What's it like in Uptown?

Guests are sure to enjoy their time checking out all that San Antonio's Uptown neighbourhood has to offer. Looking for sights you might find in a travel guide about Uptown? Consider a visit to San Antonio Zoo and Aquarium while you're in the neighbourhood.

What's the best accommodation in Uptown?

Based on Expedia customer reviews, Heritage Inn & Suites San Antonio Airport, Trademark Wyndham is the highest ranked property in Uptown. This hotel offers free breakfast and an outdoor pool. Other top choices in the neighbourhood include Drury Plaza Hotel San Antonio Airport and Wyndham Garden San Antonio Airport .

How many hotels will I be able to find in the Uptown area?

Expedia has 385 hotels and other accommodation options in Uptown to choose from, making this an ideal home base for exploring the greater San Antonio area.

If I need to cancel my hotel reservation in Uptown, will I receive a refund?

Yes, the majority of room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of the scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of booking. Enter dates in and click on "Search", then filter by "fully refundable" to view the top deals on offer in Uptown.

What can I see and do in this San Antonio neighbourhood?

Uptown's sights and attractions like Toilet Seat Museum, Marion Koogler McNay Art Museum and Parchman Stremmel Galleries offer insight into the local culture. You could also plan a visit to San Antonio Zoo and Aquarium or Alamo Quarry Market while you're in the neighbourhood. A few places to visit in the area around Uptown include Harry B Orem Stadium, Quarry Golf Club and Regal Alamo Quarry. McDermott Center and UIW Tennis Center are also worth a visit when you're out sightseeing in San Antonio.

The Best Hotels in Uptown, San Antonio - 2026 Updated Prices

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Our top choices for Uptown hotels

Drury Plaza Hotel San Antonio Airport

Uptown

Manolo

฿3,362 total

includes taxes & fees

22 Mar - 23 Mar

Best Western Garden Inn

Uptown

Robyn

฿2,361 total

includes taxes & fees

16 Mar - 17 Mar

Embassy Suites by Hilton San Antonio Airport

Uptown

Randy

฿5,149 total

includes taxes & fees

8 Apr - 9 Apr

Wyndham Garden San Antonio Airport

Uptown

Carla

฿3,310 total

includes taxes & fees

22 Mar - 23 Mar

Holiday Inn Express San Antonio-Airport by IHG

Uptown

Eduardo

฿4,446 total

includes taxes & fees

15 Mar - 16 Mar

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Uptown

Dolores

฿2,989 total

includes taxes & fees

22 Mar - 23 Mar

Courtyard by Marriott San Antonio Airport

Uptown

Brett

฿3,886 total

includes taxes & fees

22 Mar - 23 Mar

Hilton Garden Inn San Antonio Airport South

Uptown

Amy

฿3,195 total

includes taxes & fees

22 Mar - 23 Mar

Spark by Hilton San Antonio Airport

Uptown

Justin

฿2,591 total

includes taxes & fees

6 Apr - 7 Apr

Premium bedding, down duvets, in-room safe, desk

Marriott San Antonio Airport

Uptown

Kassie

฿4,932 total

includes taxes & fees

27 Mar - 28 Mar

Days Inn by Wyndham San Antonio Airport

Uptown

Daniel

฿2,362 total

includes taxes & fees

22 Mar - 23 Mar

Hampton Inn & Suites San Antonio-Airport

Uptown

Mario

฿3,414 total

includes taxes & fees

22 Mar - 23 Mar

Hilton Garden Inn San Antonio Airport

Uptown

son

฿2,083 total

includes taxes & fees

31 Mar - 1 Apr

La Quinta Inn & Suites by Wyndham San Antonio Airport

Uptown

Kirtan

฿2,780 total

includes taxes & fees

29 Mar - 30 Mar

Crowne Plaza San Antonio Airport by IHG

Uptown

Jose

฿2,802 total

includes taxes & fees

22 Mar - 23 Mar

Super 8 by Wyndham San Antonio Airport North

Uptown

Rebecca

฿2,362 total

includes taxes & fees

12 Mar - 13 Mar

SpringHill Suites by Marriott San Antonio Airport

Uptown

Leticia

฿3,512 total

includes taxes & fees

15 Mar - 16 Mar

Comfort Suites San Antonio North - Stone Oak

Uptown

Sara

฿3,105 total

includes taxes & fees

16 Mar - 17 Mar

Estancia del Norte San Antonio, Tapestry Collection by Hilton

Uptown

Meghan

฿4,827 total

includes taxes & fees

22 Mar - 23 Mar

Homewood Suites by Hilton San Antonio Airport

Uptown

April

฿3,897 total

includes taxes & fees

3 Apr - 4 Apr

View all properties

Where to stay in Uptown

Find the best Uptown areas for the activities you enjoy most.

Downtown - Riverwalk showing a river or creek, a bridge and boating

Downtown San Antonio

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

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Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

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Medical Center District

While visiting Medical Center District, you might make a stop by sights like USAA Corporate Office Headquarters and Cinemark San Antonio 16.

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Famous American landmark - Alamo mission in downtown San Antonio, Texas, USA

Stone Oak

Stone Oak is known for its abundant dining options, and you can plan a trip to Shops at Hardy Oak and Alta Vista while you're in town.

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The Alamo, San Antonio, USA © Arena Photo UK

Arena District

If you're spending some time in Arena District, Frost Bank Center and Freeman Coliseum are top sights worth seeing.

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Top Uptown Hotel Reviews

Sonesta ES Suites San Antonio Downtown Alamo Plaza

4/10 Poor

"For some reason, they did not do housekeeping in their rooms, unless you request it. So I requested it and the only towels and they said that since I have only been there for three nights at that point, it was only a light housekeeping service.. to me this is unacceptable…. I also have changed from my original because the bed was not in good conditions"