Find hotels in Greencastle, MO from ฿2,269

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Our top choices for Greencastle hotels

Holiday Inn Express & Suites Kirksville - University Area by IHG

Holiday Inn Express & Suites Kirksville - University Area by IHG
2.5 star property
Kirksville
9.2 out of 10, Wonderful, (511)
"Excellent service and stay"
United States
Taylor
The price is ฿3,667
฿4,156 total
includes taxes & fees
11 Jan - 12 Jan 2026
Holiday Inn Express & Suites Kirksville - University Area by IHG

Super 8 by Wyndham Kirksville-University Area

Super 8 by Wyndham Kirksville-University Area
2.5 star property
Kirksville
9.0 out of 10, Wonderful, (152)
"The rooms were clean and the breakfast bar is outstanding staff was very friendly and helpful "
United States
Bill
The price is ฿2,020
฿2,269 total
includes taxes & fees
1 Jan - 2 Jan 2026
Super 8 by Wyndham Kirksville-University Area

Hampton Inn Kirksville

Hampton Inn Kirksville
2.5 star property
Kirksville
9.2 out of 10, Wonderful, (574)
"Better than a typical hotel, premium bedding, great lobby space for families to gather."
United States
Lynn
The price is ฿3,797
฿4,303 total
includes taxes & fees
2 Jan - 3 Jan 2026
Hampton Inn Kirksville

Knights Inn Kirksville

Knights Inn Kirksville
1.5 star property
Kirksville
7.2 out of 10, Good, (250)
"Cozy and cool."
United States
Lois
The price is ฿2,113
฿2,374 total
includes taxes & fees
26 Dec - 27 Dec
Knights Inn Kirksville

Days Inn by Wyndham Kirksville

Days Inn by Wyndham Kirksville
2.0 star property
Kirksville
6.6 out of 10, (1000)
"Breakfast was great enjoyed the pool"
United States
Dara
The price is ฿2,024
฿2,273 total
includes taxes & fees
28 Dec - 29 Dec
Days Inn by Wyndham Kirksville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Greencastle Hotel Reviews

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Frequently asked questions

What's the best place for a stay in Greencastle?
Super 8 by Wyndham Kirksville-University Area, located 17.4 mi (27.9 km) from the heart of Greencastle, is a top choice for your stay, based on our traveller data. Other good options for your visit to the area are Hampton Inn Kirksville and Days Inn by Wyndham Kirksville. See all available top hotels, or vacation rentals in Greencastle.
If I need to cancel my hotel reservation in Greencastle, will I receive a refund?
Yes, the majority of hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Greencastle.
How is it to stay in Greencastle?
Visitors will definitely enjoy all that Greencastle has to offer. There are 46 hotels and other accommodation options in the surrounding area. Find out more about Greencastle.
What should I do while I'm visiting Greencastle?
Thousand Hills State Park is one of the places to visit in the surrounding area. Take a look at what more there is to see and do in Expedia's Greencastle guide.
What's the seasonal weather like in Greencastle?
The hottest months are usually July and August, with an average temperature of 23°C, while the coldest months are January and February, with an average of 0°C. The snowiest months in Greencastle are January, November, February and December, with each month seeing an average of 13 cm of snowfall.