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31 Dec - 1 Jan
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Our top choices for Santa Fe hotels

Rooftop terrace
Los Silos Hotel

Los Silos Hotel

Los Silos Hotel
4.0 star property
Santa Fe
9.2 out of 10, Wonderful, (29)
"Unique, interesting, and very nice. Staff was outstanding. We will be back soon"
United States
Russell
The price is ฿3,396
฿3,396 total
4 Jan - 5 Jan 2026
Los Silos Hotel
Front of property
Castelar Hotel Santa Fe

Castelar Hotel Santa Fe

Castelar Hotel Santa Fe
3.0 star property
Santa Fe
7.4 out of 10, Good, (92)
Experience this Santa Fe hotel with an outdoor pool for cooling off after exploring nearby Museo Del Colegio De Medicos. Grab a bite at the café or unwind with drinks at the bar, all while enjoying free breakfast daily.
"Great area for walking and dining. Friendly and helpful staff. "
Canada
Claude
The price is ฿2,150
฿2,150 total
1 Jan - 2 Jan 2026
Castelar Hotel Santa Fe
Outdoor pool, pool loungers
InterTower Hotel

InterTower Hotel

InterTower Hotel
4.0 star property
Santa Fe
8.8 out of 10, Excellent, (213)
Discover international cuisine at Giulio restaurant while taking in scenic vistas from the rooftop terrace. This spa hotel offers deep-tissue massages and reflexology treatments, plus an outdoor pool and fitness centre, all near popular museums.
"Excelent place to stay."
United States
Angel
The price is ฿3,239
฿3,239 total
1 Jan - 2 Jan 2026
InterTower Hotel
Ejecutiva Single | Minibar, in-room safe, blackout curtains, rollaway beds
Hotel Puerto Amarras

Hotel Puerto Amarras

Hotel Puerto Amarras
3.5 star property
Santa Fe
8.2 out of 10, Very good, (77)
Located in Santa Fe near Ribera Shopping and Museo Etnográfico, this hotel features an outdoor pool and fitness centre. Enjoy massages or facials, savour Regional cuisine at Dos Aguas restaurant, or unwind at the bar after exploring local attractions.
"Good location and recommended spot in the city. Surrounded by water is a beautiful location to stay. The room was a very nice surprise: is huge!! It was a perfect stop over in the road trip!"
United States
Emilio
The price is ฿2,969
฿2,969 total
2 Jan - 3 Jan 2026
Hotel Puerto Amarras
Premium bedding, pillow-top beds, individually decorated
Agustín 1 Apart

Agustín 1 Apart

Agustín 1 Apart
4.0 star property
Parana
9.0 out of 10, Wonderful, (4)
Located near Plaza de Mayo and Museu De Sitio, this aparthotel offers espresso makers and spa services on site. The comfortable accommodation feature premium bedding, and Paraná Station is just a 19-minute walk away for convenient city exploration.
"Meu problema foi só a garagem, o apartamento é ótimo, limpeza estava impecável."
Brazil
Jose rodrigo kallas
The price is ฿1,699
฿1,699 total
4 Jan - 5 Jan 2026
Agustín 1 Apart
Courtyard
Maran Suites & Towers - Hotel & Spa

Maran Suites & Towers - Hotel & Spa

Maran Suites & Towers - Hotel & Spa
3.5 star property
Parana
9.2 out of 10, Wonderful, (31)
Set in Parana near Urquiza Park, this hotel offers a full-service spa featuring massages, aromatherapy, and reflexology. Guests enjoy the on-site fitness centre, bar, and café, plus free breakfast and WiFi for added convenience.
"Great location and friendly, accommodating staff. "
United States
Michael
The price is ฿3,249
฿3,249 total
3 Jan - 4 Jan 2026
Maran Suites & Towers - Hotel & Spa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Santa Fe attractions

