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Check prices for these dates

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15 Nov - 16 Nov
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16 Nov - 17 Nov
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20 Nov - 22 Nov
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27 Nov - 29 Nov

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Our top choices for Palazzo dello Spagnuolo hotels

A table with a croissant, a glass of milk, and a bowl of fruit on a tiled table in an outdoor setting.

1. Napoli Museo Bed and Breakfast

Napoli Museo Bed and Breakfast
Rione Sanità, 0.4 km from Palazzo dello Spagnuolo
9.6 out of 10, Exceptional, (45 reviews)
"Perfect clean room and amazing staff."
United States
Khaled
The price is ฿2,136
฿2,761 total
includes taxes & fees
17 Nov - 18 Nov
Napoli Museo Bed and Breakfast
A modern bathroom with a wooden sauna, a glass shower enclosure, and a window with a view.

2. Hermes Rooms for tourists

Hermes Rooms for tourists
Naples City Centre, 0.5 km from Palazzo dello Spagnuolo
9.8 out of 10, Exceptional, (99 reviews)
"Great location, very helpful staff (especially Mario who kept in good contact with us and gave us some great restaurant recommendations) as a family of 5, the family room was ideal, really clean and comfy. Would recommend this property."
United Kingdom
Julie
The price is ฿3,097
฿3,817 total
includes taxes & fees
16 Nov - 17 Nov
Hermes Rooms for tourists
A modern hotel room with a large bed, geometric wall art, a patterned floor, and a wooden headboard.

3. Ciao Bellini

Ciao Bellini
Decumani, 0.7 km from Palazzo dello Spagnuolo
9.8 out of 10, Exceptional, (96 reviews)
"It was a perfect 4 day stay in excellent location"
Canada
Alexandr
The price is ฿2,779
฿3,468 total
includes taxes & fees
16 Nov - 17 Nov
Ciao Bellini
A view through a window of a building with ornate architectural details and a clock tower.

4. The Other Duomo House

The Other Duomo House
Decumani, 0.6 km from Palazzo dello Spagnuolo
9.8 out of 10, Exceptional, (20 reviews)
"We had a wonderful stay in Naples! The room was spacious and very clean, and the staff were exceptionally friendly and welcoming. The breakfast was especially good, with plenty of delicious options to enjoy. We had a great experience and would happily stay here again."
United States
Zhiyun
The price is ฿2,475
฿3,134 total
includes taxes & fees
16 Nov - 17 Nov
The Other Duomo House
A modern building with a glass entrance, outdoor seating area with plants, and a tiled floor.

5. TERRAZZA CARBONARA B&B

TERRAZZA CARBONARA B&B
Naples City Centre, 0.7 km from Palazzo dello Spagnuolo
9.4 out of 10, Exceptional, (171 reviews)
"Very central location, great room and decent breakfast. Very friendly staff."
Canada
Khadeejah
The price is ฿1,746
฿2,331 total
includes taxes & fees
29 Nov - 30 Nov
TERRAZZA CARBONARA B&B
A buffet table with various food items, including a large cake, pastries, and a fruit bowl.

6. B&B Cupole e Campanili

B&B Cupole e Campanili
Decumani, 0.6 km from Palazzo dello Spagnuolo
9.8 out of 10, Exceptional, (217 reviews)
"Everything was just lovely"
Canada
Jelena
The price is ฿3,056
฿3,772 total
includes taxes & fees
18 Nov - 19 Nov
B&B Cupole e Campanili
A hotel room with a large window, a bed, a radiator, a TV, and a shelf with towels.

7. Decumano 43

Decumano 43
Decumani, 0.6 km from Palazzo dello Spagnuolo
10.0 out of 10, Exceptional, (6 reviews)
"Amazing stay with amazing hosts. Anna and Roberta are very accommodating and helpful."
United Kingdom
Jugraj
The price is ฿2,750
฿3,436 total
includes taxes & fees
17 Nov - 18 Nov
Decumano 43
A bedroom with a bed, a staircase, a chandelier, and a window with curtains.

8. The Duomo House

The Duomo House
Decumani, 0.6 km from Palazzo dello Spagnuolo
9.6 out of 10, Exceptional, (87 reviews)
"Great location. Very convenient. Perfect accommodation."
United Kingdom
Robin
The price is ฿2,475
฿3,134 total
includes taxes & fees
17 Nov - 18 Nov
The Duomo House
A spacious room with white marble flooring, two white armchairs with beige cushions, a small round table, and a door marked with the number 5.

