The Best Hotels Closest to Lexington Medical Center in West Columbia - 2026 Updated Prices

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Our top choices for Lexington Medical Center hotels

An outdoor patio area with wicker furniture, a circular fire pit, and umbrellas.

A compact kitchen with a microwave, dishwasher, and refrigerator.

A coffee station with multiple coffee dispensers and a mug.

A hotel room with a large bed, a desk with a chair, a small table, a chair, a lamp, and a window with curtains.

1. TownePlace Suites Columbia West/Lexington

0.5 km from Lexington Medical Center

Michael

฿4,378

฿4,729 total

includes taxes & fees

18 Oct - 19 Oct

A patio area with wicker furniture, a central fire pit, and outdoor umbrellas.

A modern kitchen with a central island, bar stools, and a coffee station with various containers.

A modern bar area with a marble countertop, multiple bar stools, and a large flat-screen TV mounted on the wall.

A spacious lobby with a large seating area, a coffee table, and a potted plant.

2. Hilton Garden Inn Columbia Airport

0.5 km from Lexington Medical Center

Russell

฿3,869

฿4,178 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a bed, a desk with a computer, a nightstand, a lamp, and a window with curtains.

A conference room with long tables and chairs, a projector screen, a storage area, and a carpeted floor.

A hotel room with a desk, a black office chair, a brown sofa, a TV displaying a movie, and a wall with framed artwork.

A modern kitchen with stainless steel appliances, a dining table with red chairs, and wooden cabinets.

3. Residence Inn Columbia West/Lexington

0.4 km from Lexington Medical Center

Jennifer

฿4,412

฿4,765 total

includes taxes & fees

12 Oct - 13 Oct

A hotel lobby with a brown sofa, a small table, a refrigerator stocked with snacks, a staircase with a green wall, and a dining area in the background.

A restaurant with wooden tables and chairs, a counter with a coffee machine, and a TV mounted on the wall.

A hotel room with a bed, a desk with a TV, a chair, and a mirror.

A hotel room with a desk, a flat-screen TV, a microwave, and a lamp.

4. Sleep Inn Columbia

2.8 km from Lexington Medical Center

George

฿2,834

฿3,061 total

includes taxes & fees

26 Oct - 27 Oct

A modern building entrance with a brick pathway leading to a glass door.

A snack display with various chips and packaged snacks.

A gym with treadmills, stationary bikes, and weight machines.

A modern kitchen with a central island, bar stools, and a dining area with tables and chairs.

5. Hampton Inn Columbia-I-26 Airport

0.7 km from Lexington Medical Center

Vicky

฿3,399

฿3,747 total

includes taxes & fees

13 Oct - 14 Oct

A spacious lobby with a high ceiling, a staircase, a large sofa, a coffee table, and a TV mounted on the wall.

A hotel with a swimming pool, outdoor seating, and a modern architectural design.

A bar area with a television, red bar stools, and a red carpeted floor.

A hotel room with two beds, a large mirror, a vanity with a sink, and a towel rack.

6. Doubletree by Hilton Columbia, SC

3 km from Lexington Medical Center

Donna

฿3,286

฿3,626 total

includes taxes & fees

1 Nov - 2 Nov

A hotel room with a sofa, a small table, a bed, and a painting on the wall.

A gym with treadmills, elliptical machines, and stationary bikes.

A lobby with a reception desk, two armchairs, a television, and a Coca-Cola vending machine.

A modern hotel lobby with seating, a coffee station, and a dining area.

7. Best Western Executive Inn & Suites

2.6 km from Lexington Medical Center

Sandra

฿3,704

฿4,001 total

includes taxes & fees

7 Oct - 8 Oct

A hotel reception desk with a 'Comfort Inn' sign, a digital screen, and a 'Welcome' mat.

A hotel room with two beds, a desk, a lamp, and a window with curtains.

A spacious restaurant with multiple dining areas, a kitchen in the background, and a flat-screen TV mounted on the wall.

