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Find hotels in Upstate South Carolina, SC from ฿2,380

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14 Sep - 15 Sep
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15 Sep - 16 Sep
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18 Sep - 20 Sep
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25 Sep - 27 Sep

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Our top choices for Upstate South Carolina hotels

1. Tru by Hilton Spartanburg

Tru by Hilton Spartanburg
Spartanburg
United States
Jeremy
฿3,513
฿3,899 total
includes taxes & fees
4 Oct - 5 Oct
Tru by Hilton Spartanburg

2. Four Points by Sheraton Spartanburg

Four Points by Sheraton Spartanburg
Spartanburg
United States
Travis
฿3,540
฿3,929 total
includes taxes & fees
27 Sept - 28 Sept
Four Points by Sheraton Spartanburg

3. Hilton Garden Inn Spartanburg

Hilton Garden Inn Spartanburg
Spartanburg
United States
Stan
฿4,303
฿4,776 total
includes taxes & fees
4 Oct - 5 Oct
Hilton Garden Inn Spartanburg

4. Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
Spartanburg
United States
Michael
฿3,391
฿3,764 total
includes taxes & fees
20 Sept - 21 Sept
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

5. AC Hotel by Marriott Spartanburg

AC Hotel by Marriott Spartanburg
Spartanburg
United States
Willow
฿5,255
฿5,833 total
includes taxes & fees
27 Sept - 28 Sept
AC Hotel by Marriott Spartanburg

6. Best Western Spartanburg I-26

Best Western Spartanburg I-26
Spartanburg
United States
Jonathan
฿3,062
฿3,399 total
includes taxes & fees
22 Sept - 23 Sept
Best Western Spartanburg I-26

7. Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

Hampton Inn & Suites Spartanburg-I-26-Westgate Mall
Spartanburg
Canada
MARLON
฿3,903
฿4,332 total
includes taxes & fees
4 Oct - 5 Oct
Hampton Inn & Suites Spartanburg-I-26-Westgate Mall

8. Fairfield Inn & Suites by Marriott Greenville Spartanburg/Duncan

Fairfield Inn & Suites by Marriott Greenville Spartanburg/Duncan
Duncan
United States
Christine
฿4,364
฿4,910 total
includes taxes & fees
21 Sept - 22 Sept
Fairfield Inn & Suites by Marriott Greenville Spartanburg/Duncan

9. Comfort Suites At WestGate Mall

Comfort Suites At WestGate Mall
Spartanburg
United States
Savannah
฿3,029
฿3,362 total
includes taxes & fees
11 Oct - 12 Oct
Comfort Suites At WestGate Mall

10. Hampton Inn & Suites Greenville Airport, SC

Hampton Inn & Suites Greenville Airport, SC
Greenville
United States
Kristina
฿3,461
฿3,921 total
includes taxes & fees
27 Sept - 28 Sept
Hampton Inn & Suites Greenville Airport, SC

11. Comfort Suites Greenville Airport

Comfort Suites Greenville Airport
Greenville
United States
Ryan
฿3,076
฿3,485 total
includes taxes & fees
4 Oct - 5 Oct
Comfort Suites Greenville Airport

12. Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center
Greenville
United States
Pedro
฿3,388
฿3,838 total
includes taxes & fees
27 Sept - 28 Sept
Embassy Suites Greenville Golf Resort & Conference Center

13. Spartanburg Marriott

Spartanburg Marriott
Spartanburg
Canada
Sarah
฿3,919
฿4,481 total
includes taxes & fees
4 Oct - 5 Oct
Spartanburg Marriott

14. Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG
Spartanburg
United States
April
฿3,636
฿4,035 total
includes taxes & fees
20 Sept - 21 Sept
Holiday Inn Express I-26 & Us 29 At Westgate Mall by IHG

15. Courtyard by Marriott Greenville Mauldin

Courtyard by Marriott Greenville Mauldin
Greenville
United States
Leticia
฿3,933
฿4,326 total
includes taxes & fees
20 Sept - 21 Sept
Courtyard by Marriott Greenville Mauldin

16. Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites
Greenville
United States
Sara
฿2,524
฿2,776 total
includes taxes & fees
4 Oct - 5 Oct
Best Western Plus Greenville I-385 Inn & Suites

17. Hampton Inn & Suites Greenville/Spartanburg I-85, SC

Hampton Inn & Suites Greenville/Spartanburg I-85, SC
Duncan
United States
Kathy
฿3,171
฿3,520 total
includes taxes & fees
5 Oct - 6 Oct
Hampton Inn & Suites Greenville/Spartanburg I-85, SC

18. Hotel Hartness

Hotel Hartness
Greenville
United States
Cornelius
฿5,030
฿6,789 total
includes taxes & fees
4 Oct - 5 Oct
Hotel Hartness

19. Best Western Spartanburg Northwest

Best Western Spartanburg Northwest
Spartanburg
United States
Darius
฿3,062
฿3,467 total
includes taxes & fees
20 Sept - 21 Sept
Best Western Spartanburg Northwest

