Search Hotels in Sanibel Isles, Sanibel

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Our top choices for Sanibel Isles hotels

The Anchor Inn

The Anchor Inn
2.0 star property
Mid Island, 2.3 km from Sanibel Isles
9.8 out of 10, Exceptional, (6 reviews)
"This hotel was perfect It was decorated beautifully and was so clean and the bed was so comfy and the rainfall shower was very nice, the room had everything you could need for a nice vacation there’s a market within walking distance which had everything you need to make your stay perfect highly recommend this hotel anytime we come back to Sanibel we will always stay here "
United States
Mary
The price is ฿10,380
฿12,052 total
includes taxes & fees
8 Apr - 9 Apr
The Anchor Inn

Matlacha on Shoreview

Matlacha on Shoreview
2.0 star property
19.4 km from Sanibel Isles
9.6 out of 10, Exceptional, (240 reviews)
"Beautiful resort, great communication, super clean "
United States
Ronald
The price is ฿3,155
฿5,651 total
includes taxes & fees
18 Mar - 19 Mar
Matlacha on Shoreview

Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers

Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers
3.0 star property
25.4 km from Sanibel Isles
9.4 out of 10, Exceptional, (770 reviews)
"Clean room, great amenities, good breakfast "
United States
Maitte
The price is ฿4,172
฿4,652 total
includes taxes & fees
2 Apr - 3 Apr
Fairfield Inn & Suites by Marriott Cape Coral/North Fort Myers

The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village
4.0 star property
10.1 km from Sanibel Isles
9.0 out of 10, Wonderful, (1,007 reviews)
"Amazing room and view. Great place to stay/vacation. Would come back over and over again. "
United States
Frank
The price is ฿7,595
฿9,743 total
includes taxes & fees
5 Apr - 6 Apr
The Westin Cape Coral Resort At Marina Village

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL
2.5 star property
14.5 km from Sanibel Isles
8.8 out of 10, Excellent, (1,005 reviews)
"Room was clean and staff was fantastic "
United States
Wayne
The price is ฿3,633
฿4,051 total
includes taxes & fees
5 Apr - 6 Apr
Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Dolphin Key Resort

Dolphin Key Resort
3.0 star property
15.3 km from Sanibel Isles
8.8 out of 10, Excellent, (1,249 reviews)
"Nice room, great tiki bar and pool area, and friendly staff."
United States
Jason
The price is ฿3,187
฿3,554 total
includes taxes & fees
1 Apr - 2 Apr
Dolphin Key Resort

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Holiday Inn Express Cape Coral-Fort Myers Area by IHG
2.5 star property
15.5 km from Sanibel Isles
9.2 out of 10, Wonderful, (1,286 reviews)
"Good place to stay"
United States
Rashad
The price is ฿3,219
฿3,590 total
includes taxes & fees
5 Apr - 6 Apr
Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Park Motel

Park Motel
2.5 star property
30.1 km from Sanibel Isles
9.4 out of 10, Exceptional, (37 reviews)
"Clean, quiet, very friendly and helpful staff, hot tub in room very relaxing."
United States
Kristeen
The price is ฿3,347
฿3,732 total
includes taxes & fees
1 Apr - 2 Apr
Park Motel

Off the Charts Inn & Out Island Resort

Off the Charts Inn & Out Island Resort
2.5 star property
5.1 km from Sanibel Isles
9.6 out of 10, Exceptional, (153 reviews)
"Nice new rooms and great outdoor seating on the waterway, we saw lots of manatees "
United States
Ellen
The price is ฿5,044
฿6,690 total
includes taxes & fees
1 Apr - 2 Apr
Off the Charts Inn & Out Island Resort

Tween Waters Island Resort & Spa

Tween Waters Island Resort & Spa
3.0 star property
14.4 km from Sanibel Isles
8.6 out of 10, Excellent, (1,006 reviews)
"Lovely location, pools and restaurants."
United States
Linda
The price is ฿15,299
฿18,174 total
includes taxes & fees
4 Apr - 5 Apr
Tween Waters Island Resort & Spa

SpringHill Suites by Marriott Fort Myers Estero

SpringHill Suites by Marriott Fort Myers Estero
2.5 star property
27.3 km from Sanibel Isles
9.2 out of 10, Wonderful, (849 reviews)
"Great breakfast and nice clean room"
Canada
John
The price is ฿5,117
฿5,865 total
includes taxes & fees
1 Apr - 2 Apr
SpringHill Suites by Marriott Fort Myers Estero

Embassy Suites by Hilton Fort Myers Estero

Embassy Suites by Hilton Fort Myers Estero
3.5 star property
27.4 km from Sanibel Isles
9.2 out of 10, Wonderful, (1,138 reviews)
"Convenient location, quiet room, good breakfast. "
United States
Jeff
The price is ฿4,815
฿5,368 total
includes taxes & fees
1 Apr - 2 Apr
Embassy Suites by Hilton Fort Myers Estero