A Comfort Inn hotel with a clear entrance, multiple floors, and a parking lot.

8. Comfort Inn Columbia West

2.9 km from Lexington Medical Center

Dalton

฿2,576

฿2,885 total

includes taxes & fees

30 Oct - 31 Oct

A reception area with a stone mosaic wall, a wooden reception desk, and a counter with a green top. There are framed certificates on the wall and a vending machine to the right.

A hotel with a brick facade, a covered entrance, and a sign for Quality Inn.

A bathroom with a granite sink, a large mirror, a shower with a glass door, and a towel rack.

A hotel room with two beds, a green wall, and a blue curtain.

9. Quality Inn Columbia Airport

2.8 km from Lexington Medical Center

Jmesha

฿2,118

฿2,288 total

includes taxes & fees

4 Nov - 5 Nov

A bar area with wooden chairs, a counter with a computer, and a seating area with a sofa and chairs.

A restaurant with wooden chairs and tables, a bar area with a minibar, and a seating area with a sofa and cushions.

A hotel room with a bed, bedside lamps, a nightstand, and a bathtub.

A spacious lobby with a tiled floor, striped armchairs, a blue ottoman, and a flat-screen TV mounted on a stone wall.

10. Clarion Inn Columbia Airport

2.7 km from Lexington Medical Center

HECTOR

฿2,007

฿2,168 total

includes taxes & fees

25 Oct - 26 Oct

A living room with a sofa, chairs, a coffee table, a TV, and a radiator.

A spacious living area with a high ceiling, a dining table with chairs, a sofa, and a large plant.

A Knights Inn with a stone facade, a red awning, and a signboard.

A hotel room with a bed, a sofa, a desk, and a TV.

11. Knights Inn Columbia

2.6 km from Lexington Medical Center

Raheeam

฿2,694

฿2,910 total

includes taxes & fees

7 Oct - 8 Oct

A hotel room with two beds, a desk with a computer, a chair, and a view of the outdoors.

A hotel reception area with a Baymont Inn & Suites sign, a reception desk, a clock, and a seating area with chairs and a table.

A hotel fitness center with treadmills, elliptical machines, and a weight rack.

A hotel room with a desk, two armchairs, a sofa, a television, a coffee maker, and a mirror.

12. Baymont by Wyndham Columbia Northwest

3 km from Lexington Medical Center

Judy

฿1,788

฿1,931 total

includes taxes & fees

8 Oct - 9 Oct

A swimming pool with two lanes, surrounded by lounge chairs and a fence.

A breakfast counter with a sign reading "Daybreak Breakfast," a coffee machine, a syrup dispenser, and a display of cereal boxes.

A modern lobby with a black marble floor, a blue sofa, a brown leather chair, and a large window with a view of the street.

A hotel lobby with a reception desk, a leather sofa, a TV mounted on the wall, and a marble floor.

13. Days Inn by Wyndham Columbia

2.8 km from Lexington Medical Center

Tilisha

฿1,947

฿2,180 total

includes taxes & fees

1 Nov - 2 Nov

A modern living room with a grey sofa, a coffee table, and a dining area with a table and chairs.

A modern kitchen with white cabinets, a central island, and a dining area with a wooden table and benches.

A hotel room with two single beds, a window with blinds, a wall-mounted artwork, and a nightstand with a lamp.

A modern kitchen with white cabinetry, a built-in dishwasher, and a large island.

14. Columbia Duet Unit B

2.9 km from Lexington Medical Center

฿6,811

฿29,328 total

includes taxes & fees

11 Oct - 12 Oct

A dining area with a wooden table, chairs, and a lamp. There is a plant on a shelf and a TV mounted on the wall.

A living room with a sofa, armchair, coffee table, fireplace, TV, and a dining area in the background.

A neatly arranged bedroom with a large bed, a window with curtains, a bedside table with a lamp, and a mirror on the wall.

