The Best Hotels Closest to Mcleod Regional Medical Center in Florence - 2026 Updated Prices

A modern building with a curved glass facade, surrounded by a well-maintained lawn and several trees.

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Our top choices for Mcleod Regional Medical Center hotels

A spa room with two armchairs, a small table with a vase of flowers, and a sign that reads "SPA Florence".

A restaurant with brick walls, framed awards, and a bar area.

A spacious living room with a wooden floor, a ceiling fan, and a dining area with a wooden table and chairs.

An outdoor patio area with a brick wall, a covered seating area with string lights, and potted plants.

1. Hotel Florence, Tapestry Collection by Hilton

0.8 km from Mcleod Regional Medical Center

Ankh

฿4,676

฿5,238 total

includes taxes & fees

30 Oct - 31 Oct

2. Rodeway Inn Florence Downtown

1.2 km from Mcleod Regional Medical Center

฿1,434

฿1,655 total

includes taxes & fees

22 Nov - 23 Nov

A modern kitchen with stainless steel appliances, a gray sofa, and a ceiling fan.

A modern living room with a brick wall, a grey sofa, a wooden coffee table, and a view through large windows.

A modern kitchen with grey cabinets, stainless steel appliances, and bar stools.

A modern living room with a grey sofa, a round coffee table, a grey armchair with patterned cushions, a floor lamp, and a large TV mounted on the wall.

3. The Urban Flats

0.8 km from Mcleod Regional Medical Center

฿9,651

฿15,871 total

includes taxes & fees

27 Oct - 28 Oct

A spacious lobby with a checkered floor, a reception desk, and a chandelier.

A vending area with snack and drink options, including Pepsi refrigerators and a 'MARKET' display with various products.

A two-story building with a brick facade, a flat roof, and a covered entrance area.

A spacious dining area with multiple tables and chairs, large windows offering a view of the parking lot, and a television mounted on the wall.

4. Howard Johnson by Wyndham Florence

5.5 km from Mcleod Regional Medical Center

Alanda

฿2,052

฿2,298 total

includes taxes & fees

25 Oct - 26 Oct

A modern living room with a grey sofa, two black hanging chairs, a small table, and a TV mounted on the wall.

A modern hotel with a 'Park Inn by Radisson' sign, featuring a covered entrance, multiple windows, and a parking lot.

A modern living room with a grey sofa, a flat-screen TV, geometric wall art, and a bookshelf with decorative items.

A hotel room with a large bed, a desk with a lamp, a chair, a TV, and a window with curtains.

5. Park Inn by Radisson Florence, SC

5.5 km from Mcleod Regional Medical Center

Amy

฿3,046

฿3,411 total

includes taxes & fees

1 Nov - 2 Nov

A hotel lobby with a reception desk, seating area, and a television screen.

A hotel room with a sectional sofa, two ottomans, a bed with a green bedspread, and framed pictures on the wall.

A hotel room with a bed, a sofa, an ottoman, and a lamp.

A spacious dining area with multiple tables and chairs, large windows, and a flat-screen TV mounted on the wall.

6. Comfort Inn & Suites Florence Center Area

7 km from Mcleod Regional Medical Center

Mila

฿3,415

฿3,825 total

includes taxes & fees

15 Nov - 16 Nov

A spacious hotel lobby with multiple seating areas, including tables and chairs, a reception desk, and a staircase leading to an upper level.

A lobby with leather sofas, a coffee table, potted plants, and a reception desk.

An indoor swimming pool with clear water, surrounded by a checkered wall pattern, and equipped with multiple seating areas and a lifeguard station.

A Hampton Inn & Suites hotel with a well-lit entrance, multiple floors, and a parking area.

7. Hampton Inn & Suites Florence-North-I-95

5.7 km from Mcleod Regional Medical Center

Ladavish

฿4,130

฿4,626 total

includes taxes & fees

2 Nov - 3 Nov

A swimming pool with lounge chairs and a view of the outdoors.

A hotel room with two beds, a desk with a TV, and a bathroom visible through an open door.

