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Our top choices for Sanibel Isles hotels

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort
3.5 star property
10.3 km from Sanibel Isles
9.0 out of 10, Wonderful, (1,651 reviews)
"Great place to stay!! We very much enjoyed it!!"
United States
Sherry
The price is ฿5,900
฿7,313 total
includes taxes & fees
1 Jul - 2 Jul
Lani Kai Beachfront Resort

Holiday Inn Express & Suites Fort Myers Airport by IHG

Holiday Inn Express & Suites Fort Myers Airport by IHG
2.5 star property
27.6 km from Sanibel Isles
9.6 out of 10, Exceptional, (1,106 reviews)
"Great staff, awesome airport shuttle!"
United States
Carlos
The price is ฿2,742
฿3,058 total
includes taxes & fees
3 Jul - 4 Jul
Holiday Inn Express & Suites Fort Myers Airport by IHG

HomeTowne Studios by Red Roof Fort Myers

HomeTowne Studios by Red Roof Fort Myers
2.5 star property
26.4 km from Sanibel Isles
8.8 out of 10, Excellent, (21 reviews)
"This is a new hotel and everything was excellent!"
United States
Mercedes E
The price is ฿2,818
฿3,142 total
includes taxes & fees
30 Jun - 1 Jul
HomeTowne Studios by Red Roof Fort Myers

Quality Inn Fort Myers Cape Coral

Quality Inn Fort Myers Cape Coral
2.0 star property
23 km from Sanibel Isles
7.6 out of 10, Good, (342 reviews)
"Clean room, nice breakfast and wonderful staff!"
United States
Christina
The price is ฿1,383
฿1,962 total
includes taxes & fees
3 Jul - 4 Jul
Quality Inn Fort Myers Cape Coral

StudioRes by Marriott Fort Myers Airport

StudioRes by Marriott Fort Myers Airport
3.0 star property
25.4 km from Sanibel Isles
9.4 out of 10, Exceptional, (71 reviews)
"Excellent facility. Favorite place to stay"
United States
Daniel
The price is ฿2,244
฿2,502 total
includes taxes & fees
6 Jul - 7 Jul
StudioRes by Marriott Fort Myers Airport

Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
8.5 km from Sanibel Isles
8.8 out of 10, Excellent, (1,008 reviews)
"I would stay here again good breakfast nice heated pool good distance to beaches"
United States
Cheryl
The price is ฿3,131
฿3,491 total
includes taxes & fees
24 Jun - 25 Jun
Residence Inn by Marriott Fort Myers Sanibel

Hampton Inn Fort Myers-Airport & I-75

Hampton Inn Fort Myers-Airport & I-75
3.5 star property
26.9 km from Sanibel Isles
9.0 out of 10, Wonderful, (1,002 reviews)
"Great place to stay."
United States
Vanaja
The price is ฿2,996
฿3,341 total
includes taxes & fees
11 Jul - 12 Jul
Hampton Inn Fort Myers-Airport & I-75

Pointe Estero Beach Resort

Pointe Estero Beach Resort
2.0 star property
15.8 km from Sanibel Isles
9.2 out of 10, Wonderful, (1,007 reviews)
"The beach view was amazing, very clean property"
United States
Kara
The price is ฿5,335
฿16,652 total
includes taxes & fees
6 Jul - 7 Jul
Pointe Estero Beach Resort

Woodspring Suites Fort Myers - Cape Coral

Woodspring Suites Fort Myers - Cape Coral
2.5 star property
23.4 km from Sanibel Isles
7.6 out of 10, Good, (307 reviews)
"Nice place"
United States
najwa
The price is ฿1,961
฿2,186 total
includes taxes & fees
24 Jun - 25 Jun
Woodspring Suites Fort Myers - Cape Coral

Pink Shell Beach Resort and Marina

Pink Shell Beach Resort and Marina
4.0 star property
9 km from Sanibel Isles
9.4 out of 10, Exceptional, (1,390 reviews)
"Great place to visit"
United States
Karen
The price is ฿8,276
฿11,396 total
includes taxes & fees
14 Jul - 15 Jul
Pink Shell Beach Resort and Marina

Extended Stay America Premier Suites - Fort Myers - Airport

Extended Stay America Premier Suites - Fort Myers - Airport
2.5 star property
21.8 km from Sanibel Isles
8.8 out of 10, Excellent, (1,041 reviews)
"very nice place to stay!"
United States
Natalia
The price is ฿1,957
฿2,183 total
includes taxes & fees
28 Jun - 29 Jun
Extended Stay America Premier Suites - Fort Myers - Airport

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
2.5 star property
12.1 km from Sanibel Isles
9.2 out of 10, Wonderful, (1,002 reviews)
"Great location"
United States
Kenneth A.
The price is ฿2,769
฿3,087 total
includes taxes & fees
30 Jun - 1 Jul
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park
2.0 star property
28 km from Sanibel Isles
8.0 out of 10, Very good, (1,696 reviews)
"Everything was very clean, good location. It was just a short stay but very pleasant."
United States
Robert
The price is ฿2,284
฿2,547 total
includes taxes & fees
25 Jun - 26 Jun
Days Inn & Suites by Wyndham Fort Myers Near JetBlue Park