A living room with a fireplace, a sofa, a TV, and a door.

15. Columbia Duet - 2 Units

2.9 km from Lexington Medical Center

฿12,797

฿49,883 total

includes taxes & fees

11 Oct - 12 Oct

A modern hotel lobby with a large dining table, multiple seating areas, and a large screen wall.

A modern kitchen area with a long counter, various food items, and a chalkboard with food-related drawings.

A snack and beverage kiosk with shelves stocked with various snacks and drinks, a chalkboard with writing, and a large circular sign with the word 'TREATS'.

A hotel room with a bed, desk, chair, air conditioning unit, and a window with a view of trees.

16. Hampton Inn & Suites Lexington Columbia

5.5 km from Lexington Medical Center

Jean

฿3,997

฿4,437 total

includes taxes & fees

11 Oct - 12 Oct

A modern living room with a blue cabinet, a blue sofa, a round coffee table, and patterned ottomans.

A hotel lobby with a modern chandelier, a reception desk, and a staircase with decorative railings.

Two people celebrating with confetti in a bar setting.

A hotel named 'Hotel Trundle' with a brick facade, American and another flag, and potted plants in front.

17. Hotel Trundle

7.2 km from Lexington Medical Center

Wendy

฿4,838

฿5,419 total

includes taxes & fees

18 Oct - 19 Oct

A spacious indoor area with a long table, multiple chairs, and a seating area with sofas and a TV.

A spacious lobby with modern furniture, a decorative partition, and a visible kitchen area.

A modern living room with a fireplace, comfortable seating, and large windows.

A hotel room with a bed, a nightstand, a lamp, and a view of the outside.

18. The Lantern Hotel Columbia

7.2 km from Lexington Medical Center

Theresa

฿5,305

฿5,941 total

includes taxes & fees

18 Oct - 19 Oct

An outdoor patio with a stone fire pit, seating, and a covered area with lights.

A modern reception area with a large digital display, a counter, and vending machines.

A hotel room with a modern design, featuring a large bed, a desk, and a seating area with a tray table.

A modern hotel lobby with a curved sofa, dining area, and a kitchen in the background.

19. Springhill Suites by Marriott Columbia near Fort Jackson

15.4 km from Lexington Medical Center

Leslie

฿3,231

฿3,618 total

includes taxes & fees

11 Oct - 12 Oct

A modern hotel room with a large bed, a seating area, and a TV.

A hotel room with a sofa, a small table, a bed, and a TV mounted on the wall.

A modern kitchen with a central island, wooden cabinets, a built-in washer and dryer, and a view of the city.

A multi-story hotel with a modern design, featuring a prominent vertical stripe pattern on the facade.

20. Homewood Suites By Hilton Columbia Downtown

6.3 km from Lexington Medical Center

Brian

฿4,253

฿4,763 total

includes taxes & fees

18 Oct - 19 Oct

View all properties

Compare popular hotels close to Lexington Medical Center

Property	Property class	Guest rating
TownePlace Suites Columbia West/Lexington	9.2 Wonderful 505 reviews	View
Hilton Garden Inn Columbia Airport	9.0 Wonderful 1,005 reviews	View
Residence Inn Columbia West/Lexington	9.2 Wonderful 424 reviews	View
Sleep Inn Columbia	8.2 Very good 1,199 reviews	View
Hampton Inn Columbia-I-26 Airport	8.2 Very good 1,001 reviews	View

Top Lexington Medical Center Hotel Reviews

Tru By Hilton Columbia Greystone

10/10 Excellent

"The lobby, halls and room smelled very fresh and clean. The only disappointment was no coffee in the rooms."

Tru By Hilton Columbia Downtown

10/10 Excellent

"Hotel is conveniently located. Had everything we needed. And breakfast was way better than expected! Would not hesitate to stay here again. Breakfast staff seemed to really be "on the ball" and care about what they were doing!"

