Effingham Holiday Rentals, South Carolina: Private House Rentals

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Our top choices for Effingham hotels

A hotel room with a large bed, a desk with a chair, a television, and a walk-in closet.

A snack and beverage display area with shelves stocked with various brands and a refrigerator with beverages.

A breakfast setup with a flat-screen TV displaying a breakfast menu, a flat-screen TV, a coffee machine, and a tray of pancakes.

A coffee station with two coffee machines and a display of coffee pods and cups.

1. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

Florence

Leigh

฿3,988

฿4,467 total

includes taxes & fees

15 Nov - 16 Nov

A hotel lobby with a reception desk, seating area, and a television screen.

A hotel room with a sectional sofa, two ottomans, a bed with a green bedspread, and framed pictures on the wall.

A hotel room with a bed, a sofa, an ottoman, and a lamp.

A spacious dining area with multiple tables and chairs, large windows, and a flat-screen TV mounted on the wall.

2. Comfort Inn & Suites Florence Center Area

Florence

Mila

฿3,390

฿3,797 total

includes taxes & fees

8 Nov - 9 Nov

A rooftop terrace with outdoor seating, including sofas and chairs, and a round table.

A modern lounge area with brick walls, large windows, and contemporary furniture.

A modern bar area with a long counter, bar stools, and a variety of bottles and glasses.

A multi-story hotel with a modern facade, featuring a prominent 'Hyatt Place' sign on the right.

3. Hyatt Place Florence Downtown

Florence

Ivette

฿3,352

฿3,754 total

includes taxes & fees

3 Nov - 4 Nov

A hotel entrance with a stone facade, glass doors, and a number '501' above.

An indoor swimming pool with a tiled floor, a pool ladder, and lounge chairs.

A corner market with shelves stocked with snacks and beverages, and two large refrigerators.

A modern living room with a stone fireplace, a blue sofa, a brown leather chair, and a round coffee table.

4. Fairfield Inn & Suites by Marriott Florence I-20

Florence

฿3,960

฿4,435 total

includes taxes & fees

1 Nov - 2 Nov

A modern kitchen with dark wooden cabinets, a stainless steel refrigerator, a microwave, and a coffee maker. There is a dining area with two red chairs and a table.

An outdoor kitchen area with a grill, a pool, and a covered seating area.

A hotel room with a sofa, a dining table, a coffee maker, a TV, and artwork on the wall.

A conference room with round tables, chairs, and a carpeted floor.

5. Staybridge Suites Florence - Civic Center by IHG

Florence

Tishia

฿4,525

฿5,067 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a bed, a desk, a green sofa, and a painting on the wall.

A hotel room with a desk, a green armchair, a small purple ottoman, a bed with a white headboard, and a large window.

A spacious lobby with a reception desk, seating area with patterned chairs, and a coffee station.

6. Home2 Suites by Hilton Florence, SC

Florence

saleh

฿3,704

฿4,349 total

includes taxes & fees

4 Nov - 5 Nov

A modern living room with a gray sofa, colorful vases, and a geometric-patterned rug.

A modern kitchen with dark wood cabinets, a central island with a glass enclosure, and a white countertop.

A hotel with a sign reading "Homewood Suites Hilton" and a landscaped entrance area with a circular brick pathway and benches.

A modern lounge area with a fireplace, comfortable seating, and a decorative wall.

7. Homewood Suites by Hilton Florence

Florence

Aekyung

฿3,532

฿4,288 total

includes taxes & fees

15 Nov - 16 Nov

A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.

A Hampton Inn & Suites with a large sign, brick facade, and a parking lot.

A hotel lobby with a reception desk, seating area, and a welcome mat.

A hotel room with two beds, a desk, a TV, and a window with patterned curtains.

8. Hampton Inn & Suites Florence Center

Florence

Ryan

฿3,817

฿4,275 total

includes taxes & fees

1 Nov - 2 Nov

A spacious lobby with a reception desk, seating area, and large windows.

A spacious lobby with a large fireplace, comfortable seating, and potted plants.

A reception area with a counter, a sign for 'The Pavilion Pantry', and a green wall.

A Hilton Garden Inn with a large, multi-story building, a covered entrance, and a parking lot.

9. Hilton Garden Inn Florence

Florence

Derrick

฿3,960

฿4,435 total

includes taxes & fees

15 Nov - 16 Nov

A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.

A self-service beverage station with refrigerated and non-refrigerated drink options, snack shelves, and a sign indicating the location.

A modern hotel room with a kitchenette, a grey sofa, a dining area, and a sign that reads "A Great Day Starts With Breakfast."

A modern lounge area with a sofa, armchairs, and small tables.

10. TownePlace Suites by Marriott Florence

Florence

Crystal

฿3,675

฿4,116 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with two beds, a wooden headboard, a window with curtains, and a wall-mounted air conditioner.

