Mission Bay Packages (Flight + Hotel)

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to ฿27,000 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Where to stay in Mission Bay

Find the best Mission Bay areas and neighborhoods for the activities you enjoy most. Learn more about Mission Bay
A cityscape with tall buildings, palm trees, and red double-decker buses.

Union Square

Fashion puts on its finest face in one of the country’s largest shopping plazas.

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Top hotels in Mission Bay

LUMA Hotel San Francisco

LUMA Hotel San Francisco

4 out of 5
100 Channel Street San Francisco CA
Fully refundableReserve now, pay when you stay
The price is ฿7,144 per night from 26 Nov to 27 Nov
฿7,144
฿8,408 total
26 Nov - 27 Nov
includes taxes & fees
LUMA Hotel San Francisco
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
Fully refundableReserve now, pay when you stay
The price is ฿4,018 per night from 22 Nov to 23 Nov
฿4,018
฿4,729 total
22 Nov - 23 Nov
includes taxes & fees
9/10 Wonderful! (6,439 reviews)
"There is no pen or notebook in the room that’s very important this my first hotel without"

Reviewed on 27 Oct 2026

Holiday Inn Golden Gateway by IHG
Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
2500 Mason St San Francisco CA
Fully refundableReserve now, pay when you stay
The price is ฿3,389 per night from 23 Nov to 24 Nov
฿3,389
฿5,380 total
23 Nov - 24 Nov
includes taxes & fees
9/10 Wonderful! (7,753 reviews)
"Great breakfast! Comfortable beds."

Reviewed on 27 Oct 2026

Hotel Riu Plaza Fisherman's Wharf
See all 4,369 properties in Mission Bay
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently asked questions

How much does a Mission Bay holiday package cost?
Custom make your Mission Bay holiday package from as low as . Pick from any combination of hotels, flights and rental cars to build the getaway you've been dreaming of. Be sure to add on a few activities!
How do I get a cheap travel package to Mission Bay?
Bundle your flights and hotels, throw in extras such as activities or a rental car, and save with a Mission Bay holiday package. You won't just pick up big discounts on your adventure — you'll have a world of choice too. When you book with Expedia, you'll have your pick of over 550 airlines and 1,000,000 hotels all over the world. Your next epic adventure begins right here, right now!
Where should I stay in Mission Bay?
A trip to Mission Bay isn't complete without seeing Pier 39 and Alcatraz Island. Reserve a room close by and easily access these popular tourist attractions.
How far in advance should I book my Mission Bay holiday?
Smart travellers often book as early as possible. You can usually compare international fares on Expedia up to 12 months before your flight. If you've left booking to the last minute, fear not. Budget prices sometimes appear just weeks before departure dates.
What does an Expedia Mission Bay travel package include?
Choose from a combination of hotels, rental cars and flights. Once you've made your booking, you can also add on activities and tours. Want to pick your airfare class? That's possible too. The choice is all yours when it comes to putting together your perfect Mission Bay trip.
What should I know before booking a Mission Bay travel package?
You'll pick up great savings when you bundle your flights, hotels and rental cars into a package. Not only that, booking everything in one place makes trip planning much easier. So why waste your time or money? Whether you're organising an upscale romantic escape or a budget solo adventure, explore our package deals today.
Can I choose my airline with a Mission Bay Expedia holiday package?
You can, and with more than 550 airlines to choose from worldwide, you're not short on choice. Scroll through the available options and find out which airline best suits your needs and budget.
If I'm not able to travel, can I cancel my Mission Bay holiday package?
Plans can change unexpectedly, so yes, you can. You may be able to cancel and rebook your Mission Bay holiday package for free within 24 hours of booking. For bookings made more than 24 hours ago, you can still make the necessary changes, but your airline, hotel or car rental company may impose a fee. Want more information? Take a look at our Customer Service Portal. We'll help make sure your getaway goes off without a hitch.

Stay near popular Mission Bay attractions

Chase Center

8.8/10 (1,176 reviews)
Catch an event at Chase Center during your trip to San Francisco. Amble around this vibrant area's Chinatown or experience its fascinating museums.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.