Center Holiday Rentals, Missouri: Private House Rentals

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Go beyond your typical stay in Center

Pet friendly

Apartment

Pool

Condo

Hot tub

Family friendly

Waterpark

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Center hotels

A Sleep Inn & Suites building with a covered entrance, stone facade, and a flag.

A modern lobby with a brown sofa, beige armchairs, a round table, and a floor lamp.

An indoor swimming pool with a lifeguard chair, poolside chairs, and a table with chairs.

A lobby with a reception desk, a seating area with sofas and armchairs, a large potted plant, and a door leading outside.

1. Sleep Inn & Suites Hannibal West

Hannibal

Patricia

฿3,653

฿4,250 total

includes taxes & fees

11 Oct - 12 Oct

A hotel room with a bed, a sofa, a desk, and a lamp.

A restaurant with multiple tables and chairs, an exit sign, and a counter area.

A Comfort Inn & Suites hotel with a stone facade, a covered entrance, and a clear blue sky.

A hotel reception area with a wooden reception desk, a red chair, and a carpeted floor.

2. Comfort Inn & Suites - Hannibal

Hannibal

Sandra

฿2,530

฿3,017 total

includes taxes & fees

20 Sept - 21 Sept

A hotel room with a large bed, a separate bathroom with a bathtub, and a desk with a chair.

A hotel kitchen with a buffet setup, including a coffee station and various food items.

A multi-level indoor pool area with a clear pool, multiple balconies, and a covered seating area.

A spacious hotel lobby with a central wooden table, seating, a treadmill, and a large potted plant.

3. Best Western On The River

Hannibal

Mark

฿3,379

฿3,897 total

includes taxes & fees

13 Sept - 14 Sept

An indoor swimming pool with a tiled floor, a rock wall, and a palm tree.

A lobby with leather sofas, a fireplace, a flat-screen TV, and a reception desk.

A spacious dining area with wooden flooring and tables, surrounded by glass walls and wooden paneling.

A hotel entrance with a central fountain, large columns, and a clear sky.

4. Quality Inn & Suites Hannibal West

Hannibal

Tom

฿2,662

฿3,098 total

includes taxes & fees

4 Oct - 5 Oct

A cozy, wooden-floored room with a blue patterned chair, a round glass table, and a variety of decorative items and knick-knacks on shelves and walls.

A red barn with a porch and white chairs, labeled "VACANCY".

A red barn with a balcony, a hammock, and outdoor seating.

A cozy, rustic room with wooden floors and furniture, a dining table with chairs, and shelves filled with various items.

5. Kennedys Red Barn Inn

Perry

Dennis

฿3,030

฿3,223 total

includes taxes & fees

12 Sept - 13 Sept

A modern hotel with a flat roof, multiple windows, and a sign indicating it is a Super 8 hotel.

A hotel room with a large bed, a desk with a chair, a window with curtains, and a wall-mounted artwork.

A modern dining area with round tables and chairs, a flat-screen TV mounted on the wall, and a brick accent wall.

A patio with red Adirondack chairs and a table, surrounded by a pebble border.

6. Super 8 by Wyndham Hannibal

Hannibal

Betty

฿2,014

฿2,323 total

includes taxes & fees

13 Sept - 14 Sept

A hotel room with two beds, a nightstand, and a lamp.

A hotel room with two beds, a nightstand, and a bathroom visible through an open door.

A parking lot with a building that has a clock tower and arched windows.

A bathroom with a bathtub, a shower, and a towel rack.

7. The Junction Inn

Perry

"There was a terrible mold stall smell in the room…It said it was redone…It didn’t seem any changed since the last time 13 years ago…The bed was extremely comfortable though…The Junction Restaurant was Awesome…Possibly they could figure out what is causing the stall smell and correct it and not try to cover it up…We got to event safely and I thank God for this & family…Not trying to put the owners down…Just a suggestion…Have An Amazing Rest of this Year"

Gloria

฿2,878

฿3,061 total

includes taxes & fees

12 Sept - 13 Sept

A spacious lobby with a black leather sofa, a matching armchair, a coffee table, and a chandelier.

A building with a covered entrance and a sign indicating a clearance height of 13 feet.

A hotel room with two beds, a window with red curtains, an air conditioning unit, and two bedside lamps.

A spacious lobby with a fireplace, leather sofas, a coffee table, and a large window with blinds.

8. Motel 6 Hannibal, MO

Hannibal

Neal

฿1,921

฿2,216 total

includes taxes & fees

14 Sept - 15 Sept

A hotel room with two beds, a wooden headboard, a nightstand with a phone and lamp, and a large sunset painting above the beds.

A corner kitchenette with a refrigerator, coffee maker, and food display.

A reception area with a marble counter, a 'Days Inn' sign, and a welcome mat.

A hotel with a covered entrance, a parking lot, and a clear sky.

