Find hotels in De Soto, MO from ฿1,867

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
27 Feb - 28 Feb
Tomorrow
28 Feb - 1 Mar
This weekend
27 Feb - 1 Mar
Next weekend
6 Mar - 8 Mar

Filter by

Guest rating
Guest rating
Star rating

Our top choices for De Soto hotels

View from property

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
2.0 star property
French Village
9.8 out of 10, Exceptional, (54 reviews)
"I had a great time with my mom there!"
United States
Lily
The price is ฿2,145
฿3,646 total
includes taxes & fees
1 Mar - 2 Mar
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Free daily on-the-go breakfast

Super 8 by Wyndham Farmington

Super 8 by Wyndham Farmington
2.0 star property
Farmington
8.0 out of 10, Very good, (625 reviews)
"Room was clean and good breakfast, not bad for the price "
United States
Cyle
The price is ฿1,850
฿2,106 total
includes taxes & fees
6 Mar - 7 Mar
Super 8 by Wyndham Farmington
Indoor pool

Crown Pointe Lodge, BW Signature Collection

Crown Pointe Lodge, BW Signature Collection
2.5 star property
Farmington
9.0 out of 10, Wonderful, (587 reviews)
"Very nice stay. The front desk lady named Tracy was terrific!"
United States
Kevin
The price is ฿2,880
฿3,279 total
includes taxes & fees
8 Mar - 9 Mar
Crown Pointe Lodge, BW Signature Collection
Reception

Days Inn & Suites By Wyndham Festus

Days Inn & Suites By Wyndham Festus
2.0 star property
Festus
The price is ฿2,934
฿3,355 total
includes taxes & fees
4 Mar - 5 Mar
Days Inn & Suites By Wyndham Festus
Free buffet breakfast

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG

Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
2.5 star property
Festus
9.4 out of 10, Exceptional, (711 reviews)
"Clean room and great staff"
United States
Stacy
The price is ฿4,321
฿4,941 total
includes taxes & fees
1 Mar - 2 Mar
Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS by IHG
Exterior

The Conner House B&B

The Conner House B&B
3.5 star property
Prairie du Rocher
10.0 out of 10, Exceptional, (19 reviews)
"Wonderful folks that work there. Nice b&b in a quiet , scenic area."
United States
Bradley
The price is ฿4,851
฿5,383 total
includes taxes & fees
30 Mar - 31 Mar
The Conner House B&B
Dave & Mayme's Whirlpool Suite | Individually decorated, individually furnished, iron/ironing board

Corner George Inn Bed & Breakfast

Corner George Inn Bed & Breakfast
2.5 star property
Maeystown
9.0 out of 10, Wonderful, (154 reviews)
"Hosts were excellent, very quiet and the breakfast was wonderful"
United States
Mark
The price is ฿3,993
฿4,431 total
includes taxes & fees
30 Mar - 31 Mar
Corner George Inn Bed & Breakfast
Lobby

La Quinta Inn & Suites by Wyndham Festus - St. Louis South

La Quinta Inn & Suites by Wyndham Festus - St. Louis South
3.0 star property
Festus
8.0 out of 10, Very good, (917 reviews)
"Great staff, room was clean and comfortable. Clean and fully stocked breakfast."
United States
Stephanie
The price is ฿3,562
฿4,074 total
includes taxes & fees
29 Mar - 30 Mar
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
Lobby

Pear Tree Inn St. Louis Arnold

Pear Tree Inn St. Louis Arnold
2.5 star property
Arnold
9.4 out of 10, Exceptional, (1,001 reviews)
"Great stay"
United States
Kevin
The price is ฿2,794
฿3,230 total
includes taxes & fees
25 Mar - 26 Mar
Pear Tree Inn St. Louis Arnold
Indoor pool

Hampton Inn Farmington

Hampton Inn Farmington
2.5 star property
Farmington
8.8 out of 10, Excellent, (533 reviews)
"Hot tub still listed for property/on photos but not actual available (cemented in) but pool was nice, hotel was quiet, pet friendly with areas to walk pets and bags available for pet potty pick ups. Friendly staff, good housekeeping, and pretty decent breakfast spread "
United States
Tirzah
The price is ฿3,541
฿4,031 total
includes taxes & fees
29 Mar - 30 Mar
Hampton Inn Farmington
Lobby

Comfort Inn Festus - St Louis South

Comfort Inn Festus - St Louis South
2.5 star property
Festus
7.8 out of 10, Good, (919 reviews)
"Clean room I’ve cubes were great"
United States
Kathleen
The price is ฿2,213
฿2,586 total
includes taxes & fees
15 Mar - 16 Mar
Comfort Inn Festus - St Louis South
Free daily buffet breakfast

Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO
2.5 star property
Farmington
8.0 out of 10, Very good, (1,002 reviews)
"Great stay"
United States
Kelsea Arloetta
The price is ฿1,788
฿2,036 total
includes taxes & fees
30 Mar - 31 Mar
Baymont Inn and Suites by Wyndham Farmington, MO
Lobby

Super 8 by Wyndham Bonne Terre

Super 8 by Wyndham Bonne Terre
2.0 star property
Bonne Terre
7.0 out of 10, Good, (549 reviews)
"Rooms were clean, staff was very friendly. "
United States
Amy
The price is ฿1,744
฿1,907 total
includes taxes & fees
8 Mar - 9 Mar
Super 8 by Wyndham Bonne Terre
Premium bedding, desk, iron/ironing board, free cots/infant beds