9. Maison Museo Mann

Maison Museo Mann
Rione Sanità, 0.6 km from Palazzo dello Spagnuolo
10.0 out of 10, Exceptional, (5 reviews)
"Perfect! "
Germany
Maria
The price is ฿4,370
฿5,218 total
includes taxes & fees
16 Nov - 17 Nov
Maison Museo Mann
A rustic kitchen with a stone wall, a wooden table, and a clock on the wall.

10. Magma Home

Magma Home
Naples City Centre, 0.8 km from Palazzo dello Spagnuolo
9.8 out of 10, Exceptional, (54 reviews)
"Great breakfast, comfortable beds and good breakfast. Safe area "
United States
Marie
The price is ฿3,218
฿3,950 total
includes taxes & fees
16 Nov - 17 Nov
Magma Home
A breakfast table with croissants, pastries, and beverages, surrounded by wicker chairs.

11. Le Stanze del Principe

Le Stanze del Principe
Naples City Centre, 0.5 km from Palazzo dello Spagnuolo
9.2 out of 10, Wonderful, (547 reviews)
"We enjoyed our stay at Le Stanze del Principeor for its location, friendly staff, clean room and complimentary breakfast."
Australia
Xiaomei
The price is ฿2,047
฿2,663 total
includes taxes & fees
25 Nov - 26 Nov
Le Stanze del Principe
A large, arched stone entrance with a metal gate, a sign indicating a public space, and a chain barrier in front.

12. Domus Milone

Domus Milone
Naples City Centre, 0.7 km from Palazzo dello Spagnuolo
9.6 out of 10, Exceptional, (29 reviews)
"Very nice, clean and reasonably priced B&B. Massimo and Angela were super friendly and helpful. Excellent location, very walkable to all the sites in Naples. Highly recommend!"
Canada
Pasquale
The price is ฿2,292
฿2,932 total
includes taxes & fees
20 Nov - 21 Nov
Domus Milone
A bakery display with various baked goods and a coffee station.

13. Leone Camere D'autore CENTRO STORICO

Leone Camere D'autore CENTRO STORICO
Historical Center, 0.6 km from Palazzo dello Spagnuolo
9.6 out of 10, Exceptional, (7 reviews)
"Brilliant stay. Perfect walkable location for almost all attractions. Would definitely stay again. "
Canada
Angelique
The price is ฿2,888
฿3,587 total
includes taxes & fees
16 Nov - 17 Nov
Leone Camere D'autore CENTRO STORICO
A courtyard with a stone floor, arched doorways, and potted plants.

14. 5 Santi Rooms

5 Santi Rooms
Decumani, 0.5 km from Palazzo dello Spagnuolo
9.6 out of 10, Exceptional, (10 reviews)
"The room was spacious and clean. Good amenities and modern bathroom. Staff were friendly as well."
United Kingdom
Rachel
The price is ฿1,925
฿2,528 total
includes taxes & fees
17 Nov - 18 Nov
5 Santi Rooms
A hotel room with a bed, a large mirror, and a painting of a building.

15. La Dimora Di Parthenope

La Dimora Di Parthenope
Rione Sanità, 0.2 km from Palazzo dello Spagnuolo
9.8 out of 10, Exceptional, (10 reviews)
"Great stay in Naples! The accommodation was clean, had excellent Wi-Fi, and was conveniently located near the city center. The host and the staff member were very friendly and helpful. Great value for the price. Highly recommended!"
Germany
Hussein
The price is ฿1,271
฿4,293 total
includes taxes & fees
20 Nov - 21 Nov
La Dimora Di Parthenope
A breakfast setup with bread, milk, and orange juice on a table, with outdoor seating and greenery in the background.

16. Borgo Vergini Garden

Borgo Vergini Garden
Rione Sanità, < 0.1 km from Palazzo dello Spagnuolo
9.6 out of 10, Exceptional, (26 reviews)
"Nice place to stay that is walking distance to many things. Staff was very pleasant and helpful and a great breakfast spread is made each morning. There is a delicious pizza joint right across the street. "
United States
Amanda
The price is ฿3,565
฿4,332 total
includes taxes & fees
19 Nov - 20 Nov
Borgo Vergini Garden
A modern bedroom with a wooden floor, a bed with a beige quilt, a dining table with chairs, a sofa, and a kitchen area in the background.