Americas Best Value Inn Ft. Myers

Americas Best Value Inn Ft. Myers
3.0 star property
21.9 km from Sanibel Isles
7.6 out of 10, Good, (1,255 reviews)
"Very safe and many security cameras around facility"
United States
Mark
The price is ฿2,172
฿2,422 total
includes taxes & fees
13 Jul - 14 Jul
Americas Best Value Inn Ft. Myers

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway
3.0 star property
9.1 km from Sanibel Isles
8.2 out of 10, Very good, (1,225 reviews)
"I have stayed here many times it is clean, reasonably priced and local to the island"
United States
Gabriel
The price is ฿2,549
฿2,843 total
includes taxes & fees
6 Jul - 7 Jul
La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

TownePlace Suites by Marriott Fort Myers Gulf Coast

TownePlace Suites by Marriott Fort Myers Gulf Coast
3.0 star property
25.8 km from Sanibel Isles
9.2 out of 10, Wonderful, (215 reviews)
"Great staff and property."
United States
Shannon
The price is ฿3,230
฿3,602 total
includes taxes & fees
5 Jul - 6 Jul
TownePlace Suites by Marriott Fort Myers Gulf Coast

Hampton Inn Bonita Springs/Naples-North

Hampton Inn Bonita Springs/Naples-North
2.5 star property
28.9 km from Sanibel Isles
9.0 out of 10, Wonderful, (1,009 reviews)
"Hotel was clean, comfortable quiet great location to get to the beach old downtown Bonita and the restaurant Next-Door, aqua is exceptional as everything you need for a good getaway"
United States
randy
The price is ฿3,032
฿3,381 total
includes taxes & fees
28 Jun - 29 Jun
Hampton Inn Bonita Springs/Naples-North

Doubletree by Hilton Fort Myers at Bell Tower Shops

Doubletree by Hilton Fort Myers at Bell Tower Shops
4.0 star property
20.9 km from Sanibel Isles
9.0 out of 10, Wonderful, (1,149 reviews)
"Great stay"
United States
Marlon
The price is ฿3,216
฿3,586 total
includes taxes & fees
12 Jul - 13 Jul
Doubletree by Hilton Fort Myers at Bell Tower Shops

Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
Mid Island, 3.2 km from Sanibel Isles
9.2 out of 10, Wonderful, (2,043 reviews)
"Great place to stay! This was our second time staying here and we will be back again!"
United States
Madison
The price is ฿7,548
฿9,240 total
includes taxes & fees
25 Jun - 26 Jun
Sanibel Island Beach Resort

The Anchor Inn

The Anchor Inn
2.0 star property
Mid Island, 2.3 km from Sanibel Isles
9.8 out of 10, Exceptional, (47 reviews)
"We had a great time and would definitely stay there again!"
United States
William Edward
The price is ฿7,020
฿8,322 total
includes taxes & fees
19 Jul - 20 Jul
The Anchor Inn
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Sanibel Isles

Find the best Sanibel Isles areas for the activities you enjoy most.

Mid Island

If you're spending some time in Mid Island, Sanibel Island Southern Beach and Periwinkle Way are top sights worth seeing.

West End

If you're spending some time in West End, Sanibel Island Southern Beach and J. N. Ding Darling National Wildlife Refuge are top sights worth seeing.

East End

While visiting East End, you might make a stop by sights like Sanibel Island Southern Beach and Sanibel Island Northern Beach.

Beachview Country Club Estates

While visiting Beachview Country Club Estates, you might make a stop by sights like Periwinkle Way and Sanibel Island Golf Club.

Gulf Shores

When in Gulf Shores, you can plan a visit to Bowman's Beach and J. N. Ding Darling National Wildlife Refuge, some noteworthy sights in the nearby area.

Top Sanibel Isles Hotel Reviews

Frequently asked questions

What's it like in Sanibel Isles?
Travellers to the Sanibel Isles neighbourhood in Sanibel will be sure to enjoy their stay.
How many hotels should I expect to find in the Sanibel Isles area?
When you want to find places to stay in Sanibel, start by booking one of Expedia's 8 hotels and other accommodation options in Sanibel Isles.
If I need to cancel my hotel reservation in Sanibel Isles, will I receive a refund?
Yes! The majority of hotel room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might still have the option to cancel and receive a refund within 24 hours of booking. Put your dates in and click on "Search", then filter by "fully refundable" to view top deals in Sanibel Isles.
What is there to do in this Sanibel neighbourhood?
Sanibel Island Southern Beach, Woodring Point and Woodring Beach are just a few of the places to visit in and around Sanibel Isles. Dunes Golf and Tennis Club and Bailey's Beach are also worth a visit when you're out sightseeing in Sanibel.