A Holiday Inn Express hotel with a covered entrance and a clear sign indicating a clearance of 14'6'.

A buffet with various food items, including omelets and baked goods, served in metal containers.

8. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

9.1 km from Mcleod Regional Medical Center

Christopher

฿4,117

฿4,945 total

includes taxes & fees

8 Nov - 9 Nov

A spacious lobby with a reception desk, seating area, and large windows.

An indoor swimming pool with clear poolside areas, a lifeguard station, and a view of the outside.

A Hilton Garden Inn with a large, multi-story building, a covered entrance, and a parking lot.

A reception area with a counter, a sign for 'The Pavilion Pantry', and a green wall.

9. Hilton Garden Inn Florence

7.2 km from Mcleod Regional Medical Center

Derrick

฿3,989

฿4,468 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with two beds, a desk with chairs, a television, and artwork on the walls.

A modern lounge area with a sofa, armchairs, and small tables.

A reception area with a wooden desk, a map on the wall, and a sign welcoming visitors to Florence, SC.

A modern hotel room with a kitchenette, a grey sofa, a dining area, and a sign that reads "A Great Day Starts With Breakfast."

10. TownePlace Suites by Marriott Florence

7 km from Mcleod Regional Medical Center

Crystal

฿3,702

฿4,146 total

includes taxes & fees

15 Nov - 16 Nov

A fire pit surrounded by chairs and tables, with a staircase leading to an entrance, and a large window with a curtain.

A hotel with a modern architectural design, featuring a prominent entrance canopy and a sign indicating it is a Staybridge Suites hotel.

A modern kitchen with two islands, overhead lighting, and a stone backsplash.

A modern kitchen with dark wooden cabinets, a stainless steel refrigerator, a microwave, and a coffee maker. There is a dining area with two red chairs and a table.

11. Staybridge Suites Florence - Civic Center by IHG

8.1 km from Mcleod Regional Medical Center

Tishia

฿4,421

฿4,951 total

includes taxes & fees

15 Nov - 16 Nov

A hotel room with a desk, chair, bed, and a yellow sofa.

A hotel dining area with wooden tables and chairs, a fireplace, and a television.

A hotel room with a fireplace, a television, a sofa, a patterned carpet, and large windows offering a view of the outside.

A reception desk with a stone wall backdrop, a sign reading 'Quality Choice Hotels,' and a reception area with a wooden reception desk and two chairs.

12. Quality Inn & Suites Florence Civic Center

7.5 km from Mcleod Regional Medical Center

Sharhonda

฿3,007

฿3,367 total

includes taxes & fees

3 Nov - 4 Nov

A hotel entrance with a stone facade, glass doors, and a number '501' above.

A corner market with shelves stocked with snacks and beverages, and two large refrigerators.

An indoor swimming pool with a tiled floor, a pool ladder, and lounge chairs.

A hotel reception area with a wooden floor, a reception desk, a seating area with chairs, and a decorative wall with a tree pattern.

13. Fairfield Inn & Suites by Marriott Florence I-20

6.9 km from Mcleod Regional Medical Center

Alma

฿3,987

฿4,465 total

includes taxes & fees

1 Nov - 2 Nov

A spacious lobby with a high ceiling, a central seating area, and a staircase leading to an upper level.

A modern breakfast area with a buffet setup, including a microwave, coffee maker, and various food items.

A La Quinta Inn & Suites hotel with a modern facade, a well-lit entrance, and a landscaped garden area.

A hotel room with a bed, sofa, TV, and a desk.

14. La Quinta Inn & Suites by Wyndham Florence

5.7 km from Mcleod Regional Medical Center

Brenda

฿2,887

฿3,234 total

includes taxes & fees

25 Oct - 26 Oct

A multi-story hotel with a prominent entrance and signage for Springhill Suites by Marriott.

An indoor swimming pool with clear blue water, surrounded by green chairs and a tiled floor.

A modern kitchen with a built-in coffee station, a refrigerator, and a seating area with a patterned rug.