20. Drury Inn & Suites Greenville

Drury Inn & Suites Greenville
Greenville
United States
Gohan
฿4,957
฿5,453 total
includes taxes & fees
17 Sept - 18 Sept
Drury Inn & Suites Greenville
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Holiday Rentals in Upstate South Carolina

Aparthotel

Landing Apartments - Lyman

Landing Apartments - Lyman
Lyman
"Great room that was nice and clean. Smooth check-in."
Landing Apartments - Lyman
Cabin

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Seneca
"Me and my family had a great time"
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy
Aparthotel

stayAPT Suites Greenville-Haywood Mall

stayAPT Suites Greenville-Haywood Mall
Greenville
"The rooms are spacious and feels like a and apartment. This place is one of the best places to stay."
stayAPT Suites Greenville-Haywood Mall
Cabin

Carolina Camp Cedar

Carolina Camp Cedar
Pickens
"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"
Carolina Camp Cedar
Apartment

Mint House Greenville Downtown by Kasa

Mint House Greenville Downtown by Kasa
Greenville Downtown
"The unit was very clean, and I stay here whenever I'm in Greenville."
Mint House Greenville Downtown by Kasa
Cottage

Greer Guest House < 1 Mi to Park & Downtown Area!

Greer Guest House < 1 Mi to Park & Downtown Area!
Greer
"Nice place en Greenville area "
Greer Guest House < 1 Mi to Park & Downtown Area!
Aparthotel

The Station by Compo Hotels

The Station by Compo Hotels
Travelers Rest
"Lovely place to stay. Very clean and well appointed. The host was responsive and welcoming. Comfortable bed and quiet. Highly recommend."
The Station by Compo Hotels
Cottage

Clemson Memorabilia House

Clemson Memorabilia House
Clemson
"We enjoyed our stay, it was the perfect size for our family of four. "
Clemson Memorabilia House
Mobile Home

Carolina Landing RV Resort - Caravan Park

Carolina Landing RV Resort - Caravan Park
Fair Play
"Very nice stay with friendly staff"
Carolina Landing RV Resort - Caravan Park
Cottage

Claires Cottage ~ 4 Mi to Downtown Greenville!

Claires Cottage ~ 4 Mi to Downtown Greenville!
Greenville
"Great trip. The small cottage was perfect for my wife and I and the owner was very responsive."
Claires Cottage ~ 4 Mi to Downtown Greenville!
Cottage

1 Mi to Downtown Greer: Family Home w/ Gazebo!

1 Mi to Downtown Greer: Family Home w/ Gazebo!
Greer
"Very cute home close to everything. Super clean and spacious. Well furnished."
1 Mi to Downtown Greer: Family Home w/ Gazebo!
Cottage

2 Mi to Downtown: Luxe Greenville Retreat!

2 Mi to Downtown: Luxe Greenville Retreat!
Greenville
"Great house! Very clean and comfortable. Outstanding amenities. Conveniently located. "
2 Mi to Downtown: Luxe Greenville Retreat!
Cottage

Families Welcome, Fenced Yard: Inviting Greer Home

Families Welcome, Fenced Yard: Inviting Greer Home
Greer
"This property is such an amazing find. Three large bedrooms, very clean and well maintained. Close to town of Greer and all amenities. Very easy check-in. Beds very comfortable. Kitchen well equipped for the week we were there."
Families Welcome, Fenced Yard: Inviting Greer Home
Cottage

Lake Access & Boat Slip: Greenwood Cottage!

Lake Access & Boat Slip: Greenwood Cottage!
Greenwood
"Outstanding little cottage for my mom and daughter weekend! Super clean and comfortable. "
Lake Access & Boat Slip: Greenwood Cottage!
Cottage

4 Seasons of Fun! Walhalla Home w/ Spacious Yard!

4 Seasons of Fun! Walhalla Home w/ Spacious Yard!
Walhalla
"The house was perfect for our group for our golf trip. We had one minor issue and we were able to speak to the host and they had someone to correct it quickly so that it didn’t disrupt our trip in any way. Place was clean, peaceful, with great hosts."
4 Seasons of Fun! Walhalla Home w/ Spacious Yard!
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Stay near popular Upstate South Carolina attractions

A historic building with a clock tower, surrounded by a well-maintained lawn with a paw print design.

Clemson University

9.6/10 (1,439 reviews)
Enjoy the student vibe around Clemson University, a top university in Clemson. Experience the area's theatre scene or attend a football match.
See properties
A pedestrian bridge with colorful lights, surrounded by trees and a distant building.

