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13 Nov - 15 Nov
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20 Nov - 22 Nov

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Our top choices for South Central Houston hotels

A modern building with a sign reading 'INTERCONTINENTAL' and 'SAFINA MEDITERRANEAN'.

1. InterContinental Houston by IHG

InterContinental Houston by IHG
4.0 star property
South Central Houston
9.4 out of 10, Exceptional, (1,007 reviews)
"Great stay!"
United States
Luke
The price is ฿5,102
฿6,641 total
includes taxes & fees
22 Nov - 23 Nov
InterContinental Houston by IHG
A rooftop pool area with lounge chairs and a view of a tall building at night.

2. The Westin Houston Medical Center/Museum District

The Westin Houston Medical Center/Museum District
4.0 star property
South Central Houston
9.2 out of 10, Wonderful, (1,284 reviews)
"Clean rooms great staff nice amenities overall amazing experience"
United States
Leonardo
The price is ฿4,853
฿6,041 total
includes taxes & fees
15 Nov - 16 Nov
The Westin Houston Medical Center/Museum District
A rooftop patio with outdoor seating, fire pits, and a view of the cityscape.

3. Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center
4.5 star property
South Central Houston
8.6 out of 10, Excellent, (2,246 reviews)
"Wonderful place to stay if you are going to the Medical Center."
United States
Cynthia
The price is ฿2,796
฿3,310 total
includes taxes & fees
22 Nov - 23 Nov
Hilton Houston Plaza/Medical Center
A modern hotel room with a large bed, a black leather sofa, a wooden coffee table, and a desk with a mirror.

4. Downtowner Inns - Houston Downtown

Downtowner Inns - Houston Downtown
2.0 star property
South Central Houston
9.2 out of 10, Wonderful, (276 reviews)
"Great place and close to downtown."
United States
Israel
The price is ฿3,222
฿3,770 total
includes taxes & fees
9 Nov - 10 Nov
Downtowner Inns - Houston Downtown
A spacious living area with a dining table, chairs, and a chandelier.

5. Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District
4.5 star property
South Central Houston
9.2 out of 10, Wonderful, (1,009 reviews)
"Wonderfully inviting and comfortable."
United States
Suzanne
The price is ฿6,475
฿9,167 total
includes taxes & fees
22 Nov - 23 Nov
Hotel Zaza Houston Museum District
A modern lobby with a reception desk, seating area, and a large abstract wall mural.

6. Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District
4.0 star property
South Central Houston
9.0 out of 10, Wonderful, (1,003 reviews)
"Wonderful!!"
United States
Vanessa
The price is ฿5,107
฿7,050 total
includes taxes & fees
22 Nov - 23 Nov
Houston Marriott Medical Center/Museum District
A spacious dining area with multiple tables and chairs, large windows, and hanging pendant lights.

7. DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites
4.0 star property
South Central Houston
8.4 out of 10, Very good, (721 reviews)
"Nice and convenient to the medical center"
United States
CHRISTY
The price is ฿3,826
฿4,476 total
includes taxes & fees
22 Nov - 23 Nov
DoubleTree by Hilton Houston Medical Center Hotel & Suites
A multi-story hotel with a brick facade, balconies, and a well-lit entrance.

8. La Maison in Midtown an urban B&B

La Maison in Midtown an urban B&B
3.5 star property
South Central Houston
9.8 out of 10, Exceptional, (608 reviews)
"The breakfast was fantastic. Property was clean. Staff is awesome"
United States
Justin
The price is ฿6,008
฿7,030 total
includes taxes & fees
17 Nov - 18 Nov
La Maison in Midtown an urban B&B
A high-rise hotel with a rooftop pool, multiple floors, and a cityscape view.

9. Sentral Forme Houston

Sentral Forme Houston
4.5 star property
South Central Houston
9.2 out of 10, Wonderful, (99 reviews)
"Enjoyable stay with all the comforts of home."
United States
ebony noelle
The price is ฿5,001
฿6,833 total
includes taxes & fees
30 Nov - 1 Dec
Sentral Forme Houston
A modern kitchen with dark wood cabinets, a granite countertop, and a built-in island with a glass enclosure.