A hotel room with two beds, a wooden headboard, a window with curtains, and a wall-mounted air conditioner.

15. SpringHill Suites by Marriott Florence

7.2 km from Mcleod Regional Medical Center

John

฿3,423

฿4,035 total

includes taxes & fees

26 Oct - 27 Oct

A spacious lobby with a high ceiling, a central seating area with armchairs and a coffee table, a flat-screen TV, and a dining area with tables and chairs.

A spacious lobby with a large seating area, a flat-screen TV, and a fireplace.

A modern hotel lobby with a fireplace, seating area, and a reception desk.

A modern hotel lobby with a central seating area, a large abstract painting, and a patterned carpet.

16. Residence Inn Marriott Florence

7.2 km from Mcleod Regional Medical Center

Teri

฿3,617

฿4,052 total

includes taxes & fees

1 Nov - 2 Nov

A hotel lobby with a wooden floor, multiple dining tables, chairs, and a seating area with a sofa.

A lobby with a fireplace, seating area, and a television.

A hotel lobby with a reception desk, seating area, and a welcome mat.

A Hampton Inn & Suites with a large sign, brick facade, and a parking lot.

17. Hampton Inn & Suites Florence Center

7.2 km from Mcleod Regional Medical Center

William

฿3,157

฿3,536 total

includes taxes & fees

15 Nov - 16 Nov

A Holiday Inn Express & Suites hotel with a covered entrance, palm trees, and a clear sky.

A coffee station with two coffee machines and a display of coffee pods and cups.

A hotel room with a large bed, a desk with a chair, a television, and a walk-in closet.

A buffet with labeled trays of turkey sausage and cookies.

18. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

8 km from Mcleod Regional Medical Center

Leigh

฿3,613

฿4,046 total

includes taxes & fees

22 Nov - 23 Nov

A hotel with a modern design, multiple floors, and a parking lot.

A restaurant with a bar area, seating, and a kitchen visible in the background.

A swimming pool with lounge chairs and a building with balconies in the background.

A hotel room with a checkered sofa, a bed, a desk, and a framed picture on the wall.

19. Best Western Inn

4.7 km from Mcleod Regional Medical Center

Steward Heikes

฿3,003

฿3,364 total

includes taxes & fees

25 Oct - 26 Oct

A modern hotel with a covered entrance, large windows, and a sign indicating it is a hotel.

A bar area with a neon sign, shelves of bottles, and a view of trees through large windows.

A modern kitchen with a white countertop, three black stools, and a red accent wall.

20. Aloft by Marriott Florence

7.6 km from Mcleod Regional Medical Center

Darlene

฿3,752

฿4,404 total

includes taxes & fees

3 Nov - 4 Nov

View all properties

Compare top hotels near Mcleod Regional Medical Center

Hotel Florence, Tapestry Collection by Hilton 0.8 km from Mcleod Regional Medical Center View	Rodeway Inn Florence Downtown 1.2 km from Mcleod Regional Medical Center View	Howard Johnson by Wyndham Florence 5.5 km from Mcleod Regional Medical Center View	Park Inn by Radisson Florence, SC 5.5 km from Mcleod Regional Medical Center View	Comfort Inn & Suites Florence Center Area 7 km from Mcleod Regional Medical Center View
8.8 Excellent 658 reviews	5.4 8 reviews	8.6 Excellent 2,749 reviews	9.0 Wonderful 2,478 reviews	9.0 Wonderful 1,374 reviews
฿4,676 ฿5,238 total includes taxes & fees 30 Oct - 31 Oct	฿1,434 ฿1,655 total includes taxes & fees 22 Nov - 23 Nov	฿2,052 ฿2,298 total includes taxes & fees 25 Oct - 26 Oct	฿3,046 ฿3,411 total includes taxes & fees 1 Nov - 2 Nov	฿3,415 ฿3,825 total includes taxes & fees 15 Nov - 16 Nov

Top Mcleod Regional Medical Center Hotel Reviews

Hyatt Place Florence Downtown

10/10 Excellent

"This spot is always on point.. I was even given the VIP Customer package…"

TownePlace Suites by Marriott Florence

8/10 Good

"Hannah at the desk was very sweet. I was disappointed that there was no body lotion provided. Also, the were 2 tissues in the box. Otherwise, bed was very cozy."

