The Best Hotels Closest to Guana Tolomato Matanzas National Estuarine Research Reserve in Ponte Vedra Beach - 2026 Updated Prices

Change your mind
Book hotels with free cancellation
Treat yourself
Sign in to save 10% or more on thousands of hotels
Sign in
Be picky
Search almost a million properties worldwide

Check prices for these dates

Tonight

Tomorrow

Next weekend

In two weeks

Our top choices for Guana Tolomato Matanzas National Estuarine Research Reserve hotels

A modern breakfast area with a self-service counter, seating, and a beverage station.

A modern hotel building with a prominent 'tru by Hilton' sign, multiple floors, and a well-lit entrance.

A modern office space with a red and blue seating area, a computer desk, and a large window providing a view of the outdoors.

A modern hotel reception area with a curved desk, a large digital screen, and a seating area with blue cushions.

1. Tru By Hilton St. Augustine I-95

14.6 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Jennifer

฿3,258

฿3,633 total

includes taxes & fees

4 Oct - 5 Oct

An upper front porch with a white floor, black railings, and two rocking chairs.

A bookshelf with various books, a brick wall, and a door.

A two-story building with a dark blue exterior and a white trim, featuring a large window and a flag.

A Zora Suite with a bed, a desk with a plant, a white furry rug, and a painting on the wall.

2. Zora's Sojourn

15 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Daniela

฿3,380

฿4,700 total

includes taxes & fees

27 Sept - 28 Sept

A spacious hotel lobby with a reception desk, seating area with sofas, and a large window providing natural light.

A spacious dining area with a long table and multiple chairs, a bar area with shelves of bottles, and a seating area with a sofa and chairs.

A spacious hotel lobby with a modern design, featuring a reception desk, seating area with sofas and chairs, and a large television on the wall.

A modern hotel room with a bed, a sofa, a desk, and a round table.

3. Comfort Suites St. Augustine Historic District Area

11.5 km from Guana Tolomato Matanzas National Estuarine Research Reserve

kenneth

฿3,384

฿3,774 total

includes taxes & fees

30 Sept - 1 Oct

A wooden gazebo with a balcony, a staircase, and outdoor seating.

A pool area with lounge chairs, a red umbrella, and palm trees.

A spacious dining area with multiple tables and chairs, a kitchen in the background, and a large window with curtains.

A hotel room with two beds, a desk, a TV, and a bathroom.

4. The Bayfront Inn

14.9 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Danielle

฿4,216

฿4,701 total

includes taxes & fees

27 Sept - 28 Sept

A two-story house with a porch, a front door, and a small front yard with plants.

A bedroom with a large bed, a ceiling fan, a window with shutters, and a dresser.

A living room with a large flat-screen TV mounted on a wall, a wooden dresser, a gray sofa, and a hallway leading to another room.

A kitchen with a dishwasher, a sink, and a countertop with various items. There are shelves above the countertop holding glasses and a pitcher.

5. Carriage Way Inn

14.3 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Christopher

฿5,176

฿5,771 total

includes taxes & fees

28 Sept - 29 Sept

A modern kitchen with white countertops, a stainless steel sink, a coffee maker, and a window with a view of the outside.

A neatly made bed with a headboard, two bedside tables with lamps, a window with a view, and a wall with a tropical leaf mural.

A modern kitchen with wooden cabinets, a stainless steel refrigerator, a flat-screen TV, and a dining area with pink chairs.

A modern kitchen with wooden cabinets, a stainless steel refrigerator, a coffee maker, and a pink chair.

6. Haleys Court Boutique Motel

12.2 km from Guana Tolomato Matanzas National Estuarine Research Reserve

John

฿2,704

฿4,877 total

includes taxes & fees

29 Sept - 30 Sept

An indoor swimming pool with a wooden ceiling, clear pool area, and lounge chairs.

A beach with people walking along the shore.

A modern cafe with seating areas, a coffee station, and a view of the outdoors.

A hotel room with a bed, a desk, a chair, a window with a view, and a ceiling fan.

