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Find hotels in Sikeston, MO from ฿2,025

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Check prices for these dates

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5 Jan - 6 Jan
Tomorrow
6 Jan - 7 Jan
This weekend
9 Jan - 11 Jan
Next weekend
16 Jan - 18 Jan

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Our top choices for Sikeston hotels

Lobby
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1011)
"This is one of the best properties. We are in the area often, it's the best."
United States
James
The price is ฿2,837
฿3,200 total
includes taxes & fees
11 Jan - 12 Jan
Drury Plaza Hotel Cape Girardeau Conference Center
Property amenity
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO
3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1005)
"Great place. Friendly staff clean"
United States
Jeff
The price is ฿2,837
฿3,261 total
includes taxes & fees
11 Jan - 12 Jan
Drury Inn & Suites Sikeston, MO
Free daily full breakfast
Best Western Plus Sikeston

Best Western Plus Sikeston

Best Western Plus Sikeston
2.5 star property
Sikeston
8.4 out of 10, Very good, (1007)
"Great stay, everything was clean and comfortable. "
United States
Charles
The price is ฿2,492
฿2,840 total
includes taxes & fees
9 Jan - 10 Jan
Best Western Plus Sikeston
Property amenity
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
3.0 star property
Jackson
9.0 out of 10, Wonderful, (682)
"Conveniently located, clean, friendly staff."
United States
Philip
The price is ฿2,653
฿2,871 total
includes taxes & fees
7 Jan - 8 Jan
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Lobby
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1006)
"Nice place for a stay at a reasonable price."
United States
Arthur
The price is ฿2,206
฿2,489 total
includes taxes & fees
10 Jan - 11 Jan
Pear Tree Inn Cape Girardeau Near the Medical Center
Exterior
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very good, (727)
"Clean room and easy access to room"
United States
Anne
The price is ฿1,749
฿1,994 total
includes taxes & fees
6 Jan - 7 Jan
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Exterior
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1003)
"Breakfast was very good and staff was extremely friendly and rooms were very clean "
United States
Rex
The price is ฿2,869
฿3,236 total
includes taxes & fees
11 Jan - 12 Jan
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Lobby
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

Pear Tree Inn Sikeston
2.5 star property
Sikeston
9.4 out of 10, Exceptional, (1007)
"Very clean, very friendly! We will be staying again. "
United States
Beth
The price is ฿2,364
฿2,718 total
includes taxes & fees
11 Jan - 12 Jan
Pear Tree Inn Sikeston
Lobby
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (476)
"Very nice hotel within walking distance to many good restaurants "
United States
Vicky
The price is ฿3,591
฿4,069 total
includes taxes & fees
25 Jan - 26 Jan
Courtyard by Marriott Cape Girardeau Downtown
Lobby
Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (147)
"Lovely staff clean hotel comfortable beds "
United States
Kastriot
The price is ฿2,774
฿3,130 total
includes taxes & fees
25 Jan - 26 Jan
Fairfield Inn & Suites by Marriott Cape Girardeau
Lobby
Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North

Quality Inn Cape Girardeau North
2.5 star property
Cape Girardeau
7.2 out of 10, Good, (689)
"The room was clean and nice. The breakfast was really good."
United States
Kalani
The price is ฿1,867
฿2,106 total
includes taxes & fees
15 Jan - 16 Jan
Quality Inn Cape Girardeau North
Lobby
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1005)
"Breakfast was great- staff was welcoming. Will stay there again."
United States
Laura
The price is ฿2,616
฿2,766 total
includes taxes & fees
6 Jan - 7 Jan
Drury Inn & Suites Jackson MO
Exterior
Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very good, (283)
"The hotel was very clean, beds were comfortable, and staff was friendly and helpful."
United States
aileen
The price is ฿2,787
฿3,176 total
includes taxes & fees
11 Jan - 12 Jan
Comfort Inn & Suites Sikeston I-55
Exterior
Hampton Inn Sikeston

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (456)
"Very clean and super friendly staff!"
United States
Katherine
The price is ฿3,178
฿3,599 total
includes taxes & fees
11 Jan - 12 Jan
Hampton Inn Sikeston
Lobby
Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West
2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1003)
"Very clean and updated bathroom, clean room; outstanding hot breakfast and friendly staff."
United States
Colleen
The price is ฿2,206
฿2,489 total
includes taxes & fees
11 Jan - 12 Jan
Pear Tree Inn Cape Girardeau West
Breakfast, lunch, dinner served; American cuisine
Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter

Travelodge by Wyndham Dexter
2.0 star property
Dexter
7.6 out of 10, Good, (390)
"Clean room, friendly staff and quiet stay."
United States
Margo
The price is ฿2,483
฿2,788 total
includes taxes & fees
8 Jan - 9 Jan
Travelodge by Wyndham Dexter
Exterior
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (445)
"Stay was excellent "
United States
Kourtney
The price is ฿2,932
฿3,319 total
includes taxes & fees
11 Jan - 12 Jan
Holiday Inn Express & Suites Sikeston Southwest by IHG
Lobby sitting area
The Riverview

