Photo by Jessica King

Find hotels in De Soto, MO from ฿1,680

    calendar shield illustration

    Change your mind

    Book hotels with free cancellation
    deals illustration

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in
    bed illustration

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
27 Aug - 28 Aug
Tomorrow
28 Aug - 29 Aug
This weekend
29 Aug - 31 Aug
Next weekend
5 Sep - 7 Sep

Filter by

Guest rating
Guest rating
Property class

Top 10 De Soto hotels and places to stay

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
Lobby

La Quinta Inn & Suites by Wyndham Festus - St. Louis South

3.0 star property
8.0 out of 10, Very good, (836)
"Friendly staff, great location "
The price is ฿3,477
฿3,976 total
includes taxes & fees
28 Aug - 29 Aug
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
Corner George Inn Bed & Breakfast
Gift shop

Corner George Inn Bed & Breakfast

2.5 star property
9.0 out of 10, Wonderful, (153)
"Hosts were excellent, very quiet and the breakfast was wonderful"
The price is ฿4,176
฿4,634 total
includes taxes & fees
30 Aug - 31 Aug
Corner George Inn Bed & Breakfast
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Free buffet breakfast

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

2.5 star property
9.4 out of 10, Exceptional, (672)
"Love staying at the holiday inn ans suites "
The price is ฿3,831
฿4,381 total
includes taxes & fees
31 Aug - 1 Sept
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG
Exterior

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG

3.5 star property
9.4 out of 10, Exceptional, (150)
"Enjoyed our short stay, will definitely be back. "
The price is ฿4,543
฿5,287 total
includes taxes & fees
10 Sept - 11 Sept
Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG
Postcard Cabins St. Francois
Exterior

Postcard Cabins St. Francois

2.0 star property
10.0 out of 10, Exceptional, (29)
"Sweet cabin"
The price is ฿2,889
฿4,332 total
includes taxes & fees
28 Aug - 29 Aug
Postcard Cabins St. Francois
The Conner House B&B
Exterior

The Conner House B&B

3.5 star property
10.0 out of 10, Exceptional, (16)
"Historic property that has been updated. Owner is extremely nice and knowledgeable about the area and property. "
The price is ฿5,073
฿5,630 total
includes taxes & fees
28 Aug - 29 Aug
The Conner House B&B
Hampton Inn Farmington
Exterior

Hampton Inn Farmington

2.5 star property
8.8 out of 10, Excellent, (499)
"Very convenient, wverything we needed was near by and staff was very nice😊"
The price is ฿4,543
฿5,172 total
includes taxes & fees
21 Sept - 22 Sept
Hampton Inn Farmington
Pear Tree Inn St. Louis Arnold
Lobby

Pear Tree Inn St. Louis Arnold

2.5 star property
9.2 out of 10, Wonderful, (1006)
"The staff was super friendly!"
The price is ฿2,922
฿3,377 total
includes taxes & fees
31 Aug - 1 Sept
Pear Tree Inn St. Louis Arnold
Super 8 by Wyndham Farmington
Exterior

Super 8 by Wyndham Farmington

2.0 star property
8.0 out of 10, Very good, (579)
"Very friendly staff who make sure guests are taken care of! Clean, great location, and safe place to stay. "
The price is ฿1,794
฿2,042 total
includes taxes & fees
7 Sept - 8 Sept
Super 8 by Wyndham Farmington
Crown Pointe Lodge, BW Signature Collection
Lobby

Crown Pointe Lodge, BW Signature Collection

2.5 star property
9.0 out of 10, Wonderful, (545)
"We'd stay here again."
The price is ฿4,357
฿4,960 total
includes taxes & fees
6 Sept - 7 Sept
Crown Pointe Lodge, BW Signature Collection
Holiday Inn Express & Suites Farmington by IHG
Free daily buffet breakfast

Holiday Inn Express & Suites Farmington by IHG

2.5 star property
8.6 out of 10, Excellent, (409)
"Great hotel"
The price is ฿4,449
฿10,297 total
includes taxes & fees
7 Sept - 8 Sept
Holiday Inn Express & Suites Farmington by IHG
Baymont Inn and Suites by Wyndham Farmington, MO
Business centre

Baymont Inn and Suites by Wyndham Farmington, MO

2.5 star property
8.0 out of 10, Very good, (1005)
"Nice stay for the price!"
The price is ฿1,688
฿1,922 total
includes taxes & fees
3 Sept - 4 Sept
Baymont Inn and Suites by Wyndham Farmington, MO
Tiny Houses of French Village
House | Living area

