Search Business Hotels in South Carolina

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Check availability on South Carolina Business Hotels

Tonight
20 Dec - 21 Dec
Tomorrow
21 Dec - 22 Dec
Next weekend
26 Dec - 28 Dec
In two weeks
2 Jan - 4 Jan

Our top choices for South Carolina business-friendly hotels

Coffee service
Comfort Inn Greenville - Haywood Mall

Comfort Inn Greenville - Haywood Mall

Comfort Inn Greenville - Haywood Mall
2.5 star property
Greenville
8.0 out of 10, Very good, (1001)
"Clean room"
United States
Loogeok Lydia
The price is ฿2,405
฿2,739 total
includes taxes & fees
21 Dec - 22 Dec
Comfort Inn Greenville - Haywood Mall
Exterior
Hyatt Place Charleston Airport/Convention Center

Hyatt Place Charleston Airport/Convention Center

Hyatt Place Charleston Airport/Convention Center
3.0 star property
North Charleston
9.4 out of 10, Exceptional, (1151)
"Clean room, nice staff, amenities were all great."
United States
Keisha
The price is ฿2,858
฿3,415 total
includes taxes & fees
30 Dec - 31 Dec
Hyatt Place Charleston Airport/Convention Center
Restaurant
Sheraton Columbia Downtown Hotel

Sheraton Columbia Downtown Hotel

Sheraton Columbia Downtown Hotel
3.5 star property
Downtown Columbia
8.4 out of 10, Very good, (1003)
"Clean rooms and hospitable staff!"
United States
James
The price is ฿3,175
฿3,556 total
includes taxes & fees
31 Dec - 1 Jan 2026
Sheraton Columbia Downtown Hotel
Front of property
Town & Country Inn and Suites

Town & Country Inn and Suites

Town & Country Inn and Suites
3.0 star property
West Ashley
9.2 out of 10, Wonderful, (1495)
"Always a great stay!!"
United States
Nicole
Town & Country Inn and Suites
Lobby
Sleep Inn at Greenville Convention Cente

Sleep Inn at Greenville Convention Cente

Sleep Inn at Greenville Convention Cente
2.5 star property
Greenville
8.0 out of 10, Very good, (1001)
"Convenient to convention center, staff very good, rooms outdated"
United States
candy
The price is ฿2,483
฿2,811 total
includes taxes & fees
21 Dec - 22 Dec
Sleep Inn at Greenville Convention Cente
Exterior
La Quinta Inn & Suites by Wyndham Greenville Haywood

La Quinta Inn & Suites by Wyndham Greenville Haywood

La Quinta Inn & Suites by Wyndham Greenville Haywood
3.0 star property
Greenville
7.4 out of 10, Good, (1122)
"Kind staff, clean room, tasty continental breakfast!"
United States
Karen
The price is ฿2,150
฿2,365 total
includes taxes & fees
21 Dec - 22 Dec
La Quinta Inn & Suites by Wyndham Greenville Haywood
Terrace/patio
Home2 Suites by Hilton Greenville Downtown

Home2 Suites by Hilton Greenville Downtown

Home2 Suites by Hilton Greenville Downtown
3.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (1001)
"Super clean! Friendly staff and breakfast was great!"
United States
April
The price is ฿3,454
฿3,799 total
includes taxes & fees
28 Dec - 29 Dec
Home2 Suites by Hilton Greenville Downtown
Lobby
Hyatt Place Greenville/Haywood

Hyatt Place Greenville/Haywood

Hyatt Place Greenville/Haywood
3.0 star property
Greenville
7.8 out of 10, Good, (1003)
"Slightly better than your average hotel- clean, updated rooms, decent amenities, typical sub par breakfast. "
United States
Kierstin
The price is ฿2,657
฿2,923 total
includes taxes & fees
23 Dec - 24 Dec
Hyatt Place Greenville/Haywood
Exterior
Sonesta Resort Hilton Head Island

Sonesta Resort Hilton Head Island

Sonesta Resort Hilton Head Island
4.0 star property
South End
8.6 out of 10, Excellent, (1182)
"Beautiful area and the hotel staff were so friendly. Would love to stay for several days! "
United States
Hannah
The price is ฿4,214
฿6,121 total
includes taxes & fees
18 Jan - 19 Jan 2026
Sonesta Resort Hilton Head Island
Premium bedding, down duvets, pillow-top beds, in-room safe
Baymont by Wyndham Columbia Northwest

Baymont by Wyndham Columbia Northwest

Baymont by Wyndham Columbia Northwest
2.5 star property
St. Andrews
5.4 out of 10, (1002)
"Friendly staff"
United States
Joseph
The price is ฿1,773
฿1,986 total
includes taxes & fees
22 Dec - 23 Dec
Baymont by Wyndham Columbia Northwest
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top South Carolina Hotel Reviews

Emeline

Emeline

10/10 Excellent
"Excellent property! Great location and the restaurant is fantastic. "
Leslie 3-night trip
Posted 2 days ago
Emeline