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (484)
" Excellent stay. Will come again"
United States
joydeep
The price is ฿3,036
฿3,425 total
includes taxes & fees
6 Jan - 7 Jan
The Riverview
Business centre
Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau

Drury Inn & Suites Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1009)
"Awesome stay!"
United States
Breckin
The price is ฿2,837
฿3,200 total
includes taxes & fees
11 Jan - 12 Jan
Drury Inn & Suites Cape Girardeau
Room, 2 Queen Beds
Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau

Tru By Hilton Cape Girardeau
2.5 star property
Cape Girardeau
9.6 out of 10, Exceptional, (104)
"It was a nice stay"
United States
Douglas
The price is ฿2,818
฿3,207 total
includes taxes & fees
14 Jan - 15 Jan
Tru By Hilton Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Sikeston attractions

City of Miner Convention Center

This versatile 16,000-square-foot venue in Miner, Missouri hosts conferences, weddings, and community gatherings. Modern meeting rooms and a commercial kitchen make it ideal for various events.
See properties

Sikeston Depot Museum

3.8/5 (33 reviews)
Housed in a restored 1916 train depot, this museum showcases Sikeston's cotton-growing heritage and local art. Explore regional history through rotating exhibits while admiring the building's National Register status.
See properties

Sikeston and related destinations

Home to Lambert's Café, the 'Home of Throwed Rolls,' where servers toss fresh bread across the room to hungry diners. Visit the historic Sikeston Depot or catch the annual rodeo where professional cowboys compete in thrilling events each August.

See all hotels in Sikeston
The best restaurant I have EVER been to! Hands down!!!
Photo by Ryan Coleman
Open Photo by Ryan Coleman

Top Sikeston Hotel Reviews

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

10/10 Excellent
"Nice man and good hotel"
colette 1-night trip
Posted 4 days ago
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

More cheap stays in Sikeston

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

220 S Interstate Dr Sikeston MO
The price is ฿1,983 per night from 11 Jan to 12 Jan
฿1,983
฿2,260 total
11 Jan - 12 Jan
includes taxes & fees
7.2/10 Good! (1,002 reviews)

Frequently asked questions

Where is the best place to stay in Sikeston?
Fairfield Inn & Suites by Marriott Sikeston is ranked highly by Expedia customers. This hotel offers free breakfast and a restaurant. Other top choices based on reviews include Pear Tree Inn Sikeston and Drury Inn & Suites Sikeston, MO. See all available top hotels, or vacation rentals in Sikeston.
If I need to cancel my hotel reservation in Sikeston, will I receive a refund?
Yes, you'll find most room reservations are refundable provided that you cancel before the accommodation's cancellation deadline, which is usually within 24-48 hours of your arrival date. If your reservation is non-refundable, you might be able to cancel it and be given a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Sikeston.
What's the best budget-friendly hotel in Sikeston?
Based on reviews, Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) is a popular hotel for our travellers who want a more economical choice, and features free breakfast and free Wi-Fi. View all budget hotels in Sikeston.
What's the best family accommodation in Sikeston?
Drury Inn & Suites Sikeston, MO is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Pear Tree Inn Sikeston is another good choice for your family trip. Find more child-friendly accommodations in Sikeston.
What's the best LGBTQ-friendly hotel in Sikeston?
Drury Inn & Suites Sikeston, MO is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Pear Tree Inn Sikeston and Hampton Inn Sikeston are two other good choices for your holiday. See all available hotels listed as LGBTQ-friendly in Sikeston.
What's the best dog-friendly hotel in Sikeston?
Drury Inn & Suites Sikeston, MO is a top hotel for people travelling with their pets, and offers an indoor pool and free WiFi for its human guests. Other good choices for you and your pet's trip include Hampton Inn Sikeston and Pear Tree Inn Sikeston. See more pet-friendly hotel accommodations in Sikeston.
What are some hotels with pools in Sikeston?
Best Western Plus Sikeston is a top hotel with a pool, free full breakfast and free self-parking. TownePlace Suites by Marriott Sikeston is another choice with an on-site pool. View all hotels with pools in Sikeston.
What is staying in Sikeston like?
Families will find child-friendly activities in Sikeston, and visitors give high marks for the top-notch restaurants and shopping. This welcoming city also attracts tourists with its riverfront and university setting. In Sikeston, there are 15 hotels and other accommodation options to choose from. Find out more about Sikeston.
What is there to see in Sikeston?
A couple of favourite places to visit are Sikeston Depot Museum and Central Park. You'll also find Front Street Studio & Art Gallery and Stoddard County Civil War Memorial Cemetery in the area. Take a look at what more there is to see and do in Expedia's Sikeston guide.
What's the seasonal weather in Sikeston?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Sikeston is 1536 mm.

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