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Our top choices for Sanibel Bayous hotels

In-room safe, desk, laptop workspace, blackout curtains
Shalimar Beach Resort

Shalimar Beach Resort

Shalimar Beach Resort
2.0 star property
West End, 6.1 km from Sanibel Bayous
10.0 out of 10, Exceptional, (18)
"Everything about this place was great "
United States
Andrew
The price is ฿14,836
฿16,542 total
includes taxes & fees
4 Jan - 5 Jan 2026
Shalimar Beach Resort
Exterior
Off the Charts Inn & Out Island Resort

Off the Charts Inn & Out Island Resort

Off the Charts Inn & Out Island Resort
2.5 star property
5.9 km from Sanibel Bayous
9.6 out of 10, Exceptional, (145)
"The facilities, although a little dated were very nice and spacious. The staff over the phone were very accomodating."
United States
Martin
The price is ฿7,985
฿9,955 total
includes taxes & fees
1 Jan - 2 Jan 2026
Off the Charts Inn & Out Island Resort
Outdoor pool
Sanibel Island Beach Resort

Sanibel Island Beach Resort

Sanibel Island Beach Resort
3.0 star property
Mid Island, 8.5 km from Sanibel Bayous
9.2 out of 10, Wonderful, (1500)
"Great place"
United States
Philip
The price is ฿8,197
฿9,931 total
includes taxes & fees
7 Jan - 8 Jan 2026
Sanibel Island Beach Resort
Exterior
Tarpon Tale Inn

Tarpon Tale Inn

Tarpon Tale Inn
3.0 star property
East End, 10.2 km from Sanibel Bayous
9.6 out of 10, Exceptional, (392)
"Great staff, close to the beach. Provided beach chairs, umbrella, & beach cart for stay. Highly recommend"
United States
Thomas
The price is ฿7,047
฿7,857 total
includes taxes & fees
21 Jan - 22 Jan 2026
Tarpon Tale Inn
Outdoor pool
Casa Ybel Resort

Casa Ybel Resort

Casa Ybel Resort
2.5 star property
Ybel, 7.2 km from Sanibel Bayous
8.6 out of 10, Excellent, (291)
"Room was amazing! Their video on their site is pre Hurricane Ian so don’t expect it to be like that ! Lots of devistation but they are working to bring it back. Most staff was nice , the front office staff were snotty and not helpful at !! Location on the beach is amazing! Sanibel / Captiva have captured my heart and I can’t wait to return. I’d stay there again . "
United States
Arra
The price is ฿14,784
฿16,484 total
includes taxes & fees
6 Jan - 7 Jan 2026
Casa Ybel Resort
Exterior
Sanibel Inn

Sanibel Inn

Sanibel Inn
3.0 star property
East End, 9.2 km from Sanibel Bayous
9.0 out of 10, Wonderful, (1003)
"Just beautiful! Couldn’t ask for a better stay in Sanibel "
United States
Jennifer Rebecca
The price is ฿11,111
฿14,213 total
includes taxes & fees
3 Jan - 4 Jan 2026
Sanibel Inn
Lobby
Tween Waters Island Resort & Spa

Tween Waters Island Resort & Spa

Tween Waters Island Resort & Spa
3.0 star property
8 km from Sanibel Bayous
8.6 out of 10, Excellent, (1000)
"Stunning Beach View great Staff "
United States
Robert
The price is ฿10,979
฿13,342 total
includes taxes & fees
7 Jan - 8 Jan 2026
Tween Waters Island Resort & Spa
2 outdoor pools, pool cabanas (surcharge), pool umbrellas
Sundial Beach Resort & Spa

Sundial Beach Resort & Spa

Sundial Beach Resort & Spa
5.0 star property
Mid Island, 8.2 km from Sanibel Bayous
8.6 out of 10, Excellent, (2584)
"wonderful family friendly and spotless resort"
United States
Mary Anne
The price is ฿11,580
฿14,630 total
includes taxes & fees
16 Jan - 17 Jan 2026
Sundial Beach Resort & Spa
3 outdoor pools, pool cabanas (surcharge), pool umbrellas
South Seas Resort

