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Our top choices for Grand Center hotels

Lobby
White House at Grand Central

White House at Grand Central

White House at Grand Central
4.0 star property
Grand Center
8.6 out of 10, Excellent, (124)
"Very clean and very friendly people "
United States
Mary
The price is ฿2,044
฿4,412 total
includes taxes & fees
19 Jan - 20 Jan 2026
White House at Grand Central
Terrace/patio
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton

Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
4.0 star property
Grand Center
8.8 out of 10, Excellent, (1039)
"Fun staff and a very cool hotel. Great room, too!"
United States
Christopher
The price is ฿3,744
฿4,415 total
includes taxes & fees
25 Dec - 26 Dec
Angad Arts Hotel St. Louis, Tapestry Collection by Hilton
Front of property
Grand Center Inn

Grand Center Inn

Grand Center Inn
3.0 star property
Grand Center
9.4 out of 10, Exceptional, (72)
"Great! "
United States
mike
The price is ฿5,622
฿6,630 total
includes taxes & fees
21 Dec - 22 Dec
Grand Center Inn
Lobby
Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch

Hyatt Regency St. Louis at The Arch
4.0 star property
Downtown St. Louis, 4.2 km from Grand Center
8.4 out of 10, Very good, (4028)
"Everything was great!"
United States
Kathryn
The price is ฿3,109
฿3,667 total
includes taxes & fees
21 Dec - 22 Dec
Hyatt Regency St. Louis at The Arch
Terrace/patio
Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood

Courtyard by Marriott St. Louis Brentwood
3.0 star property
9 km from Grand Center
9.4 out of 10, Exceptional, (838)
"Clean, would stay again."
United States
Eryka
The price is ฿3,177
฿3,897 total
includes taxes & fees
21 Dec - 22 Dec
Courtyard by Marriott St. Louis Brentwood
Reception
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham

Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
3.0 star property
23.3 km from Grand Center
8.0 out of 10, Very good, (1045)
"Everything was clean and friendly staff overall good experience "
United States
dennis
The price is ฿2,670
฿3,084 total
includes taxes & fees
22 Dec - 23 Dec
Heritage Inn & Suites St. Louis/Fenton, Trademark by Wyndham
Indoor pool, open 8:00 AM to 10:00 PM, pool loungers
La Quinta Inn & Suites by Wyndham St Louis Route 66

La Quinta Inn & Suites by Wyndham St Louis Route 66

La Quinta Inn & Suites by Wyndham St Louis Route 66
3.0 star property
18 km from Grand Center
8.0 out of 10, Very good, (1002)
"Nice Staff, Clean Rooms, Good Area!!"
United States
Keyaira
The price is ฿3,017
฿3,507 total
includes taxes & fees
5 Jan - 6 Jan 2026
La Quinta Inn & Suites by Wyndham St Louis Route 66
Free daily buffet breakfast
Tru By Hilton St. Louis Downtown

Tru By Hilton St. Louis Downtown

Tru By Hilton St. Louis Downtown
2.5 star property
Downtown West, 3.1 km from Grand Center
7.6 out of 10, Good, (594)
"Breakfast was delicious and room was comfy "
United States
Ronnesha
The price is ฿2,550
฿2,981 total
includes taxes & fees
4 Jan - 5 Jan 2026
Tru By Hilton St. Louis Downtown
Seasonal outdoor pool
Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa

Ameristar Casino Resort and Spa
4.5 star property
26.1 km from Grand Center
8.4 out of 10, Very good, (1007)
"Clean room, wonderful helpful pleasant staff, amenities, everything was great love staying here!"
United States
Robyn
The price is ฿4,779
฿6,106 total
includes taxes & fees
22 Dec - 23 Dec
Ameristar Casino Resort and Spa
Bar (on property)
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel

Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
4.0 star property
Downtown St. Louis, 3.7 km from Grand Center
8.8 out of 10, Excellent, (1158)
"Really enjoyed my stay! Highly recommend this place. It’s a vintage style hotel that is very well kept uo"
United States
Varun
The price is ฿2,516
฿2,992 total
includes taxes & fees
24 Dec - 25 Dec
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Lobby
Pear Tree Inn St. Louis Convention Center

Pear Tree Inn St. Louis Convention Center

Pear Tree Inn St. Louis Convention Center
3.0 star property
Downtown St. Louis, 3.9 km from Grand Center
9.0 out of 10, Wonderful, (1054)
"Was a lovely place to stay! Everyone was kind and friendly. "
United States
Shandee
The price is ฿2,952
฿3,452 total
includes taxes & fees
25 Dec - 26 Dec
Pear Tree Inn St. Louis Convention Center
Exterior
Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District

Country Inn & Suites by Radisson, St. Charles Historic District
2.5 star property
26.4 km from Grand Center
9.4 out of 10, Exceptional, (1002)
"Good stay."
United States
Steven
The price is ฿3,481
฿4,001 total
includes taxes & fees
11 Jan - 12 Jan 2026
Country Inn & Suites by Radisson, St. Charles Historic District
Exterior
Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay

Clayton Plaza Hotel & Extended Stay
3.5 star property
9.2 km from Grand Center
8.8 out of 10, Excellent, (3035)
"Clean room, good breakfast and good location "
United States
Martin
The price is ฿2,824
฿3,297 total
includes taxes & fees
21 Dec - 22 Dec
Clayton Plaza Hotel & Extended Stay
Indoor pool, open 6:00 AM to 10:00 PM, pool loungers
Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)