Falls Park on the Reedy

9.6/10 (2,661 reviews)
Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the acclaimed theatre scene or attend a sporting event in this family-friendly area.
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Bon Secours Wellness Arena

8.6/10 (1,219 reviews)
Catch an event at Bon Secours Wellness Arena during your trip to Greenville. Stroll along the riverfront or experience the great live music in this family-friendly area.
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Greenville Convention Center

8.4/10 (571 reviews)
Learn about the events happening in Greenville Convention Center during your trip to Greenville. Attend a sporting event or visit the shops in this family-friendly area.
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Memorial Stadium

9.6/10 (410 reviews)
Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theatre scene or attend a football match.
See properties

BMW Performance Center

9.0/10 (90 reviews)
You can spend an afternoon exploring the galleries in BMW Performance Center in Greer. While in this family-friendly area, you can savour the cosy cafes.
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Haywood Mall

8.8/10 (1,681 reviews)
During your trip to Greenville, you can find the perfect gifts to bring home at Haywood Mall. Experience the great live music or attend a sporting event in this family-friendly area.
See properties

Learn more about Upstate South Carolina

Check out the local area in Upstate South Carolina—home to attractions like Heritage Park and CCNB Amphitheatre.

See all hotels in Upstate South Carolina
A multi-tiered waterfall cascading over rocks in a forested area.
Photo by Ryan Watts

Top Upstate South Carolina Hotel Reviews

Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

8/10 Good
"Great location & friendly staff. Room was clean. The hotel is a tad dated and worn , no doubt b/c it’s a popular place to stay but overall very pleasant"
Anne 2-night trip
Posted 7 hours ago
Best Western Plus Clemson Hotel & Conference Center
Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

10/10 Excellent
"Room was clean, staff was very nice"
Brittany 2-night trip
Posted 9 hours ago
Embassy Suites Greenville Golf Resort & Conference Center
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

10/10 Excellent
"Always Stay Here When I'm In Clemson! Great Rates Great Staff!!"
Bradley 2-night trip
Posted 12 hours ago
Comfort Inn & Suites Clemson - University Area
Best Western Spartanburg I-26

Best Western Spartanburg I-26

10/10 Excellent
"Clean rooms, quiet, good breakfast"
Catherine 1-night trip
Posted 13 hours ago
Best Western Spartanburg I-26
Hotel Hartness

Hotel Hartness

10/10 Excellent
"Wish we could have stayed longer, will definitely return!"
Judith 1-night trip
Posted 1 day ago
Hotel Hartness
Inn @ Clemson

Inn @ Clemson

8/10 Good
"Super friendly staff! Only complaint was the mattress and the pillows. They certainly need an upgrade!"
Tonya Lynn 1-night trip
Posted 1 day ago
Inn @ Clemson
La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.

10/10 Excellent
"Customer service was great! There was an issue on their end with my deposit but it was quickly resolved. The rooms were clean and I saw housekeeping cleaning other rooms. They did serve continental breakfast but I did not partake so I can not speak on it but lots of people seemed to enjoy. I felt very safe as a solo traveler. Amazing property for the price I paid!"
Kierra 3-night trip
Posted 2 days ago
La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd.
Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

8/10 Good
"Room was not ready. Check in said 4:00 but we had to wait a long time and they couldn’t tell us when our room would be ready."
Sandra 1-night trip
Posted 2 days ago
Grand Bohemian Lodge Greenville, Autograph Collection
Mint House Greenville Downtown by Kasa

Mint House Greenville Downtown by Kasa

10/10 Excellent
"Parking was the only real issue I had because I arrived before I got the check-in email. Had I waited, i less if you’re gonna be playingt was perfectly clear what I needed to do. It was located in a very convenient place close to Falls Park. It was a spacious unit and everything was clean. Very pleased."
Dayton 1-night trip
Posted 2 days ago
Mint House Greenville Downtown by Kasa

More cheap stays in Upstate South Carolina

WoodSpring Suites Spartanburg - Duncan

WoodSpring Suites Spartanburg - Duncan

255 Frontage Rd. Duncan SC
฿2,115
฿2,380 total
16 Sept - 17 Sept
includes taxes & fees
WoodSpring Suites Spartanburg - Duncan
Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites

831 Congaree Rd Greenville SC
฿2,524
฿2,776 total
4 Oct - 5 Oct
includes taxes & fees
Best Western Plus Greenville I-385 Inn & Suites
Comfort Inn Greenville - Haywood Mall

Comfort Inn Greenville - Haywood Mall

246 Congaree Road Greenville SC
฿2,709
฿3,079 total
4 Oct - 5 Oct
includes taxes & fees
Comfort Inn Greenville - Haywood Mall
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

1310 Tiger Blvd Clemson SC
฿3,343
฿3,711 total
16 Sept - 17 Sept
includes taxes & fees
8/10 Very good! (1,011 reviews)
Best Western Plus Clemson Hotel & Conference Center
Comfort Inn & Suites Clemson - University Area

Comfort Inn & Suites Clemson - University Area

1305 Tiger Blvd Clemson SC
฿3,483
฿3,867 total
8 Oct - 9 Oct
includes taxes & fees
8.4/10 Very good! (1,005 reviews)
Comfort Inn & Suites Clemson - University Area
Lakeside Lodge Clemson

Lakeside Lodge Clemson

13500 Clemson Blvd Seneca SC
฿3,602
฿4,472 total
16 Sept - 17 Sept
includes taxes & fees
Lakeside Lodge Clemson

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