South Seas Resort

South Seas Resort
3.5 star property
9.5 km from Sanibel Bayous
8.4 out of 10, Very good, (1001)
"Fantastic place for perfect relaxation, hammocks are placed perfectly for a tropical feel staff is outstanding customer service. A top of the cap to Jeff and Anthony at the front desk."
United States
John
The price is ฿13,810
฿18,819 total
includes taxes & fees
4 Jan - 5 Jan 2026
South Seas Resort
On the beach, white sand, kayaking, motor boating
Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa

Marriott Sanibel Harbour Resort & Spa
4.0 star property
11.6 km from Sanibel Bayous
8.4 out of 10, Very good, (1002)
"Beautiful view from our room. Staff was courteous, friendly. Convenient access to sanibel. No real beach."
United States
Debbie
The price is ฿9,599
฿11,490 total
includes taxes & fees
9 Jan - 10 Jan 2026
Marriott Sanibel Harbour Resort & Spa
Suite with King Bed, Beachfront, Balcony | Terrace/patio
Lani Kai Beachfront Resort

Lani Kai Beachfront Resort

Lani Kai Beachfront Resort
3.5 star property
17.4 km from Sanibel Bayous
9.0 out of 10, Wonderful, (1055)
"Clean rooms lovely view of Beach and pool area."
United States
Laurice-Larry
The price is ฿4,814
฿6,073 total
includes taxes & fees
7 Jan - 8 Jan 2026
Lani Kai Beachfront Resort
View from property
Best Western Plus Beach Resort

Best Western Plus Beach Resort

Best Western Plus Beach Resort
2.5 star property
16.5 km from Sanibel Bayous
9.4 out of 10, Exceptional, (1002)
"Great place to stay."
United States
Michael
The price is ฿8,731
฿9,735 total
includes taxes & fees
14 Jan - 15 Jan 2026
Best Western Plus Beach Resort
Apartment, Multiple Beds, Partial Ocean View | Beach/ocean view
Edison Beach House

Edison Beach House

Edison Beach House
3.5 star property
16.7 km from Sanibel Bayous
9.4 out of 10, Exceptional, (1597)
"Awesome stay "
United States
mary
The price is ฿5,725
฿7,442 total
includes taxes & fees
3 Jan - 4 Jan 2026
Edison Beach House
Exterior
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
2.5 star property
19 km from Sanibel Bayous
9.4 out of 10, Exceptional, (1005)
"Spotless rooms , great breakfast , courteous staff ! Had a great time !"
United States
Arijit
The price is ฿4,310
฿4,805 total
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG
Outdoor pool, open 8:00 AM to 10:00 PM, pool cabanas (surcharge)
The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village

The Westin Cape Coral Resort At Marina Village
4.0 star property
15.1 km from Sanibel Bayous
9.0 out of 10, Wonderful, (1000)
"Clean resort, quiet and very friendly staff! Pools were amazing. "
United States
Jenny
The price is ฿6,391
฿8,384 total
includes taxes & fees
7 Jan - 8 Jan 2026
The Westin Cape Coral Resort At Marina Village
Outdoor pool
Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel

Residence Inn by Marriott Fort Myers Sanibel
3.0 star property
15.3 km from Sanibel Bayous
8.6 out of 10, Excellent, (1000)
"The property was clean and the breakfast was excellent the staff was friendly and convenient to Sanibel Island"
United States
robert
The price is ฿4,247
฿4,735 total
includes taxes & fees
4 Jan - 5 Jan 2026
Residence Inn by Marriott Fort Myers Sanibel
Deluxe Studio, 1 King Bed, Marina View | View from room
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
2.5 star property
17.3 km from Sanibel Bayous
8.8 out of 10, Excellent, (1000)
"Great Place to Stay!"
United States
JUDY
The price is ฿4,985
฿5,558 total
includes taxes & fees
5 Jan - 6 Jan 2026
Latitude 26 Waterfront Boutique Resort - Fort Myers Beach
Aerial view
DiamondHead Beach Resort