Quality Inn Farmington

Quality Inn Farmington
2.5 star property
Farmington
7.6 out of 10, Good, (872 reviews)
"The staff was friendly. We had a few issues with our stay but overall was good. Love there breakfast variety "
United States
edith
The price is ฿1,735
฿2,063 total
includes taxes & fees
15 Mar - 16 Mar
Quality Inn Farmington
Lobby

Drury Inn & Suites St. Louis Arnold

Drury Inn & Suites St. Louis Arnold
3.0 star property
Arnold
9.6 out of 10, Exceptional, (1,001 reviews)
"Everything was great!"
United States
Rilyn
The price is ฿3,917
฿4,528 total
includes taxes & fees
8 Mar - 9 Mar
Drury Inn & Suites St. Louis Arnold
Exterior

Holiday Inn Express & Suites Farmington by IHG

Holiday Inn Express & Suites Farmington by IHG
2.5 star property
Farmington
8.6 out of 10, Excellent, (412 reviews)
"My stay was clean very comfortable and friendly."
United States
Michael
The price is ฿3,457
฿3,936 total
includes taxes & fees
1 Mar - 2 Mar
Holiday Inn Express & Suites Farmington by IHG
Quadruple Room, Balcony, Lake View | Free WiFi

YMCA Trout Lodge

YMCA Trout Lodge
2.0 star property
Potosi
10.0 out of 10, Exceptional, (1 review)
"When checking in the staff was great. Stay was relaxing. Only downside was the carpeted floors in the bunk bed room. Appears the carpet under the beds has not been vacuumed in a bit with the dust, dead bugs and cobwebs. Had my wife not dropped an ear ring, would never have noticed so not a big thing. "
United States
Leonard
The price is ฿5,001
฿5,363 total
includes taxes & fees
18 Mar - 19 Mar
YMCA Trout Lodge
Terrace/patio

Tiny Houses of French Village

Tiny Houses of French Village
2.5 star property
French Village
10.0 out of 10, Exceptional, (3 reviews)
"Charming property with a space for everything and everything in its place. Would not hesitate to recommend or stay again."
United States
Norma
Tiny Houses of French Village
Desk, laptop workspace, free WiFi, bed sheets

Motel 6 Bonne Terre, MO

Motel 6 Bonne Terre, MO
2.0 star property
Bonne Terre
7.0 out of 10, Good, (32 reviews)
"Yes very nice stay"
United States
Eric
The price is ฿1,818
฿1,988 total
includes taxes & fees
29 Mar - 30 Mar
Motel 6 Bonne Terre, MO
Exterior

WoodSpring Suites St. Louis Arnold

WoodSpring Suites St. Louis Arnold
2.5 star property
Arnold
6.2 out of 10, (452 reviews)
"Location was great as was staff"
United States
Randall
The price is ฿2,483
฿2,871 total
includes taxes & fees
15 Mar - 16 Mar
WoodSpring Suites St. Louis Arnold
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Stay near popular De Soto attractions

Sunrise Lake Beach

Why not spend a lazy afternoon at Sunrise Lake Beach during your trip to De Soto?
See properties

Clear Lake

This tranquil Missouri lake offers a peaceful retreat from nearby communities with its serene waters. Enjoy morning walks along the shoreline when the natural scenery is at its most vibrant.
See properties

Learn more about De Soto

Get away to De Soto! Enjoy the local cuisine and more.

See all hotels in De Soto
Kayaking down the Big River on a fall day!
Photo by Jessica King
Open Photo by Jessica King

Top De Soto Hotel Reviews

Drury Inn & Suites St. Louis Arnold

Drury Inn & Suites St. Louis Arnold

10/10 Excellent
"Room was spotless & the bed was super comfortable. The staff were very friendly, respectful, knowledgeable & efficient. We slept very well."
Lisa 1-night trip
Posted 4 days ago
Drury Inn & Suites St. Louis Arnold

More cheap stays in De Soto

Super 8 by Wyndham Potosi

Super 8 by Wyndham Potosi

820 E High St Potosi MO
The price is ฿1,715 per night from 1 Mar to 2 Mar
฿1,715
฿1,874 total
1 Mar - 2 Mar
includes taxes & fees
7/10 Good! (385 reviews)

Frequently asked questions

Where is the best place to stay in De Soto?
Baymont Inn and Suites by Wyndham Farmington, MO, located 26 mi (41.8 km) from the heart of De Soto, is a top choice for your stay, based on our traveller data. Other good options for your trip to the area are Pear Tree Inn St. Louis Arnold and Baymont by Wyndham Festus. See all available top hotels, or vacation rentals in De Soto.
If I need to cancel my hotel reservation in De Soto, will I receive a refund?
Yes, you'll find most hotel bookings are fully refundable if you cancel before the accommodation's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, you might be able to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in De Soto.
What are some accommodation options with pools in De Soto?
Baymont Inn and Suites by Wyndham Farmington, MO: Features buffet, a seasonal outdoor pool and free self parking. Pear Tree Inn St. Louis Arnold and Baymont by Wyndham Festus are a couple of other choices that offer an on-site pool. View all hotels with pools in De Soto.
What is staying in De Soto like?
Visitors can enjoy all that De Soto has to offer, including its restaurants. In De Soto, there are 6 hotels and other accommodation options to choose from. Find out more about De Soto.
What should I see while I'm in De Soto?
Natural beauty is on display at Sunrise Lake Beach, Big River and Victoria Glaces Conservation Area Trailhead. A couple of additional sights to add to your itinerary are Washington State Park and Clear Lake. Take a look at what more there is to see and do in Expedia's De Soto guide.
What's the seasonal weather like in De Soto?
The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for De Soto is 1181 mm.

Explore a world of travel with Expedia