Upstate South Carolina Packages (Flight + Hotel)
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Where to stay in Upstate South Carolina
Find the best Upstate South Carolina areas and neighborhoods for the activities you enjoy most. Learn more about Upstate South Carolina
Greenville Downtown
2 out of top 10 points of interest in this area
The ample dining options and beautiful river views are top of the list for many visitors to Greenville Downtown. A stop by The Peace Center or Bon Secours Wellness Arena might round out your trip.
Nicholtown
If you're spending some time in Nicholtown, Swamp Rabbit Trail and Pleasantburg Shopping Center are top sights worth seeing.
West End
Visitors to West End like its restaurants and waterfalls, and Bi Lo Center is a sight worth a stop.
Overbrook Historic District
While Overbrook Historic District may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Beattie House and Bon Secours Wellness Arena.
Hampton-Pinckney Historic District
Hampton-Pinckney Historic District is well liked for its historical sites. If you'd like to do some sightseeing in the greater Greenville area, you might plan a trip to The Children’s Museum of the Upstate or The Peace Center.
Top hotels in Upstate South Carolina
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
851 Congaree Rd Greenville SC
Fully refundableReserve now, pay when you stay
฿2,714
฿3,075 total
13 Sept - 14 Sept
includes taxes & fees
8.6/10 Excellent! (1,005 reviews)
"The in-wall air conditioner was the loudest one I have ever heard. Horrible! The pillow, the same. Though the bed was comfy. I would suggest a grab bar for the tub/shower. Even with non-slip decals, it was slippery. TV was good. Staff needs to either supply guests with flip flops for their trips ..."
Reviewed on 6 Sept 2026
Hilton Greenville
45 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
฿3,752
฿4,251 total
13 Sept - 14 Sept
includes taxes & fees
8.4/10 Very good! (1,010 reviews)
"This has to be one of the best hotels in Greenville, if not the best. I have stayed at many hotels, both in Greenville and in cities across America, and the staff at the Hilton Greenville truly gets it. They are knowledgeable, helpful and clearly committed to providing an exceptional experience. ..."
Reviewed on 5 Sept 2026
Embassy Suites Greenville Golf Resort & Conference Center
670 Verdae Blvd Greenville SC
Fully refundableReserve now, pay when you stay
฿3,374
฿3,823 total
13 Sept - 14 Sept
includes taxes & fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Upstate South Carolina attractions
Clemson University
9.6/10 (1,439 reviews)
Take a campus tour or just explore the area of Clemson University during your travels in Clemson. Experience the area's theatre scene or attend a football match.
Falls Park on the Reedy
9.6/10 (2,661 reviews)
Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the acclaimed theatre scene or attend a sporting event in this family-friendly area.
Bon Secours Wellness Arena
8.6/10 (1,219 reviews)
Catch an event at Bon Secours Wellness Arena during your trip to Greenville. Stroll along the riverfront or experience the great live music in this family-friendly area.
Greenville Convention Center
8.4/10 (571 reviews)
Learn about the events happening in Greenville Convention Center during your trip to Greenville. Attend a sporting event or visit the shops in this family-friendly area.
Memorial Stadium
9.6/10 (410 reviews)
Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theatre scene or attend a football match.
BMW Performance Center
9.0/10 (90 reviews)
You can spend an afternoon exploring the galleries in BMW Performance Center in Greer. While in this family-friendly area, you can savour the cosy cafes.
Haywood Mall
8.8/10 (1,681 reviews)
During your trip to Greenville, you can find the perfect gifts to bring home at Haywood Mall. Experience the great live music or attend a sporting event in this family-friendly area.
What to do in Upstate South Carolina
Frequently asked questions
How much does a Upstate South Carolina holiday package cost?
Our Upstate South Carolina holiday packages, which begin from just , are an awesome way to save loads of cash. Choose your preferred flights, hotels and rental cars to create your dream getaway.
How do I get a cheap travel package to Upstate South Carolina?
You'll save piles of cash if you bundle your hotels, flights and car rentals into a Upstate South Carolina holiday package. Sometimes cheap packages mean fewer options. But that's not the case with Expedia. We offer more than 550 partner airlines and 1,000,000 hotels across the world, so you'll always have plenty of options to choose from. Eager to save even more? Add some fun activities to your package deal to unlock even bigger bargains! After all, travel is about more than simply getting to your destination.
Where should I stay in Upstate South Carolina?
Falls Park on the Reedy is one of the main things that attracts visitors to Upstate South Carolina, so it makes perfect sense that many choose to book their hotel in Greenville.
What are the top hotels in Upstate South Carolina?
Best Western Plus Greenville I-385 Inn & Suites and Comfort Inn Greenville - Haywood Mall know how to make their guests feel at home in Greenville. If you also plan to explore Seneca, take a look at Quality Inn Seneca US-123 and Tru by Hilton Seneca Clemson. Both are very popular with travellers.
How far in advance should I book my Upstate South Carolina holiday?
It can be hard to know exactly when the best time is to book your Upstate South Carolina holiday. But typically the earlier you book, the more affordable the prices. Sometimes, you can lock in your flights and hotels up to 12 months prior to departure. If you're considering a last-minute getaway, no need to fret! There are plenty of fantastic bargains announced on Expedia every single day.
What does an Expedia Upstate South Carolina travel package include?
That depends on what sort of trip you have in mind. Upstate South Carolina holiday deals can include car rentals, flights and hotels. You can mix and match to find the travel package that suits your budget and style. You can also add on activities and experiences after you've booked to score even bigger discounts.
What should I know before booking a Upstate South Carolina travel package?
An Expedia travel package can be customized for your budget and is a fantastic way to make your budget go further. What you include is totally up to you. Rental cars, hotels and flights — decide on a combination that suits your style.
Can I choose my airline with a Upstate South Carolina Expedia holiday package?
Yes, of course. Expedia has access to more than 550 airline partners globally, so go with the carrier that best fits your budget and travel needs.
If I'm not able to travel, can I cancel my Upstate South Carolina holiday package?
If your travel plans in Upstate South Carolina have been upended, it's comforting to know that you can cancel your booking. If you made your booking in the last 24 hours, you may be eligible for a refund. If your booking was made more than 24 hours ago, your airline, hotel or car rental company may impose fees. To learn more, check our Customer Service Portal.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
