marriott Jacksonville Beach
Lobby
Hyatt Place Jacksonville Airport

Hyatt Place Jacksonville Airport

Hyatt Place Jacksonville Airport
3.0 star property
31.1 km from Isle of Palms
9.0 out of 10, Wonderful, (2308)
"Nice and clean hotel, good breakfast, had a comfortable stay."
United States
Krishna
The price is ฿3,414
฿3,875 total
includes taxes & fees
5 Jan - 6 Jan 2026
Hyatt Place Jacksonville Airport
Outdoor pool, open 7:00 AM to 7:00 PM, pool umbrellas, pool loungers
One Ocean Resort and Spa

One Ocean Resort and Spa

One Ocean Resort and Spa
4.5 star property
6.7 km from Isle of Palms
8.8 out of 10, Excellent, (1002)
"Need to rethink having guests in middle of this major renovation. Refresh definitely needed. Wouldn’t stay here again until renovation is complete. Staff was accommodating. "
United States
karen
The price is ฿4,944
฿6,613 total
includes taxes & fees
11 Jan - 12 Jan 2026
One Ocean Resort and Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Isle of Palms

Find the best Isle of Palms areas for the activities you enjoy most.
Photo by Ryan Ketterman
Open Photo by Ryan Ketterman

Downtown Jacksonville

The picturesque St. Johns River meanders through the center of this hub of skyscrapers, cultural landmarks and exciting nightlife.

Amelia City

While visiting Amelia City, you might make a stop by sights like American Beach and Fernandina Beach.

Southside

If you're spending some time in Southside, St. Johns Town Center and Orange Park Place Shopping Center are top sights worth seeing.

Sawgrass

Beaches and riverfront are just a few things travellers like about Sawgrass. A stop by Mickler Beach is also recommended if you've got time to explore the area.

Cummer Museum of Art and Gardens featuring art and interior views as well as a couple
Photo by Visit Jacksonville
Open Photo by Visit Jacksonville

Northwest

While visiting Northwest, you might make a stop by sights like Cummer Museum of Art and Gardens and Jacksonville-Baldwin Rail Trail.

Top Isle of Palms Hotel Reviews

Margaritaville Jacksonville Beach

Margaritaville Jacksonville Beach

10/10 Excellent
"Yes !! Beautiful room , staff was amazing!! But the shower only got warm for a minute then cold again ! Totally frustrating "
Timothy 1-night trip
Posted 4 days ago
Margaritaville Jacksonville Beach

Frequently asked questions

What is Isle of Palms like?
Travellers are sure to enjoy a stay in Jacksonville Beach's Isle of Palms neighbourhood.
What's a favourite hotel to stay in Isle of Palms?
Based on Expedia customer reviews, Residence Inn By Marriott Jacksonville - Mayo Clinic Area is the highest ranked property in Isle of Palms. This hotel offers free breakfast and an outdoor pool.
How many hotels should I expect to find in Isle of Palms?
Expedia has 39 hotels and other accommodation options in Isle of Palms to choose from, making this an ideal home base for exploring the greater Jacksonville Beach area.
If I need to cancel my hotel reservation in Isle of Palms, will I receive a refund?
Yes! You'll find that most hotel room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your check-in date. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of booking. Enter your dates, click on "Search", then you can use the "fully refundable" filter to view the best deals available in Isle of Palms.
What is there to do in this Jacksonville Beach neighbourhood?
A few places to visit in the area around Isle of Palms include Adventure Landing, Cradle Creek Preserve and Jacksonville Beach Golf Club. While you're out sightseeing in Jacksonville Beach, make sure that you visit other sights such as Windsor Parke Golf Club or Players by the Sea.