DiamondHead Beach Resort

DiamondHead Beach Resort
3.5 star property
17.9 km from Sanibel Bayous
9.2 out of 10, Wonderful, (1001)
"My daughter and I enjoyed our stay there! The beach was perfect, the pool was warm, and the staff was friendly and helpful!"
United States
Emilie Susan
DiamondHead Beach Resort
Bar (on property)
Matanzas Inn Bayside Resort and Marina

Matanzas Inn Bayside Resort and Marina

Matanzas Inn Bayside Resort and Marina
3.0 star property
17.1 km from Sanibel Bayous
9.2 out of 10, Wonderful, (1000)
"Rooms were very clean, and the staff was amazing."
United States
Deborah
The price is ฿6,921
฿8,503 total
includes taxes & fees
4 Jan - 5 Jan 2026
Matanzas Inn Bayside Resort and Marina
View from room
Matlacha on Shoreview

Matlacha on Shoreview

Matlacha on Shoreview
2.0 star property
20.1 km from Sanibel Bayous
9.6 out of 10, Exceptional, (216)
"Place was great. Nice and neat perfect for what i needed."
United States
Michael
The price is ฿2,057
฿4,411 total
includes taxes & fees
1 Jan - 2 Jan 2026
Matlacha on Shoreview
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Sanibel Bayous Hotel Reviews

Shalimar Beach Resort

Shalimar Beach Resort

10/10 Excellent
"Everything about this place was great "
Andrew 3-night trip
Posted 6 days ago
Shalimar Beach Resort

Hotels near other Sanibel Bayous attractions

Exploring J. N. Ding Darling National Wildlife Refuge in Sanibel, Florida with family and friends on a sunny day

J. N. Ding Darling National Wildlife Refuge

4.5/5 (355 reviews)
See almost anything that flies, swims or crawls in Florida in this protected area. Become acquainted with wildlife while learning about varied species.
See properties
Seashells on Sanibel Island, Florida

Sanibel Island Southern Beach

4.7/5 (808 reviews)
Why not spend a lazy afternoon at Sanibel Island Southern Beach during your trip to Sanibel?
See properties

Frequently asked questions

What's the area like around Sanibel Bayous?
Sanibel Bayous is located in Sanibel. You'll find 584 hotels and other accommodations within a few miles for a convenient home base.
Where is the best place to stay close to Sanibel Bayous?
Island Inn is one of the top choices for your stay based on our traveller data, and this aparthotel offers a private beach and free parking. It's located 3.4 mi (5.4 km) from Sanibel Bayous. Other good options within a few miles include Off the Charts Inn & Out Island Resort and Shalimar Beach Resort.
How many hotels will I be able to find close to Sanibel Bayous?
Expedia has 584 hotels and other accommodation options a few miles from Sanibel Bayous.
If I need to cancel the hotel reservation for my stay near Sanibel Bayous, will I receive a refund?
Yes, the majority of hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a reservation that's non-refundable, you might be able to cancel it and be given a refund within 24 hours of your booking. Enter dates in and click on "Search", then use the "fully refundable" filter to get the best deals near Sanibel Bayous.
What can I see and do near Sanibel Bayous?
Study the collections at Bailey - Matthews Shell Museum, Sanibel Historical Museum and Village or Sanibel Historical Village and Museum. You can enjoy live performances at BIG Arts Center and Herb Strauss Schoolhouse Theater. Enjoy a stroll along the shore at Bowman's Beach, Sanibel Island Southern Beach and Blind Pass Beach.