7. Holiday Inn Express St. Augustine - Vilano Beach by IHG

12.2 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Jonathan

฿4,107

฿4,980 total

includes taxes & fees

25 Oct - 26 Oct

A reception area with leather sofas, a glass coffee table, and a reception desk.

A building with a blue roof and a sign that reads "Regency Inn & Suites".

A hotel room with two beds, a small round table, a sofa, and a bathroom visible through an open door.

An indoor swimming pool with tiled flooring, lounge chairs, and windows with views.

8. Regency Inn & Suites

19.3 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Joel

฿2,229

฿2,485 total

includes taxes & fees

27 Sept - 28 Sept

An aerial view of a beach with a long pier extending into the ocean, adjacent to a sandy shore with buildings and parked cars.

A hotel with a pool, parking, and a view of the beach.

An aerial view of a rectangular swimming pool with a tiled deck, surrounded by palm trees and a covered seating area.

A dining area with wooden tables and chairs, a kitchen in the background, and a ceiling fan.

9. Ocean Breeze Inn

19.2 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Ashley

฿2,229

฿2,485 total

includes taxes & fees

27 Sept - 28 Sept

A building with a covered porch, outdoor lighting, and greenery.

A bathroom with a wooden vanity, a sink, a mirror, a microwave, and a coffee maker.

A hotel room with two beds, a desk, and a kitchenette.

A two-story building with a white exterior and a brick staircase.

10. Quality Inn St Augustine Historic District Area

11.8 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Weston

฿1,960

฿2,186 total

includes taxes & fees

4 Oct - 5 Oct

A hotel room with a bed, a TV mounted on the wall, a desk, and a sofa.

A laundry facility with two stacked front-loading washing machines.

A swimming pool with lounge chairs and umbrellas, surrounded by trees.

A Marriott hotel with a parking lot and a clear sky.

11. Fairfield Inn & Suites by Marriott St. Augustine I-95

14.2 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Fletcher

฿3,202

฿3,571 total

includes taxes & fees

1 Oct - 2 Oct

A spacious lobby with a marble floor, a reception desk, and a large wall mural.

A hotel lobby with a seating area featuring green armchairs, a round coffee table, and a bar area in the background.

A modern hotel with a covered entrance, palm trees, and a clear blue sky.

A modern cafe interior with a central table, counter, and various food and drink dispensers.

12. Hampton Inn St. Augustine Downtown Historic District

13.2 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Jose

฿3,203

฿3,572 total

includes taxes & fees

12 Oct - 13 Oct

A modern bar area with a counter, seating, and various amenities.

A swimming pool with lounge chairs and umbrellas, surrounded by trees and a fence.

A hotel room with a bed, bedside tables, a TV, a painting, and a desk.

A hotel lobby with a seating area, a kitchenette, a door, and a wall-mounted artwork.

13. Courtyard by Marriott St Augustine I-95

14.2 km from Guana Tolomato Matanzas National Estuarine Research Reserve

jonathan

฿2,526

฿2,816 total

includes taxes & fees

1 Oct - 2 Oct

A balcony with two chairs and a table, overlooking a beach and buildings.

A spacious lobby with a dining area, a seating area with a sofa and armchairs, and a balcony with decorative railings.

A spacious kitchen area with a central island, equipped with various appliances and a coffee station.

An aerial view of a fortified structure with a central courtyard, surrounded by walls and a moat.

14. Hampton Inn & Suites St. Augustine-Vilano Beach

12.3 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Sandra

฿3,258

฿3,633 total

includes taxes & fees

18 Oct - 19 Oct

A building with a door, a sign, and a Pepsi sign.

A kitchen with granite countertops, a refrigerator, and a coffee machine.

An outdoor seating area with tables and chairs, a covered pavilion, and an American flag.

A kitchen with a granite countertop, a coffee machine, and a refrigerator. There are two potted plants with red flowers on the counter.

