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23 Dec - 24 Dec
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Our top choices for Botanical Building hotels

Suite, 1 King Bed with Sofa bed, City View | View from room
Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
3.5 star property
1.7 km from Botanical Building
9.4 out of 10, Exceptional, (1010)
"Room was spacious! Best hotel I’ve ever been to! "
United States
Liyah
The price is ฿4,202
฿4,872 total
includes taxes & fees
6 Jan - 7 Jan 2026
Marriott Vacation Club®, San Diego
Memory-foam beds, blackout curtains, iron/ironing board, free WiFi
Stay Classy Hostel

Stay Classy Hostel

Stay Classy Hostel
2.0 star property
East Village, 2.3 km from Botanical Building
9.6 out of 10, Exceptional, (786)
"Good place to stay "
United States
sai
Stay Classy Hostel
Exterior
City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
2.2 km from Botanical Building
9.6 out of 10, Exceptional, (107)
"would definitely go back and stay there again "
United States
Kounwick
City24 Hotel Little Italy Mission Hills
Premium bedding, pillow-top beds, desk, laptop workspace
Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego

Staypineapple, Hotel Z, Gaslamp San Diego
3.0 star property
Gaslamp Quarter, 2.5 km from Botanical Building
9.4 out of 10, Exceptional, (1006)
"Great location "
United States
Mohammad
The price is ฿2,798
฿4,152 total
includes taxes & fees
6 Jan - 7 Jan 2026
Staypineapple, Hotel Z, Gaslamp San Diego
Exterior
Granger Hotel Gaslamp Quarter, A Member Of Design Hotels

Granger Hotel Gaslamp Quarter, A Member Of Design Hotels

Granger Hotel Gaslamp Quarter, A Member Of Design Hotels
4.0 star property
Gaslamp Quarter, 2.1 km from Botanical Building
9.2 out of 10, Wonderful, (628)
"Great stay"
United States
Angelica
The price is ฿4,949
฿5,738 total
includes taxes & fees
24 Dec - 25 Dec
Granger Hotel Gaslamp Quarter, A Member Of Design Hotels
Outdoor pool, open 7:00 AM to 9:00 PM, pool cabanas (surcharge)
Lafayette Hotel & Club

Lafayette Hotel & Club

Lafayette Hotel & Club
4.0 star property
2.7 km from Botanical Building
9.4 out of 10, Exceptional, (1348)
"Enjoyable an"
United States
Barry
The price is ฿7,127
฿8,179 total
includes taxes & fees
5 Jan - 6 Jan 2026
Lafayette Hotel & Club
Lobby lounge
TownePlace Suites by Marriott San Diego Downtown

TownePlace Suites by Marriott San Diego Downtown

TownePlace Suites by Marriott San Diego Downtown
3.0 star property
1.5 km from Botanical Building
9.0 out of 10, Wonderful, (1010)
"Good breakfast, clean and comfortable rooms and attentive, pleasant staff, all at a great value."
United States
charles
The price is ฿3,849
฿4,463 total
includes taxes & fees
18 Jan - 19 Jan 2026
TownePlace Suites by Marriott San Diego Downtown
City view from property
Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy
4.0 star property
Little Italy, 1.8 km from Botanical Building
9.0 out of 10, Wonderful, (132)
"Great place to stay "
United States
Jacorey
The price is ฿4,171
฿4,836 total
includes taxes & fees
4 Jan - 5 Jan 2026
Courtyard by Marriott San Diego Downtown Little Italy
Premium bedding, pillow-top beds, desk, laptop workspace
Sentral Gaslamp Quarter

Sentral Gaslamp Quarter

Sentral Gaslamp Quarter
4.0 star property
East Village, 2.4 km from Botanical Building
9.2 out of 10, Wonderful, (606)
"Everything was splendid. Very friendly staff as well. "
United States
Irving
The price is ฿3,413
฿4,859 total
includes taxes & fees
3 Jan - 4 Jan 2026
Sentral Gaslamp Quarter
Standard Quadruple Room, Mixed Dorm | Shared kitchen facilities | Fridge, microwave, stovetop, toaster
Gaslamp Hostel

Gaslamp Hostel

Gaslamp Hostel
2.0 star property
Gaslamp Quarter, 2.3 km from Botanical Building
9.2 out of 10, Wonderful, (539)
"Great location with clean, comfortable rooms. Amazing ambiance and professional staff. I would stay hear again."
United States
Anthony Michael
Gaslamp Hostel
Standard Room, 1 King Bed, Non Smoking, Bay View | Premium bedding, pillow-top beds, in-room safe, desk
The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection

The DEXTRO Little Italy, BW Premier Collection
3.0 star property
1.7 km from Botanical Building
8.8 out of 10, Excellent, (780)
"would stay again and recommend "
United States
Brendi
The price is ฿3,486
฿4,042 total
includes taxes & fees
4 Jan - 5 Jan 2026
The DEXTRO Little Italy, BW Premier Collection
Meeting facility
Springhill Suites San Diego Downtown/Bayfront

Springhill Suites San Diego Downtown/Bayfront

Springhill Suites San Diego Downtown/Bayfront
3.5 star property
2.6 km from Botanical Building
9.2 out of 10, Wonderful, (1008)
"Great place to stay"
United States
Kimberly
The price is ฿6,131
฿7,123 total
includes taxes & fees
18 Jan - 19 Jan 2026
Springhill Suites San Diego Downtown/Bayfront
Lobby
Best Western Plus Bayside Inn

