The Best Hotels in North Central, San Antonio - 2026 Updated Prices

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Our top choices for North Central hotels

A hotel lobby with a reception desk, wooden flooring, and a coffee station.

1. La Quinta Inn By Wyndham IH-10 West San Antonio TX

North Central

José

฿2,113 total

includes taxes & fees

15 Nov - 16 Nov

A spacious lobby with a central staircase, seating area, and large windows.

2. San Antonio Marriott Northwest Medical Center

Medical Center District, 2.4 km from North Central

Hsiao Tung

฿3,757 total

includes taxes & fees

6 Dec - 7 Dec

A buffet with various food items, including omelets and other dishes, served in metal containers.

3. Holiday Inn Express San Antonio-Airport by IHG

4.3 km from North Central

Lori

฿4,050 total

includes taxes & fees

29 Nov - 30 Nov

A modern lobby with a sofa, patterned chairs, a central ottoman, and a chandelier.

4. Drury Plaza Hotel San Antonio Airport

4.4 km from North Central

Erica

฿4,571 total

includes taxes & fees

15 Nov - 16 Nov

A multi-level hotel atrium with a central courtyard, outdoor seating, and a swimming pool.

5. Estancia del Norte San Antonio, Tapestry Collection by Hilton

3.9 km from North Central

Lauro

฿5,064 total

includes taxes & fees

29 Nov - 30 Nov

A modern lobby with seating areas, a stone accent wall, and a wooden ceiling.

6. Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Uptown Central, 4.6 km from North Central

Elsa

฿3,170 total

includes taxes & fees

8 Nov - 9 Nov

A modern kitchen with a central island, built-in appliances, and a coffee station.

7. Wyndham Garden San Antonio Airport

Uptown Central, 4.6 km from North Central

Johnny

฿3,306 total

includes taxes & fees

15 Nov - 16 Nov

A hotel dining area with multiple tables and chairs, a counter with a coffee machine, and a view of the outside through large windows.

8. La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

Medical Center District, 3.7 km from North Central

Gilbert

฿3,561 total

includes taxes & fees

8 Nov - 9 Nov

A spacious lobby with a modern design, featuring a large seating area with sofas and armchairs, a patterned rug, and a reception desk.

9. Comfort Inn and Suites Near Medical Center

2 km from North Central

Amy

฿2,332 total

includes taxes & fees

15 Nov - 16 Nov

A spacious hotel lobby with a long marble reception desk, multiple seating areas, and a large television screen.

10. Hampton Inn & Suites San Antonio-Airport

Uptown Central, 4.6 km from North Central

Omar

฿3,328 total

includes taxes & fees

15 Nov - 16 Nov

A modern bar area with wooden bar counters, black bar stools, and pendant lighting.

11. Courtyard by Marriott Medical Center San Antonio

Medical Center District, 5.2 km from North Central

Francisca

฿3,573 total

includes taxes & fees

13 Nov - 14 Nov

12. Hyatt Place San Antonio - Riverwalk

Downtown San Antonio, 9.3 km from North Central

Allen

฿4,786 total

includes taxes & fees

22 Nov - 23 Nov

13. Embassy Suites San Antonio Riverwalk-Downtown

Downtown San Antonio, 8.6 km from North Central

Ludmila

฿5,586 total

includes taxes & fees

22 Nov - 23 Nov

A spacious lobby with multiple seating areas, a central coffee table, and a view of the upper floors.

14. Drury Inn & Suites San Antonio Northwest Medical Center

Medical Center District, 5.3 km from North Central

Samuel

฿3,609 total

includes taxes & fees

12 Nov - 13 Nov

15. Omni La Mansion del Rio

Downtown San Antonio, 8.8 km from North Central

jenny

฿6,643 total

includes taxes & fees

25 Nov - 26 Nov

An outdoor pool area with a stone wall, a water fountain, and a bridge connecting different levels.

16. Drury Plaza Hotel San Antonio Riverwalk

Downtown San Antonio, 8.9 km from North Central

Felicia

฿5,132 total

includes taxes & fees

15 Nov - 16 Nov

A spacious foyer with a staircase, large windows, and a chandelier.

