Search Hotels Near Don Harrington Discovery Center, Amarillo

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
21 Dec - 22 Dec
Tomorrow
22 Dec - 23 Dec
Next weekend
26 Dec - 28 Dec
In two weeks
2 Jan - 4 Jan

Filter by

Guest rating
Guest rating
Star rating

Our top choices for Don Harrington Discovery Center hotels

Lobby
Best Western Plus Medical Center

Best Western Plus Medical Center

Best Western Plus Medical Center
2.5 star property
1.1 km from Don Harrington Discovery Center
9.4 out of 10, Exceptional, (2081)
"Staff was courteous and efficient with check-in. Room clean, well appointed and quiet. "
United States
James
The price is ฿3,081
฿3,544 total
includes taxes & fees
25 Dec - 26 Dec
Best Western Plus Medical Center
37-inch LCD TV with cable channels, TV, iPod dock
Holiday Inn Express & Suites Amarillo West by IHG

Holiday Inn Express & Suites Amarillo West by IHG

Holiday Inn Express & Suites Amarillo West by IHG
2.5 star property
2.1 km from Don Harrington Discovery Center
9.4 out of 10, Exceptional, (2013)
"Great hotel "
United States
Sara
The price is ฿3,141
฿3,612 total
includes taxes & fees
19 Jan - 20 Jan 2026
Holiday Inn Express & Suites Amarillo West by IHG
Lobby
Drury Inn & Suites Amarillo

Drury Inn & Suites Amarillo

Drury Inn & Suites Amarillo
3.0 star property
2.6 km from Don Harrington Discovery Center
9.4 out of 10, Exceptional, (2206)
"We had a great stay!! Friendly staff, clean rooms and enjoyed the amenities."
United States
Araceli
The price is ฿2,669
฿3,070 total
includes taxes & fees
4 Jan - 5 Jan 2026
Drury Inn & Suites Amarillo
Property amenity
TownePlace Suites by Marriott Amarillo West/Medical Center

TownePlace Suites by Marriott Amarillo West/Medical Center

TownePlace Suites by Marriott Amarillo West/Medical Center
3.0 star property
1.7 km from Don Harrington Discovery Center
9.4 out of 10, Exceptional, (478)
"Room was very clean and staff were very professional and friendly."
United States
Rosabel
The price is ฿3,549
฿4,081 total
includes taxes & fees
25 Dec - 26 Dec
TownePlace Suites by Marriott Amarillo West/Medical Center
Terrace/patio
Hampton Inn & Suites Amarillo West

Hampton Inn & Suites Amarillo West

Hampton Inn & Suites Amarillo West
2.5 star property
2.4 km from Don Harrington Discovery Center
9.4 out of 10, Exceptional, (401)
"Clean room, friendly staff, comfortable bed and room decor. "
United States
Noemi
The price is ฿3,065
฿3,525 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn & Suites Amarillo West
Premium bedding, pillow-top beds, desk, laptop workspace
My Place Hotel - Amarillo West/ Medical Center, TX

My Place Hotel - Amarillo West/ Medical Center, TX

My Place Hotel - Amarillo West/ Medical Center, TX
2.5 star property
2.3 km from Don Harrington Discovery Center
9.2 out of 10, Wonderful, (1311)
"Second time staying and enjoyed it again. Very clean."
United States
Stephen
The price is ฿2,318
฿2,666 total
includes taxes & fees
29 Dec - 30 Dec
My Place Hotel - Amarillo West/ Medical Center, TX
Interior
Tru By Hilton Amarillo West

Tru By Hilton Amarillo West

Tru By Hilton Amarillo West
2.5 star property
2.7 km from Don Harrington Discovery Center
9.2 out of 10, Wonderful, (1105)
"Clean nice place and staff"
United States
Ron
The price is ฿2,421
฿2,803 total
includes taxes & fees
31 Dec - 1 Jan 2026
Tru By Hilton Amarillo West
Property amenity
Springhill Suites by Marriott Amarillo

