The Best Hotels in Enterprise, Des Moines - 2026 Updated Prices

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Our top choices for Enterprise hotels

1. La Quinta Inn & Suites by Wyndham Ankeny IA - Des Moines IA

4.6 km from Enterprise

Karen

฿3,357 total

includes taxes & fees

27 Aug - 28 Aug

2. Courtyard Marriott Ankeny

4.4 km from Enterprise

Rachel

฿4,139 total

includes taxes & fees

27 Aug - 28 Aug

3. Comfort Inn & Suites Ankeny - Des Moines

4.2 km from Enterprise

Diane

฿3,502 total

includes taxes & fees

26 Aug - 27 Aug

4. Fairfield Inn & Suites Des Moines Altoona

8.9 km from Enterprise

Boyd

฿4,462 total

includes taxes & fees

23 Aug - 24 Aug

5. Hyatt Place Altoona/Des Moines

8.8 km from Enterprise

HEIDI

฿5,086 total

includes taxes & fees

23 Aug - 24 Aug

6. Best Western Premier Des Moines-Ankeny Hotel

4.6 km from Enterprise

Aubrei

฿3,858 total

includes taxes & fees

25 Aug - 26 Aug

7. Holiday Inn Express Des Moines Ankeny by IHG

5.6 km from Enterprise

฿3,481 total

includes taxes & fees

27 Aug - 28 Aug

8. Homewood Suites By Hilton Ankeny

4.5 km from Enterprise

Judy

฿5,211 total

includes taxes & fees

23 Aug - 24 Aug

Standard Room, 2 Queen Beds, Non Smoking | Desk, iron/ironing board, bed sheets

9. Sleep Inn & Suites Ankeny - Des Moines

4.7 km from Enterprise

Boyd

฿4,035 total

includes taxes & fees

25 Aug - 26 Aug

10. Hampton Inn & Suites Altoona-Des Moines

9.1 km from Enterprise

Jill

฿4,648 total

includes taxes & fees

26 Aug - 27 Aug

11. La Quinta by Wyndham Altoona Des Moines

8.7 km from Enterprise

Linette

฿3,357 total

includes taxes & fees

27 Aug - 28 Aug

12. Hampton Inn & Suites Ankeny

5.3 km from Enterprise

Cynthia

฿4,047 total

includes taxes & fees

27 Aug - 28 Aug

13. Country Inn & Suites by Radisson, Ankeny - Des Moines

4.7 km from Enterprise

Nancy

฿4,123 total

includes taxes & fees

25 Aug - 26 Aug

14. Home2 Suites By Hilton Altoona Des Moines

9.3 km from Enterprise

Susan

฿4,695 total

includes taxes & fees

26 Aug - 27 Aug

Premium bedding, pillow-top beds, desk, laptop workspace

15. My Place Hotel - Ankeny/ Des Moines, IA

4.6 km from Enterprise

Sherri

฿3,694 total

includes taxes & fees

24 Aug - 25 Aug

16. AmericInn by Wyndham Ankeny/Des Moines

4.6 km from Enterprise

Daniel

฿3,116 total

includes taxes & fees

27 Aug - 28 Aug

17. Holiday Inn Express Hotel & Suites Altoona-Des Moines by IHG

9.2 km from Enterprise

Amy

฿3,621 total

includes taxes & fees

23 Aug - 24 Aug

18. Tru By Hilton Ankeny

7.4 km from Enterprise

Christine

฿3,825 total

includes taxes & fees

27 Aug - 28 Aug

19. Staybridge Suites Des Moines North Ankeny by IHG

5.7 km from Enterprise

Scott

฿4,711 total

includes taxes & fees

27 Aug - 28 Aug

20. Comfort Inn Altoona-Des Moines

8.9 km from Enterprise

Rubyt

฿3,951 total

includes taxes & fees

26 Aug - 27 Aug

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Where to stay in Enterprise

Find the best Enterprise areas for the activities you enjoy most.

The entrance to the Greater Des Moines Botanical Garden with a large dome structure in the background.

Downtown Des Moines

The abundant dining options and live music are top of the list for many visitors to Downtown Des Moines. A stop by 801 Grand or Des Moines Civic Center might round out your trip.

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A city skyline at night with illuminated buildings and a prominent tower.

Court District

Travellers come to Court District for its abundant dining options, and you can see top attractions like Principal Park and Des Moines Civic Center while you're in town.

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The exterior and interior of Mars Cafe, featuring a brick facade, large windows, and a red interior with hanging lights and artwork.

