Matlacha Isles Travel Guide
Cape Coral
Visit Matlacha Isles
Things to do
Southwest Florida Sunset Sail
฿2,300
per adult
100% of travellers recommend
Dolphin Wildlife Cruise Fort Myers Beach
฿2,099
per adult
100% of travellers recommend
Parasailing Adventure on Fort Myers Beach (400 Foot Flight)
฿3,436
per adult
94% of travellers recommend
Historic Walking Tour of Fort Myers
฿986
per adult
100% of travellers recommend
Tiki Pub Amazing Dolphin Eco Adventure
฿1,641
per adult
100% of travellers recommend
Top hotels in Matlacha Isles
Margaritaville Beach Resort Fort Myers
251 Crescent Street Fort Myers Beach FL
The price is ฿6,838 per night from 26 Jul to 27 Jul
฿6,838
฿9,289 total
26 Jul - 27 Jul
includes taxes & fees
Stay at this beach hotel in Fort Myers Beach. Enjoy free Wi-Fi, a full-service spa and 4 restaurants. Our guests praise the pool and the helpful staff in their ...
9/10 Wonderful! (2,287 reviews)
"The drinks at the fins up pool/bar sucked."
Reviewed on 3 Jul 2026
Lani Kai Beachfront Resort
1400 Estero Blvd Fort Myers Beach FL
Fully refundable
The price is ฿4,747 per night from 7 Jul to 8 Jul
฿4,747
฿6,033 total
7 Jul - 8 Jul
includes taxes & fees
Stay at this beach hotel in Fort Myers Beach. Enjoy free Wi-Fi, 3 restaurants and a beach locale. Popular attractions Key West Express and Estero Boulevard Beach ...
9/10 Wonderful! (1,696 reviews)
"It was the worst stay, the bed was not good, everything was just extremely uncomfortable and not clean. Had to sleep on the floor…"
Reviewed on 3 Jul 2026
Sanibel Island Beach Resort
1231 Middle Gulf Dr Sanibel FL
The price is ฿7,597 per night from 2 Aug to 3 Aug
฿7,597
฿9,300 total
2 Aug - 3 Aug
includes taxes & fees
Stay at this beach hotel in Sanibel. Enjoy free Wi-Fi, free parking and a beach locale. Our guests praise the pool and the restaurant in their reviews. Popular ...
9.2/10 Wonderful! (2,086 reviews)
"The room is very clean and updated. Staffs were friendly and prompt when asked for something extra for the room. Appreciate the text messages that we can communicate with staffs on the go."
Reviewed on 4 Jul 2026
Marriott Sanibel Harbour Resort & Spa
17260 Harbour Pointe Dr Fort Myers FL
The price is ฿6,343 per night from 5 Aug to 6 Aug
฿6,343
฿8,234 total
5 Aug - 6 Aug
includes taxes & fees
Stay at this spa resort in Fort Myers. Enjoy 3 outdoor pools, a full-service spa and 4 restaurants. Our guests praise the helpful staff and the property condition ...
8.6/10 Excellent! (1,006 reviews)
"The room was great. Pool maintained. Food DELICIOUS! However, there is no real beach on the property or within walking distance. Everything else was just fine. The staff were friendly and helpful."
Reviewed on 3 Jul 2026
Holiday Inn Express Cape Coral-Fort Myers Area by IHG
1538 Cape Coral Pkwy E Cape Coral FL
The price is ฿3,284 per night from 5 Aug to 6 Aug
฿3,284
฿3,662 total
5 Aug - 6 Aug
includes taxes & fees
Stay at this business-friendly hotel in Cape Coral. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
9.2/10 Wonderful! (1,559 reviews)
"I loved the room"
Reviewed on 3 Jul 2026
Baymont by Wyndham Fort Myers Central
4850 S Cleveland Ave Fort Myers FL
The price is ฿2,090 per night from 6 Jul to 7 Jul
฿2,090
฿2,331 total
6 Jul - 7 Jul
includes taxes & fees
Stay at this business-friendly hotel in Fort Myers. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean rooms ...
6.8/10 (1,127 reviews)
"I wasn’t informed prior to my reservation or after my reservation that the Internet wasn’t working towards the TV and I couldn’t get Wi-Fi on the television upon getting there. I was told this once I try to access the Wi-Fi on my video game system. I feel like that should’ve been disclosed prior ..."
Reviewed on 4 Jul 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in Matlacha Isles
Find the best Matlacha Isles areas for the activities you enjoy most.
Pelican
While visiting Pelican, you might make a stop by sights like Tarpon Point and Rotary Park Environmental Center.
Caloosahatchee
If you're spending some time in Caloosahatchee, Cape Coral Yacht Club Beach and Dolphin Marina are top sights worth seeing.
Yacht Club
While Yacht Club isn't home to many top sights, Cape Coral Yacht Club Beach and Cape Coral Farmers Market are some notable places to visit nearby.
Hancock
While visiting Hancock, you might make a stop by sights like Four Mile Cove Ecological Preserve and Pine Island Shopping Center.
Burnt Store
When in Burnt Store, you can plan a visit to Coral Oaks Golf Course and Lovegrove Gallery & Gardens, some noteworthy sights in the nearby area.
