A space shuttle exhibit with a large model of a space shuttle, a red pillar, and informational displays.

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Check prices for these dates

This weekend
30 Oct - 1 Nov
Next weekend
6 Nov - 8 Nov

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Our top choices for St. Louis Science Center hotels

An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.

1. Hampton Inn & Suites St. Louis at Forest Park

Hampton Inn & Suites St. Louis at Forest Park
3.5 star property
Dogtown, 1 km from St. Louis Science Center
9.4 out of 10, Exceptional, (1,003 reviews)
"Well maintained, great staff and very clean."
United States
Greg
The price is ฿4,399
฿5,188 total
includes taxes & fees
15 Nov - 16 Nov
Hampton Inn & Suites St. Louis at Forest Park
Lobby

2. Drury Inn & Suites St. Louis Forest Park

Drury Inn & Suites St. Louis Forest Park
3.0 star property
2 km from St. Louis Science Center
9.4 out of 10, Exceptional, (1,029 reviews)
"Loved staying there!"
United States
Tammy
The price is ฿4,555
฿5,326 total
includes taxes & fees
9 Nov - 10 Nov
Drury Inn & Suites St. Louis Forest Park
A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.

3. The Royal Sonesta Chase Park Plaza St. Louis

The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
Central West End, 1.8 km from St. Louis Science Center
9.2 out of 10, Wonderful, (1,001 reviews)
"The hotel is beautiful, and we really enjoyed the restaurants--The Tenderloin Room was especially delicious!"
United States
Sara
The price is ฿4,521
฿6,326 total
includes taxes & fees
22 Nov - 23 Nov
The Royal Sonesta Chase Park Plaza St. Louis
A modern living room with a fireplace, sofas, a coffee table, and a bookshelf.

4. AC Hotel St. Louis Central West End

AC Hotel St. Louis Central West End
4.0 star property
Central West End, 1.8 km from St. Louis Science Center
9.0 out of 10, Wonderful, (860 reviews)
"Everything at this hotel was perfect. From the valet to the front desk to the breakfast were so friendly and nice. We will definitely stay here again. The location is also perfect"
United States
Janice
The price is ฿4,847
฿5,716 total
includes taxes & fees
8 Nov - 9 Nov
AC Hotel St. Louis Central West End
An outdoor patio area with seating, planters, and a grill.

5. Element by Marriott St. Louis Midtown

Element by Marriott St. Louis Midtown
3.0 star property
Midtown, 2.7 km from St. Louis Science Center
8.8 out of 10, Excellent, (852 reviews)
"Would stay again!"
United States
Julie
The price is ฿4,825
฿5,642 total
includes taxes & fees
15 Nov - 16 Nov
Element by Marriott St. Louis Midtown
An outdoor patio area with tables and chairs, string lights, and umbrellas.

6. Hotel Indigo St Louis - Central West End by IHG

Hotel Indigo St Louis - Central West End by IHG
3.5 star property
Central West End, 1.7 km from St. Louis Science Center
8.8 out of 10, Excellent, (1,002 reviews)
"Very clean and nicely furnished rooms. Lobby was slightly underwhelming but overall we had a very comfortable stay!"
United States
Bobak
The price is ฿4,218
฿5,344 total
includes taxes & fees
22 Nov - 23 Nov
Hotel Indigo St Louis - Central West End by IHG
A hot tub with a wooden deck, surrounded by a bamboo fence, and string lights.

7. The West End

The West End
2.0 star property
Central West End, 2.3 km from St. Louis Science Center
8.6 out of 10, Excellent, (704 reviews)
"Excellent value, location. I'd stay here again."
United States
Trevor
The price is ฿2,363
฿3,438 total
includes taxes & fees
1 Nov - 2 Nov
The West End
An outdoor seating area with a fire pit, cushioned benches, and a covered patio with string lights.

8. Home2 Suites by Hilton St. Louis/Forest Park

Home2 Suites by Hilton St. Louis/Forest Park
3.0 star property
The Grove, 0.9 km from St. Louis Science Center
8.6 out of 10, Excellent, (1,002 reviews)
"Very helpful staff, free parking, breakfast included. Great location for the zoo or city museum."
United States
Molly
The price is ฿5,246
฿6,134 total
includes taxes & fees
15 Nov - 16 Nov
Home2 Suites by Hilton St. Louis/Forest Park
An outdoor dining area with a glass table and chairs, a neon sign, and a city view.