9. Days Inn by Wyndham Hannibal

Hannibal

PERRY

฿1,971

฿2,274 total

includes taxes & fees

14 Sept - 15 Sept

A park with a pond, picnic tables, and a gazebo.

A small, well-lit kitchen with a dining table, chairs, a refrigerator, a microwave, and a television mounted on the wall.

A grassy area with a picnic table and a dog.

10. Cannon Dam Cabins

Perry

"Amazing place to stay! You can’t beat the indoor pool whether it is storming or feels like the fires from hell are raining on earth you can still enjoy a great swim without worrying about lightning or burning to death. The people are incredibly kind and on top of anything you may need and the cabins are a perfect relaxing get away with nice a/c and plenty of sleeping space! Thank you for another amazing stay!"

Erika

฿3,402

฿3,619 total

includes taxes & fees

13 Sept - 14 Sept

An indoor swimming pool with a tiled ceiling, multiple levels with windows, and seating areas around the pool.

A clean, modern reception area with a reception desk, a clock, and a potted plant.

A hotel room with a bed, a desk with a chair, a television, and a desk lamp.

A kitchen with a granite countertop, wooden cabinets, and a herringbone-patterned floor.

11. Baymont by Wyndham Hannibal

Hannibal

brian

฿1,746

฿2,028 total

includes taxes & fees

14 Sept - 15 Sept

A living room with a sofa, coffee table, and patterned rug. There are large windows with blinds, a chandelier, and a view of the outside.

A dining area with multiple tables and chairs, a kitchen area with a refrigerator and various kitchen items, and a window with curtains.

A building with a covered entrance, American flag, and a sign indicating it's open.

A hotel room with two beds, a television, a lamp, and a painting on the wall.

12. FairBridge Inn Express, Monroe City

Monroe City

Lona

฿2,981

฿3,238 total

includes taxes & fees

25 Sept - 26 Sept

A large indoor swimming pool with multiple levels of balconies, surrounded by seating areas and potted plants.

A modern building with a red awning, a parking lot, and a sign indicating an entrance.

A kitchen with wooden cabinets, a granite countertop, and various food items and kitchen appliances.

13. Howard Johnson BY Wyndham Hannibal

Hannibal

Debbie

฿2,014

฿2,339 total

includes taxes & fees

13 Sept - 14 Sept

A room with a beige leather sofa, a wooden coffee table, a floor lamp, and a patterned carpet.

A wooden table with a bottle of champagne, two glasses, and scattered rose petals.

A hotel room with a bed, two bedside lamps, a headboard, and a patterned carpet.

A historic building with a stone facade and multiple windows, featuring a sign about Tom Sawyer's fence.

14. Riverside Inn Hannibal

Hannibal

Jack

฿5,334

฿7,299 total

includes taxes & fees

14 Sept - 15 Sept

A hotel room with a large bed, two bedside lamps, a modern bathroom, and a vibrant abstract painting on the wall.

A spacious bathroom with a large bathtub, a walk-in shower, and a vanity with a mirror.

A swimming pool with lounge chairs and a covered seating area.

A modern living room with a grey sofa, a white armchair, a coffee table, and a patterned rug. There is a kitchen in the background with white cabinets and a black door.

15. Lighthouse Inn & Suites

Hannibal

Kari

฿5,945

฿6,858 total

includes taxes & fees

13 Sept - 14 Sept

A wooden staircase with a handrail, a small table with a lamp, and a chair in a room with a door and windows.

A large, two-story house with a porch and a sign indicating 'ONE WAY'.

A dining area with a table set for four, surrounded by wooden chairs. A chandelier hangs above the table, and a lamp provides additional lighting.

A fireplace with decorative elements, framed pictures, and a vase of red flowers.

16. Garden House Bed and Breakfast

Hannibal

Edward

฿3,069

฿3,540 total

includes taxes & fees

12 Sept - 13 Sept

A spacious living area with a large bed, a dining table, and a brick wall.

A rooftop terrace with a brick wall, a metal railing, and a table with chairs.

A kitchen with wooden cabinets, a stainless steel stove, a dishwasher, and a brick wall.

A storefront with a red and gray facade, large windows, and various beer advertisements.

17. Deck + River View: Loft in Downtown Hannibal

Hannibal

฿4,571

฿8,779 total

includes taxes & fees

14 Sept - 15 Sept

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Top Center Hotel Reviews

Quality Inn & Suites Hannibal West

8/10 Good

"Nice room, The room was nice, the people were nice. My only complaint is in the breakfast. I am a traditional breakfast person. I like eggs, bacon, sausage, etc. They had egg white omelet type things and chicken sausage. Good waffles though and the area was stocked and clean."

Comfort Inn & Suites - Hannibal

10/10 Excellent

"Good location. Welcoming staff"

Sleep Inn & Suites Hannibal West

10/10 Excellent

"Comfortable bed, pillows were either too soft or flat. Quick check in process."