17. Days Inn by Wyndham San Antonio Airport

Uptown Central, 5.3 km from North Central

LUCERO

฿2,398 total

includes taxes & fees

9 Nov - 10 Nov

A spacious living area with a dark blue sofa, four grey armchairs, and three metallic coffee tables.

18. La Quinta Inn & Suites by Wyndham San Antonio Airport

4.6 km from North Central

Vanesa

฿3,176 total

includes taxes & fees

12 Nov - 13 Nov

A modern living room with a grey sofa, orange armchairs, a coffee table, and a fireplace.

19. Best Western Plus Downtown North

8.9 km from North Central

Vanesa

฿3,508 total

includes taxes & fees

12 Nov - 13 Nov

A modern indoor pool area with glass railings, seating, and a bar area with screens.

20. Hyatt Regency San Antonio Riverwalk

Downtown San Antonio, 8.8 km from North Central

Donna M

฿7,534 total

includes taxes & fees

22 Nov - 23 Nov

View all properties

Compare popular hotels in North Central

Property	Property class	Guest rating
La Quinta Inn By Wyndham IH-10 West San Antonio TX	3.0 star property	6.2 1,001 reviews	View
San Antonio Marriott Northwest Medical Center	3.5 star property	8.6 Excellent 1,193 reviews	View
Holiday Inn Express San Antonio-Airport by IHG	2.5 star property	9.4 Exceptional 1,005 reviews	View
Drury Inn & Suites San Antonio Northwest Medical Center	3.0 star property	9.2 Wonderful 1,522 reviews	View
Courtyard by Marriott Medical Center San Antonio	3.0 star property	8.8 Excellent 1,002 reviews	View

Where to stay in North Central

Find the best North Central areas for the activities you enjoy most.

A boat tour on a canal with a bridge in the background.

Downtown San Antonio

Explore the network of pedestrian paths that follows the beautiful San Antonio River to discover restaurants and bars, gift shops, galleries and museums.

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A riverside walkway adorned with colorful umbrellas and festive lights.

Uptown Central

If you're spending some time in Uptown Central, Marion Koogler McNay Art Museum and Alamo Quarry Market are top sights worth seeing.

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A riverside walkway with colorful umbrellas, a stone bridge, and historic buildings.

Far West Side

While visiting Far West Side, you might make a stop by sights like Aquatica San Antonio Waterpark and Hill Country Golf Club.

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A cityscape with a prominent tower, a large body of water, and a sunset.

Medical Center District

While Medical Center District isn't home to many top sights, Wonderland of the Americas Mall and Huebner Oaks are some notable places to visit nearby.

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A historic stone building with a central arched doorway, a flagpole with a flag, and a paved courtyard.

Northwest Side

If you're spending some time in Northwest Side, Huebner Oaks and Crystal Ice Palace are top sights worth seeing.

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Top North Central Hotel Reviews

Drury Plaza Hotel San Antonio Airport

Uptown Central

10/10 Excellent

Julie

Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

Uptown Central

10/10 Excellent

Angus

Hyatt Place San Antonio - Riverwalk

Downtown San Antonio

10/10 Excellent

We had a wonderful stay at this hotel. Location was perfect, you walk out the backdoor and you're straight on to the River walk. Riverwalk was beautiful with lots of restaurants and bars, its also immaculate. We walked back late at night and felt totally safe. Rooms were also immaculate and very large with all the amenities you need. I would agree with others re the toilet being small, but we didn't experience water on the floor from the shower. Breakfast was lovely and we managed to get a seat...

Angela

Courtyard by Marriott Medical Center San Antonio

Medical Center District

10/10 Excellent

Andrew

Hampton Inn & Suites San Antonio-Airport

Uptown Central

10/10 Excellent

Marcus

Omni La Mansion del Rio

Downtown San Antonio

10/10 Excellent

laura Kathryn

Drury Plaza Hotel San Antonio Riverwalk

Downtown San Antonio

10/10 Excellent

Fabulous location, friendly staff, huge room. Did decline housekeeping for one day, but didn’t get it for either, not a huge issue but communication maybe? Breakfast had a good choice (apart from this morning when by 945am everything had been cleared apart from cold hardboiled eggs and cheese) Evening ‘canopies’ is a full on meal - over our 3 evenings there were nachos, fajitas, hot dogs, pasta, jacket potatoes and includes 3 alcoholic drinks if you want them. Right on the RiverWalk made it...