15. Budget Inn St. Augustine

14.7 km from Guana Tolomato Matanzas National Estuarine Research Reserve

thomas

฿2,137

฿2,383 total

includes taxes & fees

27 Sept - 28 Sept

A hotel with a pool, a covered entrance, and a sign for 'City Express by Marriott.'

A hotel room with two beds, a TV, and artwork on the wall.

A modern hotel lobby with a reception desk, seating area, and a bookshelf.

A modern dining area with tables and chairs, a kitchen area with a yellow and white chevron pattern wall, and a counter with various items.

16. City Express By Marriott St. Augustine

12.1 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Cathy

฿2,805

฿3,127 total

includes taxes & fees

30 Sept - 1 Oct

A modern kitchen with white cabinets and a stainless steel oven.

A modern bedroom with a wooden ceiling, a large bed with patterned bedding, a nightstand, and a decorative fish sculpture on the wall.

A marina with multiple boats docked, a large building with balconies, and a view of the water and sunset.

A living room with a sofa, coffee table, and a view of a marina through a glass door.

17. Inn at Camachee Harbor by Coolvacay

12.1 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Robert

฿3,489

฿3,890 total

includes taxes & fees

27 Sept - 28 Sept

A covered porch with white chairs and red flooring, featuring American flags and hanging plants.

A two-story house with a porch decorated with Christmas lights and wreaths.

A room with a red sofa, a round table, and a chandelier. There is a mirror, a chair, and a lamp. The room has patterned wallpaper and a wooden floor.

A dining room with a round table, two chairs, a chandelier, and a large stained glass window.

18. Cedar House Inn

14.8 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Sue

฿6,651

฿7,416 total

includes taxes & fees

28 Sept - 29 Sept

An outdoor patio with a striped sofa, yellow chairs, and a table.

A modern hotel lobby with a sofa, chairs, a table, and a TV.

A modern kitchen with a microwave, stove, and sink, a dining area with a table and chairs, and a living area with a sofa and a TV.

A hotel room with a sofa, a bedside table with a lamp, a bed with a headboard, and a wall with a patterned wallpaper.

19. Home2 Suites by Hilton St. Augustine I-95

14.1 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Sean

฿4,627

฿5,159 total

includes taxes & fees

4 Oct - 5 Oct

A hotel room with two beds, a desk, a chair, a mirror, and artwork on the wall.

A restaurant interior with booths and tables, menu boards, and a coffee station.

A reception area with a counter, a TV, and a self-service kiosk.

20. Days Inn by Wyndham St. Augustine I-95/Outlet Mall

14.4 km from Guana Tolomato Matanzas National Estuarine Research Reserve

Roberta

฿2,139

฿2,385 total

includes taxes & fees

4 Oct - 5 Oct

View all properties

Compare popular hotels close to Guana Tolomato Matanzas National Estuarine Research Reserve

Property	Property class	Guest rating
Tru By Hilton St. Augustine I-95	9.4 Exceptional 459 reviews	View
Zora's Sojourn	10.0 Exceptional 14 reviews	View
Comfort Suites St. Augustine Historic District Area	9.2 Wonderful 1,816 reviews	View
The Bayfront Inn	9.4 Exceptional 1,008 reviews	View
Carriage Way Inn	9.8 Exceptional 879 reviews	View

Top Guana Tolomato Matanzas National Estuarine Research Reserve Hotel Reviews

The Flagler Inn

10/10 Excellent

"Great location. Close to Old downtown. Hotel is quite."

DoubleTree by Hilton St. Augustine Historic District

10/10 Excellent

"5"

Other attractions near Guana Tolomato Matanzas National Estuarine Research Reserve

Guana Pine State Park and Wildlife Management Area

8.6/10 (9 reviews)

Explore the lovely green spaces of Guana Pine State Park and Wildlife Management Area and enjoy the golf courses in Ponte Vedra Beach. Wander the beautiful beaches and seaside in the area.

See properties

South Ponte Vedra Beach

Why not spend a lazy afternoon at South Ponte Vedra Beach during your trip to Ponte Vedra Beach?