Drake

While visiting Drake, you might make a stop by sights like Knapp Center and Des Moines Community Playhouse.

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Historic East Village

Find beautiful government buildings, cultural attractions and a garden oasis in this older section of the city extending along a pretty riverfront.

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A calm lake surrounded by trees and a stone bridge.

Greater South Side

While there might not be top attractions in Greater South Side, you can explore the larger area and discover places like Gray’s Lake Park and Lauridsen Amphitheater.

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Top Enterprise Hotel Reviews

Holiday Inn Downtown - Mercy Area by IHG

10/10 Excellent

"Close to event shuttle bus to casey center... Great time"

Hotel Fort Des Moines, Curio Collection by Hilton

8/10 Good

"The room was clean and the bed was so comfy!! Location was perfect, we could walk to many bars and restaurants. They had plenty of towels in the bathroom .The only two things I would complain about it that the elevator wasn’t working to the parking garage and they didn’t have any extra toilet paper paper in the bathroom."

Stoney Creek Hotel Des Moines - Johnston

8/10 Good

"This hotel was good for what we needed it for, which was a place to stay on a road trip. We got the executive cottage room, which was very spacious and having that massager was nice after being in a car for 9 hours. It was also kind of nice to be separate from the main hotel, as it was nice and quiet. There were decent options for breakfast. The coffee was made very well. The bed was neither too hard or too soft. We did have some issues with the TV, the picture would glitch on some of the channels and the remote glitched at times as well. We talked to the young man working that evening about it, and he gave us another remote, but said since he was the only worker he couldn't come over to the room to help us with it. He showed us how, but even following his instructions, the new remote didn't do what it was supposed to either. I also don't know if he wasn't aware of the equipment in the rooms, because he said to unplug the box to reset the TV, but there wasn't a box, just a cable screwed into the back of the TV. Again, it was a good place for what we needed, but I wouldn't go out of my way to stay multiple days."

Embassy Suites Hotel Des Moines Downtown

10/10 Excellent

"Wow! The room was amazing!! We loved the two rooms and kitchenette! Plus it’s super conveniently located close to downtown and Casey’s Center! Easy walk over to our Concert! All the staff from the restaurant, bar, registration, breakfast buffet servers, pool, everything was just top notch! We loved the hospitality and the valet service!! It was the best! Also we decided to book for Iowa State Fair after our stay!"

Frequently asked questions

What is Enterprise like?

Travellers to Bondurant's Enterprise neighbourhood will be sure to enjoy a stay here.

If I need to cancel my hotel reservation in Enterprise, will I receive a refund?

Yes, most room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before the scheduled arrival. If you have a non-refundable reservation, it might still be possible to cancel it and get a refund within a 24-hour period of your booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to view the top deals on offer in Enterprise.

What are the top things to see and do in Enterprise?

Otter Creek Golf Course is one place you might want to visit in the area around Enterprise. Make a stop at Adventureland and Outlets of Des Moines while you're sightseeing around the area.

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Our top choices for Enterprise hotels

1. La Quinta Inn & Suites by Wyndham Ankeny IA - Des Moines IA

2. Courtyard Marriott Ankeny

3. Comfort Inn & Suites Ankeny - Des Moines

4. Fairfield Inn & Suites Des Moines Altoona

5. Hyatt Place Altoona/Des Moines

6. Best Western Premier Des Moines-Ankeny Hotel

7. Holiday Inn Express Des Moines Ankeny by IHG

8. Homewood Suites By Hilton Ankeny

9. Sleep Inn & Suites Ankeny - Des Moines

10. Hampton Inn & Suites Altoona-Des Moines

11. La Quinta by Wyndham Altoona Des Moines

12. Hampton Inn & Suites Ankeny

13. Country Inn & Suites by Radisson, Ankeny - Des Moines

14. Home2 Suites By Hilton Altoona Des Moines

15. My Place Hotel - Ankeny/ Des Moines, IA

16. AmericInn by Wyndham Ankeny/Des Moines

17. Holiday Inn Express Hotel & Suites Altoona-Des Moines by IHG

18. Tru By Hilton Ankeny

19. Staybridge Suites Des Moines North Ankeny by IHG

20. Comfort Inn Altoona-Des Moines

Where to stay in Enterprise

Downtown Des Moines

Court District

Drake

Historic East Village

Greater South Side

Top Enterprise Hotel Reviews

Holiday Inn Downtown - Mercy Area by IHG

Frequently asked questions

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