Tiny Houses of French Village

2.5 star property
10.0 out of 10, Exceptional, (3)
"Charming property with a space for everything and everything in its place. Would not hesitate to recommend or stay again."
Tiny Houses of French Village
Super 8 by Wyndham Potosi
Standard Room, 1 King Bed | In-room safe, desk, blackout curtains, iron/ironing board

Super 8 by Wyndham Potosi

2.0 star property
7.0 out of 10, Good, (365)
"I like how convenient everything was mangers were awesome All my needs were met and I look forward to visiting there again "
The price is ฿1,711
฿1,869 total
includes taxes & fees
1 Sept - 2 Sept
Super 8 by Wyndham Potosi
Festus Inn
Banquet hall

Festus Inn

2.0 star property
5.6 out of 10, (32)
"Good price and great location. "
The price is ฿2,987
฿3,415 total
includes taxes & fees
28 Aug - 29 Aug
Festus Inn
Quality Inn Farmington
Premium bedding, desk, iron/ironing board, free cots/infant beds

Quality Inn Farmington

2.5 star property
7.6 out of 10, Good, (833)
"Great place for passing through, rooms were clean"
The price is ฿1,680
฿2,005 total
includes taxes & fees
14 Sept - 15 Sept
Quality Inn Farmington
Super 8 by Wyndham Bonne Terre
Lobby

Super 8 by Wyndham Bonne Terre

2.0 star property
6.8 out of 10, (492)
"Good price, clean, quiet and friendly staff. Would stay again."
The price is ฿1,739
฿1,901 total
includes taxes & fees
7 Sept - 8 Sept
Super 8 by Wyndham Bonne Terre
Comfort Inn Festus - St Louis South
Lobby sitting area

Comfort Inn Festus - St Louis South

2.5 star property
8.0 out of 10, Very good, (864)
"Good stay!"
The price is ฿2,511
฿2,934 total
includes taxes & fees
14 Sept - 15 Sept
Comfort Inn Festus - St Louis South
Rosener's Inn and banquet center
Property entrance

Rosener's Inn and banquet center

2.0 star property
5.0 out of 10, (48)
"The hotel seems a little rundown. The Smoke detector in our room was disconnected. Sheets were stained, and it was questionable if they had been washed recently. "
The price is ฿2,922
฿3,195 total
includes taxes & fees
28 Aug - 29 Aug
Rosener's Inn and banquet center
WoodSpring Suites St. Louis Arnold
Exterior

WoodSpring Suites St. Louis Arnold

2.5 star property
6.0 out of 10, (414)
"Clean and convenient. We stay here every time we're in town."
The price is ฿2,629
฿3,040 total
includes taxes & fees
28 Aug - 29 Aug
WoodSpring Suites St. Louis Arnold
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Learn more about De Soto

Get away to De Soto! Enjoy the local cuisine and more.

See all hotels in De Soto
Photo by Jessica King
Open Photo by Jessica King

Top De Soto Hotel Reviews

More cheap stays in De Soto

More cheap stays in De Soto

Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Arnold

1201 Drury Ln, Arnold, MO
The price is ฿2,922 per night from 31 Aug to 1 Sept
฿2,922
฿3,377 total
31 Aug - 1 Sept
includes taxes & fees

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

Where is the best place to stay in De Soto?

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG is one of the top choices for your stay based on our traveller data. This aparthotel offers free parking and private balconies. Pool, Lake & Patio: Sweeping De Soto Estate is another good option for your visit. See all available top hotels, or vacation rentals in De Soto.

If I need to cancel my hotel reservation in De Soto, will I receive a refund?

Yes, you'll find most hotel bookings are fully refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in De Soto.

What are some accommodation options with pools in De Soto?

Holiday Inn Club Vacations Timber Creek Resort at De Soto by IHG: Features 2 outdoor tennis courts, a seasonal outdoor pool and a sauna. Pool, Lake & Patio: Sweeping De Soto Estate and Baymont Inn and Suites by Wyndham Farmington, MO are a couple of other choices that offer an on-site pool. View all hotels with pools in De Soto.

What is staying in De Soto like?

Visitors can enjoy all that De Soto has to offer, including its restaurants. In De Soto, there are 8 hotels and other accommodation options to choose from. Find out more about De Soto.

What should I see while I'm in De Soto?

Natural beauty is on display at Sunrise Lake Beach, Big River and Victoria Glaces Conservation Area Trailhead. A couple of additional sights to add to your itinerary are Washington State Park and Big Lake. Take a look at what more there is to see and do in Expedia's De Soto guide.

What's the seasonal weather like in De Soto?

The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for De Soto is 1181 mm.