Southeastern Indiana Packages (Flight + Hotel)

Book a Hotel + Flight or Car together to unlock savings

Photo by Serendipity Trip

  • Plan, book, travel with confidence

  • Better together

    Save up to ฿4,531 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Southeastern Indiana

Find the best Southeastern Indiana areas and neighborhoods for the activities you enjoy most. Learn more about Southeastern Indiana
Louisville Science Center which includes outdoor art

West Main Historic District

A noteworthy feature of West Main Historic District is its fantastic nightlife. While you're in town, be sure to stop and check out Frazier International History Museum and Louisville Slugger Museum.

Find hotels in West Main Historic District

Top hotels in Southeastern Indiana

Radisson Hotel Louisville North

Radisson Hotel Louisville North

3 out of 5
505 Marriott Drive Clarksville IN
Fully refundableReserve now, pay when you stay
The price is ฿1,828 per night from 16 Jan to 17 Jan
฿1,828
฿2,065 total
16 Jan - 17 Jan
includes taxes & fees
6.8/10 (2,723 reviews)
Great view

Reviewed on 11 Jan 2026

Radisson Hotel Louisville North
Hampton Inn New Albany Louisville West

Hampton Inn New Albany Louisville West

2.5 out of 5
411 W Spring Street New Albany IN
Fully refundableReserve now, pay when you stay
The price is ฿2,946 per night from 5 Feb to 6 Feb
฿2,946
฿3,329 total
5 Feb - 6 Feb
includes taxes & fees
8.8/10 Excellent! (748 reviews)
Didn’t get to get breakfast I slept straight through it. Rooms very clean staff was great

Reviewed on 1 Jan 2026

Hampton Inn New Albany Louisville West
TownePlace Suites by Marriott Louisville North

TownePlace Suites by Marriott Louisville North

3 out of 5
301 West Maple Street Jeffersonville IN
Fully refundableReserve now, pay when you stay
The price is ฿3,499 per night from 7 Feb to 8 Feb
฿3,499
฿3,954 total
7 Feb - 8 Feb
includes taxes & fees
9/10 Wonderful! (650 reviews)
I enjoyed the pool, wish the hot tub was working

Reviewed on 9 Jan 2026

TownePlace Suites by Marriott Louisville North
See all 1,166 properties in Southeastern Indiana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

KFC Yum Center

Catch an event at KFC Yum Center during your trip to Louisville. Stroll along the riverfront or attend a sporting event in the area.

KFC Yum Center

Paoli Peaks Ski Resort

Hit the slopes at Paoli Peaks Ski Resort during your trip to Paoli. While you're in the area, find time to visit its casinos.

Paoli Peaks Ski Resort

Frequently asked questions

Can I cancel my flight booking to Southeastern Indiana due to COVID-19?
If you haven't booked yet, check the terms and conditions of the airline you're considering. If you've already reserved your flight to Southeastern Indiana, head to our Customer Service Portal. The information here will help determine which COVID-19 policies apply to your booking and provide advice on the next steps.
What's the best way to find cheap flights to Southeastern Indiana that have flexible change policies?
It's as easy as 1-2-3 with Expedia. Firstly, type in your preferred dates and destination and press "Search." Next, check the "No change fee" box directly below the "Flexible change policies" subheading to the left of the screen. Step 3. Reserve a cheap and flexible airfare to Southeastern Indiana.
What are some of the general tips for travellers to Southeastern Indiana during the COVID-19 outbreak?
With strict COVID-19 precautions to adhere to, travel looks a bit different these days. Here's what you should know before you jet off to Southeastern Indiana:
  • Research if any travel restrictions apply to your origin and destination before locking in a flight. Also check if there are any conditions you'll have to follow on arrival, such as proof of a negative COVID-19 test.
  • You must wear a face mask at the airport, including at security checkpoints. You should be prepared to lower your mask for identification purposes when asked by a TSA employee.
  • To minimize the risk of cross-contamination, place your boarding pass on the reader yourself and then hold it up for inspection. Do not hand your pass directly to a TSA officer.
  • TSA now allows passengers to take one container of hand sanitizer, up to 12 oz (350 ml) in size, in carry-on bags. This will need to be removed from your bag at the X-ray machine for screening.
  • Place any personal items (e.g, keys, phone and wallet) in your carry-on instead of a bin to minimize handling during screening.
  • Transport all food items in a clear plastic bag and also place them in a screening bin. Keeping food separate from your carry-on makes it less likely that a TSA officer will need to touch and open your bag for inspection.

Which airlines fly to Southeastern Indiana?
Let American Airlines fly you there. This renowned carrier operates 13307 services per month to O'Hare Intl. Airport (ORD), a Southeastern Indiana gateway.
How can I find cheap tickets to Southeastern Indiana?
An effective strategy for picking up cheap fares is to be flexible with your travel dates. Start by searching for your flight to Southeastern Indiana, then click on the "flexible dates" link to see prices for nearby days. Another handy tip? Book well ahead. For an idea of costs, was the best price for a flight to Southeastern Indiana in the last seven days.
How much is a flight to Southeastern Indiana?
In the last seven days, round-trip airfares to Southeastern Indiana sold for as low as and reached a maximum price of . For one-way journeys departing from (), the lowest price during this time was only .
What are the most popular airports to fly into in Southeastern Indiana?
Fly into O'Hare Intl. Airport (ORD) and sample the best that Southeastern Indiana has to offer. As the region's main point of entry, roughly 33491 flights land here every month.
When is the cheapest time to fly to Southeastern Indiana?
Leave for Southeastern Indiana earlier in the week and you'll usually be rewarded with more affordable fares. Tuesday is generally the cheapest day to jump on a plane, followed closely by Monday. If you'd like to avoid the priciest flights, steer clear of Saturdays.
How much is a plane ticket to Southeastern Indiana?
In the last seven days, airfares ranged between and . Scroll through our sensational deals to Southeastern Indiana, pick your favourite and then get ready for your getaway!
Which airlines with flights to Southeastern Indiana employ COVID-19 cleanliness policies?
While flying in the middle of a pandemic can be nerve-wracking, airlines have been working hard to ensure the well-being of all on board. Here are a few carriers that have implemented changes:
  • United Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.
  • American Airlines - this airline is known for providing passenger masks and cleaning with disinfectant.
  • Delta - this airline is known for electrostatic cleaning and cleaning with disinfectant.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.