9. Aloft by Marriott St Louis Central West End

Aloft by Marriott St Louis Central West End
3.0 star property
Central West End, 1.8 km from St. Louis Science Center
8.6 out of 10, Excellent, (1,000 reviews)
"Very nice staff and helped us with all our needs and was close to the event we were going to and loved the pool table and pool they had there"
United States
Brittany
The price is ฿3,843
฿4,494 total
includes taxes & fees
2 Nov - 3 Nov
Aloft by Marriott St Louis Central West End
A modern hotel room with a large bed, a desk with a chair, a blue armchair, a sofa, a TV, and a large window offering a city view.

10. DoubleTree by Hilton St. Louis Forest Park

DoubleTree by Hilton St. Louis Forest Park
4.0 star property
Central West End, 1.3 km from St. Louis Science Center
8.4 out of 10, Very good, (1,005 reviews)
"All was good"
United States
Loleta
The price is ฿5,018
฿5,917 total
includes taxes & fees
8 Nov - 9 Nov
DoubleTree by Hilton St. Louis Forest Park
A spacious foyer with a grand staircase, a piano, and a large rug.

11. White House at Grand Central

White House at Grand Central
3.5 star property
3 km from St. Louis Science Center
8.4 out of 10, Very good, (167 reviews)
"Very spacious clean old house apartments"
United States
Priscilla
The price is ฿2,566
฿4,180 total
includes taxes & fees
9 Nov - 10 Nov
White House at Grand Central
A bedroom with a large bed, a mirror, and a vanity with shelves.

12. Central West End B&B

Central West End B&B
3.5 star property
Central West End, 3 km from St. Louis Science Center
8.0 out of 10, Very good, (57 reviews)
"Really enjoyed the comfort. I would recommend this place to anyone. Very nice breakfast also!!! "
United States
Stacee
The price is ฿5,555
฿6,988 total
includes taxes & fees
2 Nov - 3 Nov
Central West End B&B
A hotel room with two beds, a chair, a desk, and a large window.

13. Forest Park Hotel by MDR

Forest Park Hotel by MDR
3.0 star property
The Hill, 1.8 km from St. Louis Science Center
7.4 out of 10, Good, (1,683 reviews)
"The rooms were spacious and beds so comfortable."
United States
Kevan
The price is ฿2,448
฿3,019 total
includes taxes & fees
29 Nov - 30 Nov
Forest Park Hotel by MDR
A hotel room with a large bed, a desk, a chair, a television, and a microwave.

14. Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave 

Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave 
2.5 star property
The Hill, 1.8 km from St. Louis Science Center
6.0 out of 10, (1,001 reviews)
"Okay for a one night stay."
United States
Sean
The price is ฿2,532
฿2,960 total
includes taxes & fees
2 Nov - 3 Nov
Red Roof Inn PLUS+ St Louis - Forest Park/ Hampton Ave 
A well-lit lobby with a chandelier, potted plants, and a seating area.

15. Truitt Hotel

Truitt Hotel
2.0 star property
Lafayette Square, 4.9 km from St. Louis Science Center
10.0 out of 10, Exceptional, (24 reviews)
"Amazing stay, gorgeous rooms and buildings, perfect getaway"
United States
Gabrielle
The price is ฿5,668
฿6,881 total
includes taxes & fees
1 Nov - 2 Nov
Truitt Hotel
A rooftop terrace with rows of metal chairs and a view of city buildings.

16. Drury Plaza Hotel St. Louis at the Arch

Drury Plaza Hotel St. Louis at the Arch
3.0 star property
Downtown St. Louis, 7.1 km from St. Louis Science Center
9.6 out of 10, Exceptional, (3,811 reviews)
"Staff was super nice and helpful. Breakfast was great and happy hour was a pleasant surprise"
United States
Blake
The price is ฿4,855
฿5,677 total
includes taxes & fees
10 Nov - 11 Nov
Drury Plaza Hotel St. Louis at the Arch
An indoor swimming pool with clear glass walls, a tiled floor, and a 'Step Down' sign.

17. Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
4.0 star property
6.5 km from St. Louis Science Center
9.6 out of 10, Exceptional, (1,000 reviews)
"Really enjoyed the breakfast and happy hours!"
United States
Stacey Rochelle
The price is ฿4,318
฿5,129 total
includes taxes & fees
22 Nov - 23 Nov
Drury Plaza Hotel St. Louis Brentwood
A spacious lobby with modern seating, a reception desk, and large windows offering views of the parking area.