17. Toto e Peppino luxury rooms

Toto e Peppino luxury rooms
Rione Sanità, < 0.1 km from Palazzo dello Spagnuolo
9.6 out of 10, Exceptional, (13 reviews)
"Antonio was a great host. He helped with all our questions and even helped us book proper transport to and from airport and including to our other stay in sorrento."
United States
aylin
The price is ฿2,208
฿2,839 total
includes taxes & fees
16 Nov - 17 Nov
Toto e Peppino luxury rooms
A corridor with a wooden door at the end, flanked by arches and a tiled floor.

18. Maison Mimì

Maison Mimì
Decumani, 0.5 km from Palazzo dello Spagnuolo
9.4 out of 10, Exceptional, (20 reviews)
"Very new renovation. They are still putting the finishing touches on it. Centrally located."
United States
Matt
The price is ฿3,056
฿3,772 total
includes taxes & fees
15 Dec - 16 Dec
Maison Mimì
A courtyard with a staircase leading to a building with classical architecture, including columns and statues.

19. Alma Regina Relais

Alma Regina Relais
Decumani, 0.5 km from Palazzo dello Spagnuolo
9.4 out of 10, Exceptional, (26 reviews)
"The room was great, location was very good and the staff was super helpful when we arrived early"
Canada
Sarah
The price is ฿3,949
฿4,754 total
includes taxes & fees
30 Nov - 1 Dec
Alma Regina Relais
A narrow hallway with a dining table set for a meal, a bookshelf, and a hanging plant.

20. Monart Hospitality Cavour

Monart Hospitality Cavour
Rione Sanità, 0.3 km from Palazzo dello Spagnuolo
9.4 out of 10, Exceptional, (78 reviews)
"Amazing location. Monica was super helpful in every way. Will be back for sure."
Canada
Mahnoor
The price is ฿3,647
฿4,423 total
includes taxes & fees
18 Nov - 19 Nov
Monart Hospitality Cavour
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Other attractions near Palazzo dello Spagnuolo

Museo delle Arti Sanitarie e Di Storia della Medicina

You can browse the exhibits at Museo delle Arti Sanitarie e Di Storia della Medicina, a museum with a storied past, during your holiday in Naples. Take in the fascinating museums in this culturally rich area.
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Top Palazzo dello Spagnuolo Hotel Reviews

A hallway with framed black and white photographs on the wall, a white door, and a decorative archway with a relief sculpture.
Naplesuite

Naplesuite

Naplesuite
Naples City Centre

10/10 Excellent

Fantastic location. Safe, very central and could walk to everything. Lots nearby. Yet very quiet in the room. Staff incredibly friendly and helpful. Room lovely, clean and spacious. Highly recommend this place for a central stay.
United Kingdom
Deborah
Reviewed September 25, 2026
Naplesuite

Frequently Asked Questions

What's the area like around Palazzo dello Spagnuolo?

Palazzo dello Spagnuolo is located in a historic area of Naples known for its top museums. If you're looking for a convenient place to stay, take a look at the 2537 hotels and other accommodation options you'll find within a mile.

What's the best hotel to stay near Palazzo dello Spagnuolo?

Adjacent to Palazzo dello Spagnuolo, Le Stanze del Principe is one of the top choices for your stay based on our traveller data, and this B&B offers free breakfast and free WiFi. Other good options within a short distance include UNA Hotels Napoli and Starhotels Terminus.

How many hotels can I expect to find near Palazzo dello Spagnuolo?

Expedia has 2537 hotels and other accommodation options within a mile from Palazzo dello Spagnuolo.

If I need to cancel the hotel reservation for my stay near Palazzo dello Spagnuolo, will I receive a refund?

Yes! The majority of hotel room reservations are refundable provided that you cancel prior to the hotel's cancellation deadline, which in most cases is within 24 or 48 hours of your arrival date. If you have a reservation that's non-refundable, you might be able to still cancel and be given a refund within a 24-hour period of booking. Put your dates in and click on "Search", then use the filter option "fully refundable" to get the best deals available near Palazzo dello Spagnuolo.

What can I see and do near Palazzo dello Spagnuolo?

You'll want to browse the collections at Royal Palace, Museum Madre and Museo delle Arti Sanitarie e Di Storia della Medicina. While you're exploring, swing by Naples Cathedral, Naples Underground and Sansevero Chapel Museum to learn a bit about the area. You can catch a show at Teatro di San Carlo, Teatro Palapartenope and Teatro Stabile Napoli.

How can I get to Palazzo dello Spagnuolo?

With so many choices for transport, exploring the area around Palazzo dello Spagnuolo is simple. You can walk to nearby metro stations including Toledo Station, Municipio Station and Università Station. If you're taking a train into town, Montesanto Station and Napoli Marittima Station are the closest stations to Historical Center.