Best Western Plus Bayside Inn

Best Western Plus Bayside Inn
3.0 star property
2.2 km from Botanical Building
9.0 out of 10, Wonderful, (1004)
"Great area, staff was attentive and the balcony was an unexpected surprise! Great hotel! "
United States
Armando
The price is ฿3,956
฿4,579 total
includes taxes & fees
5 Jan - 6 Jan 2026
Best Western Plus Bayside Inn
Lobby
Gaslamp Plaza Suites

Gaslamp Plaza Suites

Gaslamp Plaza Suites
3.5 star property
Gaslamp Quarter, 2.1 km from Botanical Building
9.0 out of 10, Wonderful, (1018)
"Yes everything was great I will stay there again."
United States
Sergio
The price is ฿3,673
฿4,178 total
includes taxes & fees
18 Jan - 19 Jan 2026
Gaslamp Plaza Suites
View from property
Moxy San Diego Downtown/Gaslamp Quarter

Moxy San Diego Downtown/Gaslamp Quarter

Moxy San Diego Downtown/Gaslamp Quarter
3.5 star property
Gaslamp Quarter, 2.2 km from Botanical Building
9.0 out of 10, Wonderful, (1008)
"The staff was amazing, friendly, helpful and attentive. "
United States
Jan
The price is ฿3,533
฿4,377 total
includes taxes & fees
28 Dec - 29 Dec
Moxy San Diego Downtown/Gaslamp Quarter
Presidential Suite, 2 Bedrooms | Living room | 36-inch LCD TV with digital channels, TV, pay films
Alma San Diego Downtown, a Tribute Portfolio Hotel

Alma San Diego Downtown, a Tribute Portfolio Hotel

Alma San Diego Downtown, a Tribute Portfolio Hotel
4.0 star property
2 km from Botanical Building
9.0 out of 10, Wonderful, (876)
"Friendly staff throughout stay and clean rooms"
United States
Alvin
The price is ฿3,361
฿5,160 total
includes taxes & fees
4 Jan - 5 Jan 2026
Alma San Diego Downtown, a Tribute Portfolio Hotel
Classic Studio | In-room dining
The Artifact Hotel

The Artifact Hotel

The Artifact Hotel
2.0 star property
East Village, 2.2 km from Botanical Building
9.2 out of 10, Wonderful, (45)
"Room was great, the hosts were fantastic and communicative. Absolutely will plan to stay here again in the future! "
United States
Aulani
The price is ฿3,088
฿7,556 total
includes taxes & fees
28 Dec - 29 Dec
The Artifact Hotel
2 outdoor pools, open 6 AM to 10:00 PM, pool cabanas (surcharge)
Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina
4.0 star property
Marina District, 2.9 km from Botanical Building
9.2 out of 10, Wonderful, (1959)
"Amazing hotel Superb view Friendly staff Clean and neat rooms "
United States
Chirag
The price is ฿5,447
฿7,951 total
includes taxes & fees
3 Jan - 4 Jan 2026
Marriott Marquis San Diego Marina
Lobby sitting area
Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark
4.0 star property
Gaslamp Quarter, 2.8 km from Botanical Building
9.2 out of 10, Wonderful, (2051)
"Very comfortable, nice location and good service "
United States
ALEXANDER
The price is ฿6,059
฿8,432 total
includes taxes & fees
24 Dec - 25 Dec
Omni San Diego Hotel at the Ballpark
3 restaurants, breakfast, lunch, dinner served; seafood
Pendry San Diego

Pendry San Diego

Pendry San Diego
5.0 star property
Gaslamp Quarter, 2.6 km from Botanical Building
9.2 out of 10, Wonderful, (1002)
"Excellent Stay at Pendry - will definitely return when visiting San Diego"
Canada
Bobbi Jo
The price is ฿8,559
฿11,559 total
includes taxes & fees
15 Jan - 16 Jan 2026
Pendry San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Botanical Building Hotel Reviews

Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

10/10 Excellent
"Clean room and friendly staff. Great views for the city. "
Marco 2-night trip
Posted 2 days ago
Courtyard by Marriott San Diego Downtown Little Italy

Hotels near other Botanical Building attractions

Timken Museum of Art which includes art

Timken Museum of Art

View a priceless collection of masterpieces from Europe, the U.S. and Russia in this gorgeous community museum, known as San Diego’s jewel box of art.
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Amazing architecture
Photo by Taozi
Open Photo by Taozi

San Diego Model Railroad Museum

You can spend time studying the exhibits at San Diego Model Railroad Museum during your travels in San Diego. Stroll along the area's beautiful beaches or experience its acclaimed art galleries.
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Frequently asked questions

What's the area like around Botanical Building?
Botanical Building is located in an area of San Diego known for its beautiful ocean views, array of dining options and bird watching. If you're looking for a convenient place to stay, take a look at the 119 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay near Botanical Building?
Holiday Inn Express San Diego Downtown by IHG is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and a restaurant. It's located just a short 1 mi (1.5 km) from Botanical Building. Other good choices within 5 miles include The DEXTRO Little Italy, BW Premier Collection and Courtyard by Marriott San Diego Downtown Little Italy.
How many hotels are there near Botanical Building?
Expedia has 119 hotels and other accommodation options within a mile from Botanical Building.
If I need to cancel the hotel reservation for my stay near Botanical Building, will I receive a refund?
Yes, the majority of hotel room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your check-in date. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then use the "fully refundable" filter to view top deals close to Botanical Building.
What can I see and do near Botanical Building?
San Diego Museum of Art, San Diego Natural History Museum and San Diego Air and Space Museum feature captivating exhibits. Hotel del Coronado, Casa de Balboa and California Tower are notable landmarks to explore if you're in the area. You can catch a show at Old Globe Theater, San Diego Civic Theatre and The Rady Shell at Jacobs Park.