La Quinta Inn & Suites by Wyndham Florence

10/10 Excellent

"Close to the restaurants and shopping."

Days Inn by Wyndham Florence Near Civic Center

8/10 Good

"Room was great, but the complimentary breakfast was very poor."

Hotel Florence, Tapestry Collection by Hilton

8/10 Good

"The staff were great!! Parking was close by and easy. The restaurant bar was a great stop. If you want a refrigerator in your room you need to ask prior to arrival."

Frequently asked questions

What's the area like around Mcleod Regional Medical Center?

Mcleod Regional Medical Center is located in a welcoming area of Florence known for its array of dining options. If you're looking for a convenient place to stay, take a look at the 18 hotels and other accommodation options you'll find within a mile.

What's the best place to stay near Mcleod Regional Medical Center?

Hyatt Place Florence Downtown is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and a restaurant. It's located just a short 0.4 mi (0.7 km) from Mcleod Regional Medical Center. Other good options within a short distance include Hotel Florence, Tapestry Collection by Hilton and The Urban Flats.

How many hotels can I expect to find near Mcleod Regional Medical Center?

Expedia has 18 hotels and other accommodation options within a mile from Mcleod Regional Medical Center.

If I need to cancel the hotel reservation for my stay near Mcleod Regional Medical Center, will I receive a refund?

Yes! You'll find that most hotel reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which in most cases is within 24 or 48 hours of your scheduled arrival. If you have a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of your booking. Enter your dates, click on "Search", then use the filter option "fully refundable" to view top deals close to Mcleod Regional Medical Center.

What can I see and do near Mcleod Regional Medical Center?

You can enjoy live performances at FMU Performing Arts Center and Florence Little Theatre. You might spend a leisurely day outdoors at Florence Veterans Park and Greenwood Baseball Park and Playground. Create some family memories at Sky Zone Trampoline Park and Tilt Studio.

Search Hotels Near Mcleod Regional Medical Center, Florence

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Our top choices for Mcleod Regional Medical Center hotels

1. Hotel Florence, Tapestry Collection by Hilton

2. Rodeway Inn Florence Downtown

3. The Urban Flats

4. Howard Johnson by Wyndham Florence

5. Park Inn by Radisson Florence, SC

6. Comfort Inn & Suites Florence Center Area

7. Hampton Inn & Suites Florence-North-I-95

8. Holiday Inn Express & Suites Florence I-95 @ Hwy 327 by IHG

9. Hilton Garden Inn Florence

10. TownePlace Suites by Marriott Florence

11. Staybridge Suites Florence - Civic Center by IHG

12. Quality Inn & Suites Florence Civic Center

13. Fairfield Inn & Suites by Marriott Florence I-20

14. La Quinta Inn & Suites by Wyndham Florence

15. SpringHill Suites by Marriott Florence

16. Residence Inn Marriott Florence

17. Hampton Inn & Suites Florence Center

18. Holiday Inn Express & Suites Florence I-95 & I-20 Civic Ctr by IHG

19. Best Western Inn

20. Aloft by Marriott Florence

Compare top hotels near Mcleod Regional Medical Center

Hotel Florence, Tapestry Collection by Hilton

Rodeway Inn Florence Downtown

Howard Johnson by Wyndham Florence

Park Inn by Radisson Florence, SC

Comfort Inn & Suites Florence Center Area

Top Mcleod Regional Medical Center Hotel Reviews

Hyatt Place Florence Downtown

TownePlace Suites by Marriott Florence

La Quinta Inn & Suites by Wyndham Florence

Days Inn by Wyndham Florence Near Civic Center

Hotel Florence, Tapestry Collection by Hilton

Frequently asked questions