Matlacha Isles Travel Guide
Cape Coral
Visit Matlacha Isles
Things to do
Sunset Cruise Fort Myers Beach
฿1,600
per adult
100% of travellers recommend
Dolphin Wildlife Cruise Fort Myers Beach
฿2,133
per adult
100% of travellers recommend
Southwest Florida Sunset Sail
฿2,337
per adult
100% of travellers recommend
Parasailing Adventure on Fort Myers Beach (400 Foot Flight)
฿3,492
per adult
94% of travellers recommend
Dolphin and Shelling Cruise Tour at Fort Myers Beach
฿2,489
per adult
100% of travellers recommend
Top hotels in Matlacha Isles
Marriott Sanibel Harbour Resort & Spa
17260 Harbour Pointe Dr Fort Myers FL
The price is ฿6,964 per night from 4 Nov to 5 Nov
฿6,964
฿8,941 total
4 Nov - 5 Nov
includes taxes & fees
Stay at this spa resort in Fort Myers. Enjoy 3 outdoor pools, a full-service spa and 4 restaurants. Our guests praise the helpful staff and the property condition ...
Margaritaville Beach Resort Fort Myers
251 Crescent Street Fort Myers Beach FL
The price is ฿6,015 per night from 26 Oct to 27 Oct
฿6,015
฿8,393 total
26 Oct - 27 Oct
includes taxes & fees
Stay at this beach hotel in Fort Myers Beach. Enjoy free Wi-Fi, a full-service spa and 4 restaurants. Our guests praise the pool and the helpful staff in their ...
9/10 Wonderful! (2,684 reviews)
"Great atmosphere I love all the music"
Reviewed on 21 Oct 2026
The Lighthouse Resort Inn & Suites
1051 5th St Fort Myers Beach FL
The price is ฿3,520 per night from 10 Nov to 11 Nov
฿3,520
฿4,596 total
10 Nov - 11 Nov
includes taxes & fees
Stay at this hotel in Fort Myers Beach. Enjoy free Wi-Fi, free parking and 2 outdoor pools. Our guests praise the pool and the helpful staff in their reviews. ...
8.6/10 Excellent! (1,827 reviews)
"A nice “retro” hotel with easy access to the beach. The Tiki Bar was straight out of the early sixties - the only tell was the modern music they played. The beach was great, but we were there immediately after a hurricane passed through, so the water was turbid and there was loads of seaweed along ..."
Reviewed on 21 Oct 2026
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
1538 Cape Coral Pkwy E Cape Coral FL
The price is ฿3,394 per night from 15 Nov to 16 Nov
฿3,394
฿3,785 total
15 Nov - 16 Nov
includes taxes & fees
Stay at this business-friendly hotel in Cape Coral. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
9.4/10 Exceptional! (1,716 reviews)
"Normal, nada a destacar!!!"
Reviewed on 21 Oct 2026
Lani Kai Beachfront Resort
1400 Estero Blvd Fort Myers Beach FL
The price is ฿5,340 per night from 2 Nov to 3 Nov
฿5,340
฿6,703 total
2 Nov - 3 Nov
includes taxes & fees
Stay at this beach hotel in Fort Myers Beach. Enjoy free Wi-Fi, 3 restaurants and a beach locale. Popular attractions Key West Express and Estero Boulevard Beach ...
Sanibel Island Beach Resort
1231 Middle Gulf Dr Sanibel FL
The price is ฿6,012 per night from 22 Oct to 23 Oct
฿6,012
฿7,639 total
22 Oct - 23 Oct
includes taxes & fees
Stay at this beach hotel in Sanibel. Enjoy free Wi-Fi, free parking and a beach locale. Our guests praise the pool and the restaurant in their reviews. Popular ...
9.2/10 Wonderful! (2,374 reviews)
"Great resort. Great staff"
Reviewed on 21 Oct 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Matlacha Isles
Find the best Matlacha Isles areas for the activities you enjoy most.
Pelican
While visiting Pelican, you might make a stop by sights like Tarpon Point and Chabad Jewish Center.
Caloosahatchee
If you're spending some time in Caloosahatchee, Dolphin Marina and Cape Coral Yacht Club Beach are top sights worth seeing.
Hancock
While visiting Hancock, you might make a stop by sights like Four Mile Cove Ecological Preserve and Pine Island Shopping Center.
Yacht Club
While Yacht Club isn't home to many top sights, Cape Coral Yacht Club Beach and Dolphin Marina are some notable places to visit nearby.
Burnt Store
When in Burnt Store, you can plan a visit to Coral Oaks Golf Course and Burnt Store Marina, some noteworthy sights in the nearby area.