See properties

Guana River Wildlife Management Area

You can take time to visit Guana River Wildlife Management Area during your travels to Ponte Vedra Beach.

See properties

Water + Stone Gallery

You can browse the exhibits at Water + Stone Gallery, a museum with a storied past, during your travels to St. Augustine. Wander the beautiful beaches and seaside in the area.

See properties

Castle Otttis

8.8/10 (8 reviews)

Castle Otttis is just one of the places to see in St. Augustine, so why not enjoy the other things to explore during your travels? Wander the beautiful beaches and seaside in the area.

See properties

Usina Beach

Why not spend a care-free afternoon at Usina Beach during your travels in Ponte Vedra Beach?

See properties

The Schoolyard

The Schoolyard is just one of the places to see in Nocatee, so why not enjoy the other things to explore during your travels?

See properties

Frequently asked questions

What's the area like around Guana Tolomato Matanzas National Estuarine Research Reserve?

Guana Tolomato Matanzas National Estuarine Research Reserve is located in a family-friendly area of Ponte Vedra Beach known for its interesting historical sites and major shopping area. If you're looking for a convenient place to stay, take a look at the 48 hotels and other accommodation options you'll find within a mile.

What's the best hotel to stay close to Guana Tolomato Matanzas National Estuarine Research Reserve?

Comfort Suites St. Augustine Historic District Area is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and an outdoor pool. You'll find it 7.1 mi (11.5 km) from Guana Tolomato Matanzas National Estuarine Research Reserve.

How many hotels should I expect to find close to Guana Tolomato Matanzas National Estuarine Research Reserve?

Expedia has 48 hotels and other accommodation options within a mile from Guana Tolomato Matanzas National Estuarine Research Reserve.

If I need to cancel the hotel reservation for my stay near Guana Tolomato Matanzas National Estuarine Research Reserve, will I receive a refund?

Yes, most hotel room reservations are refundable if you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you have a reservation that's non-refundable, you might be able to cancel it and receive a refund within 24 hours of your booking. Plug in your dates, click on "Search", then filter by "fully refundable" to review the best deals available near Guana Tolomato Matanzas National Estuarine Research Reserve.

Search Hotels Near Guana Tolomato Matanzas National Estuarine Research Reserve, Ponte Vedra Beach

Change your mind

Treat yourself

Be picky

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for Guana Tolomato Matanzas National Estuarine Research Reserve hotels

1. Tru By Hilton St. Augustine I-95

2. Zora's Sojourn

3. Comfort Suites St. Augustine Historic District Area

4. The Bayfront Inn

5. Carriage Way Inn

6. Haleys Court Boutique Motel

7. Holiday Inn Express St. Augustine - Vilano Beach by IHG

8. Regency Inn & Suites

9. Ocean Breeze Inn

10. Quality Inn St Augustine Historic District Area

11. Fairfield Inn & Suites by Marriott St. Augustine I-95

12. Hampton Inn St. Augustine Downtown Historic District

13. Courtyard by Marriott St Augustine I-95

14. Hampton Inn & Suites St. Augustine-Vilano Beach

15. Budget Inn St. Augustine

16. City Express By Marriott St. Augustine

17. Inn at Camachee Harbor by Coolvacay

18. Cedar House Inn

19. Home2 Suites by Hilton St. Augustine I-95

20. Days Inn by Wyndham St. Augustine I-95/Outlet Mall

Compare popular hotels close to Guana Tolomato Matanzas National Estuarine Research Reserve

Top Guana Tolomato Matanzas National Estuarine Research Reserve Hotel Reviews

The Flagler Inn

DoubleTree by Hilton St. Augustine Historic District

Other attractions near Guana Tolomato Matanzas National Estuarine Research Reserve

Guana Pine State Park and Wildlife Management Area

South Ponte Vedra Beach

Guana River Wildlife Management Area

Water + Stone Gallery

Castle Otttis

Usina Beach

The Schoolyard

Frequently asked questions