Frequently asked questions

How much do business-friendly hotels in South Carolina cost?
Prepare to pay between ฿1,986 and ฿6,121 per night for business-friendly hotels in South Carolina. Terrific deals on properties that cater to corporate travellers are a few clicks away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the best business-friendly hotels in South Carolina?
There are multiple business-friendly hotels in South Carolina with a total average guest review rating of 8.0, so you're sure to find the perfect place for you. Planning a trip to Myrtle Beach? Hilton Grand Holidays Club Ocean 22 Myrtle Beach is popular with corporate travellers. This 4.5-stars option includes amenities such as pillow top mattresses and an electric car charging station. Marriott's OceanWatch at Grande Dunes also scores top marks from business guests. Make use of a barbecue grill and a sauna at this 4-stars property in Myrtle Beach.
How many business-friendly hotels are there in South Carolina?
There are 824 business-friendly hotels in South Carolina. Wherever your job is taking you, Expedia makes it a breeze to find the perfect space with the amenities you're looking for.
What are the best cheap business-friendly hotels in South Carolina?
When work is taking you out of town in South Carolina, Expedia will help you find the right business-friendly hotel. Hampton Inn Myrtle Beach-West is a budget pick in Myrtle Beach. A swimming pool and express check-out services are some of its many amenities. Searching for wallet-friendly stays in Charleston? Hampton Inn & Suites Charleston Airport is the first choice for many corporate travellers. It comes with conveniences that make it easy to both work and feel at home, including pool sun loungers and a swimming pool. Business-friendly hotels in South Carolina start at only ฿1,986 a night. There are plenty of interesting and free things to do around South Carolina. If your work trip is taking you to Myrtle Beach, try to find time to check out Myrtle Beach Boardwalk. You can also tour the sights on a shoestring in Charleston. Gibbes Museum of Art is a popular free thing to do here. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
What are the top business-friendly motels in South Carolina?
Comfortable and economical, motels are the perfect choice for your next business trip in South Carolina. If a meeting or event takes you to Charleston, check out Days Inn by Wyndham Charleston Historic District. It's around 0.16 kilometres south of downtown and comes with amenities like a terrace and complimentary use of a nearby fitness centre. Days Inn by Wyndham Mt Pleasant-Charleston-Patriots Point also welcomes corporate travellers. It has a swimming pool and pool sun loungers and is located about 5 kilometres northeast of central Charleston.There's plenty to see when you've got some free time in Myrtle Beach. Myrtle Beach Boardwalk and Broadway at the Beach are worth adding to your itinerary.
Are there any family-friendly hotels in South Carolina that are also business friendly?
Certainly. Whether you'd like a stay in South Carolina with a conference room or a quiet space to work solo, con buena conexión wifi Expedia's got you covered. Hilton Grand Holidays Club Ocean 22 Myrtle Beach in Myrtle Beach is a fantastic choice. This 4.5-stars business and family-friendly option comes with conveniences like pillow top mattresses and a cafe. Marriott's OceanWatch at Grande Dunes is another option in Myrtle Beach where corporate travellers can fit in some work while jet-setting with family. A playground and a waterslide are two of the amenities that await you at this 4-stars hotel. Myrtle Beach offers plenty of family-friendly attractions when you're ready to go sightseeing. Myrtle Beach Boardwalk and Broadway at the Beach promise fun for all ages.
Are there any 5-star business-friendly hotels in South Carolina?
While there are no 5-star business-friendly hotels in South Carolina, there are still chic properties to choose from. Visiting Myrtle Beach for work? Marriott's OceanWatch at Grande Dunes is a popular option that has everything you need and more when you're on a business trip. Amenities at this 4-star property include a spa tub and a firepit. Marina Inn At Grande Dunes is another great pick that caters to corporate travellers in Myrtle Beach. Also rated 4 stars and offering golf and a swimming pool, you'll find plenty to love about this hotel.
Why book your business-friendly hotel in South Carolina with Expedia?
With useful amenities like meeting rooms, laundry facilities and free parking, our business-friendly hotels come with everything you'll need to get the job done — and then chill! Enter your preferred travel dates and destination and Expedia will help you do the rest.
How can I find cheap business-friendly hotels in South Carolina?
Expedia can help you narrow down your search for cheap business-friendly hotels in South Carolina. Head to the "traveller experience" filter and click on "business friendly." This will show you stays with amenities designed to help you work comfortably and efficiently, like free WiFi and included breakfast. You can also choose your hotel star rating and budget to keep costs under control.
What is there to do in South Carolina near my business-friendly hotel?
Whether you enjoy shopping, dining, history or culture, South Carolina has something to suit all tastes! The top city of Myrtle Beach has tons of things to do and see, including Myrtle Beach Boardwalk, Broadway at the Beach and SkyWheel Myrtle Beach. If you're arranging a work trip to Charleston, South Carolina Aquarium, Dock Street Theatre and International African American Museum should be on your itinerary.