TownePlace Suites by Marriott Fort Myers Estero

TownePlace Suites by Marriott Fort Myers Estero
3.5 star property
25.8 km from Sanibel Isles
9.4 out of 10, Exceptional, (493 reviews)
"The staff was very accommodating. The location was wonderful, off the main roads but close to everything. I will definitely recommend to others and also stay there again."
United States
Susan
The price is ฿4,308
฿4,803 total
includes taxes & fees
5 Apr - 6 Apr
TownePlace Suites by Marriott Fort Myers Estero

Sunshine Island Inn

Sunshine Island Inn
2.5 star property
East End, 3.2 km from Sanibel Isles
9.0 out of 10, Wonderful, (295 reviews)
"Great stay. "
United States
Aundrea
Sunshine Island Inn

Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
Mid Island, 3.2 km from Sanibel Isles
9.2 out of 10, Wonderful, (1,665 reviews)
"Staff is amazing, amenities are great and is so beautiful! "
United States
Erica
The price is ฿14,630
฿17,109 total
includes taxes & fees
5 Apr - 6 Apr
Sanibel Island Beach Resort

Matlacha Tiny Village

Matlacha Tiny Village
3.0 star property
18.3 km from Sanibel Isles
8.8 out of 10, Excellent, (277 reviews)
"The property was super cute and clean! It also had just about anything you could need!"
United States
Wyatt
The price is ฿4,430
฿7,330 total
includes taxes & fees
23 Mar - 24 Mar
Matlacha Tiny Village

Drury Inn & Suites Fort Myers Airport FGCU

Drury Inn & Suites Fort Myers Airport FGCU
3.0 star property
26.4 km from Sanibel Isles
9.8 out of 10, Exceptional, (1,010 reviews)
"Always a great stay"
United States
David
The price is ฿3,729
฿4,158 total
includes taxes & fees
5 Apr - 6 Apr
Drury Inn & Suites Fort Myers Airport FGCU

The Banyan Hotel Fort Myers, Tapestry Collection by Hilton

The Banyan Hotel Fort Myers, Tapestry Collection by Hilton
3.5 star property
27 km from Sanibel Isles
8.6 out of 10, Excellent, (857 reviews)
"Great location and friendly staff."
United States
Matthew
The price is ฿5,985
฿6,673 total
includes taxes & fees
5 Apr - 6 Apr
The Banyan Hotel Fort Myers, Tapestry Collection by Hilton

Sundial Beach Resort & Spa

Sundial Beach Resort & Spa
5.0 star property
Mid Island, 3.5 km from Sanibel Isles
8.6 out of 10, Excellent, (2,604 reviews)
"Room was clean and was cleaned in the middle of our stay and staff was great."
United States
Glen
The price is ฿16,322
฿19,941 total
includes taxes & fees
10 Mar - 11 Mar
Sundial Beach Resort & Spa

Angler's Inn

Angler's Inn
2.5 star property
18.3 km from Sanibel Isles
9.4 out of 10, Exceptional, (325 reviews)
"Cute Inn in Matlacha. Clean rooms, comfy beds, and a great screened in porch for each room. Town still recovering from Ian, but still a great time. "
United States
Crystal
The price is ฿5,578
฿6,219 total
includes taxes & fees
10 Mar - 11 Mar
Angler's Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Sanibel Isles

Find the best Sanibel Isles areas for the activities you enjoy most.

Mid Island

If you're spending some time in Mid Island, Periwinkle Way and Sanibel Island Southern Beach are top sights worth seeing.

West End

If you're spending some time in West End, J. N. Ding Darling National Wildlife Refuge and Bowman's Beach are top sights worth seeing.

East End

While visiting East End, you might make a stop by sights like Sanibel Island Northern Beach and Sanibel Island Lighthouse.

Beachview Country Club Estates

While visiting Beachview Country Club Estates, you might make a stop by sights like Periwinkle Way and Sanibel Island Golf Club.

Sanctuary

While there might not be top attractions in Sanctuary, you can explore the larger area and discover places like Blind Pass Beach and Turner Beach.

Top Sanibel Isles Hotel Reviews

Frequently asked questions

What's it like in Sanibel Isles?
Travellers to the Sanibel Isles neighbourhood in Sanibel will be sure to enjoy their stay.
How many hotels should I expect to find in the Sanibel Isles area?
When you want to find places to stay in Sanibel, start by booking one of Expedia's 7 hotels and other accommodation options in Sanibel Isles.
If I need to cancel my hotel reservation in Sanibel Isles, will I receive a refund?
Yes! The majority of hotel room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and receive a refund within 24 hours of booking. Put your dates in and click on "Search", then filter by "fully refundable" to view top deals in Sanibel Isles.
What is there to do in this Sanibel neighbourhood?
Woodring Point, Woodring Beach and Dunes Golf and Tennis Club are just a few of the places to visit in and around Sanibel Isles. Bailey's Beach and Periwinkle Way are also worth a visit when you're out sightseeing in Sanibel.