18. Pear Tree Inn St. Louis Airport

Pear Tree Inn St. Louis Airport
2.5 star property
15 km from St. Louis Science Center
9.4 out of 10, Exceptional, (3,334 reviews)
"The Staff, clean room & breakfast was great 👍"
United States
Curtiss
The price is ฿3,034
฿3,603 total
includes taxes & fees
8 Nov - 9 Nov
Pear Tree Inn St. Louis Airport
A modern outdoor lounge area with seating, a bar, and a view of a cityscape.

19. Live by Loews - St.Louis

Live by Loews - St.Louis
4.0 star property
Downtown St. Louis, 6.7 km from St. Louis Science Center
9.4 out of 10, Exceptional, (1,357 reviews)
"Great place to stay."
United States
brandon
The price is ฿4,687
฿5,574 total
includes taxes & fees
15 Nov - 16 Nov
Live by Loews - St.Louis
A modern hotel lobby with a glass facade, seating area, and a staircase.

20. Four Seasons Hotel St Louis

Four Seasons Hotel St Louis
5.0 star property
7.5 km from St. Louis Science Center
9.4 out of 10, Exceptional, (1,000 reviews)
"Exceptional, from check-in to check-out!"
United States
Nicole
The price is ฿12,645
฿14,786 total
includes taxes & fees
10 Nov - 11 Nov
Four Seasons Hotel St Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to St. Louis Science Center

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
An indoor swimming pool with lounge chairs and a pool table, surrounded by large windows.
Hampton Inn & Suites St. Louis at Forest Park
3.5 star property
9.4
Exceptional
1,003 reviews
View
Lobby
Drury Inn & Suites St. Louis Forest Park
3.0 star property
9.4
Exceptional
1,029 reviews
View
A hotel with a swimming pool, lounge chairs, and a courtyard with palm trees.
The Royal Sonesta Chase Park Plaza St. Louis
4.5 star property
9.2
Wonderful
1,001 reviews
View
A modern living room with a fireplace, sofas, a coffee table, and a bookshelf.
AC Hotel St. Louis Central West End
4.0 star property
9.0
Wonderful
860 reviews
View
An outdoor patio area with seating, planters, and a grill.
Element by Marriott St. Louis Midtown
3.0 star property
8.8
Excellent
852 reviews
View

Top St. Louis Science Center Hotel Reviews

Forest Park Hotel by MDR

Forest Park Hotel by MDR

10/10 Excellent
"Our stay was perfectly fine considering the price. I have nothing to complain about. It’s nothing fancy, but staff was very friendly and helpful, the room was clean, and the bed was soft. If I just needed a room to sleep in for the night, I would have no problem staying here again."
Isabelle 1-night trip
Posted 1 hour ago
Forest Park Hotel by MDR

Other attractions near St. Louis Science Center

A modern building with large glass windows and a garden with red and pink tulips.

Jewel Box

Made of stacked glass in a restored art deco style, this glass house from the 1930s continues to flourish with tropical trees, hanging plants and a large fountain.
See properties

Frequently asked questions

What's the area like around St. Louis Science Center?
St. Louis Science Center is located in a welcoming area of St. Louis known for its picturesque gardens and sporting events. If you're looking for a convenient place to stay, take a look at the 74 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay near St. Louis Science Center?
Hampton Inn & Suites St. Louis at Forest Park is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an indoor pool. It's located just a short 0.6 mi (1 km) from St. Louis Science Center. Other good choices within a short distance include Home2 Suites by Hilton St. Louis/Forest Park and DoubleTree by Hilton St. Louis Forest Park.
How many hotels should I expect to find close to St. Louis Science Center?
Expedia has 74 hotels and other accommodation options within a mile from St. Louis Science Center.
If I need to cancel the hotel reservation for my stay near St. Louis Science Center, will I receive a refund?
Yes, most hotel room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then you can filter by "fully refundable" to review the best deals near St. Louis Science Center.
What can I see and do near St. Louis Science Center?
Cathedral Basilica of St. Louis, St. Louis Art Museum and City Museum feature captivating exhibits. St. Louis Union Station, Jewel Box and Cherokee Street are monuments to see when you're exploring the area around St. Louis Science Center. You can check out the local talent at The Muny Theater, Fox Theater and St. Louis Symphony Orchestra.