Search Hotels in East End, Sanibel

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Our top choices for East End hotels

Tarpon Tale Inn

Tarpon Tale Inn
3.0 star property
East End
9.6 out of 10, Exceptional, (392)
"Great staff, close to the beach. Provided beach chairs, umbrella, & beach cart for stay. Highly recommend"
United States
Thomas
The price is ฿7,035
฿7,844 total
includes taxes & fees
4 Jan - 5 Jan 2026
Tarpon Tale Inn

Sanibel Inn

Sanibel Inn
3.0 star property
East End
9.0 out of 10, Wonderful, (1000)
"Very nice hotel/resort. Clean, quiet, nice pool, attentive staff. Love the screened in balcony. "
Canada
Jonathan
The price is ฿11,076
฿14,170 total
includes taxes & fees
5 Jan - 6 Jan 2026
Sanibel Inn

Matlacha on Shoreview

Matlacha on Shoreview
2.0 star property
21.4 km from East End
9.6 out of 10, Exceptional, (213)
"Place was great. Nice and neat perfect for what i needed."
United States
Michael
The price is ฿1,727
฿4,027 total
includes taxes & fees
23 Dec - 24 Dec
Matlacha on Shoreview

The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village
4.0 star property
10.7 km from East End
9.0 out of 10, Wonderful, (1004)
"Excellent stay over Thanksgiving holiday!"
United States
Nicole
The price is ฿5,172
฿7,023 total
includes taxes & fees
23 Dec - 24 Dec
The Westin Cape Coral Resort At Marina Village

Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers

Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers
3.0 star property
26 km from East End
9.4 out of 10, Exceptional, (746)
"Always great to stay here. "
United States
David
The price is ฿4,114
฿4,588 total
includes taxes & fees
23 Dec - 24 Dec
Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers

OYO Waterfront Hotel - Cape Coral/Fort Myers, FL

OYO Waterfront Hotel - Cape Coral/Fort Myers, FL
2.5 star property
17.6 km from East End
5.8 out of 10, (1004)
"Beautiful place "
United States
Blaine
The price is ฿2,270
฿2,751 total
includes taxes & fees
28 Dec - 29 Dec
OYO Waterfront Hotel - Cape Coral/Fort Myers, FL

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
2.5 star property
14.7 km from East End
8.6 out of 10, Excellent, (1002)
"The rooms were clean, staff were very friendly and accommodating."
United States
Sandra
The price is ฿3,837
฿4,279 total
includes taxes & fees
1 Jan - 2 Jan 2026
Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Dolphin Key Resort

Dolphin Key Resort
3.0 star property
15.1 km from East End
8.8 out of 10, Excellent, (1210)
"Nice room, helpful staff, nice heated pool, bar/restaurant on site has good prices and live entertainment most nights. Overall, a fun place to stay."
United States
Jacob
The price is ฿3,141
฿3,502 total
includes taxes & fees
23 Dec - 24 Dec
Dolphin Key Resort

Vanderbilt Beach Resort

Vanderbilt Beach Resort
2.5 star property
29.8 km from East End
9.4 out of 10, Exceptional, (424)
"Great stay. "
Canada
Joseph
The price is ฿11,071
฿13,264 total
includes taxes & fees
24 Dec - 25 Dec
Vanderbilt Beach Resort

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 star property
15.3 km from East End
9.4 out of 10, Exceptional, (1070)
"Is great place to stay."
United States
Anastassia
The price is ฿4,052
฿4,518 total
includes taxes & fees
23 Dec - 24 Dec
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

The Perry Hotel Naples

The Perry Hotel Naples
4.5 star property
29.3 km from East End
9.6 out of 10, Exceptional, (533)
"Great hotel! Beautiful area and views, stunning pool and lounge area, wonderful staff and very warm and welcoming!"
United States
MARYAM
The price is ฿6,508
฿8,792 total
includes taxes & fees
8 Jan - 9 Jan 2026
The Perry Hotel Naples

SpringHill Suites by Marriott Fort Myers Estero

SpringHill Suites by Marriott Fort Myers Estero
2.5 star property
24.7 km from East End
9.2 out of 10, Wonderful, (824)
"Friendly staff, spectacular rooms & amenities. Breakfast menu was my favorite part! "
United States
Simone
The price is ฿4,397
฿5,060 total
includes taxes & fees
4 Jan - 5 Jan 2026
SpringHill Suites by Marriott Fort Myers Estero

TownePlace Suites by Marriott Fort Myers Estero

TownePlace Suites by Marriott Fort Myers Estero
3.5 star property
23 km from East End
9.4 out of 10, Exceptional, (467)
"Clean room and very nice staff"
United States
Nancy
The price is ฿4,994
฿5,568 total
includes taxes & fees
1 Jan - 2 Jan 2026
TownePlace Suites by Marriott Fort Myers Estero