10. Americas Best Value Inn Medical Center Downtown

Americas Best Value Inn Medical Center Downtown
2.0 star property
South Central Houston
8.0 out of 10, Very good, (1,000 reviews)
"Great Stay"
United States
Randy
The price is ฿3,272
฿3,828 total
includes taxes & fees
22 Nov - 23 Nov
Americas Best Value Inn Medical Center Downtown
A large, multi-story house with a swimming pool, outdoor seating, and a red umbrella.

11. Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
3.5 star property
South Central Houston
9.6 out of 10, Exceptional, (221 reviews)
"The room was very clean, the staff was just great and the breakfast was very good! The Parking was a little difficult, but it was very safe!"
United States
Walter
The price is ฿6,948
฿8,633 total
includes taxes & fees
9 Nov - 10 Nov
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
A modern kitchen with a large island, bar stools, and a stainless steel refrigerator.

12. Wanderstay Boutique Hotel

Wanderstay Boutique Hotel
3.0 star property
South Central Houston
9.8 out of 10, Exceptional, (83 reviews)
"Everything about our stay here was wonderful."
United States
jennifer k
The price is ฿4,400
฿5,148 total
includes taxes & fees
9 Nov - 10 Nov
Wanderstay Boutique Hotel
A spacious lobby with a large sectional sofa, a coffee table, and a reception desk.

13. Hilton University of Houston

Hilton University of Houston
3.5 star property
South Central Houston
9.0 out of 10, Wonderful, (996 reviews)
"Great stay!"
United States
Elizabeth
The price is ฿4,927
฿5,764 total
includes taxes & fees
23 Nov - 24 Nov
Hilton University of Houston
Private kitchen

14. 2824 Aeon Living

2824 Aeon Living
3.5 star property
South Central Houston
The price is ฿4,102
฿4,798 total
includes taxes & fees
12 Nov - 13 Nov
2824 Aeon Living
A hotel room with a bed, a dining table with chairs, a plant, and a coat rack.

15. 2820 Blodgett St

2820 Blodgett St
South Central Houston
The price is ฿3,021
฿3,534 total
includes taxes & fees
9 Nov - 10 Nov
2820 Blodgett St
A large outdoor swimming pool with a slide and multiple lanes, surrounded by a modern building with large windows.

16. Fifa 4BR Bundle Near NRG DT Med Center -12

Fifa 4BR Bundle Near NRG DT Med Center -12
2.0 star property
South Central Houston
The price is ฿15,673
฿28,894 total
includes taxes & fees
22 Nov - 23 Nov
Fifa 4BR Bundle Near NRG DT Med Center -12
A spacious lobby with a high ceiling, a central seating area with sofas and armchairs, a staircase leading to an upper level, and a flat-screen TV mounted on the wall.

17. Extended Stay America Suites Houston Med Ctr Braeswood Bl

Extended Stay America Suites Houston Med Ctr Braeswood Bl
2.5 star property
South Central Houston
6.2 out of 10, (1,002 reviews)
"The perfect place to stay!"
Mexico
Maria Fernanda
The price is ฿2,265
฿2,660 total
includes taxes & fees
6 Dec - 7 Dec
Extended Stay America Suites Houston Med Ctr Braeswood Bl
A hotel room with a bed, a desk, a chair, a mirror, a television, and a heater.

18. Scott Inn Suites - Downtown Houston

Scott Inn Suites - Downtown Houston
2.0 star property
South Central Houston
8.4 out of 10, Very good, (48 reviews)
"great value for money"
United States
Abdulmuiz
The price is ฿2,182
฿2,553 total
includes taxes & fees
12 Nov - 13 Nov
Scott Inn Suites - Downtown Houston
A hotel room with a bed, bedside table, desk, and a mirror.

19. Southmore Boulevard Motel

Southmore Boulevard Motel
2.0 star property
South Central Houston
5.8 out of 10, (245 reviews)
"Very sweet lady I will be back"
United States
LaKeara
The price is ฿1,964
฿2,297 total
includes taxes & fees
15 Nov - 16 Nov
Southmore Boulevard Motel
A modern reception area with a blackboard, a blue sofa, a yellow armchair, and a colorful rug.

