Guadalupe District Travel Guide

Santa Fe

A train station with tracks, a Santa Fe Railway building, and wooden poles.
A church with a cross on top, a bell tower, and a sign that reads "San Miguel."
A wooden water tower labeled "Santa Fe Rail Yard" with a crowd of people and a bicycle in the foreground.
A statue of an angel atop a tiled archway with inscriptions.
A train station named 'Santa Fe Railyard' with a covered waiting area and a platform.

Stay near popular Guadalupe District attractions

Santa Fe Railyard

8.8/10 (1,473 reviews)
During your visit to Santa Fe, you can do some window-shopping at Santa Fe Railyard. Experience the fascinating museums and acclaimed art galleries in this romantic area.
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Things to do

Santa Fe: Meow Wolf's House of Eternal Return Ticket

Santa Fe: Meow Wolf The House of Eternal Return Ticket

฿1,683
per adult
100% of travellers recommend
Santa Fe: Meow Wolf The House of Eternal Return Ticket
Meow Wolf's House of Eternal Return

Meow Wolf's House of Eternal Return

฿1,248
per adult
80% of travellers recommend
Meow Wolf's House of Eternal Return
Hot Air Balloon Rides in Santa Fe

Hot Air Balloon Rides in Santa Fe

฿10,424
per adult
Hot Air Balloon Rides in Santa Fe
Santa Fe: Canyon Road Arts District Walking Tour

Santa Fe: Canyon Road Art & History Walking Tour

฿2,316
per adult
100% of travellers recommend
Santa Fe: Canyon Road Art & History Walking Tour
Santa Fe Historic Self-Guided Audio Walking Tour

Santa Fe Historic Self-Guided Audio Walking Tour

฿496
per adult
Santa Fe Historic Self-Guided Audio Walking Tour
In my happy place, among Northern New Mexico's amazing plants.

A Sensory and Spiritual Plant Workshop in Santa Fe

฿4,137
per adult
A Sensory and Spiritual Plant Workshop in Santa Fe
See all activities in Santa Fe

Top hotels in Guadalupe District

Guadalupe Inn

Guadalupe Inn

2 out of 5
604 Agua Fria St. Santa Fe NM
The price is ฿3,576 per night from 15 Sept to 16 Sept
฿3,576
฿4,219 total
15 Sept - 16 Sept
includes taxes & fees
Stay at this hotel in Santa Fe. Enjoy free Wi-Fi, parking (surcharge) and a business centre. Our guests praise the helpful staff in their reviews. Popular attractions ...
9.2/10 Wonderful! (1,000 reviews)
"Cute, quiet and walking distance to very good restaurants!! Rooms were spacious, outside balcony and tub were nice! Truly enjoyed the quaint ambience that was very different from the standard cookie cutter hotel. Will definitely go back when I revisit the area!!"

Reviewed on 10 Sept 2026

Guadalupe Inn
The Sage Hotel

The Sage Hotel

3 out of 5
725 Cerrillos Rd Santa Fe NM
Fully refundableReserve now, pay when you stay
The price is ฿2,991 per night from 29 Sept to 30 Sept
฿2,991
฿3,942 total
29 Sept - 30 Sept
includes taxes & fees
Stay at this business-friendly hotel in Santa Fe. Enjoy an outdoor pool, room service and a 24-hour fitness centre. Our guests praise the breakfast and the restaurant ...
The Sage Hotel
Eldorado Hotel & Spa

Eldorado Hotel & Spa

4 out of 5
309 W San Francisco Street Santa Fe NM
The price is ฿7,190 per night from 13 Sept to 14 Sept
฿7,190
฿9,441 total
13 Sept - 14 Sept
includes taxes & fees
Stay at this spa hotel in Santa Fe. Enjoy a full-service spa, 2 hot tubs and 2 bars/lounges. Our guests praise the helpful staff in their reviews. Popular attractions ...
8.8/10 Excellent! (1,488 reviews)
"The staff was very hospitable and friendly. We enjoyed our stay at this beautiful hotel. We will definitely return next fall. We highly recommend it."

Reviewed on 11 Sept 2026

Eldorado Hotel & Spa
Coyote South

Coyote South

3.5 out of 5
3358 Cerrillos Rd Santa Fe NM
The price is ฿2,683 per night from 28 Sept to 29 Sept
฿2,683
฿3,422 total
28 Sept - 29 Sept
includes taxes & fees
Stay at this business-friendly hotel in Santa Fe. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in ...
Coyote South
Hilton Santa Fe Buffalo Thunder

Hilton Santa Fe Buffalo Thunder

4 out of 5
20 Buffalo Thunder Trl Santa Fe NM
The price is ฿5,623 per night from 1 Oct to 2 Oct
฿5,623
฿6,427 total
1 Oct - 2 Oct
includes taxes & fees
Stay at this spa resort in Santa Fe. Enjoy free parking, an outdoor pool and a full-service spa. Our guests praise the helpful staff and the clean rooms in their ...
8.8/10 Excellent! (1,256 reviews)
"Its a really nice place. Im just not lucky so the machines were not nice to me."

Reviewed on 11 Sept 2026

Hilton Santa Fe Buffalo Thunder
La Fonda on the Plaza

La Fonda on the Plaza

4 out of 5
100 E San Francisco St Santa Fe NM
The price is ฿11,299 per night from 14 Sept to 15 Sept
฿11,299
฿13,015 total
14 Sept - 15 Sept
includes taxes & fees
Stay at this luxury hotel in Santa Fe. Enjoy free Wi-Fi, 2 restaurants and 2 bars/lounges. Our guests praise the restaurant and the helpful staff in their reviews. ...
9.4/10 Exceptional! (1,276 reviews)
"Great comfortable property"

Reviewed on 11 Sept 2026

La Fonda on the Plaza
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Guadalupe District

Find the best Guadalupe District areas for the activities you enjoy most.
A building with a distinctive architectural style, featuring a tower and a covered entrance.

Downtown Santa Fe

Visitors to Downtown Santa Fe rave about its fascinating museums, popular shops and acclaimed art galleries. You might also want to make some time to see Santuario De Nuestra Senora de Guadalupe or Lensic Performing Arts Center while you're exploring the neighbourhood.

A building with the sign 'Palace of the Governors' and flags hanging overhead.

Southside

Southside is known for its popular shops, and with sights like Meow Wolf and International Museum of Collage, Assemblage & Construction, you won't get bored spending a day wandering around this part of Santa Fe.

A Turner Carroll Gallery with a red door and a metal roof.

Historic Eastside

While visiting Historic Eastside, you might make a stop by sights like Canyon Road and ViVO Contemporary.

A church with two bell towers and a large circular window.

Northeast Santa Fe

While Northeast Santa Fe isn't home to many top sights, New Mexico Museum of Art and Cathedral Basilica of Saint Francis of Assisi are some notable places to visit nearby.

A performer in a white costume with a mask on a stage with fire effects.
Photo by Kate Cadwell
Open Photo by Kate Cadwell

North Hills

While there might not be top attractions in North Hills, you can explore the larger area and discover places like Canyon Road and Cathedral Basilica of Saint Francis of Assisi.

Guadalupe District Travel Guide