An indoor swimming pool with clear blue water, surrounded by green chairs and a tiled floor.

A modern kitchen with a built-in coffee station, a refrigerator, and a seating area with a patterned rug.

A spacious lobby with a reception desk, a large window display, and a 'market' sign on the wall.

11. SpringHill Suites by Marriott Florence

Florence

John

฿3,398

฿4,005 total

includes taxes & fees

30 Oct - 31 Oct

A spacious lobby with a high ceiling, a central seating area with armchairs and a coffee table, a flat-screen TV, and a dining area with tables and chairs.

A spacious lobby with a large seating area, a flat-screen TV, and a fireplace.

A modern hotel lobby with a central seating area, a large abstract painting, and a patterned carpet.

A modern hotel lobby with a fireplace, seating area, and a reception desk.

12. Residence Inn Marriott Florence

Florence

Teri

฿3,593

฿4,024 total

includes taxes & fees

16 Nov - 17 Nov

A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.

A modern living room with a grey sofa, a flat-screen TV, geometric wall art, and a bookshelf with decorative items.

A modern hotel with a 'Park Inn by Radisson' sign, featuring a covered entrance, multiple windows, and a parking lot.

A modern kitchen with a patterned backsplash, wooden cabinets, and stainless steel appliances.

13. Park Inn by Radisson Florence, SC

Florence

Juan

฿2,993

฿3,352 total

includes taxes & fees

1 Nov - 2 Nov

A restaurant with brick walls, framed awards, and a bar area.

An outdoor patio area with a brick wall, a covered seating area with string lights, and potted plants.

A spacious living room with a wooden floor, a ceiling fan, and a dining area with a wooden table and chairs.

A spacious kitchen with a dining area, a living room with a fireplace, and a cozy seating arrangement.

14. Hotel Florence, Tapestry Collection by Hilton

Florence

Ankh

฿4,645

฿5,202 total

includes taxes & fees

15 Nov - 16 Nov

A modern hotel with a covered entrance, large windows, and a sign indicating it is a hotel.

A modern lounge area with a pool table, sofas, and yellow chairs.

A bar area with a neon sign, shelves of bottles, and a view of trees through large windows.

15. Aloft by Marriott Florence

Florence

Shilow

฿3,727

฿4,374 total

includes taxes & fees

22 Oct - 23 Oct

An outdoor seating area with a fire pit, cushioned seating, and a pergola with string lights.

A modern hotel with a prominent 'TRU by Hilton' sign, a well-lit entrance, and a landscaped front yard.

A modern lounge area with seating, tables, and a pool table.

A modern hotel restaurant with a breakfast bar, seating area, and a view of the city.

16. Tru by Hilton Florence I-95

Florence

Tiffany

฿3,675

฿4,315 total

includes taxes & fees

22 Oct - 23 Oct

A spacious lobby with a checkered floor, a reception desk, and a chandelier.

A hotel room with two beds, a desk with a computer, a chair, and a bathroom with a mirror.

A vending area with snack and drink options, including Pepsi refrigerators and a 'MARKET' display with various products.

A spacious dining area with multiple tables and chairs, large windows offering a view of the parking lot, and a television mounted on the wall.

17. Howard Johnson by Wyndham Florence

Florence

Alanda

฿2,165

฿2,425 total

includes taxes & fees

29 Oct - 30 Oct

A spacious hotel lobby with multiple seating areas, including tables and chairs, a reception desk, and a staircase leading to an upper level.

An indoor swimming pool with clear water, surrounded by a checkered wall pattern, and equipped with multiple seating areas and a lifeguard station.

A corridor with shelves stocked with snacks and a frozen food display.

A lobby with leather sofas, a coffee table, potted plants, and a reception desk.

18. Hampton Inn & Suites Florence-North-I-95

Florence

Ashokraju

฿4,102

฿4,595 total

includes taxes & fees

22 Oct - 23 Oct

A hotel room with a desk, chair, bed, and a yellow sofa.

A hotel with a green roof, a sign reading 'Quality Inn & Suites by Choice Hotels,' and a landscaped front yard with small trees and shrubs.

A reception desk with a stone wall backdrop, a sign reading 'Quality Choice Hotels,' and a reception area with a wooden reception desk and two chairs.

A swimming pool with lounge chairs and a building with balconies.

19. Quality Inn & Suites Florence Civic Center

Florence

Sharhonda

฿2,986

฿3,345 total

includes taxes & fees

27 Oct - 28 Oct

A modern lobby with seating areas, a reception desk, and a large wall with a decorative panel.

A Comfort Suites hotel with a modern design, featuring a prominent entrance with columns, a covered walkway, and a clear blue sky.

An outdoor patio area with tables and chairs, a barbecue grill, and a large window overlooking a fenced area.

A hotel room with a bed, a blue sofa, a brown ottoman, a black office chair, a desk, a lamp, and three framed pictures on the wall.