20. Wanderstay Houston Hostel

Wanderstay Houston Hostel
2.0 star property
South Central Houston
8.2 out of 10, Very good, (220 reviews)
"Horrible do not stay here."
United States
Nathalia
The price is ฿2,316
฿2,710 total
includes taxes & fees
9 Nov - 10 Nov
Wanderstay Houston Hostel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels in South Central Houston

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A modern kitchen with a large island, bar stools, and a stainless steel refrigerator.
Wanderstay Boutique Hotel
3.0 star property
9.8
Exceptional
83 reviews
View
A multi-story hotel with a brick facade, balconies, and a well-lit entrance.
La Maison in Midtown an urban B&B
3.5 star property
9.8
Exceptional
608 reviews
View
A modern kitchen with dark cabinets, a stainless steel refrigerator, and a microwave.
Houston Lux Townhome
2.0 star property
9.8
Exceptional
9 reviews
View
A modern hotel room with a large bed, a black leather sofa, a wooden coffee table, and a desk with a mirror.
Downtowner Inns - Houston Downtown
2.0 star property
9.2
Wonderful
276 reviews
View
A large, multi-story house with a swimming pool, outdoor seating, and a red umbrella.
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
3.5 star property
9.6
Exceptional
221 reviews
View

Where to stay in South Central Houston

Find the best South Central Houston areas for the activities you enjoy most.
A bridge with the words "Welcome to Downtown Houston" and a star emblem.

Downtown Houston

Tour the beautiful green spaces, buzzing theater district and professional sports arenas nestled beneath a dramatic cityscape of gleaming skyscrapers.

A tall, modern building with a unique, vertical design, surrounded by trees and a partly cloudy sky.

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.

A cityscape with dense high-rise buildings, a river, and surrounding greenery.

Texas Medical Center

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

A city skyline with modern skyscrapers and a river flowing through a park.

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.

A modern cityscape with a tram and tall buildings.
Photo by George Zimzores
Open Photo by George Zimzores

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Downtown Transit Center Station.

Top South Central Houston Hotel Reviews

Hilton University of Houston

Hilton University of Houston

10/10 Excellent
"Our stay at the Hilton University of Houston was outstanding. The staff was attentive to our needs and the room was clean as a pin. It was so nice visiting our university kids and being able to stay so close to them on campus."
scott 2-night trip
Posted 5 hours ago
Hilton University of Houston

Frequently asked questions

What's it like in South Central Houston?
Travellers are sure to enjoy a stay in Houston's South Central Houston neighbourhood. Make sure that you visit TDECU Stadium and Children's Museum of Houston as part of your South Central Houston travel plans.
What's the best accommodation in South Central Houston?
Based on our traveller data, Hotel Zaza Houston Museum District is one of the top choices for your stay in South Central Houston. This hotel is a short 6-minute walk from Rice University, and it offers a full-service spa and a restaurant. Other good options for your stay in the area include Hilton Houston Plaza/Medical Center and The Westin Houston Medical Center/Museum District.
How many hotels can I expect to find in the South Central Houston area?
Expedia has 1272 hotels and other accommodation options in South Central Houston to choose from, making this an ideal home base for exploring the greater Houston area.
If I need to cancel my hotel reservation in South Central Houston, will I receive a refund?
Yes! Most room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best deals available in South Central Houston.
What is there to do around this Houston neighbourhood?
Spend some time exploring the great outdoors at Hermann Park, Cullen Sculpture Garden and Twilight Epiphany Skyspace. TDECU Stadium and Children's Museum of Houston are some other stops worth a visit in the neighbourhood. Daikin Park and Toyota Center are some popular places to visit in the area around South Central Houston. Shape Community Center and Project Row Houses are also worth a visit when you're out sightseeing in Houston.
How can I get around South Central Houston and the greater Houston area?
For a quick way to explore the city, catch a ride on metro transit at Elgin/Third Ward Station, TSU/UH Athletics District Station or Ensemble/HCC Station. If you want to venture out of town, M. D. Anderson Station is the closest train station. You can also catch a ride at Kinder Station.