A large white building with a dome and a statue in front, surrounded by fountains and trees.

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Check availability on St. Louis Boutique Hotels

This weekend
30 Oct - 1 Nov
Next weekend
6 Nov - 8 Nov

Our top choices for St. Louis boutique hotels

A rooftop restaurant with round tables, chairs, and a view of the city.

1. Moonrise Hotel

Moonrise Hotel
4.0 star property
Delmar Loop
9.0 out of 10, Wonderful, (2,048 reviews)
"Great location."
United States
Jennifer
The price is ฿5,026
฿5,978 total
includes taxes & fees
18 Nov - 19 Nov
Moonrise Hotel
A cozy lounge area with leather sofas, a fireplace, and a bar counter.

2. The Cheshire

The Cheshire
4.0 star property
Richmond Heights
8.8 out of 10, Excellent, (1,008 reviews)
"Fantastic hotel, clean and nice rooms, great breakfast and location"
United States
Matthew
The price is ฿5,015
฿5,954 total
includes taxes & fees
15 Nov - 16 Nov
The Cheshire
A traditional Tudor-style building with a black awning labeled "28 Sally's Inn."

3. Seven Gables, St. Louis West, a Tribute Portfolio Hotel

Seven Gables, St. Louis West, a Tribute Portfolio Hotel
3.5 star property
Clayton
8.4 out of 10, Very good, (603 reviews)
"I always stay at the Seven Gables Inn while visiting St. Louis - fantastic, walkable neighborhood, for central STL, including vintage shopping & dining options. The boutique hotel is very ‘Old St. Louis’ with extremely modern, comfortable, quiet and safe rooms."
United States
Jennifer
The price is ฿5,033
฿6,200 total
includes taxes & fees
1 Nov - 2 Nov
Seven Gables, St. Louis West, a Tribute Portfolio Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St. Louis Hotel Reviews

Frequently asked questions

What's the best boutique accommodation in St. Louis?
Moonrise Hotel is a favourite hotel with Expedia travellers looking for a stylish stay, and features 2 bars and free parking. The Cheshire and Seven Gables, St. Louis West, a Tribute Portfolio Hotel are other boutique-style choices.
What's there to see and do in St. Louis?
Visitors speak positively about this destination's art galleries, great live music and popular theatre scene. Activities and attractions to experience around St. Louis include St. Louis Union Station, Stifel Theatre and City Museum. You might also want to see places such as St. Louis Zoo, National Blues Museum and Museum at the Gateway Arch during your trip.
What kind of weather should I plan for when I travel to St. Louis?
Understanding the weather in St. Louis will help you enjoy your stay to the fullest. The hottest months are usually July and August, with an average temperature of 24°C, while the coldest months are January and February, with an average of 3°C. Average annual precipitation for St. Louis is 1374 mm.
What's the best way to get to my boutique hotel in St. Louis?
You have a few options for getting to St. Louis. The closest major airport is Lambert-St. Louis International Airport (STL), which is located 11.6 mi (18.7 km) away. You can access metro transport at Stadium Station, 8th and Pine Station and Convention Center Station.