Sarah

A riverboat with a pink and blue exterior, surrounded by buildings with balconies and a palm tree.

Hotel Valencia Riverwalk, Valencia Collection

Downtown San Antonio

10/10 Excellent

Terry

Hyatt Regency San Antonio Riverwalk

Downtown San Antonio

10/10 Excellent

Sarah

A spacious lobby with a high ceiling, exposed beams, and a staircase. There are seating areas with sofas and a coffee table, and a large rug on the floor.

Drury Plaza Hotel San Antonio North Stone Oak

Stone Oak

10/10 Excellent

Breanna

A reception area with a modern design, featuring a reception desk, a digital screen, and a view of an old building through a stone archway.

La Quinta Inn & Suites by Wyndham San Antonio Downtown

Downtown San Antonio

10/10 Excellent

David

Frequently Asked Questions

What's it like in North Central?

North Central is a welcoming neighbourhood known for its cosy cafes and sporting events.

Where is the best place to stay in North Central?

Based on Expedia customer reviews, La Quinta Inn By Wyndham IH-10 West San Antonio TX is the highest ranked property in North Central. This hotel offers free breakfast and an outdoor pool.

How many hotels are there in North Central?

Expedia has 21 hotels and other accommodation options in North Central to choose from, making this an ideal home base for exploring the greater San Antonio area.

If I need to cancel my hotel reservation in North Central, will I receive a refund?

Yes! You'll find that most hotel bookings are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your arrival date. If you have a reservation that's non-refundable, you may still be able to cancel and be given a refund within 24 hours of your booking. Enter your dates, click on "Search", then filter by "fully refundable" to get the best deals in North Central.

What can I see and do in this San Antonio neighbourhood?

A few places to visit in the area around North Central include Rah Rah Room, San Pedro Driving Range & Par 3 Course and Wonderland of the Americas Mall. While you're out sightseeing in San Antonio, make sure that you visit other sights such as Norris Conference Centers - San Antonio or Laugh Out Loud Comedy Club.

Search Hotels in North Central, San Antonio

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for North Central hotels

1. La Quinta Inn By Wyndham IH-10 West San Antonio TX

2. San Antonio Marriott Northwest Medical Center

3. Holiday Inn Express San Antonio-Airport by IHG

4. Drury Plaza Hotel San Antonio Airport

5. Estancia del Norte San Antonio, Tapestry Collection by Hilton

6. Heritage Inn & Suites San Antonio Airport, Trademark Wyndham

7. Wyndham Garden San Antonio Airport

8. La Quinta Inn & Suites by Wyndham San Antonio Medical Ctr NW

9. Comfort Inn and Suites Near Medical Center

10. Hampton Inn & Suites San Antonio-Airport

11. Courtyard by Marriott Medical Center San Antonio

12. Hyatt Place San Antonio - Riverwalk

13. Embassy Suites San Antonio Riverwalk-Downtown

14. Drury Inn & Suites San Antonio Northwest Medical Center

15. Omni La Mansion del Rio

16. Drury Plaza Hotel San Antonio Riverwalk

17. Days Inn by Wyndham San Antonio Airport

18. La Quinta Inn & Suites by Wyndham San Antonio Airport

19. Best Western Plus Downtown North

20. Hyatt Regency San Antonio Riverwalk

Compare popular hotels in North Central

Where to stay in North Central

Downtown San Antonio

Uptown Central

Far West Side

Medical Center District

Northwest Side

Top North Central Hotel Reviews

Drury Plaza Hotel San Antonio Airport

10/10 Excellent

Frequently Asked Questions

What's it like in North Central?

Where is the best place to stay in North Central?

How many hotels are there in North Central?

If I need to cancel my hotel reservation in North Central, will I receive a refund?

What can I see and do in this San Antonio neighbourhood?