Springhill Suites by Marriott Amarillo

Springhill Suites by Marriott Amarillo
3.0 star property
2.3 km from Don Harrington Discovery Center
9.2 out of 10, Wonderful, (1002)
"Great place"
United States
Mary
The price is ฿3,235
฿3,720 total
includes taxes & fees
29 Dec - 30 Dec
Springhill Suites by Marriott Amarillo
Front of property – evening/night
Hyatt Place Amarillo-West

Hyatt Place Amarillo-West

Hyatt Place Amarillo-West
3.0 star property
2.8 km from Don Harrington Discovery Center
9.2 out of 10, Wonderful, (1367)
"We like to stay there when we head to Prescott, Arizona. It is convenient and has many restaurants around to chose from! The staff is super nice. "
United States
Charles
The price is ฿2,638
฿3,087 total
includes taxes & fees
4 Jan - 5 Jan 2026
Hyatt Place Amarillo-West
Dining
Yellow City Studios

Yellow City Studios

Yellow City Studios
2.0 star property
1.3 km from Don Harrington Discovery Center
9.0 out of 10, Wonderful, (11)
"Highly recommend, clean, quiet and peaceful. The staff very nice and professional. "
United States
Jared
The price is ฿2,481
฿2,853 total
includes taxes & fees
26 Dec - 27 Dec
Yellow City Studios
Terrace/patio
Home2 Suites by Hilton Amarillo

Home2 Suites by Hilton Amarillo

Home2 Suites by Hilton Amarillo
3.0 star property
1.9 km from Don Harrington Discovery Center
9.0 out of 10, Wonderful, (1004)
"Excellent customer service. 2nd time staying here. "
United States
Samantha
The price is ฿2,636
฿3,031 total
includes taxes & fees
11 Jan - 12 Jan 2026
Home2 Suites by Hilton Amarillo
Indoor pool
Country Inn & Suites by Radisson, Amarillo I-40 West, TX

Country Inn & Suites by Radisson, Amarillo I-40 West, TX

Country Inn & Suites by Radisson, Amarillo I-40 West, TX
3.0 star property
2.7 km from Don Harrington Discovery Center
9.0 out of 10, Wonderful, (2450)
"Best beds from this trip and warm atmosphere very welcoming "
United States
Donna
The price is ฿2,241
฿2,577 total
includes taxes & fees
4 Jan - 5 Jan 2026
Country Inn & Suites by Radisson, Amarillo I-40 West, TX
Lobby
Everhome Suites Amarillo West - Medical Center

Everhome Suites Amarillo West - Medical Center

Everhome Suites Amarillo West - Medical Center
2.0 star property
1.9 km from Don Harrington Discovery Center
8.8 out of 10, Excellent, (106)
"Easy stay and pet friendly. "
United States
Brittany
The price is ฿2,643
฿3,039 total
includes taxes & fees
4 Jan - 5 Jan 2026
Everhome Suites Amarillo West - Medical Center
Free daily continental breakfast
Microtel Inn & Suites By Wyndham Amarillo West

Microtel Inn & Suites By Wyndham Amarillo West

Microtel Inn & Suites By Wyndham Amarillo West
2.5 star property
2.8 km from Don Harrington Discovery Center
8.8 out of 10, Excellent, (577)
"Enjoyed our stay "
United States
Frank
The price is ฿2,346
฿2,698 total
includes taxes & fees
22 Dec - 23 Dec
Microtel Inn & Suites By Wyndham Amarillo West
Restaurant
Homewood Suites by Hilton Amarillo

Homewood Suites by Hilton Amarillo

Homewood Suites by Hilton Amarillo
3.0 star property
2.9 km from Don Harrington Discovery Center
8.8 out of 10, Excellent, (1004)
"Very clean, great staff, comfortable beds"
United States
Heather
The price is ฿2,189
฿2,518 total
includes taxes & fees
4 Jan - 5 Jan 2026
Homewood Suites by Hilton Amarillo
Lobby lounge
Fairfield Inn & Suites Amarillo West/Medical Center

Fairfield Inn & Suites Amarillo West/Medical Center

Fairfield Inn & Suites Amarillo West/Medical Center
2.5 star property
1.4 km from Don Harrington Discovery Center
8.4 out of 10, Very good, (755)
"Very nice and helpful staff. "
United States
Alicia
The price is ฿3,043
฿3,570 total
includes taxes & fees
25 Dec - 26 Dec
Fairfield Inn & Suites Amarillo West/Medical Center
Exterior
Comfort Inn & Suites Amarillo West near Medical Center