DoubleTree Suites by Hilton Naples

DoubleTree Suites by Hilton Naples
4.0 star property
29.3 km from East End
9.2 out of 10, Wonderful, (1001)
"Clean, quiet and nice rooms!"
United States
Rheah
The price is ฿7,086
฿7,865 total
includes taxes & fees
24 Dec - 25 Dec
DoubleTree Suites by Hilton Naples

Embassy Suites by Hilton Fort Myers Estero

Embassy Suites by Hilton Fort Myers Estero
3.5 star property
24.8 km from East End
9.2 out of 10, Wonderful, (1064)
"Loved the breakfast and nightly drinks provided by the hotel. Rooms were spacious and clean and provided a great landing spot during our trip. "
United States
Kerry
The price is ฿4,598
฿5,126 total
includes taxes & fees
25 Dec - 26 Dec
Embassy Suites by Hilton Fort Myers Estero

Hyatt Vacation Club at Coconut Cove, Bonita Springs

Hyatt Vacation Club at Coconut Cove, Bonita Springs
4.0 star property
19.7 km from East End
9.2 out of 10, Wonderful, (738)
"Room great clean, staff great.loved pool"
United States
Dennis
The price is ฿6,274
฿8,221 total
includes taxes & fees
6 Jan - 7 Jan 2026
Hyatt Vacation Club at Coconut Cove, Bonita Springs

Hampton Inn & Suites Fort Myers-Estero/FGCU

Hampton Inn & Suites Fort Myers-Estero/FGCU
2.5 star property
24.9 km from East End
9.2 out of 10, Wonderful, (1000)
"Exellent service"
United States
Issanel
The price is ฿3,884
฿4,331 total
includes taxes & fees
25 Dec - 26 Dec
Hampton Inn & Suites Fort Myers-Estero/FGCU

Drury Inn & Suites Fort Myers Airport FGCU

Drury Inn & Suites Fort Myers Airport FGCU
3.0 star property
24.4 km from East End
9.8 out of 10, Exceptional, (1003)
"The staff was beyond helpful and friendly. "
United States
Frederick
The price is ฿4,397
฿4,902 total
includes taxes & fees
24 Dec - 25 Dec
Drury Inn & Suites Fort Myers Airport FGCU

Resort Harbour Properties

Resort Harbour Properties
3.5 star property
4.8 km from East End
9.6 out of 10, Exceptional, (364)
"10/10 would stay there again"
United States
Kristie
Resort Harbour Properties

Hyatt Place Fort Myers Estero

Hyatt Place Fort Myers Estero
3.5 star property
22.6 km from East End
8.8 out of 10, Excellent, (1002)
"Great staff!"
United States
Marlene
The price is ฿5,120
฿5,708 total
includes taxes & fees
23 Dec - 24 Dec
Hyatt Place Fort Myers Estero
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in East End

Find the best East End areas for the activities you enjoy most.

West End

If you're spending some time in West End, J. N. Ding Darling National Wildlife Refuge and Bowman's Beach are top sights worth seeing.

Mid Island

If you're spending some time in Mid Island, Periwinkle Way and Sanibel Island Southern Beach are top sights worth seeing.

Beachview Country Club Estates

While visiting Beachview Country Club Estates, you might make a stop by sights like Periwinkle Way and Sanibel Island Golf Club.

Sanctuary

While there might not be top attractions in Sanctuary, you can explore the larger area and discover places like Blind Pass Beach and Turner Beach.

Shell Harbor

While Shell Harbor isn't home to many top sights, Sanibel Sea School and Dunes Golf and Tennis Club are some notable places to visit nearby.

Top East End Hotel Reviews

Frequently asked questions

What's it like in East End?
Travellers will be sure to find plenty to entertain them in Sanibel's East End neighbourhood. Make sure that you visit Sanibel Island Northern Beach and Sanibel Island Lighthouse as part of your East End travel plans.
Where is the best place to stay in East End?
Based on Expedia customer reviews, Tarpon Tale Inn is the highest ranked property in East End. This hotel is a short 6-minute walk from Sanibel Island Southern Beach, and it offers free parking and private patios. Another top choice in the area is Sanibel Inn.
How many hotels will I find in the East End area?
Expedia has 560 hotels and other accommodation options in East End to choose from, making this an ideal home base for exploring the greater Sanibel area.
If I need to cancel my hotel reservation in East End, will I receive a refund?
Yes, the majority of hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might be able to still cancel and receive a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then filter by "fully refundable" to view top deals in East End.
What are the top things to see and do in East End?
Dip your toes in the water at Sanibel Island Northern Beach, Sanibel Island Southern Beach and Causeway Islands Beaches while you're in East End. Sanibel Island Lighthouse and Periwinkle Way are also a couple of places to visit in the neighbourhood. Sanibel Sea School, Sanibel Moorings Botanical Gardens and Bailey's Beach are just a few of the places to visit in and around East End. Dunes Golf and Tennis Club and Causeway Islands Park B are also worth a visit when you're out sightseeing in Sanibel.