Santa Clara Packages (Flight + Hotel)

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    Save up to ฿4,531 when you book a flight and hotel together*
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Top hotels in Santa Clara

Hotel Riu Plaza Panama

Hotel Riu Plaza Panama

5 out of 5
Calle 50, Urb. Marbella, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is ฿3,507 per night from 25 Aug to 26 Aug
฿3,507
฿3,858 total
25 Aug - 26 Aug
includes taxes & fees
9/10 Wonderful! (4,125 reviews)
"The property, personel. accessibility to places and food were all excellent."

Reviewed on 31 Jul 2025

Hotel Riu Plaza Panama
Sheraton Grand Panama

Sheraton Grand Panama

4 out of 5
Via Israel And 77th Street, Panama City, Panama
Fully refundableReserve now, pay when you stay
The price is ฿4,359 per night from 10 Aug to 11 Aug
฿4,359
฿4,795 total
10 Aug - 11 Aug
includes taxes & fees
8.4/10 Very Good! (914 reviews)
"Me and my husband loved staying there! Superb hotel beyond international standards! The staff was so friendly and attentive. The hotel is gorgeous! The pool is amazing and so is the spa. The breakfast buffet is excellent. I only have the best words to describe this place! I hope to stay there when ..."

Reviewed on 26 Jul 2025

Sheraton Grand Panama
Waymore Hotel Spa & Casino

Waymore Hotel Spa & Casino

4 out of 5
Calle Augusto Samuel Boyd y Calle Eusebi, Panama City
Fully refundableReserve now, pay when you stay
The price is ฿2,604 per night from 16 Aug to 17 Aug
฿2,604
฿2,864 total
16 Aug - 17 Aug
includes taxes & fees
9/10 Wonderful! (374 reviews)
"Everything was going good until we went to the casino bar girsl didn't understand English and was very dismissive July 18th after 5:30pm. I feel at least one person on a shift should be able to understand and speak English. Environment was safe ,hotel rooms nice . Housekeeping when cleaning the rooms ..."

Reviewed on 30 Jul 2025

Waymore Hotel Spa & Casino
See all 1,494 properties in Santa Clara
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

What to do in Santa Clara

Panama City Tour and Panama Canal – Miraflores Locks Experience

Panama City Tour and Panama Canal – Miraflores Locks Experience

฿1,135
per adult
100% of travellers recommend
Panama City Tour and Panama Canal – Miraflores Locks Experience
Gatun Lake boat ride

Panama Canal Monkey & Wildlife Boat Safari

฿1,784
per adult
100% of travellers recommend
Panama Canal Monkey & Wildlife Boat Safari
Guided Jungle Adventure with Gatun Lake Cruise

Guided Jungle Adventure with Gatun Lake Cruise

฿2,887
per adult
88% of travellers recommend
Guided Jungle Adventure with Gatun Lake Cruise
See all activities in Santa Clara

Frequently asked questions

How much does a Santa Clara holiday package cost?
You can snap up a holiday package to this destination on Expedia. However, how much your holiday to Santa Clara costs will depend on your hotel choice, season and length of stay.
What are the cheapest months to go to Santa Clara?
If you're hoping to snag a cheap Santa Clara holiday package, consider travelling in September, October and November. You're likely to find lower rates on accommodation and flights during these quieter months — ideal for a budget-friendly break.
How many days is enough for Santa Clara?
With a well-organised travel plan, you can easily tick off the top Santa Clara attractions in a few days. But if you prefer to discover hidden spots or go on day trips, think about booking your Santa Clara holiday for longer.
How to find the best Santa Clara package deals?
Landing a cheap Santa Clara package deal is easy with Expedia. After you've entered your preferred dates and destination under our "Packages" tab, set your maximum budget, add a few filters and browse what's available. You can tweak your search by "Property class," "Number of bedrooms," "Traveller experience" and more. Sort the results by "Price: low to high" to view the most affordable Santa Clara package deals. Want a simple trick to score even more savings? Have some flexibility with your departure dates and consider travelling on a weekday, when prices are generally lower.
Is it cheaper to book a Santa Clara holiday as a package?
An Expedia holiday package could land you significant savings when compared to arranging flights and stays separately. Better still, you can customise your Santa Clara trip to fit your exact style. Choose your preferred flight time, select the hotel type and add a rental car. Check out our great deals to see how much you can save.
When to book a holiday package to Santa Clara?
If you have your Santa Clara holiday dates finalized, book as early as you can to bag some incredible deals. With Expedia, you can generally reserve some flights up to one year in advance. Prefer spontaneous getaways? Our last-minute deals are perfect for quick escapes.
How to plan a trip to Santa Clara?

  1. Choose when to go: Check your schedule and get your bags packed. Your favourite time of year and the available activities will also help you decide when to escape to Santa Clara.
  2. Set a budget: Factor in costs like flights, meals and transportation when calculating how much to set aside for your trip to Santa Clara. Then, pick a hotel that matches your budget, whether that's an economical option or a lavish retreat.
  3. Decide how many days away: Start by listing all the activities and attractions you want to experience in Santa Clara. Then, estimate how long you'll need at each, as well as any travel time.
  4. Combine your airfare and accommodation: Once you've nailed down your travel dates and duration, book the perfect Santa Clara holiday package for you.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.