Quality Inn Columbia Airport

8/10 Good

"The staff was consistently excellent. The room smelled of 1974. I accidentally got a smoking room. It is a very affordable and nice place. Worth it"

Extended Stay America Suites Columbia West Interstate 126

8/10 Good

"The Staff makes up for the other issues. I rented a room for my elderly uncle while he waits for housing and they have went above and beyond; they listen and answer all questions."

Hilton Garden Inn Columbia Airport

10/10 Excellent

"Room very clean ."

Knights Inn Columbia

10/10 Excellent

"Help with checking in"

Clarion Inn Columbia Airport

8/10 Good

"👍"

Lexington Expo Hotel by IHG

10/10 Excellent

"Parking to breakfast was great."

Executive Inn

10/10 Excellent

"It didn’t look like much when I pulled up , but for the money you can’t beat it. The staff was so friendly and helpful , the room was CLEAN and it was nice and quiet. Perfect for just a place to sleep peacefully."

Frequently asked questions

What's the area like around Lexington Medical Center?

Lexington Medical Center is located in West Columbia. Travellers like the surrounding area for its bars. If you're looking for a convenient place to stay, take a look at the 15 hotels and other accommodation options you'll find within a mile.

Where is the best place to stay near Lexington Medical Center?

Adjacent to Lexington Medical Center, Hilton Garden Inn Columbia Airport is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and free parking. Other good choices within a short distance include Hampton Inn Columbia-I-26 Airport and Residence Inn Columbia West/Lexington.

How many hotels are there near Lexington Medical Center?

Expedia has 15 hotels and other accommodation options within a mile from Lexington Medical Center.

If I need to cancel the hotel reservation for my stay near Lexington Medical Center, will I receive a refund?

Yes! The majority of hotel reservations are fully refundable if you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of your check-in date. If you have a reservation that's non-refundable, you might still have the option to cancel and receive a refund within a 24-hour period of booking. Put your dates in and click on "Search", then use the filter option "fully refundable" to review the best options available near Lexington Medical Center.

What can I see and do near Lexington Medical Center?

Study the collections at South Carolina State Museum, Columbia Museum of Art or Robert Mills Historic House and Park. While you're exploring, swing by First Baptist Church, South Carolina State House and Imara Woman to learn a bit about the area. You can check out the local talent at Koger Center for the Arts, Township Auditorium and Town Theatre.

Search Hotels Near Lexington Medical Center, West Columbia

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Treat yourself

Be picky

Check prices for these dates

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Our top choices for Lexington Medical Center hotels

1. TownePlace Suites Columbia West/Lexington

2. Hilton Garden Inn Columbia Airport

3. Residence Inn Columbia West/Lexington

4. Sleep Inn Columbia

5. Hampton Inn Columbia-I-26 Airport

6. Doubletree by Hilton Columbia, SC

7. Best Western Executive Inn & Suites

8. Comfort Inn Columbia West

9. Quality Inn Columbia Airport

10. Clarion Inn Columbia Airport

11. Knights Inn Columbia

12. Baymont by Wyndham Columbia Northwest

13. Days Inn by Wyndham Columbia

14. Columbia Duet Unit B

15. Columbia Duet - 2 Units

16. Hampton Inn & Suites Lexington Columbia

17. Hotel Trundle

18. The Lantern Hotel Columbia

19. Springhill Suites by Marriott Columbia near Fort Jackson

20. Homewood Suites By Hilton Columbia Downtown

Compare popular hotels close to Lexington Medical Center

Top Lexington Medical Center Hotel Reviews

Tru By Hilton Columbia Greystone

Tru By Hilton Columbia Downtown

Quality Inn Columbia Airport

Extended Stay America Suites Columbia West Interstate 126

Hilton Garden Inn Columbia Airport

Knights Inn Columbia

Clarion Inn Columbia Airport

Lexington Expo Hotel by IHG

Executive Inn

Frequently asked questions