20. Comfort Suites Florence I-95

Florence

Jennifer

฿3,057

฿3,757 total

includes taxes & fees

15 Nov - 16 Nov

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Top Effingham Hotel Reviews

Best Western Executive Inn

10/10 Excellent

"Overnight stay while solo traveling. Clean, safe and friendly. Breakfast was the usual. Not bad but not great. For the price this was a great choice."

Howard Johnson by Wyndham Florence

8/10 Good

"Staff was helpful, Rooms were definitely an upgrade from the Days Inns I had been staying in!! Continental breakfast was okay, would have liked to have bananas and some yogurt!!"

Comfort Inn & Suites Florence Center Area

10/10 Excellent

"Room was very clean and modern. Price was good. Good breakfast."

Super 8 by Wyndham Florence

8/10 Good

"."

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

8/10 Good

"Good"

Comfort Suites Florence I-95

10/10 Excellent

"Everything was excellent- the staff, the rooms, the parking, you name it. Very satisfied"

More cheap stays in Effingham

Howard Johnson by Wyndham Florence

2038 W Lucas Street Florence SC

฿2,165

฿2,425 total

29 Oct - 30 Oct

includes taxes & fees

Days Inn by Wyndham Florence Near Civic Center

140 Dunbarton Dr Florence SC

฿2,313

฿2,590 total

27 Oct - 28 Oct

includes taxes & fees

Quality Inn & Suites Florence Civic Center

150 Dunbarton Dr Florence SC

฿2,986

฿3,345 total

27 Oct - 28 Oct

includes taxes & fees

Park Inn by Radisson Florence, SC

1729 Mandeville Road Florence SC

฿2,993

฿3,352 total

1 Nov - 2 Nov

includes taxes & fees

Comfort Inn & Suites Florence Center Area

527 Woody Jones Blvd Florence SC

฿3,390

฿3,797 total

8 Nov - 9 Nov

includes taxes & fees

9/10 Wonderful! (1,369 reviews)

The Inn at the Crossroads

128 West Main Street Lake City SC

฿3,736

฿4,184 total

15 Nov - 16 Nov

includes taxes & fees

Frequently asked questions

Where is the best place to stay in Effingham?

Park Inn by Radisson Florence, SC, located 12.2 mi (19.6 km) from the heart of Effingham, is a top choice for your stay, based on our traveller data. Other good options for your trip to the area are Howard Johnson by Wyndham Florence and Quality Inn & Suites Florence Civic Center. See all available top hotels, or vacation rentals in Effingham.

If I need to cancel my hotel reservation in Effingham, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable if cancelled prior to the accommodation's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within 24 hours of your booking. Filter your search by fully refundable to find flexible hotel deals in Effingham.

What's it like to stay in Effingham?

Travellers to Effingham will find plenty to explore and enjoy. There are 160 hotels and other accommodation options in the surrounding area. Find out more about Effingham.

What should I see while I'm in Effingham?

A favourite place to visit is Lynches River State Park. You'll also find Florence National Cemetery and Florence County Museum in the area. Take a look at what more there is to see and do in Expedia's Effingham guide.

What's the seasonal weather in Effingham?

The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 10°C. Average annual precipitation for Effingham is 1366 mm.

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Book Hotels in Effingham on Expedia.com

Find hotels in Effingham, SC from ฿2,425

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Effingham

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Effingham hotels

1. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

2. Comfort Inn & Suites Florence Center Area

3. Hyatt Place Florence Downtown

4. Fairfield Inn & Suites by Marriott Florence I-20

5. Staybridge Suites Florence - Civic Center by IHG

6. Home2 Suites by Hilton Florence, SC

7. Homewood Suites by Hilton Florence

8. Hampton Inn & Suites Florence Center

9. Hilton Garden Inn Florence

10. TownePlace Suites by Marriott Florence

11. SpringHill Suites by Marriott Florence

12. Residence Inn Marriott Florence

13. Park Inn by Radisson Florence, SC

14. Hotel Florence, Tapestry Collection by Hilton

15. Aloft by Marriott Florence

16. Tru by Hilton Florence I-95

17. Howard Johnson by Wyndham Florence

18. Hampton Inn & Suites Florence-North-I-95

19. Quality Inn & Suites Florence Civic Center

20. Comfort Suites Florence I-95

Top Effingham Hotel Reviews

Best Western Executive Inn

Howard Johnson by Wyndham Florence

Comfort Inn & Suites Florence Center Area

Super 8 by Wyndham Florence

Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

Comfort Suites Florence I-95

More cheap stays in Effingham

Howard Johnson by Wyndham Florence

Days Inn by Wyndham Florence Near Civic Center

Quality Inn & Suites Florence Civic Center

Park Inn by Radisson Florence, SC

Comfort Inn & Suites Florence Center Area

The Inn at the Crossroads

Frequently asked questions

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