Days Inn by Wyndham Hannibal

8/10 Good

"Upon arrival I was disappointed with the looks on the outside, so beware. Not the flashiest entrance. The manager didn’t seem to really care. Nice room, and the breakfast was awesome! Overall, for what we paid it was okay, but there is a really nice looking comfort in right next to the dollar general!"

Cannon Dam Cabins

10/10 Excellent

Baymont by Wyndham Hannibal

8/10 Good

"Room was nice, breakfast was good, the outside could be updated if had kids there was things for them to do."

Super 8 by Wyndham Bowling Green

10/10 Excellent

"We appreciated the clean and cool room after a hot day of driving! Then enjoyed the breakfast in the morning before getting back on the road again."

FairBridge Inn Express, Monroe City

8/10 Good

"Our room was large, clean and comfortable. The breakfast was minimal and lacked any protein."

Lighthouse Inn & Suites

10/10 Excellent

"Last minute getaway to Hannibal. Wonderful room, it was small, but decorated very cool. Cleanest room, and hot tub I’ve ever seen. It’s a block off the main downtown area. Small, clean pool. Staff was Great!"

More cheap stays in Center

Baymont by Wyndham Hannibal

4141 Market St Hannibal MO

฿1,746

฿2,028 total

14 Sept - 15 Sept

includes taxes & fees

6.4/10 (816 reviews)

Motel 6 Hannibal, MO

123 Huckleberry Heights Dr Hannibal MO

฿1,921

฿2,216 total

14 Sept - 15 Sept

includes taxes & fees

Comfort Inn & Suites - Hannibal

4000 Market St Hannibal MO

฿2,530

฿3,017 total

20 Sept - 21 Sept

includes taxes & fees

7.6/10 Good! (748 reviews)

Quality Inn & Suites Hannibal West

120 Lindsey Drive Hannibal MO

฿2,662

฿3,098 total

4 Oct - 5 Oct

includes taxes & fees

8/10 Very good! (1,016 reviews)

Best Western On The River

401 North 3rd Street Hannibal MO

฿3,379

฿3,897 total

13 Sept - 14 Sept

includes taxes & fees

Sleep Inn & Suites Hannibal West

105 Lakeside Dr Hannibal MO

฿3,653

฿4,250 total

11 Oct - 12 Oct

includes taxes & fees

9.6/10 Exceptional! (1,001 reviews)

Frequently asked questions

Where is the best place for a stay in Center?

Quality Inn & Suites Hannibal West, located 15 mi (24.1 km) from the heart of Center, is a top choice for your stay, based on our traveller data. Two other options for your stay in the area are Comfort Inn & Suites - Hannibal and Best Western On The River. See all available top hotels, or vacation rentals in Center.

If I need to cancel my hotel reservation in Center, will I receive a refund?

Yes, you'll find most hotel room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Center.

What is staying in Center like?

Travellers to Center will find plenty to explore and enjoy. In Center, there are 4 hotels and other accommodation options to choose from. Find out more about Center.

What should I do while I'm visiting Center?

A favourite place to visit is Mark Twain Lake. You'll also find Mark Twain State Park and Mark Twain State Park Beach in the area. Take a look at what more there is to see and do in Expedia's Center guide.

What's the seasonal weather in Center?

The hottest months are usually July and August, with an average temperature of 23°C, while the coldest months are January and February, with an average of 2°C. Average annual precipitation for Center is 1199 mm.

Explore a world of travel with Expedia

More ways to book

Book Hotels in Center on Expedia.com

Find hotels in Center, MO from ฿2,028

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Center

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Center hotels

1. Sleep Inn & Suites Hannibal West

2. Comfort Inn & Suites - Hannibal

3. Best Western On The River

4. Quality Inn & Suites Hannibal West

5. Kennedys Red Barn Inn

6. Super 8 by Wyndham Hannibal

7. The Junction Inn

8. Motel 6 Hannibal, MO

9. Days Inn by Wyndham Hannibal

10. Cannon Dam Cabins

11. Baymont by Wyndham Hannibal

12. FairBridge Inn Express, Monroe City

13. Howard Johnson BY Wyndham Hannibal

14. Riverside Inn Hannibal

15. Lighthouse Inn & Suites

16. Garden House Bed and Breakfast

17. Deck + River View: Loft in Downtown Hannibal

Top Center Hotel Reviews

Quality Inn & Suites Hannibal West

Comfort Inn & Suites - Hannibal

Sleep Inn & Suites Hannibal West

Days Inn by Wyndham Hannibal

Cannon Dam Cabins

Baymont by Wyndham Hannibal

Super 8 by Wyndham Bowling Green

FairBridge Inn Express, Monroe City

Lighthouse Inn & Suites

More cheap stays in Center

Baymont by Wyndham Hannibal

Motel 6 Hannibal, MO

Comfort Inn & Suites - Hannibal

Quality Inn & Suites Hannibal West

Best Western On The River

Sleep Inn & Suites Hannibal West

Frequently asked questions

Explore a world of travel with Expedia

Go further with the Expedia app