Hampton Inn St. Louis-Downtown (At the Gateway Arch)
2.5 star property
Downtown St. Louis, 4.1 km from Grand Center
8.8 out of 10, Excellent, (1180)
"Breakfast was great and this was my seventh year staying there."
United States
Derick
The price is ฿3,065
฿3,584 total
includes taxes & fees
28 Dec - 29 Dec
Hampton Inn St. Louis-Downtown (At the Gateway Arch)
Lobby
Fairfield Inn & Suites by Marriott St. Louis Downtown

Fairfield Inn & Suites by Marriott St. Louis Downtown

Fairfield Inn & Suites by Marriott St. Louis Downtown
2.5 star property
Downtown West, 2.2 km from Grand Center
9.2 out of 10, Wonderful, (1003)
"Breakfast menu was fresh and tasty. Will return in the future with more time to go to the national park!"
United States
Silvar
The price is ฿3,361
฿4,010 total
includes taxes & fees
28 Dec - 29 Dec
Fairfield Inn & Suites by Marriott St. Louis Downtown
Front of property – evening/night
Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis

Hollywood Casino & Hotel St. Louis
3.5 star property
24.9 km from Grand Center
8.4 out of 10, Very good, (2219)
"Front staff was very friendly and very helpful. Check-in and check out was smooth and very easy. "
United States
James
The price is ฿3,674
฿4,744 total
includes taxes & fees
18 Jan - 19 Jan 2026
Hollywood Casino & Hotel St. Louis
Lobby sitting area
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West

Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
3.0 star property
23.5 km from Grand Center
7.4 out of 10, Good, (1009)
"Clean lobby, super friendly staff, effortless check in. There’s even a small market with food and essentials right next to the check in desk. "
United States
Jen
The price is ฿2,239
฿2,597 total
includes taxes & fees
28 Dec - 29 Dec
Larkspur Landing Extended Stay Suites St. Louis Riverport - Airport West
Free daily continental breakfast
Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport

Wingate by Wyndham St. Louis Airport
2.5 star property
16.2 km from Grand Center
9.2 out of 10, Wonderful, (1507)
"The room was very clean and the staff was very helpful."
United States
John
The price is ฿3,390
฿3,992 total
includes taxes & fees
22 Dec - 23 Dec
Wingate by Wyndham St. Louis Airport
Property amenity
Moonrise Hotel

Moonrise Hotel

Moonrise Hotel
4.0 star property
6.1 km from Grand Center
9.0 out of 10, Wonderful, (1916)
"Clean rooms, good coffee and fresh muffins and friendly service."
United States
Colleen
The price is ฿3,538
฿4,208 total
includes taxes & fees
24 Dec - 25 Dec
Moonrise Hotel
Breakfast, lunch and dinner served
Live by Loews - St.Louis

Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis, 3.8 km from Grand Center
9.4 out of 10, Exceptional, (1106)
"Clean room! Staff were very helpful and nice! Room exceeded my expectations, food was great, friendly environment! Best hotel in St.Louis hands down!!!"
United States
Twoun
The price is ฿4,680
฿5,566 total
includes taxes & fees
21 Dec - 22 Dec
Live by Loews - St.Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Where to stay in Grand Center

Find the best Grand Center areas for the activities you enjoy most.

Downtown St. Louis

Gourmet restaurants beloved sports teams and top sights from Gateway Arch to Gateway Arch National Park – discover Downtown St. Louis, a destination also famous for its historic sites.

Clayton

Take time in Clayton to visit attractions like Chapel of St. Timothy And St. Titus, Concordia Seminary and Shaw Park Tennis Center. You might also appreciate the abundant dining options, and you can hop on the metro at Clayton Station to see more of the city.

St. Charles Historic District

St. Charles Historic District is known for its ample dining options, and you can make a stop by Historic Main Street and Missouri River while in the area.

Creve Coeur

Travellers come to Creve Coeur for its abundant dining options, and you can see top attractions like Creve Coeur Golf Club and Saint Louis Abbey while you're in town.

Central West End

Central West End

Enjoy this relaxed area, the ultimate destination for a lazy afternoon. Browse unique stores, admire artworks and sip coffee at sidewalk tables shaded by trees.

Top Grand Center Hotel Reviews

Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch

10/10 Excellent
"All is perfect except room cleanse "
BINIAM 3-night trip
Posted 3 days ago
Drury Plaza Hotel St. Louis at the Arch

Frequently asked questions

What's it like in Grand Center?
Grand Center is a neighbourhood that travellers like for its theatre scene and opera houses. Make sure that you visit St. Louis Symphony Orchestra and Fox Theater as part of your Grand Center travel plans.
Where is the best hotel for a stay in Grand Center?
Based on Expedia customer reviews, Grand Center Inn is the highest ranked property in Grand Center. This guest house offers free parking and private gardens. Another top choice in the area is Angad Arts Hotel St. Louis, Tapestry Collection by Hilton.
How many hotels will I find in Grand Center?
Expedia has 31 hotels and other accommodation options in Grand Center to choose from, making this an ideal home base for exploring the greater St. Louis area.
If I need to cancel my hotel reservation in Grand Center, will I receive a refund?
Yes! You'll find that most room reservations are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If your reservation is non-refundable, it might still be possible to cancel it and get a refund within a 24-hour period of booking. Enter your dates, click on "Search", then filter by "fully refundable" to view the best options available in Grand Center.
What are the top things to see and do in Grand Center?
While you're in Grand Center, you can catch a show at St. Louis Symphony Orchestra, Fox Theater and Grandel Theater. Powell Hall and Powell Symphony Hall are also a couple of places to visit in the neighbourhood. St. Louis Union Station and Gateway Arch are some popular places to visit in the area around Grand Center. While you're out sightseeing in St. Louis, make sure that you visit other sights such as Urban League St. Louis or Vaughn Cultural Center.