Comfort Inn & Suites Amarillo West near Medical Center

Comfort Inn & Suites Amarillo West near Medical Center
2.5 star property
2.8 km from Don Harrington Discovery Center
8.6 out of 10, Excellent, (1201)
"breakfast was really nice comfortable room and quiet."
United States
Layne
The price is ฿1,923
฿2,212 total
includes taxes & fees
30 Dec - 31 Dec
Comfort Inn & Suites Amarillo West near Medical Center
Exterior
Sleep Inn & Suites West Medical Center

Sleep Inn & Suites West Medical Center

Sleep Inn & Suites West Medical Center
2.5 star property
1.6 km from Don Harrington Discovery Center
8.2 out of 10, Very good, (1007)
"Great check in, room, bed... all really good! Thanks for a good night sleep. "
United States
Kristy
The price is ฿1,976
฿2,272 total
includes taxes & fees
12 Jan - 13 Jan 2026
Sleep Inn & Suites West Medical Center
Free daily continental breakfast
Spark by Hilton Amarillo Medical Center

Spark by Hilton Amarillo Medical Center

Spark by Hilton Amarillo Medical Center
2.5 star property
1.6 km from Don Harrington Discovery Center
8.0 out of 10, Very good, (744)
"Staff was nice and loved the area "
United States
Briones
The price is ฿2,035
฿2,340 total
includes taxes & fees
28 Dec - 29 Dec
Spark by Hilton Amarillo Medical Center
Lobby sitting area
Holiday Inn Amarillo West Medical Center by IHG

Holiday Inn Amarillo West Medical Center by IHG

Holiday Inn Amarillo West Medical Center by IHG
3.0 star property
2.1 km from Don Harrington Discovery Center
8.0 out of 10, Very good, (1000)
"Awesome stay"
United States
Robert
The price is ฿2,450
฿2,817 total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Amarillo West Medical Center by IHG
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Don Harrington Discovery Center Hotel Reviews

Best Western Plus Medical Center

Best Western Plus Medical Center

10/10 Excellent
"The room is spacious and clean. The front desk staff is very responsive. The breakfast is fantastic!"
Jie 1-night trip
Posted 7 days ago
Best Western Plus Medical Center

Hotels near other Don Harrington Discovery Center attractions

Amarillo Botanical Gardens

4.2/5 (122 reviews)
Explore the great outdoors at Amarillo Botanical Gardens, a lovely green space in Amarillo. Attend a sporting event while in this family-friendly area or simply enjoy the top-notch restaurants.
See properties

Helium Monument

Learn about the local history of Amarillo when you take a trip to Helium Monument. Attend a sporting event while in this family-friendly area or simply enjoy the top-notch restaurants.
See properties

Frequently asked questions

What's the area like around Don Harrington Discovery Center?
Don Harrington Discovery Center is located in a family-friendly area of Amarillo known for its array of dining options and sporting events. If you're looking for a convenient place to stay, take a look at the 25 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay near Don Harrington Discovery Center?
Best Western Plus Medical Center is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. It's located just a short 0.7 mi (1.1 km) from Don Harrington Discovery Center. Other good options within a short distance include Red Roof Inn Amarillo West and Spark by Hilton Amarillo Medical Center.
How many hotels will I find near Don Harrington Discovery Center?
Expedia has 25 hotels and other accommodation options within a mile from Don Harrington Discovery Center.
If I need to cancel the hotel reservation for my stay near Don Harrington Discovery Center, will I receive a refund?
Yes! You'll find that most hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of check in. If you have a reservation that's non-refundable, it might still be possible to cancel it and be given a refund within 24 hours of booking. Enter your dates, click on "Search", then filter by "fully refundable" to view the best deals available near Don Harrington Discovery Center.
What can I see and do near Don Harrington Discovery Center?
You'll want to browse the exhibits at Amarillo Art Center and Amarillo Museum of Art. Sights like Harrington House and Historic 6th Street Sign highlight some of the local culture. You can enjoy live performances at Amarillo Little Theatre and Globe-News Center.