Church and Convent of San Francisco

4.3/5 (3 reviews)
Church and Convent of San Francisco is just one of the places to see in Santa Fe, so why not enjoy the other things to explore during your travels? Discover the area's museums and monuments.
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Brigadier General Estanislao Lopez Stadium

5.0/5 (1 review)
Catch an event at Brigadier General Estanislao Lopez Stadium during your trip to Santa Fe. Discover the area's live music and monuments.
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Learn more about Santa Fe

Discover colonial architecture and vibrant history at Plaza 25 de Mayo, where the Metropolitan Cathedral stands as a stunning centrepiece. Kayak along the Paraná River or visit the riverside Parque del Sur for sunset views across the water.

See all hotels in Santa Fe
Adobe

Top Santa Fe Hotel Reviews

More cheap stays in Santa Fe

Hostal Santa Fe de la Veracruz

Hostal Santa Fe de la Veracruz

San Martin 2954 Santa Fe Santa Fe
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Frequently asked questions

What's the best place to stay in Santa Fe?
Los Silos Hotel is a favourite with Expedia customers. This hotel offers a full-service spa and a casino. Other top choices based on reviews include InterTower Hotel and Hotel Puerto Amarras. See all available top hotels, or vacation rentals in Santa Fe.
If I need to cancel my hotel reservation in Santa Fe, will I receive a refund?
Yes, most room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, it may still be possible to cancel it and be given a refund within 24 hours of booking. Filter your search by fully refundable to find flexible hotel deals in Santa Fe.
What's the best accommodation for a budget-friendly stay in Santa Fe?
Based on our traveller reviews, Hostal Santa Fe de la Veracruz is a top choice for a less expensive stay. View all budget hotels in Santa Fe.
What's the best family accommodation in Santa Fe?
InterTower Hotel is a hotel with an outdoor pool and a restaurant, and it's a top choice on Expedia for families. Also, children of all ages will enjoy a visit to Alfombra Mágica. Find more child-friendly accommodations in Santa Fe.
What's the best dog-friendly accommodation option in Santa Fe?
Los Silos Hotel is a top dog-friendly hotel, and offers a full-service spa and a casino for its human guests. Other good options for you and your pet's trip include Hostel Hostal Caballito Blanco and Hostal Santa Fe de la Veracruz. See more pet-friendly hotel accommodations in Santa Fe.
What are some accommodation options with pools in Santa Fe?
InterTower Hotel: Features a full-service spa, an outdoor pool and a sauna. Los Silos Hotel and Hotel Puerto Amarras are two additional hotels that feature an on-site pool. View all hotels with pools in Santa Fe.
What is the best spa hotel in Santa Fe?
InterTower Hotel is a top spa hotel featuring a rooftop terrace, a fitness centre, a bar and an outdoor pool. Spend an afternoon at Ozio where you'll find facials, body scrubs, and detox wraps and more. Other popular spa hotels in Santa Fe include Los Silos Hotel and Hotel Los Silos. See all spa hotels in Santa Fe.
What's it like to stay in Santa Fe?
Visitors can enjoy all that Santa Fe has to offer, including the live music, university setting and festivals. Tourists can also enjoy the city's entertainment choices and parks. In Santa Fe, there are 34 hotels and other accommodation options to choose from. Find out more about Santa Fe.
What are the top places to visit in Santa Fe?
Cultural venues include Historical Provincial Museum, Centro Cultural Provincial and Museo Etnográfico y Colonial Provincial. Landmarks like Cervecería Santa Fe, Plaza 25 de Mayo and Catedral Metropolitana might be worth a visit. The picturesque setting of Botanical Garden Ing. Lorenzo Parodi and Parque Juan de Garay exemplify the area's natural beauty. Take a look at what more there is to see and do in Expedia's Santa Fe guide.
What's the weather like in Santa Fe?
The hottest months are usually January and December, with an average temperature of 25°C, while the coldest months are July and June, with an average of 14°C. Average annual precipitation for Santa Fe is 1247 mm.