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Our top choices for Sanibel Isles hotels

HomeTowne Studios by Red Roof Fort Myers

HomeTowne Studios by Red Roof Fort Myers
2.5 star property
26.4 km from Sanibel Isles
8.6 out of 10, Excellent, (16 reviews)
"This is a new hotel and everything was excellent!"
United States
Mercedes E
The price is ฿2,783
฿3,103 total
includes taxes & fees
23 Jun - 24 Jun
HomeTowne Studios by Red Roof Fort Myers

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort
3.5 star property
10.3 km from Sanibel Isles
9.0 out of 10, Wonderful, (1,615 reviews)
"Great place to stay!! We very much enjoyed it!!"
United States
Sherry
The price is ฿4,951
฿6,247 total
includes taxes & fees
23 Jun - 24 Jun
Lani Kai Beachfront Resort

Holiday Inn Express & Suites Fort Myers Airport by IHG

Holiday Inn Express & Suites Fort Myers Airport by IHG
2.5 star property
27.6 km from Sanibel Isles
9.6 out of 10, Exceptional, (1,092 reviews)
"Great staff, awesome airport shuttle!"
United States
Carlos
The price is ฿2,448
฿2,730 total
includes taxes & fees
3 Jul - 4 Jul
Holiday Inn Express & Suites Fort Myers Airport by IHG

The Bay Inn at Lani Kai

The Bay Inn at Lani Kai
3.0 star property
10.3 km from Sanibel Isles
7.8 out of 10, Good, (431 reviews)
"Enjoyed our stay!"
United States
Steve
The price is ฿4,072
฿5,267 total
includes taxes & fees
21 Jun - 22 Jun
The Bay Inn at Lani Kai

Pointe Estero Beach Resort

Pointe Estero Beach Resort
2.0 star property
15.8 km from Sanibel Isles
9.2 out of 10, Wonderful, (1,011 reviews)
"The beach view was amazing, very clean property"
United States
Kara
The price is ฿5,269
฿16,447 total
includes taxes & fees
18 Jun - 19 Jun
Pointe Estero Beach Resort

StudioRes by Marriott Fort Myers Airport

StudioRes by Marriott Fort Myers Airport
3.0 star property
25.4 km from Sanibel Isles
9.4 out of 10, Exceptional, (69 reviews)
"Excellent facility. Favorite place to stay"
United States
Daniel
The price is ฿2,463
฿2,746 total
includes taxes & fees
23 Jun - 24 Jun
StudioRes by Marriott Fort Myers Airport

Best Western Plus Beach Resort

Best Western Plus Beach Resort
2.5 star property
9.4 km from Sanibel Isles
9.4 out of 10, Exceptional, (1,009 reviews)
"Clean room, nice breakfast and right on the beach. Also within walking distance of restaurants & shops. Would definitely stay again!"
United States
AARON
The price is ฿6,927
฿7,724 total
includes taxes & fees
23 Jun - 24 Jun
Best Western Plus Beach Resort

Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina
4.0 star property
9 km from Sanibel Isles
9.4 out of 10, Exceptional, (1,399 reviews)
"Great place to visit"
United States
Karen
The price is ฿12,745
฿16,352 total
includes taxes & fees
20 Jun - 21 Jun
Pink Shell Beach Resort and Marina

Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
8.5 km from Sanibel Isles
8.8 out of 10, Excellent, (1,022 reviews)
"I would stay here again good breakfast nice heated pool good distance to beaches"
United States
Cheryl
The price is ฿3,093
฿3,448 total
includes taxes & fees
22 Jun - 23 Jun
Residence Inn by Marriott Fort Myers Sanibel

Hampton Inn Bonita Springs/Naples-North

Hampton Inn Bonita Springs/Naples-North
2.5 star property
28.9 km from Sanibel Isles
9.0 out of 10, Wonderful, (1,015 reviews)
"Hotel was clean, comfortable quiet great location to get to the beach old downtown Bonita and the restaurant Next-Door, aqua is exceptional as everything you need for a good getaway"
United States
randy
The price is ฿2,995
฿3,339 total
includes taxes & fees
18 Jun - 19 Jun
Hampton Inn Bonita Springs/Naples-North

The Anchor Inn

The Anchor Inn
2.0 star property
Mid Island, 2.3 km from Sanibel Isles
9.8 out of 10, Exceptional, (45 reviews)
"We had a great time and would definitely stay there again!"
United States
William Edward
The price is ฿6,933
฿8,219 total
includes taxes & fees
30 Jun - 1 Jul
The Anchor Inn

Latitude 26 Waterfront Boutique Resort - Bonita Springs

Latitude 26 Waterfront Boutique Resort - Bonita Springs
3.0 star property
26.8 km from Sanibel Isles
8.8 out of 10, Excellent, (799 reviews)
"Very convenient hotel to access Bonita Beach. The hotel staff was friendly, everything was clean, the location is beautiful with a dock on the water if you need to get picked up by a boat!"
United States
Colin
The price is ฿3,500
฿3,990 total
includes taxes & fees
18 Jun - 19 Jun
Latitude 26 Waterfront Boutique Resort - Bonita Springs

Park Motel

Park Motel
2.5 star property
30.1 km from Sanibel Isles
9.2 out of 10, Wonderful, (46 reviews)
"Clean, quiet, very friendly and helpful staff, hot tub in room very relaxing."
United States
Kristeen
The price is ฿3,076
฿3,430 total
includes taxes & fees
22 Jun - 23 Jun
Park Motel

Woodspring Suites Fort Myers - Cape Coral

Woodspring Suites Fort Myers - Cape Coral
2.5 star property
23.4 km from Sanibel Isles
7.4 out of 10, Good, (305 reviews)
"Nice place"
United States
najwa
The price is ฿2,461
฿2,744 total
includes taxes & fees
18 Jun - 19 Jun
Woodspring Suites Fort Myers - Cape Coral

Latitude 26 Waterfront Resort & Marina

Latitude 26 Waterfront Resort & Marina
3.0 star property
10.8 km from Sanibel Isles
8.6 out of 10, Excellent, (1,013 reviews)
"Nice and clean, friendly staff"
United States
Samuel
The price is ฿3,978
฿4,435 total
includes taxes & fees
18 Jun - 19 Jun
Latitude 26 Waterfront Resort & Marina

Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
Mid Island, 3.2 km from Sanibel Isles
9.2 out of 10, Wonderful, (2,014 reviews)
"Great place to stay! This was our second time staying here and we will be back again!"
United States
Madison
The price is ฿7,780
฿9,489 total
includes taxes & fees
18 Jun - 19 Jun
Sanibel Island Beach Resort

Tween Waters Island Resort & Spa

Tween Waters Island Resort & Spa
3.0 star property
14.4 km from Sanibel Isles
8.6 out of 10, Excellent, (1,010 reviews)
"Great view, friendly staff!"
United States
Nicholas J
The price is ฿9,610
฿11,854 total
includes taxes & fees
10 Jul - 11 Jul
Tween Waters Island Resort & Spa

La Quinta Inn & Suites by Wyndham Bonita Springs Naples N.

La Quinta Inn & Suites by Wyndham Bonita Springs Naples N.
3.0 star property
29.4 km from Sanibel Isles
9.0 out of 10, Wonderful, (1,434 reviews)
"Very clean and very friendly staff. Decent breakfast. Great location. "
United States
Pete J
The price is ฿3,320
฿3,702 total
includes taxes & fees
21 Jun - 22 Jun
La Quinta Inn & Suites by Wyndham Bonita Springs Naples N.

Quality Inn Fort Myers Cape Coral

Quality Inn Fort Myers Cape Coral
2.0 star property
23 km from Sanibel Isles
7.6 out of 10, Good, (334 reviews)
"Clean room, nice breakfast and wonderful staff!"
United States
Christina
The price is ฿1,650
฿2,341 total
includes taxes & fees
8 Jul - 9 Jul
Quality Inn Fort Myers Cape Coral

Flamingo Inn

Flamingo Inn
3.0 star property
15.4 km from Sanibel Isles
7.8 out of 10, Good, (1,009 reviews)
"Very clean and a short walk to the ocean. The property manager accommodated everything we needed and was friendly. Definitely would recommend Flamingo Inn to everyone!"
United States
Cary
The price is ฿3,946
฿6,643 total
includes taxes & fees
17 Jun - 18 Jun
Flamingo Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Sanibel Isles

Find the best Sanibel Isles areas for the activities you enjoy most.

Mid Island

If you're spending some time in Mid Island, Sanibel Island Southern Beach and Periwinkle Way are top sights worth seeing.

West End

If you're spending some time in West End, Sanibel Island Southern Beach and J. N. Ding Darling National Wildlife Refuge are top sights worth seeing.

East End

While visiting East End, you might make a stop by sights like Sanibel Island Southern Beach and Sanibel Island Northern Beach.

Beachview Country Club Estates

While visiting Beachview Country Club Estates, you might make a stop by sights like Periwinkle Way and Sanibel Island Golf Club.

Sanctuary

While there might not be top attractions in Sanctuary, you can explore the larger area and discover places like Blind Pass Beach and Turner Beach.

Top Sanibel Isles Hotel Reviews

Frequently asked questions

What's it like in Sanibel Isles?
Travellers to the Sanibel Isles neighbourhood in Sanibel will be sure to enjoy their stay.
How many hotels should I expect to find in the Sanibel Isles area?
When you want to find places to stay in Sanibel, start by booking one of Expedia's 8 hotels and other accommodation options in Sanibel Isles.
If I need to cancel my hotel reservation in Sanibel Isles, will I receive a refund?
Yes! The majority of hotel room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and receive a refund within 24 hours of booking. Put your dates in and click on "Search", then filter by "fully refundable" to view top deals in Sanibel Isles.
What is there to do in this Sanibel neighbourhood?
Sanibel Island Southern Beach, Woodring Point and Woodring Beach are just a few of the places to visit in and around Sanibel Isles. Dunes Golf and Tennis Club and Bailey's Beach are also worth a visit when you're out sightseeing in Sanibel.